(-)-epigallocatechin 3-gallate multiple interactions ISO RGD:730973 6480464 epigallocatechin gallate inhibits the reaction [1 more ... CTD PMID:30092300 (R)-mevalonic acid multiple interactions EXP 6480464 Mevalonic Acid inhibits the reaction [Simvastatin promotes the reaction [SREBF2 protein binds to PON1 promoter]] CTD PMID:14500290 (R)-mevalonic acid multiple interactions ISO RGD:1307751 6480464 Mevalonic Acid inhibits the reaction [Atorvastatin results in increased expression of SREBF2 mRNA], Mevalonic Acid inhibits the reaction [Simvastatin results in increased expression of SREBF2 mRNA] CTD PMID:12056585 1,2-dimethylhydrazine decreases expression ISO RGD:730973 6480464 1, 2-Dimethylhydrazine results in decreased expression of SREBF2 mRNA CTD PMID:22206623 1,3-dichloropropan-2-ol increases expression EXP 6480464 1 more ... CTD PMID:29305303 1,3-dichloropropan-2-ol increases expression ISO RGD:730973 6480464 1 more ... CTD PMID:30092300 1,3-dichloropropan-2-ol multiple interactions ISO RGD:730973 6480464 epigallocatechin gallate inhibits the reaction [1 more ... CTD PMID:30092300 1,3-dichloropropan-2-ol multiple interactions EXP 6480464 alliin inhibits the reaction [1 more ... CTD PMID:29305303 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile multiple interactions EXP 6480464 Citalopram results in increased cleavage of and results in increased activity of SREBF2 protein CTD PMID:16324787 17beta-hydroxy-5alpha-androstan-3-one increases expression ISO RGD:730973 6480464 Dihydrotestosterone results in increased expression of SREBF2 mRNA CTD PMID:16990341 17beta-hydroxy-5alpha-androstan-3-one increases expression EXP 6480464 Dihydrotestosterone results in increased expression of SREBF2 mRNA CTD PMID:16541421 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:730973 6480464 Tetrachlorodibenzodioxin inhibits the reaction [2 more ... CTD PMID:21851831 2,2',4,4',5,5'-hexachlorobiphenyl decreases expression ISO RGD:730973 6480464 2 more ... CTD PMID:20005886 , PMID:21851831 2,3',4,4',5-Pentachlorobiphenyl increases expression ISO RGD:730973 6480464 2 more ... CTD PMID:31388691 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:730973 6480464 Tetrachlorodibenzodioxin affects the expression of SREBF2 mRNA CTD PMID:21570461 , PMID:24058054 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:1307751 6480464 Tetrachlorodibenzodioxin results in decreased expression of SREBF2 mRNA CTD PMID:21215274 more ... 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:730973 6480464 Tetrachlorodibenzodioxin results in decreased expression of SREBF2 mRNA CTD PMID:20005886 more ... 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:730973 6480464 Tetrachlorodibenzodioxin inhibits the reaction [2 more ... CTD PMID:21851831 2,3,7,8-Tetrachlorodibenzofuran decreases expression ISO RGD:1307751 6480464 2 more ... CTD PMID:32109520 2,6-dinitrotoluene affects expression ISO RGD:1307751 6480464 2, 6-dinitrotoluene affects the expression of SREBF2 mRNA CTD PMID:21346803 2-hydroxypropanoic acid increases expression EXP 6480464 Lactic Acid results in increased expression of SREBF2 mRNA CTD PMID:30851411 25-hydroxycholesterol multiple interactions EXP 6480464 25-hydroxycholesterol inhibits the reaction [[Resveratrol results in increased activity of and results in increased cleavage of SREBF2 protein] which results in increased expression of LDLR mRNA] more ... CTD PMID:17052361 more ... 25-hydroxycholesterol decreases activity EXP 6480464 25-hydroxycholesterol results in decreased activity of SREBF2 protein CTD PMID:17052361 5-fluorouracil decreases expression EXP 6480464 Fluorouracil results in decreased expression of SREBF2 mRNA CTD PMID:34151400 acetamide decreases expression ISO RGD:1307751 6480464 acetamide results in decreased expression of SREBF2 mRNA CTD PMID:31881176 acrolein multiple interactions EXP 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of SREBF2 mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of SREBF2 mRNA CTD PMID:32699268 acrylamide multiple interactions ISO RGD:730973 6480464 Acrylamide inhibits the reaction [Streptozocin results in increased expression of SREBF2 mRNA] CTD PMID:34896238 acrylamide decreases expression ISO RGD:730973 6480464 Acrylamide results in decreased expression of SREBF2 mRNA CTD PMID:34896238 aflatoxin B1 decreases methylation EXP 6480464 Aflatoxin B1 results in decreased methylation of SREBF2 intron CTD PMID:30157460 aldehydo-D-glucose increases expression EXP 6480464 Glucose results in increased expression of SREBF2 protein CTD PMID:23647015 aldehydo-D-glucose multiple interactions EXP 6480464 Allopurinol inhibits the reaction [Glucose results in increased expression of SREBF2 protein] more ... CTD PMID:23647015 aldehydo-D-glucose increases expression ISO RGD:1307751 6480464 Glucose results in increased expression of SREBF2 protein CTD PMID:23647015 aldehydo-D-glucose multiple interactions ISO RGD:1307751 6480464 Allopurinol inhibits the reaction [Glucose results in increased expression of SREBF2 protein] more ... CTD PMID:23647015 all-trans-retinoic acid decreases expression EXP 6480464 Tretinoin results in decreased expression of SREBF2 mRNA CTD PMID:23724009 all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of SREBF2 mRNA CTD PMID:33167477 alliin multiple interactions EXP 6480464 alliin inhibits the reaction [1 more ... CTD PMID:29305303 allopurinol multiple interactions EXP 6480464 Allopurinol inhibits the reaction [Glucose results in increased expression of SREBF2 protein] CTD PMID:23647015 allopurinol multiple interactions ISO RGD:1307751 6480464 Allopurinol inhibits the reaction [Glucose results in increased expression of SREBF2 protein] more ... CTD PMID:23647015 alpha-pinene multiple interactions EXP 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of SREBF2 mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of SREBF2 mRNA CTD PMID:32699268 amitriptyline multiple interactions EXP 6480464 Amitriptyline results in increased cleavage of and results in increased activity of SREBF2 protein CTD PMID:16324787 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [Lipopolysaccharides results in increased expression of SREBF2 protein], pyrazolanthrone inhibits the reaction [Quercetin results in increased metabolism of and affects the localization of SREBF2 protein] CTD PMID:22388943 , PMID:33677747 aristolochic acid decreases expression EXP 6480464 aristolochic acid I results in decreased expression of SREBF2 mRNA CTD PMID:33212167 aspartame multiple interactions ISO RGD:730973 6480464 [Fats, Unsaturated co-treated with Sodium Glutamate co-treated with Aspartame] affects the expression of SREBF2 mRNA CTD PMID:23783067 atorvastatin calcium multiple interactions ISO RGD:1307751 6480464 Atorvastatin results in increased activity of and results in increased localization of SREBF2 protein, Mevalonic Acid inhibits the reaction [Atorvastatin results in increased expression of SREBF2 mRNA] CTD PMID:12056585 atorvastatin calcium increases expression ISO RGD:1307751 6480464 Atorvastatin results in increased expression of SREBF2 mRNA CTD PMID:12056585 , PMID:12065722 atorvastatin calcium increases localization EXP 6480464 Atorvastatin results in increased localization of SREBF2 protein CTD PMID:11728391 atrazine increases expression EXP 6480464 Atrazine results in increased expression of SREBF2 mRNA CTD PMID:22378314 benzalkonium chloride increases expression EXP 6480464 Benzalkonium Compounds results in increased expression of SREBF2 mRNA CTD PMID:26919959 benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of SREBF2 mRNA CTD PMID:20106945 benzo[a]pyrene increases methylation ISO RGD:730973 6480464 Benzo(a)pyrene results in increased methylation of SREBF2 intron CTD PMID:27901495 beta-cyclodextrin multiple interactions EXP 6480464 betadex inhibits the reaction [SREBF2 protein results in increased abundance of Cholesterol] more ... CTD PMID:33677747 bezafibrate increases expression EXP 6480464 Bezafibrate results in increased expression of SREBF2 mRNA CTD PMID:14685799 bisphenol A affects expression ISO RGD:730973 6480464 bisphenol A affects the expression of SREBF2 mRNA, bisphenol A affects the expression of SREBF2 protein CTD PMID:21932408 bisphenol A increases response to substance ISO RGD:730973 6480464 SREBF2 mRNA results in increased susceptibility to bisphenol A CTD PMID:27502578 bisphenol A multiple interactions EXP 6480464 SREBF2 promotes the reaction [bisphenol A results in increased expression of NPC1L1 mRNA] more ... CTD PMID:28057006 , PMID:31270304 bisphenol A decreases methylation ISO RGD:730973 6480464 bisphenol A results in decreased methylation of SREBF2 gene, bisphenol A results in decreased methylation of SREBF2 promoter CTD PMID:27502578 , PMID:31470036 bisphenol A affects methylation ISO RGD:730973 6480464 bisphenol A affects the methylation of SREBF2 promoter CTD PMID:27334623 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of SREBF2 mRNA, bisphenol A results in increased expression of SREBF2 protein CTD PMID:28057006 , PMID:29275510 bisphenol A multiple interactions ISO RGD:730973 6480464 SREBF2 mRNA promotes the reaction [bisphenol A results in increased expression of FASN mRNA] CTD PMID:27502578 bisphenol A increases expression ISO RGD:1307751 6480464 bisphenol A results in increased expression of SREBF2 mRNA CTD PMID:25181051 , PMID:30816183 bisphenol A increases expression ISO RGD:730973 6480464 bisphenol A results in increased expression of SREBF2 more ... CTD PMID:25168180 more ... cadmium atom increases expression ISO RGD:1307751 6480464 Cadmium results in increased expression of SREBF2 mRNA CTD PMID:17066326 cadmium atom multiple interactions ISO RGD:1307751 6480464 [Streptozocin co-treated with Cadmium] results in increased expression of SREBF2 protein, myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of SREBF2 protein] CTD PMID:25240712 cadmium dichloride increases expression ISO RGD:1307751 6480464 Cadmium Chloride results in increased expression of SREBF2 mRNA CTD PMID:17066326 caffeine multiple interactions EXP 6480464 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine results in increased expression of SREBF2 mRNA] more ... CTD PMID:30825513 caffeine increases expression EXP 6480464 Caffeine results in increased expression of SREBF2 mRNA, Caffeine results in increased expression of SREBF2 protein CTD PMID:30825513 caffeine increases expression ISO RGD:1307751 6480464 Caffeine results in increased expression of SREBF2 mRNA, Caffeine results in increased expression of SREBF2 protein CTD PMID:30825513 carbamazepine decreases expression EXP 6480464 Carbamazepine results in decreased expression of SREBF2 mRNA CTD PMID:21123845 carbon nanotube increases expression ISO RGD:730973 6480464 Nanotubes more ... CTD PMID:25554681 carbon nanotube increases expression EXP 6480464 Nanotubes, Carbon results in increased expression of SREBF2 mRNA CTD PMID:31047983 CGP 52608 multiple interactions EXP 6480464 CGP 52608 promotes the reaction [RORA protein binds to SREBF2 gene] CTD PMID:28238834 CGS-21680 multiple interactions EXP 6480464 2-(4-(2-carboxyethyl)phenethylamino)-5'-N-ethylcarboxamidoadenosine inhibits the reaction [Caffeine results in increased expression of SREBF2 mRNA] CTD PMID:30825513 chlorpromazine multiple interactions EXP 6480464 Chlorpromazine results in increased cleavage of and results in increased activity of SREBF2 protein CTD PMID:17052361 cholesterol multiple interactions EXP 6480464 [25-hydroxycholesterol co-treated with Cholesterol] results in decreased cleavage of SREBF2 protein more ... CTD PMID:16946405 more ... cholesterol multiple interactions ISO RGD:1307751 6480464 [Cholesterol deficiency co-treated with Lovastatin] results in increased activity of SREBF2 protein, Cholesterol inhibits the reaction [[Cholesterol deficiency co-treated with Lovastatin] results in increased activity of SREBF2 protein] CTD PMID:20578043 cholesterol increases abundance EXP 6480464 SREBF2 protein results in increased abundance of Cholesterol CTD PMID:33677747 choline multiple interactions ISO RGD:730973 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with RXRA gene mutant form] results in increased expression of SREBF2 mRNA CTD PMID:18952117 chromium(6+) affects expression ISO RGD:730973 6480464 chromium hexavalent ion affects the expression of SREBF2 mRNA CTD PMID:28472532 cisplatin multiple interactions EXP 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of SREBF2 mRNA CTD PMID:27392435 citalopram multiple interactions EXP 6480464 Citalopram results in increased cleavage of and results in increased activity of SREBF2 protein CTD PMID:16324787 clofibrate decreases expression ISO RGD:1307751 6480464 Clofibrate results in decreased expression of SREBF2 mRNA, Clofibrate results in decreased expression of SREBF2 protein CTD PMID:17126302 clomipramine multiple interactions EXP 6480464 Clomipramine results in increased cleavage of and results in increased activity of SREBF2 protein CTD PMID:16324787 clozapine multiple interactions EXP 6480464 Clozapine inhibits the reaction [25-hydroxycholesterol results in decreased activity of SREBF2 protein], Clozapine results in increased cleavage of and results in increased activity of SREBF2 protein CTD PMID:17052361 clozapine increases expression EXP 6480464 Clozapine results in increased expression of SREBF2 mRNA CTD PMID:17052361 cobalt dichloride decreases expression EXP 6480464 cobaltous chloride results in decreased expression of SREBF2 mRNA CTD PMID:19320972 colforsin daropate hydrochloride multiple interactions EXP 6480464 Colforsin inhibits the reaction [Caffeine results in increased expression of SREBF2 mRNA] CTD PMID:30825513 copper(II) chloride decreases expression EXP 6480464 cupric chloride results in decreased expression of SREBF2 mRNA CTD PMID:34921933 crizotinib increases expression EXP 6480464 crizotinib results in increased expression of SREBF2 mRNA CTD PMID:23707608 CU-O LINKAGE increases expression EXP 6480464 cupric oxide results in increased expression of SREBF2 mRNA CTD PMID:22077320 curcumin affects expression ISO RGD:730973 6480464 Curcumin affects the expression of SREBF2 mRNA, Curcumin affects the expression of SREBF2 protein CTD PMID:27208389 curcumin decreases expression ISO RGD:1307751 6480464 Curcumin results in decreased expression of SREBF2 mRNA CTD PMID:27208389 cyclosporin A increases expression EXP 6480464 Cyclosporine results in increased expression of SREBF2 mRNA CTD PMID:25562108 D-glucose increases expression EXP 6480464 Glucose results in increased expression of SREBF2 protein CTD PMID:23647015 D-glucose multiple interactions EXP 6480464 Allopurinol inhibits the reaction [Glucose results in increased expression of SREBF2 protein] more ... CTD PMID:23647015 D-glucose increases expression ISO RGD:1307751 6480464 Glucose results in increased expression of SREBF2 protein CTD PMID:23647015 D-glucose multiple interactions ISO RGD:1307751 6480464 Allopurinol inhibits the reaction [Glucose results in increased expression of SREBF2 protein] more ... CTD PMID:23647015 DDT increases methylation ISO RGD:1307751 6480464 DDT results in increased methylation of SREBF2 gene CTD PMID:30207508 dibutyl phthalate decreases expression ISO RGD:1307751 6480464 Dibutyl Phthalate results in decreased expression of SREBF2 protein CTD PMID:21266533 diclofenac increases expression ISO RGD:730973 6480464 Diclofenac results in increased expression of SREBF2 mRNA CTD PMID:26934552 dicrotophos increases expression EXP 6480464 dicrotophos results in increased expression of SREBF2 mRNA CTD PMID:28302478 dimethylarsinic acid multiple interactions ISO RGD:730973 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of SREBF2 mRNA CTD PMID:34876320 dinophysistoxin 1 decreases expression EXP 6480464 dinophysistoxin 1 results in decreased expression of SREBF2 mRNA CTD PMID:28939011 dorsomorphin multiple interactions EXP 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 , PMID:29499335 dorsomorphin increases cleavage ISO RGD:730973 6480464 dorsomorphin results in increased cleavage of SREBF2 protein CTD PMID:29499335 dorsomorphin multiple interactions ISO RGD:730973 6480464 dorsomorphin promotes the reaction [Hydrogen Peroxide results in increased cleavage of SREBF2 protein] CTD PMID:29499335 doxorubicin decreases expression EXP 6480464 Doxorubicin results in decreased expression of SREBF2 mRNA CTD PMID:29803840 elemental selenium increases expression EXP 6480464 Selenium results in increased expression of SREBF2 mRNA CTD PMID:19244175 ethanol affects splicing ISO RGD:730973 6480464 Ethanol affects the splicing of SREBF2 mRNA CTD PMID:30319688 ethanol multiple interactions ISO RGD:730973 6480464 withaferin A inhibits the reaction [Ethanol results in increased expression of SREBF2 mRNA] CTD PMID:34995708 ethanol increases expression ISO RGD:730973 6480464 Ethanol results in increased expression of SREBF2 mRNA CTD PMID:30319688 , PMID:34995708 ezetimibe decreases expression EXP 6480464 Ezetimibe results in decreased expression of SREBF2 mRNA CTD PMID:16177187 fenarimol increases expression ISO RGD:1307751 6480464 fenarimol results in increased expression of SREBF2 mRNA CTD PMID:28970091 fenvalerate increases expression ISO RGD:1307751 6480464 fenvalerate results in increased expression of SREBF2 mRNA CTD PMID:30307764 fisetin increases expression EXP 6480464 fisetin results in increased expression of SREBF2 protein alternative form CTD PMID:23524313 Ganoderic acid A multiple interactions ISO RGD:730973 6480464 [Dietary Fats co-treated with ganoderic acid A] affects the expression of SREBF2 mRNA, [Dietary Fats co-treated with ganoderic acid A] affects the expression of SREBF2 protein CTD PMID:29852127 Ganoderic acid A decreases expression EXP 6480464 ganoderic acid A results in decreased expression of SREBF2 mRNA, ganoderic acid A results in decreased expression of SREBF2 protein CTD PMID:29852127 geraniol increases expression EXP 6480464 geraniol results in increased expression of SREBF2 mRNA CTD PMID:23668785 glafenine increases expression ISO RGD:1307751 6480464 Glafenine results in increased expression of SREBF2 mRNA CTD PMID:24136188 glucose increases expression EXP 6480464 Glucose results in increased expression of SREBF2 protein CTD PMID:23647015 glucose multiple interactions EXP 6480464 Allopurinol inhibits the reaction [Glucose results in increased expression of SREBF2 protein] more ... CTD PMID:23647015 glucose increases expression ISO RGD:1307751 6480464 Glucose results in increased expression of SREBF2 protein CTD PMID:23647015 glucose multiple interactions ISO RGD:1307751 6480464 Allopurinol inhibits the reaction [Glucose results in increased expression of SREBF2 protein] more ... CTD PMID:23647015 glyphosate increases expression ISO RGD:730973 6480464 glyphosate results in increased expression of SREBF2 mRNA CTD PMID:31374489 haloperidol multiple interactions EXP 6480464 Haloperidol results in increased cleavage of and results in increased activity of SREBF2 protein CTD PMID:17052361 herbacetin multiple interactions ISO RGD:730973 6480464 herbacetin inhibits the reaction [Dietary Fats results in increased expression of SREBF2 mRNA] CTD PMID:29653099 hydrogen peroxide multiple interactions EXP 6480464 [isoquercitrin co-treated with Hydrogen Peroxide] results in increased cleavage of and results in increased activity of SREBF2 protein more ... CTD PMID:18032389 hydrogen peroxide increases cleavage ISO RGD:730973 6480464 Hydrogen Peroxide results in increased cleavage of SREBF2 protein CTD PMID:29499335 hydrogen peroxide multiple interactions ISO RGD:730973 6480464 Buthionine Sulfoximine inhibits the reaction [Metformin inhibits the reaction [Hydrogen Peroxide results in increased cleavage of SREBF2 protein]] more ... CTD PMID:29499335 imipramine multiple interactions EXP 6480464 Imipramine results in increased cleavage of and results in increased activity of SREBF2 protein CTD PMID:16324787 ketoconazole increases expression ISO RGD:1307751 6480464 Ketoconazole results in increased expression of SREBF2 mRNA CTD PMID:28263823 L-ascorbic acid increases expression ISO RGD:730973 6480464 Ascorbic Acid results in increased expression of SREBF2 mRNA CTD PMID:32913121 L-ascorbic acid multiple interactions EXP 6480464 SREBF2 protein affects the reaction [Ascorbic Acid results in increased expression of LDLR mRNA], SREBF2 protein affects the reaction [Ascorbic Acid results in increased expression of LDLR protein] CTD PMID:32913121 L-ascorbic acid decreases metabolic processing EXP 6480464 Ascorbic Acid results in decreased metabolism of SREBF2 protein CTD PMID:32913121 L-methionine multiple interactions ISO RGD:730973 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with RXRA gene mutant form] results in increased expression of SREBF2 mRNA CTD PMID:18952117 lead diacetate increases expression ISO RGD:1307751 6480464 lead acetate results in increased expression of SREBF2 mRNA, lead acetate results in increased expression of SREBF2 protein CTD PMID:29908845 lead nitrate increases expression ISO RGD:1307751 6480464 lead nitrate results in increased expression of SREBF2 mRNA CTD PMID:15475176 , PMID:16705668 linalool multiple interactions EXP 6480464 linalool inhibits the reaction [SREBF2 protein binds to HMGCR promoter] CTD PMID:21944868 linalool decreases expression EXP 6480464 linalool results in decreased expression of SREBF2 mRNA, linalool results in decreased expression of SREBF2 protein CTD PMID:21944868 linalool decreases expression ISO RGD:730973 6480464 linalool results in decreased expression of SREBF2 mRNA, linalool results in decreased expression of SREBF2 protein CTD PMID:21944868 lipopolysaccharide increases expression ISO RGD:1307751 6480464 Lipopolysaccharides results in increased expression of SREBF2 protein CTD PMID:33677747 lipopolysaccharide multiple interactions EXP 6480464 ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Lipopolysaccharides results in increased expression of SREBF2 protein] more ... CTD PMID:33677747 lipopolysaccharide multiple interactions ISO RGD:1307751 6480464 ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Lipopolysaccharides results in increased expression of SREBF2 protein] more ... CTD PMID:33677747 lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of SREBF2 mRNA CTD PMID:33677747 lovastatin increases localization EXP 6480464 Lovastatin results in increased localization of SREBF2 protein CTD PMID:11728391 lovastatin multiple interactions ISO RGD:1307751 6480464 [Cholesterol deficiency co-treated with Lovastatin] results in increased activity of SREBF2 protein, Cholesterol inhibits the reaction [[Cholesterol deficiency co-treated with Lovastatin] results in increased activity of SREBF2 protein] CTD PMID:20578043 lovastatin multiple interactions ISO RGD:730973 6480464 [Dietary Fats co-treated with Lovastatin] affects the expression of SREBF2 mRNA CTD PMID:29852127 mercury dichloride decreases expression EXP 6480464 Mercuric Chloride results in decreased expression of SREBF2 mRNA CTD PMID:27188386 metformin multiple interactions ISO RGD:730973 6480464 Buthionine Sulfoximine inhibits the reaction [Metformin inhibits the reaction [Hydrogen Peroxide results in increased cleavage of SREBF2 protein]] more ... CTD PMID:29499335 metformin multiple interactions EXP 6480464 Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased cleavage of SREBF2 protein] CTD PMID:29499335 methylarsonic acid multiple interactions ISO RGD:730973 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of SREBF2 mRNA CTD PMID:34876320 mevastatin increases expression ISO RGD:1307751 6480464 mevastatin results in increased expression of SREBF2 protein CTD PMID:17526932 mevastatin increases cleavage ISO RGD:730973 6480464 mevastatin results in increased cleavage of SREBF2 protein CTD PMID:16330322 microcystin-LR increases expression ISO RGD:730973 6480464 cyanoginosin LR results in increased expression of SREBF2 mRNA CTD PMID:25497113 mono(2-ethylhexyl) phthalate increases expression EXP 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of SREBF2 mRNA CTD PMID:23118965 Monobutylphthalate multiple interactions ISO RGD:730973 6480464 monobutyl phthalate promotes the reaction [SREBF2 protein binds to STARD4 promoter], SREBF2 protein affects the reaction [monobutyl phthalate results in increased abundance of Cholesterol Esters] CTD PMID:31705742 monocrotophos increases expression ISO RGD:1307751 6480464 Monocrotophos results in increased expression of SREBF2 mRNA CTD PMID:32267039 monosodium L-glutamate increases expression ISO RGD:730973 6480464 Sodium Glutamate results in increased expression of SREBF2 mRNA CTD PMID:20111022 monosodium L-glutamate multiple interactions ISO RGD:730973 6480464 [Fats more ... CTD PMID:20111022 , PMID:23783067 monosodium L-glutamate decreases expression ISO RGD:730973 6480464 Sodium Glutamate results in decreased expression of SREBF2 mRNA CTD PMID:22078008 myricetin multiple interactions ISO RGD:1307751 6480464 myricetin inhibits the reaction [[Streptozocin co-treated with Cadmium] results in increased expression of SREBF2 protein] CTD PMID:25240712 N,N-diethyl-m-toluamide multiple interactions ISO RGD:1307751 6480464 [Permethrin co-treated with DEET] results in decreased methylation of SREBF2 gene CTD PMID:33148267 N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions EXP 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [CGA protein results in increased cleavage of SREBF2 protein] CTD PMID:26125464 obeticholic acid multiple interactions ISO RGD:730973 6480464 obeticholic acid inhibits the reaction [Dietary Fats results in increased expression of SREBF2 mRNA] CTD PMID:26655953 obeticholic acid decreases expression EXP 6480464 obeticholic acid results in decreased expression of SREBF2 mRNA CTD PMID:27939613 okadaic acid decreases expression EXP 6480464 Okadaic Acid results in decreased expression of SREBF2 mRNA CTD PMID:28939011 olanzapine multiple interactions EXP 6480464 olanzapine results in increased cleavage of and results in increased activity of SREBF2 protein CTD PMID:17052361 olanzapine multiple interactions ISO RGD:1307751 6480464 [olanzapine co-treated with 1-(carboxymethylthio)tetradecane] results in decreased expression of SREBF2 mRNA CTD PMID:23226405 ozone multiple interactions ISO RGD:1307751 6480464 Ozone inhibits the reaction [Fish Oils results in increased expression of SREBF2 mRNA] CTD PMID:33217375 ozone multiple interactions EXP 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of SREBF2 mRNA more ... CTD PMID:32699268 ozone decreases expression ISO RGD:1307751 6480464 Ozone results in decreased expression of SREBF2 mRNA CTD PMID:25838073 p-chloromercuribenzoic acid decreases expression EXP 6480464 p-Chloromercuribenzoic Acid results in decreased expression of SREBF2 mRNA CTD PMID:26272509 p-chloromercuribenzoic acid multiple interactions EXP 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SREBF2 mRNA CTD PMID:27188386 p-menthan-3-ol decreases expression EXP 6480464 Menthol results in decreased expression of SREBF2 mRNA CTD PMID:26760959 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of SREBF2 mRNA CTD PMID:29067470 paracetamol decreases expression ISO RGD:1307751 6480464 Acetaminophen results in decreased expression of SREBF2 mRNA CTD PMID:32479839 , PMID:33387578 perfluorooctane-1-sulfonic acid decreases expression ISO RGD:730973 6480464 perfluorooctane sulfonic acid results in decreased expression of SREBF2 mRNA CTD PMID:20936131 perfluorooctane-1-sulfonic acid decreases expression EXP 6480464 perfluorooctane sulfonic acid results in decreased expression of SREBF2 mRNA CTD PMID:32253466 perfluorooctanoic acid decreases expression ISO RGD:730973 6480464 perfluorooctanoic acid results in decreased expression of SREBF2 mRNA CTD PMID:20936131 more ... perfluorooctanoic acid decreases expression EXP 6480464 perfluorooctanoic acid results in decreased expression of SREBF2 mRNA CTD PMID:32253466 perfluorooctanoic acid increases expression ISO RGD:730973 6480464 perfluorooctanoic acid results in increased expression of SREBF2 mRNA CTD PMID:30711707 perfluorooctanoic acid increases cleavage ISO RGD:730973 6480464 perfluorooctanoic acid results in increased cleavage of SREBF2 protein CTD PMID:25092180 permethrin multiple interactions ISO RGD:1307751 6480464 [Permethrin co-treated with DEET] results in decreased methylation of SREBF2 gene CTD PMID:33148267 phenylpropanolamine multiple interactions EXP 6480464 Phenylpropanolamine results in increased cleavage of and results in increased activity of SREBF2 protein CTD PMID:27756839 phorbol 13-acetate 12-myristate multiple interactions EXP 6480464 dorsomorphin promotes the reaction [Tetradecanoylphorbol Acetate results in increased cleavage of SREBF2 protein], Metformin inhibits the reaction [Tetradecanoylphorbol Acetate results in increased cleavage of SREBF2 protein] CTD PMID:29499335 phorbol 13-acetate 12-myristate increases cleavage EXP 6480464 Tetradecanoylphorbol Acetate results in increased cleavage of SREBF2 protein CTD PMID:29499335 pirinixic acid decreases expression ISO RGD:1307751 6480464 pirinixic acid results in decreased expression of SREBF2 mRNA, pirinixic acid results in decreased expression of SREBF2 protein CTD PMID:17126302 propiconazole increases expression ISO RGD:1307751 6480464 propiconazole results in increased expression of SREBF2 mRNA CTD PMID:28970091 quercetin multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Quercetin results in increased metabolism of and affects the localization of SREBF2 protein] more ... CTD PMID:20728021 more ... quercetin multiple interactions ISO RGD:1307751 6480464 Quercetin inhibits the reaction [Glucose results in increased expression of SREBF2 protein] more ... CTD PMID:23647015 quercetin 3-O-beta-D-glucofuranoside multiple interactions EXP 6480464 [isoquercitrin co-treated with Hydrogen Peroxide] results in increased cleavage of and results in increased activity of SREBF2 protein more ... CTD PMID:18032389 quercetin 3-O-beta-D-glucopyranoside multiple interactions EXP 6480464 [isoquercitrin co-treated with Hydrogen Peroxide] results in increased cleavage of and results in increased activity of SREBF2 protein more ... CTD PMID:18032389 rac-lactic acid increases expression EXP 6480464 Lactic Acid results in increased expression of SREBF2 mRNA CTD PMID:30851411 resveratrol increases expression EXP 6480464 resveratrol results in increased expression of SREBF2 protein modified form CTD PMID:22153697 resveratrol multiple interactions EXP 6480464 25-hydroxycholesterol inhibits the reaction [[Resveratrol results in increased activity of and results in increased cleavage of SREBF2 protein] which results in increased expression of LDLR mRNA] more ... CTD PMID:22153697 , PMID:30825513 rotenone increases expression ISO RGD:1307751 6480464 Rotenone results in increased expression of SREBF2 mRNA CTD PMID:28374803 S-butyl-DL-homocysteine (S,R)-sulfoximine multiple interactions ISO RGD:730973 6480464 Buthionine Sulfoximine inhibits the reaction [Metformin inhibits the reaction [Hydrogen Peroxide results in increased cleavage of SREBF2 protein]], Buthionine Sulfoximine promotes the reaction [Hydrogen Peroxide results in increased cleavage of SREBF2 protein] CTD PMID:29499335 SB 431542 multiple interactions EXP 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SREBF2 mRNA CTD PMID:27188386 selenium atom increases expression EXP 6480464 Selenium results in increased expression of SREBF2 mRNA CTD PMID:19244175 silicon dioxide decreases expression EXP 6480464 Silicon Dioxide analog results in decreased expression of SREBF2 mRNA CTD PMID:25895662 simvastatin multiple interactions EXP 6480464 Mevalonic Acid inhibits the reaction [Simvastatin promotes the reaction [SREBF2 protein binds to PON1 promoter]], Simvastatin promotes the reaction [SREBF2 protein binds to PON1 promoter] CTD PMID:14500290 simvastatin increases expression ISO RGD:1307751 6480464 Simvastatin results in increased expression of SREBF2 mRNA CTD PMID:12056585 simvastatin multiple interactions ISO RGD:1307751 6480464 Mevalonic Acid inhibits the reaction [Simvastatin results in increased expression of SREBF2 mRNA], Simvastatin results in increased activity of and results in increased localization of SREBF2 protein CTD PMID:12056585 simvastatin increases expression EXP 6480464 Simvastatin results in increased expression of SREBF2 protein modified form CTD PMID:20018177 sodium arsenate increases expression ISO RGD:730973 6480464 sodium arsenate results in increased expression of SREBF2 mRNA CTD PMID:30953684 sodium arsenate multiple interactions ISO RGD:730973 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of SREBF2 mRNA CTD PMID:34876320 sodium arsenite multiple interactions ISO RGD:730973 6480464 [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of SREBF2 mRNA CTD PMID:34876320 Soman decreases expression ISO RGD:1307751 6480464 Soman results in decreased expression of SREBF2 mRNA CTD PMID:19281266 streptozocin increases expression ISO RGD:1307751 6480464 Streptozocin results in increased expression of SREBF2 mRNA, Streptozocin results in increased expression of SREBF2 protein CTD PMID:23647015 streptozocin increases expression ISO RGD:730973 6480464 Streptozocin results in increased expression of SREBF2 mRNA, Streptozocin results in increased expression of SREBF2 protein CTD PMID:29420703 , PMID:34896238 streptozocin multiple interactions ISO RGD:730973 6480464 Acrylamide inhibits the reaction [Streptozocin results in increased expression of SREBF2 mRNA], fatostatin inhibits the reaction [Streptozocin results in increased expression of SREBF2 protein] CTD PMID:29420703 , PMID:34896238 streptozocin multiple interactions ISO RGD:1307751 6480464 [Streptozocin co-treated with Cadmium] results in increased expression of SREBF2 protein more ... CTD PMID:23647015 , PMID:25240712 sulindac sulfide decreases expression EXP 6480464 sulindac sulfide results in decreased expression of SREBF2 mRNA CTD PMID:16184548 sunitinib increases expression EXP 6480464 Sunitinib results in increased expression of SREBF2 mRNA CTD PMID:31533062 testosterone increases expression ISO RGD:730973 6480464 Testosterone results in increased expression of SREBF2 mRNA CTD PMID:16579987 thioacetamide increases expression ISO RGD:1307751 6480464 Thioacetamide results in increased expression of SREBF2 protein CTD PMID:33677747 thioacetamide decreases expression ISO RGD:1307751 6480464 Thioacetamide results in decreased expression of SREBF2 mRNA CTD PMID:34492290 tributyl phosphate increases expression EXP 6480464 tributyl phosphate results in increased expression of SREBF2 mRNA CTD PMID:30966736 trimellitic anhydride increases expression ISO RGD:730973 6480464 trimellitic anhydride results in increased expression of SREBF2 mRNA CTD PMID:19042947 triphenyl phosphate increases expression EXP 6480464 triphenyl phosphate results in increased expression of SREBF2 mRNA CTD PMID:30966736 troglitazone multiple interactions EXP 6480464 [[troglitazone binds to and results in increased activity of PPARG protein] which results in decreased expression of SREBF2 protein] which results in decreased abundance of Cholesterol more ... CTD PMID:16946405 tungsten decreases expression ISO RGD:730973 6480464 Tungsten results in decreased expression of SREBF2 mRNA CTD PMID:30912803 tunicamycin decreases expression EXP 6480464 Tunicamycin results in decreased expression of SREBF2 mRNA CTD PMID:22378314 valdecoxib increases expression ISO RGD:1307751 6480464 valdecoxib results in increased expression of SREBF2 mRNA CTD PMID:24136188 valproic acid increases methylation EXP 6480464 Valproic Acid results in increased methylation of SREBF2 gene CTD PMID:29154799 valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of SREBF2 mRNA CTD PMID:23179753 , PMID:27188386 valproic acid affects expression ISO RGD:730973 6480464 Valproic Acid affects the expression of SREBF2 mRNA CTD PMID:17963808 vinclozolin increases expression ISO RGD:1307751 6480464 vinclozolin results in increased expression of SREBF2 mRNA CTD PMID:22570695 vinclozolin decreases expression ISO RGD:1307751 6480464 vinclozolin results in decreased expression of SREBF2 mRNA CTD PMID:23034163 vorinostat decreases expression EXP 6480464 vorinostat results in decreased expression of SREBF2 mRNA CTD PMID:27188386 withaferin A multiple interactions ISO RGD:730973 6480464 withaferin A inhibits the reaction [Ethanol results in increased expression of SREBF2 mRNA] CTD PMID:34995708
