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Gene: COL18A1 (collagen type XVIII alpha 1 chain) Homo sapiens
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Symbol: COL18A1
Name: collagen type XVIII alpha 1 chain
RGD ID: 736032
Description: Exhibits identical protein binding activity. Predicted to be involved in angiogenesis; endothelial cell morphogenesis; and extracellular matrix organization. Localizes to collagen-containing extracellular matrix and extracellular exosome. Implicated in primary angle-closure glaucoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: antiangiogenic agent; collagen alpha-1(XVIII) chain; collagen alpha-1(XVIII) chain isoform 1 preproprotein; collagen type XVIII alpha 1; collagen, type XVIII, alpha 1; endostatin; FLJ27325; FLJ34914; GLCC; KNO; KNO1; Knobloch syndrome; KS; MGC74745; multi-functional protein MFP
Orthologs:
Mus musculus (house mouse) : Col18a1 (collagen, type XVIII, alpha 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Col18a1 (collagen type XVIII alpha 1 chain)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Col18a1 (collagen type XVIII alpha 1 chain)
Pan paniscus (bonobo/pygmy chimpanzee) : COL18A1 (collagen type XVIII alpha 1 chain)
Canis lupus familiaris (dog) : COL18A1 (collagen type XVIII alpha 1 chain)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Col18a1 (collagen type XVIII alpha 1 chain)
Sus scrofa (pig) : COL18A1 (collagen type XVIII alpha 1 chain)
Chlorocebus sabaeus (African green monkey) : COL18A1 (collagen type XVIII alpha 1 chain)
Heterocephalus glaber (naked mole-rat) : Col18a1 (collagen type XVIII alpha 1 chain)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2145,405,165 - 45,513,720 (+)EnsemblGRCh38hg38GRCh38
GRCh382145,405,165 - 45,513,720 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372146,825,058 - 46,933,634 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362145,649,525 - 45,758,062 (+)NCBINCBI36hg18NCBI36
Build 342145,649,524 - 45,758,061NCBI
Celera2131,935,820 - 32,044,503 (+)NCBI
Cytogenetic Map21q22.3NCBI
HuRef2132,201,756 - 32,310,095 (+)NCBIHuRef
CHM1_12146,385,890 - 46,494,464 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on COL18A1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736032
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-10-06
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.