Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | ISO | Pycr3 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of PYCR3 mRNA] | CTD | PMID:31150632 | (1->4)-beta-D-glucan | multiple interactions | ISO | Pycr3 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of PYCR3 mRNA | CTD | PMID:36331819 | 1,2-dimethylhydrazine | decreases expression | ISO | Pycr3 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of PYCR3 mRNA | CTD | PMID:22206623 | 17beta-estradiol | increases expression | EXP | | 6480464 | Estradiol results in increased expression of PYCR3 mRNA | CTD | PMID:31614463 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Pycr3 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of PYCR3 mRNA | CTD | PMID:21570461 | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Pycr3 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of PYCR3 mRNA | CTD | PMID:20188158 | 3-chloropropane-1,2-diol | increases expression | ISO | Pycr3 (Rattus norvegicus) | 6480464 | alpha-Chlorohydrin results in increased expression of PYCR3 protein | CTD | PMID:34915118 | aristolochic acid A | decreases expression | EXP | | 6480464 | aristolochic acid I results in decreased expression of PYCR3 mRNA | CTD | PMID:33212167 | astemizole | increases expression | ISO | Pycr3 (Rattus norvegicus) | 6480464 | Astemizole results in increased expression of PYCR3 mRNA | CTD | PMID:20221588 | bis(2-ethylhexyl) phthalate | decreases expression | ISO | Pycr3 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in decreased expression of PYCR3 mRNA | CTD | PMID:28085963 | bisphenol A | increases expression | ISO | Pycr3 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of PYCR3 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | Pycr3 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of PYCR3 mRNA | CTD | PMID:35598803 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of PYCR3 mRNA | CTD | PMID:29275510 | Brodifacoum | decreases expression | ISO | Pycr3 (Rattus norvegicus) | 6480464 | bromfenacoum results in decreased expression of PYCR3 protein | CTD | PMID:28903499 | carbon nanotube | increases expression | ISO | Pycr3 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | CGP 52608 | multiple interactions | EXP | | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to PYCR3 gene] | CTD | PMID:28238834 | copper atom | multiple interactions | EXP | | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of PYCR3 mRNA | CTD | PMID:20971185 | copper(0) | multiple interactions | EXP | | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of PYCR3 mRNA | CTD | PMID:20971185 | cylindrospermopsin | increases expression | EXP | | 6480464 | cylindrospermopsin results in increased expression of PYCR3 mRNA | CTD | PMID:24921660 | dibutyl phthalate | decreases expression | ISO | Pycr3 (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of PYCR3 mRNA | CTD | PMID:21266533 | dioxygen | decreases expression | EXP | | 6480464 | Oxygen deficiency results in decreased expression of PYCR3 mRNA | CTD | PMID:26516004 | elemental selenium | multiple interactions | EXP | | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of PYCR3 mRNA | CTD | PMID:19244175 | ethyl methanesulfonate | decreases expression | EXP | | 6480464 | Ethyl Methanesulfonate results in decreased expression of PYCR3 mRNA | CTD | PMID:23649840 | fenthion | increases expression | ISO | Pycr3 (Mus musculus) | 6480464 | Fenthion results in increased expression of PYCR3 mRNA | CTD | PMID:34813904 | finasteride | increases expression | ISO | Pycr3 (Rattus norvegicus) | 6480464 | Finasteride results in increased expression of PYCR3 mRNA | CTD | PMID:24136188 | folic acid | decreases expression | ISO | Pycr3 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of PYCR3 mRNA | CTD | PMID:25629700 | formaldehyde | decreases expression | EXP | | 6480464 | Formaldehyde results in decreased expression of PYCR3 mRNA | CTD | PMID:23649840 | gentamycin | decreases expression | ISO | Pycr3 (Rattus norvegicus) | 6480464 | Gentamicins results in decreased expression of PYCR3 mRNA | CTD | PMID:22061828 | hydralazine | multiple interactions | EXP | | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of PYCR3 mRNA | CTD | PMID:17183730 | inulin | multiple interactions | ISO | Pycr3 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of PYCR3 mRNA | CTD | PMID:36331819 | iron dichloride | decreases expression | EXP | | 6480464 | ferrous chloride results in decreased expression of PYCR3 mRNA | CTD | PMID:35984750 | ivermectin | decreases expression | EXP | | 6480464 | Ivermectin results in decreased expression of PYCR3 protein | CTD | PMID:32959892 | methotrexate | decreases expression | EXP | | 6480464 | Methotrexate results in decreased expression of PYCR3 mRNA | CTD | PMID:17400583 | methyl methanesulfonate | decreases expression | EXP | | 6480464 | Methyl Methanesulfonate results in decreased expression of PYCR3 mRNA | CTD | PMID:23649840 | methylmercury chloride | decreases expression | EXP | | 6480464 | methylmercuric chloride results in decreased expression of PYCR3 mRNA | CTD | PMID:28001369 | paracetamol | affects expression | ISO | Pycr3 (Mus musculus) | 6480464 | Acetaminophen affects the expression of PYCR3 mRNA | CTD | PMID:17562736 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Pycr3 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of PYCR3 mRNA more ... | CTD | PMID:36331819 | selenium atom | multiple interactions | EXP | | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of PYCR3 mRNA | CTD | PMID:19244175 | sodium arsenite | affects expression | EXP | | 6480464 | sodium arsenite affects the expression of PYCR3 mRNA | CTD | PMID:34032870 | sunitinib | decreases expression | EXP | | 6480464 | Sunitinib results in decreased expression of PYCR3 mRNA | CTD | PMID:31533062 | tetrachloromethane | multiple interactions | ISO | Pycr3 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of PYCR3 mRNA] | CTD | PMID:31150632 | tetrachloromethane | decreases expression | ISO | Pycr3 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in decreased expression of PYCR3 mRNA | CTD | PMID:31150632 | titanium dioxide | decreases expression | ISO | Pycr3 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of PYCR3 mRNA | CTD | PMID:29264374 | trimellitic anhydride | increases expression | ISO | Pycr3 (Mus musculus) | 6480464 | trimellitic anhydride results in increased expression of PYCR3 mRNA | CTD | PMID:19042947 | triphenyl phosphate | increases expression | ISO | Pycr3 (Rattus norvegicus) | 6480464 | triphenyl phosphate results in increased expression of PYCR3 mRNA | CTD | PMID:30589522 | urethane | decreases expression | EXP | | 6480464 | Urethane results in decreased expression of PYCR3 mRNA | CTD | PMID:28818685 | valproic acid | increases methylation | EXP | | 6480464 | Valproic Acid results in increased methylation of PYCR3 gene | CTD | PMID:29154799 | valproic acid | multiple interactions | EXP | | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of PYCR3 mRNA | CTD | PMID:17183730 | vitamin E | multiple interactions | EXP | | 6480464 | [Selenium co-treated with Vitamin E] results in decreased expression of PYCR3 mRNA | CTD | PMID:19244175 | vitamin E | decreases expression | EXP | | 6480464 | Vitamin E results in decreased expression of PYCR3 mRNA | CTD | PMID:19244175 | |