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Gene: TUBA1B (tubulin alpha 1b) Homo sapiens
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Symbol: TUBA1B
Name: tubulin alpha 1b
Description: Exhibits double-stranded RNA binding activity and ubiquitin protein ligase binding activity. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Localizes to microtubule; PARTICIPATES IN docetaxel pharmacodynamics pathway; tyrosinemia type III pathway; vinblastine pharmacodynamics pathway; INTERACTS WITH 3-isobutyl-1-methyl-7H-xanthine; 4-hydroxynon-2-enal; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: alpha tubulin; alpha-tubulin ubiquitous; K-ALPHA-1; tubulin alpha-1B chain; tubulin alpha-ubiquitous chain; tubulin K-alpha-1; tubulin, alpha 1b; tubulin, alpha, ubiquitous
Orthologs:
Mus musculus (house mouse) : Tuba1b (tubulin, alpha 1B)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tuba1b (tubulin, alpha 1B)  Alliance
Canis lupus familiaris (dog) : LOC106557476 (tubulin alpha-1A chain)
Sus scrofa (pig) : LOC100158003 (tubulin alpha-1D chain)
Chlorocebus sabaeus (African green monkey) : TUBA1B (tubulin alpha 1b)
Heterocephalus glaber (naked mole-rat) : Tuba1b (tubulin alpha 1b)
more info ...
Related Pseudogenes: TUBAP11   TUBAP12   TUBAP2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1249,127,782 - 49,131,397 (-)EnsemblGRCh38hg38GRCh38
GRCh381249,127,782 - 49,131,395 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371249,521,565 - 49,525,304 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361247,807,832 - 47,811,571 (-)NCBINCBI36hg18NCBI36
Celera1248,315,719 - 48,319,458 (-)NCBI
Cytogenetic Map12q13.12NCBI
HuRef1246,552,484 - 46,556,221 (-)NCBIHuRef
CHM1_11249,487,375 - 49,491,114 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on TUBA1B
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1603700
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-07-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.