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Gene: MX1 (MX dynamin like GTPase 1) Homo sapiens
Symbol: MX1
Name: MX dynamin like GTPase 1
Description: Exhibits identical protein binding activity. Involved in defense response to virus and negative regulation of viral genome replication. Localizes to cytosol; nuclear membrane; and perinuclear region of cytoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: IFI-78K; IFI78; interferon inducible protein p78; interferon-induced GTP-binding protein Mx1; interferon-induced protein p78; interferon-inducible protein p78; interferon-regulated resistance GTP-binding protein MxA; lncMX1-215; MX; MX dynamin-like GTPase 1; MxA; myxoma resistance protein 1; myxovirus (influenza virus) resistance 1, interferon-inducible protein p78; myxovirus resistance protein 1
Mus musculus (house mouse) : Mx2 (MX dynamin-like GTPase 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mx2 (MX dynamin like GTPase 2)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : MX1 (MX dynamin like GTPase 1)
Canis lupus familiaris (dog) : MX1 (MX dynamin like GTPase 1)
Sus scrofa (pig) : MX1 (MX dynamin like GTPase 1)
Chlorocebus sabaeus (African green monkey) : MX1 (MX dynamin like GTPase 1)
more info ...
Related Pseudogenes: AC006499.3   AC006499.5   AC006499.7  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2141,420,304 - 41,459,214 (+)EnsemblGRCh38hg38GRCh38
GRCh382141,420,329 - 41,459,214 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372142,792,520 - 42,831,141 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362141,720,024 - 41,753,008 (+)NCBINCBI36hg18NCBI36
Build 342141,720,023 - 41,753,008NCBI
Celera2127,990,716 - 28,029,320 (+)NCBI
Cytogenetic Map21q22.3NCBI
HuRef2128,261,373 - 28,300,013 (+)NCBIHuRef
CHM1_12142,353,274 - 42,391,928 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on MX1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1353561
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.