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Gene: HLA-C (major histocompatibility complex, class I, C) Homo sapiens
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Symbol: HLA-C
Name: major histocompatibility complex, class I, C
Description: Exhibits TAP binding activity and peptide antigen binding activity. Involved in antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent. Localizes to several cellular components, including Golgi apparatus; MHC class I protein complex; and cell surface. Implicated in allergic asthma; human immunodeficiency virus infectious disease; and psoriasis 1.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: alpha chain of MHC class II; class I MHC antigen HLA-B heavy chain; D6S204; FLJ27082; HLA C; HLA class I antigen; HLA class I heavy chain; HLA class I histocompatibility antigen C alpha chain; HLA class I histocompatibility antigen Cw-1 alpha chain; HLA class I histocompatibility antigen, C alpha chain; HLA class I histocompatibility antigen, Cw-1 alpha chain; HLA class I histocompatibility antigen, Cw-12 alpha chain; HLA class I histocompatibility antigen, Cw-14 alpha chain; HLA class I histocompatibility antigen, Cw-15 alpha chain; HLA class I histocompatibility antigen, Cw-16 alpha chain; HLA class I histocompatibility antigen, Cw-17 alpha chain; HLA class I histocompatibility antigen, Cw-18 alpha chain; HLA class I histocompatibility antigen, Cw-2 alpha chain; HLA class I histocompatibility antigen, Cw-4 alpha chain; HLA class I histocompatibility antigen, Cw-6 alpha chain; HLA class I histocompatibility antigen, Cw-7 alpha chain; HLA class I histocompatibility antigen, Cw-8 alpha chain; HLA-C (Cw*1201); HLA-C alpha chain; HLA-C alpha chain (HLA-Cw*15v); HLA-C alpha chain for Cw*18GB; HLA-C alpha-chain; HLA-C antigen; HLA-Cw; HLA-Cw*04GB; HLA-Cw*050x; HLA-Cw*1702; HLA-Cw*18GB; HLA-Cw-1503; HLA-Cw12; HLA-JY3; HLAC; HLC-C; human leukocyte antigen-C alpha chain; leucocyte antigen C; leucocyte antigen Cw; leukocyte antigen C; leukocyte antigen-C alpha chain; major histocompatibility antigen HLA-C; MHC; MHC clas I antigen; MHC class 1 antigen; MHC class 1 antigen, alpha chain; MHC Class I antigen; MHC class I antigen Cw*1; MHC class I antigen Cw*12; MHC class I antigen Cw*14; MHC class I antigen Cw*15; MHC class I antigen Cw*16; MHC class I antigen Cw*17; MHC class I antigen Cw*18; MHC class I antigen Cw*2; MHC class I antigen Cw*3; MHC class I antigen Cw*4; MHC class I antigen Cw*6; MHC class I antigen Cw*7; MHC class I antigen Cw*8; MHC class I antigen heavy chain HLA-C; MHC class I antigen HLA-C; MHC class I histocompatibility antigen; MHC class I HLA-C; MHC class I HLA-Cw*0803; MHC class I molecule; MHC class I protein HLA-C heavy chain; MHC class II antigen; psoriasis susceptibility 1; PSORS1; surface antigen; truncated MHC class I antigen
Orthologs:
No known orthologs. homologs ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl631,268,749 - 31,272,130 (-)EnsemblGRCh38hg38GRCh38
GRCh38631,268,749 - 31,272,092 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37631,236,526 - 31,239,913 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36631,344,508 - 31,347,834 (-)NCBINCBI36hg18NCBI36
Build 34631,344,508 - 31,347,834NCBI
Celera632,835,242 - 32,838,561 (-)NCBI
Cytogenetic Map6p21.33NCBI
HuRef631,037,198 - 31,040,575 (-)NCBIHuRef
CHM1_1631,239,250 - 31,242,627 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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Sequence

Nucleotide Sequences