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Gene: POR (cytochrome p450 oxidoreductase) Homo sapiens
Symbol: POR
Name: cytochrome p450 oxidoreductase
RGD ID: 68468
Description: Exhibits NADPH-hemoprotein reductase activity. Involved in cellular organofluorine metabolic process; oxidation-reduction process; and positive regulation of monooxygenase activity. Localizes to intracellular membrane-bounded organelle. Implicated in Antley-Bixler syndrome and congenital adrenal hyperplasia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CPR; CYPOR; DKFZp686G04235; FLJ26468; NADPH--cytochrome P450 reductase; NADPH--hemoprotein reductase; NADPH-dependent cytochrome P450 reductase; P450 (cytochrome) oxidoreductase; P450R
Mus musculus (house mouse) : Por (P450 (cytochrome) oxidoreductase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Por (cytochrome p450 oxidoreductase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Por (P450 (cytochrome) oxidoreductase)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100990437 (NADPH--cytochrome P450 reductase)
Canis lupus familiaris (dog) : POR (cytochrome p450 oxidoreductase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101965545 (NADPH--cytochrome P450 reductase)
Sus scrofa (pig) : POR (P450 (cytochrome) oxidoreductase)
Chlorocebus sabaeus (African green monkey) : POR (P450 (cytochrome) oxidoreductase)
Heterocephalus glaber (naked mole-rat) : LOC101712555 (NADPH--cytochrome P450 reductase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl775,899,200 - 75,986,855 (+)EnsemblGRCh38hg38GRCh38
GRCh38775,915,155 - 75,986,855 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37775,544,420 - 75,616,173 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36775,382,356 - 75,454,109 (+)NCBINCBI36hg18NCBI36
Build 34775,227,957 - 75,260,823NCBI
Celera770,412,991 - 70,484,717 (+)NCBI
Cytogenetic Map7q11.23NCBI
HuRef770,631,215 - 70,702,985 (+)NCBIHuRef
CHM1_1775,474,511 - 75,546,243 (+)NCBICHM1_1
CRA_TCAGchr7v2774,877,484 - 74,949,237 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on POR
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68468
Created: 2001-07-11
Species: Homo sapiens
Last Modified: 2020-11-10
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.