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Gene: AK2 (adenylate kinase 2) Homo sapiens
Symbol: AK2
Name: adenylate kinase 2
Description: Exhibits adenylate kinase activity. Predicted to be involved in nucleobase-containing small molecule interconversion. Localizes to extracellular exosome. Implicated in reticular dysgenesis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: adenylate kinase 2, mitochondrial; adenylate kinase isoenzyme 2, mitochondrial; adenylate monophosphate kinase; ADK2; AK 2; ATP-AMP transphosphorylase 2; ATP:AMP phosphotransferase; testis secretory sperm-binding protein Li 220n
Mus musculus (house mouse) : Ak2 (adenylate kinase 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ak2 (adenylate kinase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ak2 (adenylate kinase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : AK2 (adenylate kinase 2)
Canis lupus familiaris (dog) : AK2 (adenylate kinase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ak2 (adenylate kinase 2)
Sus scrofa (pig) : AK2 (adenylate kinase 2)
Chlorocebus sabaeus (African green monkey) : AK2 (adenylate kinase 2)
Heterocephalus glaber (naked mole-rat) : Ak2 (adenylate kinase 2)
more info ...
Related Pseudogenes: AK2P1   AK2P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl133,007,940 - 33,080,996 (-)EnsemblGRCh38hg38GRCh38
GRCh38133,007,940 - 33,036,911 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37133,473,541 - 33,502,512 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36133,246,173 - 33,275,079 (-)NCBINCBI36hg18NCBI36
Build 34133,147,675 - 33,171,564NCBI
Celera131,743,797 - 31,772,701 (-)NCBI
Cytogenetic Map1p35.1NCBI
HuRef131,590,115 - 31,619,093 (-)NCBIHuRef
CHM1_1133,589,052 - 33,618,018 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on AK2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735291
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-05-05
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.