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Gene: OSBPL1A (oxysterol binding protein like 1A) Homo sapiens
Symbol: OSBPL1A
Name: oxysterol binding protein like 1A
Description: Exhibits cholesterol binding activity. Predicted to be involved in antigen processing and presentation of exogenous peptide antigen via MHC class II and bile acid biosynthetic process. Localizes to late endosome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ10217; ORP-1; ORP1; OSBP-related protein 1; OSBPL1B; oxysterol binding protein-like 1A; oxysterol binding protein-like 1B; oxysterol-binding protein-related protein 1; oxysterol-binding protein-related protein 1 variant 1; oxysterol-binding protein-related protein 1 variant 2
Mus musculus (house mouse) : Osbpl1a (oxysterol binding protein-like 1A)  MGI  Alliance
Rattus norvegicus (Norway rat) : Osbpl1a (oxysterol binding protein-like 1A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Osbpl1a (oxysterol binding protein like 1A)
Pan paniscus (bonobo/pygmy chimpanzee) : OSBPL1A (oxysterol binding protein like 1A)
Canis lupus familiaris (dog) : OSBPL1A (oxysterol binding protein like 1A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Osbpl1a (oxysterol binding protein like 1A)
Sus scrofa (pig) : OSBPL1A (oxysterol binding protein like 1A)
Chlorocebus sabaeus (African green monkey) : OSBPL1A (oxysterol binding protein like 1A)
Heterocephalus glaber (naked mole-rat) : Osbpl1a (oxysterol binding protein like 1A)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1824,162,045 - 24,397,880 (-)EnsemblGRCh38hg38GRCh38
GRCh381824,162,045 - 24,397,882 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371821,742,009 - 21,977,846 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361819,996,007 - 20,231,788 (-)NCBINCBI36hg18NCBI36
Build 341819,996,010 - 20,231,788NCBI
Celera1818,558,319 - 18,792,861 (-)NCBI
Cytogenetic Map18q11.2NCBI
HuRef1818,598,065 - 18,833,825 (-)NCBIHuRef
CHM1_11821,669,277 - 21,904,868 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on OSBPL1A
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731675
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.