SLC3A2 (solute carrier family 3 member 2) - Rat Genome Database

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Gene: SLC3A2 (solute carrier family 3 member 2) Homo sapiens
Analyze
Symbol: SLC3A2
Name: solute carrier family 3 member 2
RGD ID: 735716
HGNC Page HGNC
Description: Exhibits amino acid transmembrane transporter activity and double-stranded RNA binding activity. Involved in carboxylic acid transport and response to exogenous dsRNA. Localizes to several cellular components, including amino acid transport complex; apical plasma membrane; and basolateral plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 4F2; 4F2 cell-surface antigen heavy chain; 4F2 heavy chain antigen; 4F2HC; 4T2HC; antigen defined by monoclonal antibody 4F2, heavy chain; antigen identified by monoclonal antibodies 4F2, TRA1.10, TROP4, and T43; CD98; CD98 heavy chain; CD98HC; heavy chain; lymphocyte activation antigen 4F2 large subunit; MDU1; monoclonal antibody 44D7; NACAE; solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2; solute carrier family 3 (amino acid transporter heavy chain), member 2; solute carrier family 3, member 2
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1162,856,004 - 62,888,880 (+)EnsemblGRCh38hg38GRCh38
GRCh381162,856,109 - 62,888,860 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371162,623,581 - 62,656,332 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361162,380,094 - 62,412,929 (+)NCBINCBI36hg18NCBI36
Build 341162,380,149 - 62,412,840NCBI
Celera1159,946,914 - 59,979,926 (+)NCBI
Cytogenetic Map11q12.3NCBI
HuRef1158,952,521 - 58,985,401 (+)NCBIHuRef
CHM1_11162,506,504 - 62,539,366 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP,ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
2-butoxyethanol  (ISO)
2-tert-butylhydroquinone  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3-chloropropane-1,2-diol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4-amino-2,6-dinitrotoluene  (ISO)
4-hydroxyphenyl retinamide  (EXP)
5-aza-2'-deoxycytidine  (EXP)
5-fluorouracil  (EXP)
8-Br-cAMP  (EXP)
acetamide  (ISO)
acrolein  (EXP)
acrylamide  (EXP,ISO)
actinomycin D  (EXP)
afimoxifene  (EXP)
aflatoxin B1  (EXP,ISO)
alpha-pinene  (EXP)
amiodarone  (EXP)
aristolochic acid  (EXP)
Aroclor 1254  (ISO)
arsane  (EXP)
arsenic atom  (EXP)
arsenite(3-)  (EXP)
arsenous acid  (EXP)
azathioprine  (EXP)
beauvericin  (EXP)
benzo[a]pyrene  (EXP,ISO)
beta-naphthoflavone  (EXP)
bicalutamide  (EXP)
bilirubin IXalpha  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
boron nitride  (EXP)
bosentan  (EXP)
butan-1-ol  (EXP)
cadmium atom  (EXP)
cadmium dichloride  (EXP,ISO)
cannabidiol  (ISO)
carbamazepine  (EXP)
carbon nanotube  (ISO)
carmustine  (ISO)
celastrol  (EXP)
chloroacetaldehyde  (EXP)
chlorpromazine  (ISO)
choline  (ISO)
chrysene  (EXP)
cidofovir anhydrous  (EXP)
cisplatin  (EXP)
clodronic acid  (EXP)
clofibrate  (ISO)
clofibric acid  (ISO)
cobalt dichloride  (EXP,ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (EXP)
crocidolite asbestos  (EXP)
curcumin  (EXP,ISO)
cycloheximide  (EXP)
cyclophosphamide  (EXP)
cyclosporin A  (EXP,ISO)
dexamethasone  (EXP)
diarsenic trioxide  (EXP)
dibutyl phthalate  (ISO)
diethyl maleate  (EXP)
diethylstilbestrol  (EXP)
dioxygen  (EXP,ISO)
diuron  (ISO)
dorsomorphin  (EXP)
elemental selenium  (EXP)
endosulfan  (ISO)
enniatin  (EXP)
entinostat  (EXP)
enzyme inhibitor  (EXP)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (EXP)
fenofibrate  (EXP,ISO)
fipronil  (ISO)
fluoranthene  (ISO)
flutamide  (ISO)
folic acid  (ISO)
formaldehyde  (EXP)
gamma-hexachlorocyclohexane  (EXP)
gamma-linolenic acid  (EXP)
gedunin  (EXP)
genistein  (EXP)
glutathione  (EXP)
Heptachlor epoxide  (ISO)
hydralazine  (EXP)
hydrogen chloride  (ISO)
hydrogen peroxide  (EXP)
ibuprofen  (EXP)
ifosfamide  (EXP)
indometacin  (EXP,ISO)
ionomycin  (EXP)
L-cystine  (EXP,ISO)
L-methionine  (ISO)
lamivudine  (EXP)
lead diacetate  (ISO)
leflunomide  (EXP,ISO)
lithium chloride  (EXP)
mercaptoethanol  (EXP)
mercury dibromide  (EXP)
mercury dichloride  (EXP)
metformin  (ISO)
methapyrilene  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (EXP)
methylmercury chloride  (EXP)
methylparaben  (EXP)
motexafin gadolinium  (EXP)
N-methyl-4-phenylpyridinium  (EXP,ISO)
N-nitrosodiethylamine  (ISO)
N-Nitrosopyrrolidine  (EXP)
nefazodone  (ISO)
nimesulide  (ISO)
O-methyleugenol  (EXP)
ozone  (EXP)
p-chloromercuribenzoic acid  (EXP)
paracetamol  (EXP,ISO)
paraquat  (ISO)
pentachlorophenol  (ISO)
perfluorononanoic acid  (EXP)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (EXP,ISO)
phenylmercury acetate  (EXP)
phorbol 13-acetate 12-myristate  (EXP)
phorone  (ISO)
phosgene  (ISO)
phytoestrogen  (EXP)
piperonyl butoxide  (ISO)
pirinixic acid  (ISO)
piroxicam  (EXP)
pregnenolone 16alpha-carbonitrile  (ISO)
pyrrolidine dithiocarbamate  (EXP)
quercetin  (EXP)
raloxifene  (EXP)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (EXP)
SB 431542  (EXP)
selenium atom  (EXP)
serpentine asbestos  (EXP)
sevoflurane  (ISO)
silicon dioxide  (EXP)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenite  (EXP)
sodium dichromate  (ISO)
sodium fluoride  (ISO)
sulfasalazine  (ISO)
sulindac  (EXP)
sulindac sulfide  (EXP)
sunitinib  (EXP)
tamoxifen  (EXP)
tetrachloroethene  (ISO)
tetrachloromethane  (ISO)
tetraphene  (EXP)
thapsigargin  (EXP)
thioacetamide  (ISO)
tioguanine  (ISO)
titanium dioxide  (ISO)
triadimefon  (ISO)
trichloroethene  (ISO)
triptonide  (ISO)
troglitazone  (EXP,ISO)
tunicamycin  (EXP)
valdecoxib  (ISO)
valproic acid  (EXP)
vinclozolin  (ISO)
zearalenone  (EXP)
zidovudine  (EXP)
zinc acetate  (EXP)
zinc atom  (EXP)
zinc(0)  (EXP)
zoledronic acid  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

Additional References at PubMed
PMID:1358795   PMID:2416754   PMID:3036867   PMID:3265470   PMID:3265471   PMID:3476959   PMID:3480538   PMID:3782435   PMID:6177771   PMID:6187076   PMID:6190235   PMID:7204970  
PMID:7561057   PMID:8125298   PMID:8619474   PMID:8922468   PMID:8938448   PMID:9110174   PMID:9403839   PMID:9751058   PMID:9829974   PMID:9878049   PMID:10391915   PMID:10506149  
PMID:10574970   PMID:10631289   PMID:10673541   PMID:10863037   PMID:10903140   PMID:11311135   PMID:11406111   PMID:11435306   PMID:11507094   PMID:11696247   PMID:11742812   PMID:11749697  
PMID:11840567   PMID:12181350   PMID:12235164   PMID:12270127   PMID:12477932   PMID:12493773   PMID:12531285   PMID:12716892   PMID:12740424   PMID:12754519   PMID:12925876   PMID:14527684  
PMID:14702039   PMID:15146197   PMID:15178563   PMID:15231747   PMID:15274339   PMID:15458438   PMID:15485886   PMID:15489334   PMID:15556631   PMID:15589117   PMID:15625115   PMID:15713750  
PMID:15782160   PMID:15901826   PMID:16335952   PMID:16344560   PMID:16712791   PMID:16785209   PMID:16799092   PMID:17023546   PMID:17081065   PMID:17081983   PMID:17197568   PMID:17353931  
PMID:17451431   PMID:17558306   PMID:17611393   PMID:17724034   PMID:18032696   PMID:18054915   PMID:18195088   PMID:18660501   PMID:18813831   PMID:19018776   PMID:19056867   PMID:19065266  
PMID:19171406   PMID:19199708   PMID:19562367   PMID:19581412   PMID:19738201   PMID:19777189   PMID:19808856   PMID:19913121   PMID:19922591   PMID:19946888   PMID:20091333   PMID:20374249  
PMID:20458337   PMID:20628086   PMID:20811665   PMID:21145461   PMID:21266579   PMID:21270293   PMID:21282044   PMID:21352957   PMID:21486766   PMID:21670318   PMID:21750865   PMID:22077314  
PMID:22234250   PMID:22291182   PMID:22304920   PMID:22360420   PMID:22499670   PMID:22658674   PMID:22678362   PMID:22810586   PMID:22939629   PMID:23137377   PMID:23272174   PMID:23297381  
PMID:23376485   PMID:23383273   PMID:23438482   PMID:23533145   PMID:23651923   PMID:23940088   PMID:24189400   PMID:24337577   PMID:24359579   PMID:24484217   PMID:24516142   PMID:24639526  
PMID:24711643   PMID:24755837   PMID:24782339   PMID:24797263   PMID:25041835   PMID:25063885   PMID:25084765   PMID:25299125   PMID:25324306   PMID:25437307   PMID:25468996   PMID:25505297  
PMID:25631074   PMID:25701737   PMID:25921289   PMID:25963833   PMID:25995262   PMID:25998567   PMID:26172215   PMID:26344197   PMID:26439863   PMID:26493331   PMID:26496610   PMID:26508657  
PMID:26514267   PMID:26540405   PMID:26621329   PMID:26638075   PMID:26641092   PMID:26752685   PMID:26972000   PMID:27025967   PMID:27342126   PMID:27377895   PMID:27437069   PMID:27462432  
PMID:27542412   PMID:27591049   PMID:27626312   PMID:27834933   PMID:27880917   PMID:28052681   PMID:28112518   PMID:28179310   PMID:28298427   PMID:28302793   PMID:28320871   PMID:28350098  
PMID:28378594   PMID:28515276   PMID:28675297   PMID:28685749   PMID:28692057   PMID:28712289   PMID:28902428   PMID:29053956   PMID:29117863   PMID:29128334   PMID:29180619   PMID:29229926  
PMID:29467282   PMID:29507755   PMID:29545595   PMID:29568061   PMID:29656893   PMID:29844126   PMID:29845934   PMID:29906411   PMID:29911972   PMID:29987050   PMID:30021884   PMID:30022168  
PMID:30024968   PMID:30194290   PMID:30300664   PMID:30341327   PMID:30442662   PMID:30442766   PMID:30455355   PMID:30462309   PMID:30470261   PMID:30575818   PMID:30619736   PMID:30639242  
PMID:30709928   PMID:30711629   PMID:30737378   PMID:30833792   PMID:30867591   PMID:30948266   PMID:30958588   PMID:31053148   PMID:31073040   PMID:31092450   PMID:31160781   PMID:31177093  
PMID:31182584   PMID:31253590   PMID:31276435   PMID:31282475   PMID:31300519   PMID:31343991   PMID:31527615   PMID:31536960   PMID:31575908   PMID:31586073   PMID:31678930   PMID:31701662  
PMID:31732153   PMID:31791063   PMID:31950832   PMID:31980649   PMID:31995728   PMID:32041737   PMID:32093034   PMID:32129710   PMID:32203420   PMID:32296183   PMID:32552912   PMID:32683582  
PMID:32788342   PMID:32993041   PMID:33066406   PMID:33144569   PMID:33184944   PMID:33957083  


Genomics

Comparative Map Data
SLC3A2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1162,856,004 - 62,888,880 (+)EnsemblGRCh38hg38GRCh38
GRCh381162,856,109 - 62,888,860 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371162,623,581 - 62,656,332 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361162,380,094 - 62,412,929 (+)NCBINCBI36hg18NCBI36
Build 341162,380,149 - 62,412,840NCBI
Celera1159,946,914 - 59,979,926 (+)NCBI
Cytogenetic Map11q12.3NCBI
HuRef1158,952,521 - 58,985,401 (+)NCBIHuRef
CHM1_11162,506,504 - 62,539,366 (+)NCBICHM1_1
Slc3a2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39198,684,246 - 8,700,733 (-)NCBIGRCm39mm39
GRCm39 Ensembl198,684,246 - 8,700,733 (-)Ensembl
GRCm38198,706,882 - 8,723,369 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl198,706,882 - 8,723,369 (-)EnsemblGRCm38mm10GRCm38
MGSCv37198,781,372 - 8,797,859 (-)NCBIGRCm37mm9NCBIm37
MGSCv36198,773,927 - 8,780,919 (-)NCBImm8
Celera198,465,148 - 8,481,790 (-)NCBICelera
Cytogenetic Map19ANCBI
cM Map195.44NCBI
Slc3a2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21205,604,468 - 205,618,931 (-)NCBI
Rnor_6.0 Ensembl1224,906,554 - 224,921,092 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01224,906,566 - 224,921,029 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01231,843,822 - 231,858,285 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41211,375,889 - 211,390,313 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11211,534,318 - 211,548,743 (-)NCBI
Celera1203,117,365 - 203,131,828 (-)NCBICelera
Cytogenetic Map1q43NCBI
Slc3a2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955599376,245 - 391,311 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955599376,133 - 391,434 (-)NCBIChiLan1.0ChiLan1.0
SLC3A2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11161,565,664 - 61,594,579 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1161,565,680 - 61,594,579 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01158,212,395 - 58,241,686 (+)NCBIMhudiblu_PPA_v0panPan3
SLC3A2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11853,810,468 - 53,819,021 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1853,810,398 - 53,819,021 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1852,416,355 - 52,424,896 (-)NCBI
ROS_Cfam_1.01854,862,432 - 54,870,971 (-)NCBI
UMICH_Zoey_3.11853,959,818 - 53,968,341 (-)NCBI
UNSW_CanFamBas_1.01853,533,954 - 53,542,486 (-)NCBI
UU_Cfam_GSD_1.01854,325,863 - 54,334,403 (-)NCBI
Slc3a2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494710,311,055 - 10,327,851 (-)NCBI
SpeTri2.0NW_004936581424,801 - 441,592 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC3A2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl28,892,089 - 8,919,072 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.128,892,071 - 8,919,070 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.228,245,279 - 8,273,049 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC3A2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1111,011,351 - 11,050,494 (-)NCBI
ChlSab1.1 Ensembl111,008,120 - 11,050,298 (-)Ensembl
Vero_WHO_p1.0NW_023666038108,363,791 - 108,393,242 (-)NCBI
Slc3a2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249261,301,866 - 1,314,598 (+)NCBI

Position Markers
RH98739  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371162,648,435 - 62,648,553UniSTSGRCh37
Build 361162,405,011 - 62,405,129RGDNCBI36
Celera1159,972,014 - 59,972,132RGD
Cytogenetic Map11q13UniSTS
HuRef1158,977,485 - 58,977,603UniSTS
GeneMap99-GB4 RH Map11230.64UniSTS
GDB:197851  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371162,656,114 - 62,656,295UniSTSGRCh37
Build 361162,412,690 - 62,412,871RGDNCBI36
Celera1159,979,687 - 59,979,868RGD
Cytogenetic Map11q13UniSTS
HuRef1158,985,160 - 58,985,341UniSTS
RH17582  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371162,656,128 - 62,656,283UniSTSGRCh37
Build 361162,412,704 - 62,412,859RGDNCBI36
Celera1159,979,701 - 59,979,856RGD
Cytogenetic Map11q13UniSTS
HuRef1158,985,174 - 58,985,329UniSTS
GeneMap99-GB4 RH Map11230.44UniSTS
NCBI RH Map11563.0UniSTS
G15889  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371162,656,178 - 62,656,327UniSTSGRCh37
Build 361162,412,754 - 62,412,903RGDNCBI36
Celera1159,979,751 - 59,979,900RGD
Cytogenetic Map11q13UniSTS
HuRef1158,985,224 - 58,985,373UniSTS
AF081279  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371162,622,913 - 62,623,447UniSTSGRCh37
Build 361162,379,489 - 62,380,023RGDNCBI36
Celera1159,946,309 - 59,946,843RGD
Cytogenetic Map11q12.3UniSTS
Cytogenetic Map11q13UniSTS
HuRef1158,951,950 - 58,952,484UniSTS
D11S1010  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371162,641,882 - 62,642,073UniSTSGRCh37
Build 361162,398,458 - 62,398,649RGDNCBI36
Celera1159,965,461 - 59,965,652RGD
Cytogenetic Map11q13UniSTS
MDU1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371162,647,363 - 62,648,211UniSTSGRCh37
Build 361162,403,939 - 62,404,787RGDNCBI36
Celera1159,970,942 - 59,971,790RGD
Cytogenetic Map11q13UniSTS
HuRef1158,976,413 - 58,977,261UniSTS
GeneMap99-GB4 RH Map11236.75UniSTS
NCBI RH Map11563.0UniSTS
SLC3A2_2672  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371162,655,778 - 62,656,415UniSTSGRCh37
Build 361162,412,354 - 62,412,991RGDNCBI36
Celera1159,979,351 - 59,979,988RGD
HuRef1158,984,824 - 58,985,461UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:5290
Count of miRNA genes:1105
Interacting mature miRNAs:1385
Transcripts:ENST00000338663, ENST00000377889, ENST00000377890, ENST00000377891, ENST00000377892, ENST00000457660, ENST00000535296, ENST00000535768, ENST00000536981, ENST00000537508, ENST00000537839, ENST00000538084, ENST00000538682, ENST00000539458, ENST00000539507, ENST00000539891, ENST00000541372, ENST00000541425, ENST00000541649, ENST00000542793, ENST00000542922, ENST00000544377, ENST00000546253, ENST00000546312
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High 1 4 1
Medium 2431 2772 1666 566 1926 408 4341 2009 3705 416 1444 1606 171 1204 2774 4
Low 6 216 57 58 25 57 16 187 26 3 12 4 4 1 14 2 2
Below cutoff 2 3 1 3 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001012662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001012664 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001013251 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_002394 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_037193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA594112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB018010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF055031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH001404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK025584 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK090758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK094620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK225304 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK304497 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK304685 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK308797 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK311592 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AP001160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AU143131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC001061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC003000 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE018712 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ128156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU556953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX362778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX443653 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA453972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB138799 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB151304 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN302816 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DC395235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ125482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J02769 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J02939 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J03569 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000338663   ⟹   ENSP00000340815
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,880,872 - 62,888,855 (+)Ensembl
RefSeq Acc Id: ENST00000377889   ⟹   ENSP00000367121
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,856,144 - 62,888,853 (+)Ensembl
RefSeq Acc Id: ENST00000377890   ⟹   ENSP00000367122
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,856,102 - 62,888,793 (+)Ensembl
RefSeq Acc Id: ENST00000377891   ⟹   ENSP00000367123
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,856,111 - 62,888,860 (+)Ensembl
RefSeq Acc Id: ENST00000457660
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,881,805 - 62,886,526 (+)Ensembl
RefSeq Acc Id: ENST00000535296   ⟹   ENSP00000444236
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,856,168 - 62,888,875 (+)Ensembl
RefSeq Acc Id: ENST00000535768
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,884,455 - 62,888,169 (+)Ensembl
RefSeq Acc Id: ENST00000536981   ⟹   ENSP00000444439
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,881,725 - 62,888,845 (+)Ensembl
RefSeq Acc Id: ENST00000537508
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,881,668 - 62,885,314 (+)Ensembl
RefSeq Acc Id: ENST00000537839
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,881,699 - 62,883,998 (+)Ensembl
RefSeq Acc Id: ENST00000538084   ⟹   ENSP00000440001
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,870,814 - 62,881,994 (+)Ensembl
RefSeq Acc Id: ENST00000538682
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,881,709 - 62,888,455 (+)Ensembl
RefSeq Acc Id: ENST00000539458   ⟹   ENSP00000438032
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,880,896 - 62,882,037 (+)Ensembl
RefSeq Acc Id: ENST00000539507   ⟹   ENSP00000440819
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,885,177 - 62,888,860 (+)Ensembl
RefSeq Acc Id: ENST00000539891   ⟹   ENSP00000438353
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,881,699 - 62,888,368 (+)Ensembl
RefSeq Acc Id: ENST00000541372   ⟹   ENSP00000444250
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,880,896 - 62,881,290 (+)Ensembl
RefSeq Acc Id: ENST00000541425   ⟹   ENSP00000445858
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,882,961 - 62,885,587 (+)Ensembl
RefSeq Acc Id: ENST00000541649
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,881,698 - 62,882,386 (+)Ensembl
RefSeq Acc Id: ENST00000542793
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,887,870 - 62,888,520 (+)Ensembl
RefSeq Acc Id: ENST00000542922
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,883,348 - 62,888,858 (+)Ensembl
RefSeq Acc Id: ENST00000544377   ⟹   ENSP00000442135
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,880,422 - 62,881,428 (+)Ensembl
RefSeq Acc Id: ENST00000546253
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,881,722 - 62,884,512 (+)Ensembl
RefSeq Acc Id: ENST00000546312
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,882,775 - 62,885,387 (+)Ensembl
RefSeq Acc Id: ENST00000679594
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,881,699 - 62,888,845 (+)Ensembl
RefSeq Acc Id: ENST00000679908   ⟹   ENSP00000506238
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,880,896 - 62,888,880 (+)Ensembl
RefSeq Acc Id: ENST00000680002   ⟹   ENSP00000506366
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,856,004 - 62,888,880 (+)Ensembl
RefSeq Acc Id: ENST00000680134   ⟹   ENSP00000504939
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,880,891 - 62,888,841 (+)Ensembl
RefSeq Acc Id: ENST00000680297   ⟹   ENSP00000506230
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,880,863 - 62,888,805 (+)Ensembl
RefSeq Acc Id: ENST00000680610   ⟹   ENSP00000505079
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,880,863 - 62,888,849 (+)Ensembl
RefSeq Acc Id: ENST00000680631   ⟹   ENSP00000506006
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,879,891 - 62,888,880 (+)Ensembl
RefSeq Acc Id: ENST00000680654
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,880,896 - 62,888,849 (+)Ensembl
RefSeq Acc Id: ENST00000680725   ⟹   ENSP00000505585
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,856,111 - 62,888,880 (+)Ensembl
RefSeq Acc Id: ENST00000680729   ⟹   ENSP00000505639
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,856,004 - 62,888,880 (+)Ensembl
RefSeq Acc Id: ENST00000681107   ⟹   ENSP00000505253
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,880,896 - 62,888,849 (+)Ensembl
RefSeq Acc Id: ENST00000681215
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,856,161 - 62,886,196 (+)Ensembl
RefSeq Acc Id: ENST00000681232   ⟹   ENSP00000506460
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,880,896 - 62,888,880 (+)Ensembl
RefSeq Acc Id: ENST00000681467   ⟹   ENSP00000506217
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,856,102 - 62,888,880 (+)Ensembl
RefSeq Acc Id: ENST00000681563
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,880,896 - 62,888,870 (+)Ensembl
RefSeq Acc Id: ENST00000681569   ⟹   ENSP00000506498
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,856,109 - 62,888,880 (+)Ensembl
RefSeq Acc Id: ENST00000681657   ⟹   ENSP00000505110
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1162,880,896 - 62,888,880 (+)Ensembl
RefSeq Acc Id: NM_001012662   ⟹   NP_001012680
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381162,856,109 - 62,888,860 (+)NCBI
GRCh371162,623,484 - 62,656,355 (+)ENTREZGENE
Build 361162,380,094 - 62,412,929 (+)NCBI Archive
HuRef1158,952,521 - 58,985,401 (+)ENTREZGENE
CHM1_11162,506,504 - 62,539,366 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001012664   ⟹   NP_001012682
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381162,856,109 - 62,888,860 (+)NCBI
GRCh371162,623,484 - 62,656,355 (+)ENTREZGENE
Build 361162,380,094 - 62,412,929 (+)NCBI Archive
HuRef1158,952,521 - 58,985,401 (+)ENTREZGENE
CHM1_11162,506,504 - 62,539,366 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001013251   ⟹   NP_001013269
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381162,880,896 - 62,888,860 (+)NCBI
GRCh371162,623,484 - 62,656,355 (+)ENTREZGENE
Build 361162,404,863 - 62,412,929 (+)NCBI Archive
HuRef1158,952,521 - 58,985,401 (+)ENTREZGENE
CHM1_11162,531,355 - 62,539,366 (+)NCBI
Sequence:
RefSeq Acc Id: NM_002394   ⟹   NP_002385
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381162,856,109 - 62,888,860 (+)NCBI
GRCh371162,623,484 - 62,656,355 (+)ENTREZGENE
Build 361162,380,094 - 62,412,929 (+)NCBI Archive
HuRef1158,952,521 - 58,985,401 (+)ENTREZGENE
CHM1_11162,506,504 - 62,539,366 (+)NCBI
Sequence:
RefSeq Acc Id: NR_037193
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381162,881,699 - 62,888,860 (+)NCBI
GRCh371162,623,484 - 62,656,355 (+)ENTREZGENE
HuRef1158,952,521 - 58,985,401 (+)ENTREZGENE
CHM1_11162,532,182 - 62,539,366 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_002385   ⟸   NM_002394
- Peptide Label: isoform c
- UniProtKB: P08195 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001012680   ⟸   NM_001012662
- Peptide Label: isoform b
- UniProtKB: P08195 (UniProtKB/Swiss-Prot),   J3KPF3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001012682   ⟸   NM_001012664
- Peptide Label: isoform e
- UniProtKB: P08195 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001013269   ⟸   NM_001013251
- Peptide Label: isoform f
- UniProtKB: P08195 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000444250   ⟸   ENST00000541372
RefSeq Acc Id: ENSP00000445858   ⟸   ENST00000541425
RefSeq Acc Id: ENSP00000442135   ⟸   ENST00000544377
RefSeq Acc Id: ENSP00000367121   ⟸   ENST00000377889
RefSeq Acc Id: ENSP00000367123   ⟸   ENST00000377891
RefSeq Acc Id: ENSP00000367122   ⟸   ENST00000377890
RefSeq Acc Id: ENSP00000340815   ⟸   ENST00000338663
RefSeq Acc Id: ENSP00000444236   ⟸   ENST00000535296
RefSeq Acc Id: ENSP00000444439   ⟸   ENST00000536981
RefSeq Acc Id: ENSP00000440001   ⟸   ENST00000538084
RefSeq Acc Id: ENSP00000440819   ⟸   ENST00000539507
RefSeq Acc Id: ENSP00000438032   ⟸   ENST00000539458
RefSeq Acc Id: ENSP00000438353   ⟸   ENST00000539891
RefSeq Acc Id: ENSP00000505639   ⟸   ENST00000680729
RefSeq Acc Id: ENSP00000506460   ⟸   ENST00000681232
RefSeq Acc Id: ENSP00000506230   ⟸   ENST00000680297
RefSeq Acc Id: ENSP00000505585   ⟸   ENST00000680725
RefSeq Acc Id: ENSP00000506498   ⟸   ENST00000681569
RefSeq Acc Id: ENSP00000504939   ⟸   ENST00000680134
RefSeq Acc Id: ENSP00000506006   ⟸   ENST00000680631
RefSeq Acc Id: ENSP00000505079   ⟸   ENST00000680610
RefSeq Acc Id: ENSP00000505110   ⟸   ENST00000681657
RefSeq Acc Id: ENSP00000506217   ⟸   ENST00000681467
RefSeq Acc Id: ENSP00000506366   ⟸   ENST00000680002
RefSeq Acc Id: ENSP00000505253   ⟸   ENST00000681107
RefSeq Acc Id: ENSP00000506238   ⟸   ENST00000679908
Protein Domains
Aamy   DUF3459   SLC3A2_N

Promoters
RGD ID:6789540
Promoter ID:HG_KWN:13144
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000365607,   NM_001012661,   NM_001012662,   NM_001012663,   NM_001012664,   NM_002394,   NR_003098,   UC001NVO.1,   UC001NVP.1,   UC001NVQ.1,   UC001NVR.1,   UC001NVS.1,   UC001NVT.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361162,378,686 - 62,380,037 (-)MPROMDB
RGD ID:6789387
Promoter ID:HG_KWN:13146
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_001013251
Position:
Human AssemblyChrPosition (strand)Source
Build 361162,403,891 - 62,405,487 (+)MPROMDB
RGD ID:7220741
Promoter ID:EPDNEW_H16115
Type:initiation region
Name:SLC3A2_3
Description:solute carrier family 3 member 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H16116  EPDNEW_H16117  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381162,856,161 - 62,856,221EPDNEW
RGD ID:7220739
Promoter ID:EPDNEW_H16116
Type:initiation region
Name:SLC3A2_1
Description:solute carrier family 3 member 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H16115  EPDNEW_H16117  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381162,880,896 - 62,880,956EPDNEW
RGD ID:7220745
Promoter ID:EPDNEW_H16117
Type:initiation region
Name:SLC3A2_2
Description:solute carrier family 3 member 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H16116  EPDNEW_H16115  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381162,881,699 - 62,881,759EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 11q12.3(chr11:62433886-63096003)x3 copy number gain See cases [RCV000053620] Chr11:62433886..63096003 [GRCh38]
Chr11:62201358..62863475 [GRCh37]
Chr11:61957934..62620051 [NCBI36]
Chr11:11q12.3
pathogenic
GRCh38/hg38 11q12.3(chr11:62452571-62862781)x3 copy number gain See cases [RCV000053621] Chr11:62452571..62862781 [GRCh38]
Chr11:62220043..62630253 [GRCh37]
Chr11:61976619..62386829 [NCBI36]
Chr11:11q12.3
pathogenic
NM_001012662.2(SLC3A2):c.-1259C>T single nucleotide variant Malignant melanoma [RCV000062319] Chr11:62855011 [GRCh38]
Chr11:62622483 [GRCh37]
Chr11:62379059 [NCBI36]
Chr11:11q12.3
not provided
GRCh38/hg38 11q12.3(chr11:62249520-62946093)x3 copy number gain See cases [RCV000138411] Chr11:62249520..62946093 [GRCh38]
Chr11:62016992..62713565 [GRCh37]
Chr11:61773568..62470141 [NCBI36]
Chr11:11q12.3
pathogenic
GRCh37/hg19 11q12.3(chr11:61840997-62987330)x1 copy number loss See cases [RCV000448355] Chr11:61840997..62987330 [GRCh37]
Chr11:11q12.3
likely pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470) copy number gain See cases [RCV000511729] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25
pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470)x3 copy number gain See cases [RCV000510881] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25
pathogenic
GRCh37/hg19 11p15.5-q25(chr11:198510-134934063)x3 copy number gain not provided [RCV000737348] Chr11:198510..134934063 [GRCh37]
Chr11:11p15.5-q25
pathogenic
GRCh37/hg19 11p15.5-q25(chr11:70864-134938470)x3 copy number gain not provided [RCV000749874] Chr11:70864..134938470 [GRCh37]
Chr11:11p15.5-q25
pathogenic
NM_001012662.3(SLC3A2):c.301+3G>A single nucleotide variant not provided [RCV000962171] Chr11:62876882 [GRCh38]
Chr11:62644354 [GRCh37]
Chr11:11q12.3
benign
NM_001013251.3(SLC3A2):c.253C>T (p.Leu85=) single nucleotide variant not provided [RCV000972289] Chr11:62881276 [GRCh38]
Chr11:62648748 [GRCh37]
Chr11:11q12.3
benign
NM_001012662.3(SLC3A2):c.112+8A>T single nucleotide variant not provided [RCV000901154] Chr11:62856389 [GRCh38]
Chr11:62623861 [GRCh37]
Chr11:11q12.3
benign
NM_001013251.3(SLC3A2):c.1243C>T (p.Pro415Ser) single nucleotide variant not provided [RCV000972126] Chr11:62888346 [GRCh38]
Chr11:62655818 [GRCh37]
Chr11:11q12.3
benign
NM_001013251.3(SLC3A2):c.1326G>A (p.Ala442=) single nucleotide variant not provided [RCV000962945] Chr11:62888429 [GRCh38]
Chr11:62655901 [GRCh37]
Chr11:11q12.3
likely benign
NM_001013251.3(SLC3A2):c.291T>G (p.Ala97=) single nucleotide variant not provided [RCV000900567] Chr11:62881314 [GRCh38]
Chr11:62648786 [GRCh37]
Chr11:11q12.3
benign
NM_001013251.3(SLC3A2):c.1013G>T (p.Arg338Met) single nucleotide variant not provided [RCV000896397] Chr11:62885478 [GRCh38]
Chr11:62652950 [GRCh37]
Chr11:11q12.3
likely benign
NM_001013251.3(SLC3A2):c.684G>A (p.Lys228=) single nucleotide variant not provided [RCV000896657] Chr11:62882993 [GRCh38]
Chr11:62650465 [GRCh37]
Chr11:11q12.3
likely benign
NM_001013251.3(SLC3A2):c.1471A>C (p.Lys491Gln) single nucleotide variant not provided [RCV000949348] Chr11:62888574 [GRCh38]
Chr11:62656046 [GRCh37]
Chr11:11q12.3
benign
GRCh37/hg19 11q12.3(chr11:62314663-62788240)x3 copy number gain not provided [RCV000849841] Chr11:62314663..62788240 [GRCh37]
Chr11:11q12.3
uncertain significance
GRCh37/hg19 11q12.3(chr11:62487052-62788240)x3 copy number gain not provided [RCV000846292] Chr11:62487052..62788240 [GRCh37]
Chr11:11q12.3
uncertain significance
NM_001013251.3(SLC3A2):c.141G>A (p.Val47=) single nucleotide variant not provided [RCV000906598] Chr11:62881164 [GRCh38]
Chr11:62648636 [GRCh37]
Chr11:11q12.3
likely benign
NM_001013251.3(SLC3A2):c.424+9A>G single nucleotide variant not provided [RCV000930841] Chr11:62881456 [GRCh38]
Chr11:62648928 [GRCh37]
Chr11:11q12.3
likely benign
NM_001013251.3(SLC3A2):c.1026C>G (p.Ser342=) single nucleotide variant not provided [RCV000935886] Chr11:62885491 [GRCh38]
Chr11:62652963 [GRCh37]
Chr11:11q12.3
likely benign
NM_001013251.3(SLC3A2):c.1303C>T (p.Leu435=) single nucleotide variant not provided [RCV000956952] Chr11:62888406 [GRCh38]
Chr11:62655878 [GRCh37]
Chr11:11q12.3
benign
Single allele deletion Intellectual disability [RCV001293382] Chr11:118359328..118372573 [GRCh37]
Chr11:11p15.3-q23.3
pathogenic
NC_000011.9:g.(?_59596957)_(68707199_?)dup duplication Epilepsy, familial temporal lobe, 8 [RCV001372442] Chr11:59596957..68707199 [GRCh37]
Chr11:11q12.1-13.3
uncertain significance

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:11026 AgrOrtholog
COSMIC SLC3A2 COSMIC
Ensembl Genes ENSG00000168003 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000340815 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000367121 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000367122 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000367123 ENTREZGENE, UniProtKB/TrEMBL
  ENSP00000438032 UniProtKB/TrEMBL
  ENSP00000438353 UniProtKB/TrEMBL
  ENSP00000440001 UniProtKB/TrEMBL
  ENSP00000440819 UniProtKB/TrEMBL
  ENSP00000442135 UniProtKB/TrEMBL
  ENSP00000444236 UniProtKB/TrEMBL
  ENSP00000444250 UniProtKB/TrEMBL
  ENSP00000444439 UniProtKB/TrEMBL
  ENSP00000445858 UniProtKB/TrEMBL
Ensembl Transcript ENST00000338663 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000377889 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000377890 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000377891 ENTREZGENE, UniProtKB/TrEMBL
  ENST00000535296 UniProtKB/TrEMBL
  ENST00000536981 UniProtKB/TrEMBL
  ENST00000538084 UniProtKB/TrEMBL
  ENST00000538682 ENTREZGENE
  ENST00000539458 UniProtKB/TrEMBL
  ENST00000539507 UniProtKB/TrEMBL
  ENST00000539891 UniProtKB/TrEMBL
  ENST00000541372 UniProtKB/TrEMBL
  ENST00000541425 UniProtKB/TrEMBL
  ENST00000544377 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.1180 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000168003 GTEx
HGNC ID HGNC:11026 ENTREZGENE
Human Proteome Map SLC3A2 Human Proteome Map
InterPro DUF3459 UniProtKB/TrEMBL
  Glyco_hydro_13_cat_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glyco_hydro_b UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glycoside_hydrolase_SF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SLC3A2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SLC3A2_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:6520 UniProtKB/Swiss-Prot
NCBI Gene 6520 ENTREZGENE
OMIM 158070 OMIM
PANTHER PTHR46673 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Alpha-amylase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DUF3459 UniProtKB/TrEMBL
  SLC3A2_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA35894 PharmGKB
SMART Aamy UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF51445 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt 4F2_HUMAN UniProtKB/Swiss-Prot
  A0A024R599_HUMAN UniProtKB/TrEMBL
  F5GZI0_HUMAN UniProtKB/TrEMBL
  F5GZR9_HUMAN UniProtKB/TrEMBL
  F5GZS6_HUMAN UniProtKB/TrEMBL
  F5H056_HUMAN UniProtKB/TrEMBL
  F5H0E2_HUMAN UniProtKB/TrEMBL
  F5H867_HUMAN UniProtKB/TrEMBL
  H0YFS2_HUMAN UniProtKB/TrEMBL
  H0YFX4_HUMAN UniProtKB/TrEMBL
  H0YH36_HUMAN UniProtKB/TrEMBL
  J3KPF3 ENTREZGENE, UniProtKB/TrEMBL
  P08195 ENTREZGENE
UniProt Secondary Q13543 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-23 SLC3A2  solute carrier family 3 member 2    solute carrier family 3 (amino acid transporter heavy chain), member 2  Symbol and/or name change 5135510 APPROVED
2013-07-23 SLC3A2  solute carrier family 3 (amino acid transporter heavy chain), member 2    solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2  Symbol and/or name change 5135510 APPROVED