FLNA (filamin A) - Rat Genome Database

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Gene: FLNA (filamin A) Homo sapiens
Symbol: FLNA
Name: filamin A
RGD ID: 1354471
HGNC Page HGNC:3754
Description: Enables several functions, including enzyme binding activity; protein homodimerization activity; and signaling receptor binding activity. Involved in several processes, including negative regulation of nitrogen compound metabolic process; positive regulation of transport; and protein localization to membrane. Acts upstream of or within mitotic spindle assembly. Located in several cellular components, including actin cytoskeleton; cell-cell junction; and cytosol. Part of Myb complex and nucleolus. Implicated in X-linked chronic idiopathic intestinal pseudo-obstruction; bone development disease (multiple); heart valve disease (multiple); periventricular nodular heterotopia; and terminal osseous dysplasia. Biomarker of epilepsy; thoracic aortic aneurysm; and tuberous sclerosis.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: ABP-280; ABPX; actin binding protein 280; alpha filamin; alpha-filamin; CSBS; CVD1; DKFZp434P031; endothelial actin-binding protein; FG syndrome 2; FGS2; filamin 1; filamin A, alpha; filamin-1; filamin-A; FLJ43642; FLN; FLN-A; FLN1; FMD; MNS; NHBP; non-muscle filamin; OPD; OPD1; OPD2; XLVD; XMVD
RGD Orthologs
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38X154,348,531 - 154,374,634 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX154,348,524 - 154,374,634 (-)EnsemblGRCh38hg38GRCh38
GRCh37X153,576,899 - 153,603,002 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X153,230,091 - 153,252,845 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X153,097,811 - 153,123,776NCBI
CeleraX153,737,962 - 153,764,068 (-)NCBICelera
Cytogenetic MapXq28NCBI
HuRefX142,154,186 - 142,180,218 (-)NCBIHuRef
CHM1_1X153,488,516 - 153,514,622 (-)NCBICHM1_1
T2T-CHM13v2.0X152,585,064 - 152,611,166 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)