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Gene: U2AF1 (U2 small nuclear RNA auxiliary factor 1) Homo sapiens
Symbol: U2AF1
Name: U2 small nuclear RNA auxiliary factor 1
Description: Exhibits RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Localizes to U2AF; catalytic step 2 spliceosome; and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp313J1712; FP793; RN; RNU2AF1; splicing factor U2AF 35 kDa subunit; splicing factor U2AF 35kDa subunit; U2 auxiliary factor 35 kDa subunit; U2 small nuclear ribonucleoprotein auxillary factor, 35-KD subunit; U2 small nuclear RNA auxillary factor 1; U2 snRNP auxiliary factor small subunit; U2(RNU2) small nuclear RNA auxiliary factor binding protein; U2AF35; U2AFBP
Mus musculus (house mouse) : U2af1 (U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : U2af1 (U2 small nuclear RNA auxiliary factor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : U2af1 (U2 small nuclear RNA auxiliary factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100973922 (splicing factor U2AF 35 kDa subunit-like protein)
Canis lupus familiaris (dog) : U2AF1 (U2 small nuclear RNA auxiliary factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : U2af1 (U2 small nuclear RNA auxiliary factor 1)
Sus scrofa (pig) : U2AF1 (U2 small nuclear RNA auxiliary factor 1)
Chlorocebus sabaeus (African green monkey) : U2AF1 (U2 small nuclear RNA auxiliary factor 1)
Heterocephalus glaber (naked mole-rat) : U2af1 (U2 small nuclear RNA auxiliary factor 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2143,092,956 - 43,107,587 (-)EnsemblGRCh38hg38GRCh38
GRCh382143,092,956 - 43,108,291 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372144,513,066 - 44,527,716 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362143,386,135 - 43,400,757 (-)NCBINCBI36hg18NCBI36
Build 342143,386,135 - 43,400,703NCBI
Celera2129,665,729 - 29,680,351 (-)NCBI
Cytogenetic Map21q22.3NCBI
HuRef2129,931,179 - 29,945,801 (-)NCBIHuRef
CHM1_12144,073,930 - 44,088,542 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on U2AF1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1349504
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-07-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.