MAPK9 (mitogen-activated protein kinase 9) - Rat Genome Database
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Gene: MAPK9 (mitogen-activated protein kinase 9) Homo sapiens
Analyze
Symbol: MAPK9
Name: mitogen-activated protein kinase 9
RGD ID: 736023
HGNC Page HGNC
Description: Exhibits JUN kinase activity and transcription factor binding activity. Involved in several processes, including JNK cascade; cellular response to cadmium ion; and positive regulation of macrophage derived foam cell differentiation. Predicted to localize to cytosol and nucleoplasm. Implicated in colorectal cancer; pancreatic adenocarcinoma; and type 2 diabetes mellitus. Biomarker of Alzheimer's disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: c-Jun kinase 2; c-Jun N-terminal kinase 2; JNK-55; JNK2; JNK2A; JNK2ALPHA; JNK2B; JNK2BETA; Jun kinase; MAP kinase 9; MAPK 9; p54a; p54aSAPK; PRKM9; SAPK; SAPK1a; stress activated protein kinase alpha ii; stress-activated protein kinase 1a; stress-activated protein kinase JNK2
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl5180,233,143 - 180,292,099 (-)EnsemblGRCh38hg38GRCh38
GRCh385180,233,143 - 180,292,083 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh375179,660,143 - 179,719,083 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365179,595,390 - 179,640,216 (-)NCBINCBI36hg18NCBI36
Build 345179,595,389 - 179,640,216NCBI
Celera5175,286,573 - 175,345,058 (-)NCBI
Cytogenetic Map5q35.3NCBI
HuRef5174,385,878 - 174,444,273 (-)NCBIHuRef
CHM1_15179,092,988 - 179,151,485 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-alpha-tocopherol  (EXP)
(+)-alpha-viniferin  (ISO)
(-)-anisomycin  (EXP,ISO)
(-)-citrinin  (EXP)
(-)-epigallocatechin 3-gallate  (EXP)
(R)-noradrenaline  (ISO)
(S)-colchicine  (EXP)
(S)-naringenin  (EXP)
(S)-nicotine  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP,ISO)
1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose  (ISO)
1,2-dimethylhydrazine  (ISO)
1,3-dichloropropan-2-ol  (ISO)
1,4-phenylenediamine  (EXP)
1,8-cineole  (EXP)
1-fluoro-2,4-dinitrobenzene  (EXP)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (EXP)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2-methyl-6-(phenylethynyl)pyridine  (ISO)
3,3',5,5'-tetrabromobisphenol A  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-phenylprop-2-enal  (ISO)
4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid  (ISO)
4-hydroxynon-2-enal  (EXP)
4-hydroxyphenyl retinamide  (EXP)
4-nonylphenol  (ISO)
4-phenylbutyric acid  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
acetaldehyde  (EXP,ISO)
acrylamide  (ISO)
ADP  (EXP)
afimoxifene  (EXP)
aflatoxin B1  (EXP)
aflatoxin B2  (EXP)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
alpha-Chaconine  (ISO)
alpha-mangostin  (EXP)
amidotrizoic acid  (EXP)
amiloride  (ISO)
amino acid  (ISO)
ammonium chloride  (ISO)
aniline  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP,ISO)
antirheumatic drug  (EXP)
apigenin  (ISO)
apocynin  (EXP)
Aroclor 1254  (ISO)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
arsenic trichloride  (EXP,ISO)
arsenite(3-)  (EXP,ISO)
arsenous acid  (EXP,ISO)
Azaspiracid  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (EXP)
beta-hexachlorocyclohexane  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (ISO)
Bisphenol A diglycidyl ether  (ISO)
bortezomib  (EXP)
bufalin  (EXP)
buspirone  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
cadmium sulfate  (ISO)
calcidiol  (ISO)
calix[6]arene  (EXP)
camptothecin  (EXP)
cantharidic acid  (EXP)
capsaicin  (EXP)
carbon nanotube  (ISO)
carnosic acid  (ISO)
chenodeoxycholic acid  (EXP,ISO)
chlorpyrifos  (ISO)
choline  (ISO)
chromium atom  (ISO)
chromium(6+)  (EXP,ISO)
chromones  (EXP)
cisplatin  (EXP,ISO)
clofibric acid  (ISO)
clozapine  (ISO)
cobalt dichloride  (EXP,ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) sulfate  (EXP)
crocidolite asbestos  (EXP)
curcumin  (EXP,ISO)
cyclophosphamide  (ISO)
cyclosporin A  (EXP)
cypermethrin  (ISO)
D-glucose  (ISO)
DDT  (EXP)
deoxycholic acid  (EXP)
Deoxycorticosterone acetate  (ISO)
deoxynivalenol  (EXP,ISO)
desferrioxamine B  (EXP)
dexamethasone  (ISO)
diarsenic trioxide  (EXP,ISO)
dibenziodolium  (EXP)
dichromium trioxide  (EXP)
dicoumarol  (EXP)
dioscin  (EXP)
dioxygen  (EXP,ISO)
diquat  (ISO)
disodium selenite  (EXP,ISO)
disulfiram  (EXP,ISO)
dobutamine  (ISO)
donepezil hydrochloride  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
ebselen  (ISO)
elemental selenium  (EXP)
ellagic acid  (EXP)
emetine  (ISO)
enalapril  (ISO)
enzyme inhibitor  (EXP)
esculetin  (EXP)
Estragole  (ISO)
ethanol  (EXP,ISO)
ethylene glycol bis(2-aminoethyl)tetraacetic acid  (EXP,ISO)
Evodiamine  (EXP)
ferrosoferric oxide  (EXP)
fluorescein 5-isothiocyanate  (EXP)
folic acid  (ISO)
fomepizole  (ISO)
formaldehyde  (EXP)
formoterol fumarate  (ISO)
gallic acid  (EXP)
gamma-hexachlorocyclohexane  (ISO)
Geniposide pentaacetate  (ISO)
ginsenoside Rg1  (EXP)
glucose  (ISO)
glutathione  (ISO)
glycochenodeoxycholic acid  (EXP)
glycocholic acid  (EXP)
glycodeoxycholic acid  (EXP)
GW 4064  (EXP,ISO)
haloperidol  (ISO)
hemin  (ISO)
hesperidin  (EXP)
hexadecanoic acid  (EXP,ISO)
hexamethylene diisocyanate  (EXP)
homocysteine  (EXP)
hydrogen peroxide  (EXP,ISO)
hydrogen sulfide  (ISO)
hypochlorous acid  (EXP)
ICI 118551  (ISO)
indoxyl sulfate  (ISO)
iomeprol  (EXP)
kaempferol  (EXP)
L-ascorbic acid  (EXP)
L-cysteine  (ISO)
L-methionine  (ISO)
lead diacetate  (EXP,ISO)
lead(0)  (EXP)
lead(2+)  (EXP)
lead(II) chloride  (EXP)
lipopolysaccharide  (EXP,ISO)
lithium atom  (ISO)
lithium hydride  (ISO)
Longikaurin A  (EXP)
lovastatin  (ISO)
luteolin  (EXP)
LY294002  (EXP,ISO)
Magnolol  (ISO)
Malonoben  (EXP)
manganese atom  (EXP)
manganese(0)  (EXP)
manganese(II) chloride  (EXP)
mangiferin  (ISO)
Manumycin A  (ISO)
masoprocol  (EXP)
mebendazole  (EXP)
mechlorethamine  (ISO)
melatonin  (EXP)
mercury dichloride  (ISO)
metformin  (EXP)
methotrexate  (EXP,ISO)
Methylazoxymethanol acetate  (ISO)
methylglyoxal  (EXP)
methylmercury chloride  (ISO)
methylseleninic acid  (EXP)
microcystin-LR  (EXP,ISO)
mycophenolic acid  (EXP,ISO)
myricetin  (ISO)
N(6),N(6)-dimethyladenine  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-acetylsphingosine  (EXP,ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-methyl-4-phenylpyridinium  (EXP,ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (EXP)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
naringin  (ISO)
nickel dichloride  (ISO)
nickel sulfate  (EXP)
niclosamide  (ISO)
nicotine  (ISO)
nimesulide  (ISO)
nitroprusside  (ISO)
nocodazole  (EXP)
notoginsenoside R1  (ISO)
ochratoxin A  (EXP)
olmesartan  (ISO)
osthole  (EXP)
oxidopamine  (EXP,ISO)
ozone  (EXP)
paclitaxel  (EXP,ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
parthenolide  (EXP)
PCB138  (EXP)
Pentoxifylline  (EXP)
phenylephrine  (ISO)
phlorizin  (ISO)
phorbol 13-acetate 12-myristate  (EXP,ISO)
phorone  (ISO)
phosgene  (ISO)
phthalic anhydride  (EXP)
platycodin D  (EXP)
poly(I:C)  (ISO)
potassium chloride  (ISO)
pramipexole  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
proanthocyanidin  (ISO)
prodigiosin  (EXP)
progesterone  (ISO)
prostaglandin F2alpha  (ISO)
protein kinase inhibitor  (EXP,ISO)
pterostilbene  (EXP)
puerarin  (EXP)
pyrrolidine dithiocarbamate  (EXP,ISO)
quercetin  (EXP)
reactive oxygen species  (EXP)
resiniferatoxin  (EXP)
resveratrol  (EXP,ISO)
Ro 31-8220  (ISO)
rosmarinic acid  (ISO)
rotenone  (EXP,ISO)
rottlerin  (EXP)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP)
salubrinal  (EXP,ISO)
sanguinarine  (EXP)
SB 203580  (EXP)
selenium atom  (EXP)
serpentine asbestos  (EXP)
silibinin  (EXP)
silicon dioxide  (EXP,ISO)
silver atom  (ISO)
silver(0)  (ISO)
simvastatin  (ISO)
sodium arsenate  (EXP)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
sorafenib  (EXP)
SR 144528  (ISO)
stattic  (EXP)
streptozocin  (EXP,ISO)
sucrose  (EXP)
sulfasalazine  (ISO)
sulfates  (EXP)
sulforaphane  (EXP)
sunitinib  (EXP)
tamoxifen  (EXP,ISO)
Tanshinone I  (ISO)
taurine  (ISO)
taurocholic acid  (ISO)
tert-butyl hydroperoxide  (EXP,ISO)
tetracaine  (ISO)
tetrachloromethane  (ISO)
tetramethylpyrazine  (EXP)
thapsigargin  (ISO)
thimerosal  (EXP)
titanium dioxide  (EXP)
tofacitinib  (EXP)
trichloroethene  (ISO)
trichostatin A  (EXP)
triclosan  (EXP)
trifluoperazine  (EXP,ISO)
trimellitic anhydride  (EXP)
trimethyltin  (ISO)
tunicamycin  (ISO)
tyrphostin AG 1478  (EXP)
ursolic acid  (ISO)
valproic acid  (EXP,ISO)
vincaleukoblastine  (EXP)
vinclozolin  (ISO)
vitamin E  (EXP)
WIN 55212-2  (EXP)
wogonin  (ISO)
wortmannin  (ISO)
zinc acetate  (ISO)
zinc atom  (ISO)
zinc dichloride  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
cellular hyperosmotic response  (ISO)
cellular response to amyloid-beta  (ISO)
cellular response to cadmium ion  (IMP)
cellular response to growth factor stimulus  (ISO)
cellular response to interleukin-1  (ISO)
cellular response to lipopolysaccharide  (ISO)
cellular response to reactive oxygen species  (IMP)
cellular response to tumor necrosis factor  (ISO)
cellular response to UV  (ISO)
central nervous system development  (ISO)
Fc-epsilon receptor signaling pathway  (TAS)
intracellular signal transduction  (IBA)
JNK cascade  (IBA,IDA,ISO,TAS)
JUN phosphorylation  (IEA,ISO)
MAPK cascade  (IEA)
neuron development  (ISO)
neuron projection development  (ISO)
peptidyl-serine phosphorylation  (IDA,ISO)
phosphorylation  (IEA)
positive regulation of apoptotic process  (ISO)
positive regulation of apoptotic signaling pathway  (IEA,ISO)
positive regulation of cell morphogenesis involved in differentiation  (ISO)
positive regulation of chemokine production  (ISO)
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process  (ISO)
positive regulation of gene expression  (IMP)
positive regulation of macrophage derived foam cell differentiation  (IMP)
positive regulation of nitric oxide biosynthetic process  (ISO)
positive regulation of nitric-oxide synthase biosynthetic process  (ISO)
positive regulation of podosome assembly  (IEA,ISO)
positive regulation of prostaglandin biosynthetic process  (ISO)
positive regulation of prostaglandin secretion  (ISO)
positive regulation of protein phosphorylation  (ISO)
positive regulation of protein ubiquitination  (IEA,ISO)
positive regulation of transcription factor catabolic process  (IEA,ISO)
positive regulation of transcription, DNA-templated  (ISO)
protein localization to tricellular tight junction  (IEA,ISO)
protein phosphorylation  (IEA,IMP,ISO)
protein targeting to mitochondrion  (ISO)
regulation of circadian rhythm  (ISO,ISS)
regulation of DNA-binding transcription factor activity  (TAS)
regulation of JNK cascade  (ISO)
regulation of protein ubiquitination  (ISO)
release of cytochrome c from mitochondria  (ISO)
response to amine  (ISO)
response to cadmium ion  (ISO)
response to drug  (ISO)
response to mechanical stimulus  (ISO)
response to nerve growth factor  (ISO)
response to organic substance  (ISO)
response to toxic substance  (ISO)
response to water deprivation  (ISO)
rhythmic process  (IEA)

Cellular Component
cytoplasm  (IBA,ISO)
cytosol  (ISO,TAS)
mitochondrion  (IEA,ISO)
neuron projection  (ISO)
nucleoplasm  (TAS)
nucleus  (IBA,ISO)
perikaryon  (ISO)

References

Additional References at PubMed
PMID:602896   PMID:1602151   PMID:7642542   PMID:7737129   PMID:7969172   PMID:8001819   PMID:8548291   PMID:8626452   PMID:8649858   PMID:8654373   PMID:8846788   PMID:8945519  
PMID:8985011   PMID:9019171   PMID:9045910   PMID:9130707   PMID:9155018   PMID:9374467   PMID:9393873   PMID:9403476   PMID:9405416   PMID:9596579   PMID:9628874   PMID:9732264  
PMID:9733513   PMID:10376527   PMID:10381549   PMID:10383391   PMID:10471813   PMID:10490605   PMID:10490659   PMID:10523642   PMID:10629060   PMID:10669748   PMID:10797012   PMID:10811224  
PMID:10878576   PMID:11024282   PMID:11042694   PMID:11057897   PMID:11062067   PMID:11172026   PMID:11278395   PMID:11278789   PMID:11279232   PMID:11359773   PMID:11468147   PMID:11504923  
PMID:11527157   PMID:11566021   PMID:11602244   PMID:11698270   PMID:11749722   PMID:11865055   PMID:11948398   PMID:11959861   PMID:12023963   PMID:12089333   PMID:12110590   PMID:12151396  
PMID:12167088   PMID:12171600   PMID:12189133   PMID:12225289   PMID:12228228   PMID:12239168   PMID:12384512   PMID:12417588   PMID:12477932   PMID:12538493   PMID:12714584   PMID:12743126  
PMID:12775419   PMID:12788955   PMID:12818176   PMID:12821118   PMID:12857973   PMID:12960231   PMID:14504284   PMID:14581471   PMID:14724588   PMID:15158451   PMID:15184502   PMID:15228592  
PMID:15246824   PMID:15262983   PMID:15276183   PMID:15326485   PMID:15474087   PMID:15489334   PMID:15527495   PMID:15603708   PMID:15629715   PMID:15637069   PMID:15655348   PMID:15693750  
PMID:15778501   PMID:15860507   PMID:15911620   PMID:15958558   PMID:15998799   PMID:16169070   PMID:16189514   PMID:16288922   PMID:16381010   PMID:16412424   PMID:16481105   PMID:16533805  
PMID:16552729   PMID:16611996   PMID:16824735   PMID:17074809   PMID:17189706   PMID:17192257   PMID:17296730   PMID:17397142   PMID:17637567   PMID:17785791   PMID:17875713   PMID:17906291  
PMID:17908987   PMID:18262097   PMID:18423204   PMID:18439101   PMID:18586006   PMID:18612143   PMID:18667537   PMID:18801372   PMID:18838864   PMID:18940813   PMID:18950845   PMID:19060904  
PMID:19093167   PMID:19097143   PMID:19153595   PMID:19154785   PMID:19204086   PMID:19339050   PMID:19385049   PMID:19527717   PMID:19567513   PMID:19589256   PMID:19591174   PMID:19596001  
PMID:19620725   PMID:19651615   PMID:19667122   PMID:19806201   PMID:19864026   PMID:19906316   PMID:19910486   PMID:19913278   PMID:19996270   PMID:20056178   PMID:20174665   PMID:20186153  
PMID:20354187   PMID:20379614   PMID:20432452   PMID:20483637   PMID:20525557   PMID:20595622   PMID:20871632   PMID:20936779   PMID:21110917   PMID:21357683   PMID:21364637   PMID:21384452  
PMID:21504622   PMID:21516116   PMID:21572099   PMID:21629969   PMID:21749326   PMID:21856198   PMID:21873635   PMID:21900206   PMID:21930785   PMID:21988832   PMID:22105759   PMID:22217202  
PMID:22366412   PMID:22441692   PMID:22617334   PMID:22689214   PMID:22730327   PMID:22748923   PMID:22910906   PMID:22939629   PMID:23045269   PMID:23071284   PMID:23171849   PMID:23273084  
PMID:23341463   PMID:23515281   PMID:23602568   PMID:23615449   PMID:23900581   PMID:23912840   PMID:24127566   PMID:24335928   PMID:24418364   PMID:24447338   PMID:24556843   PMID:24608675  
PMID:24658140   PMID:24704364   PMID:24722904   PMID:24735948   PMID:24740539   PMID:24802394   PMID:24906853   PMID:24947996   PMID:25077544   PMID:25241761   PMID:25402006   PMID:25416956  
PMID:25423287   PMID:25456131   PMID:25609649   PMID:25776267   PMID:25792289   PMID:25943894   PMID:26186194   PMID:26235742   PMID:26344197   PMID:26503828   PMID:26514923   PMID:26638075  
PMID:26708719   PMID:26867034   PMID:27432908   PMID:27440420   PMID:27494776   PMID:27503909   PMID:27761579   PMID:27880917   PMID:28062184   PMID:28089251   PMID:28383667   PMID:28514442  
PMID:28675297   PMID:28846829   PMID:29117863   PMID:29360953   PMID:29598867   PMID:29676528   PMID:29766567   PMID:29863427   PMID:29892012   PMID:30119172   PMID:30190325   PMID:30591109  
PMID:31063355   PMID:31089135   PMID:31091453   PMID:31149782   PMID:31515488   PMID:32296183  


Genomics

Comparative Map Data
MAPK9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl5180,233,143 - 180,292,099 (-)EnsemblGRCh38hg38GRCh38
GRCh385180,233,143 - 180,292,083 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh375179,660,143 - 179,719,083 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365179,595,390 - 179,640,216 (-)NCBINCBI36hg18NCBI36
Build 345179,595,389 - 179,640,216NCBI
Celera5175,286,573 - 175,345,058 (-)NCBI
Cytogenetic Map5q35.3NCBI
HuRef5174,385,878 - 174,444,273 (-)NCBIHuRef
CHM1_15179,092,988 - 179,151,485 (-)NCBICHM1_1
Mapk9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391149,737,558 - 49,777,248 (+)NCBIGRCm39mm39
GRCm39 Ensembl1149,737,578 - 49,777,248 (+)Ensembl
GRCm381149,846,728 - 49,886,421 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1149,846,751 - 49,886,421 (+)EnsemblGRCm38mm10GRCm38
MGSCv371149,660,253 - 49,699,923 (+)NCBIGRCm37mm9NCBIm37
MGSCv361149,690,177 - 49,729,521 (+)NCBImm8
Celera1154,408,836 - 54,448,385 (+)NCBICelera
Cytogenetic Map11B1.2NCBI
Mapk9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21034,169,661 - 34,211,138 (+)NCBI
Rnor_6.0 Ensembl1035,333,859 - 35,374,355 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01035,333,859 - 35,374,364 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01035,105,633 - 35,147,516 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41035,353,486 - 35,384,319 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11035,354,534 - 35,385,368 (+)NCBI
Celera1033,525,368 - 33,565,857 (+)NCBICelera
Cytogenetic Map10q21NCBI
Mapk9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955408391,094 - 430,981 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955408391,094 - 430,638 (+)NCBIChiLan1.0ChiLan1.0
MAPK9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.15182,748,381 - 182,801,464 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5182,748,381 - 182,795,135 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v05175,437,167 - 175,495,469 (-)NCBIMhudiblu_PPA_v0panPan3
MAPK9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl111,443,547 - 1,478,119 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1111,443,528 - 1,480,501 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Mapk9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936739551,678 - 602,027 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAPK9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl278,338,369 - 78,399,105 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1278,338,466 - 78,399,108 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2279,823,618 - 79,884,343 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MAPK9
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12381,965,330 - 82,026,414 (-)NCBI
ChlSab1.1 Ensembl2381,963,899 - 82,013,659 (-)Ensembl
Mapk9
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473342,998,948 - 43,048,392 (-)NCBI

Position Markers
RH15681  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375179,660,610 - 179,660,806UniSTSGRCh37
Build 365179,593,216 - 179,593,412RGDNCBI36
Celera5175,286,589 - 175,286,785RGD
Cytogenetic Map5q35UniSTS
HuRef5174,385,894 - 174,386,090UniSTS
RH80226  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375179,663,156 - 179,663,354UniSTSGRCh37
Build 365179,595,762 - 179,595,960RGDNCBI36
Celera5175,289,135 - 175,289,333RGD
Cytogenetic Map5q35UniSTS
HuRef5174,388,440 - 174,388,638UniSTS
GeneMap99-GB4 RH Map5651.83UniSTS
RH122211  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375179,669,421 - 179,669,695UniSTSGRCh37
Build 365179,602,027 - 179,602,301RGDNCBI36
Celera5175,295,400 - 175,295,674RGD
Cytogenetic Map5q35UniSTS
HuRef5174,394,701 - 174,394,975UniSTS
TNG Radiation Hybrid Map584268.0UniSTS
D5S445E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375179,662,038 - 179,662,129UniSTSGRCh37
Build 365179,594,644 - 179,594,735RGDNCBI36
Celera5175,288,017 - 175,288,108RGD
Cytogenetic Map5q35UniSTS
HuRef5174,387,322 - 174,387,413UniSTS
D5S1584E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375179,661,899 - 179,662,004UniSTSGRCh37
Build 365179,594,505 - 179,594,610RGDNCBI36
Celera5175,287,878 - 175,287,983RGD
Cytogenetic Map5q35UniSTS
HuRef5174,387,183 - 174,387,288UniSTS
SHGC-112628  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375179,669,073 - 179,669,262UniSTSGRCh37
Build 365179,601,679 - 179,601,868RGDNCBI36
Celera5175,295,052 - 175,295,241RGD
Cytogenetic Map5q35UniSTS
HuRef5174,394,353 - 174,394,542UniSTS
TNG Radiation Hybrid Map584251.0UniSTS
SHGC-146334  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375179,716,145 - 179,716,471UniSTSGRCh37
Build 365179,648,751 - 179,649,077RGDNCBI36
Celera5175,342,133 - 175,342,459RGD
Cytogenetic Map5q35UniSTS
HuRef5174,441,508 - 174,441,834UniSTS
TNG Radiation Hybrid Map584296.0UniSTS
SHGC-147181  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375179,715,566 - 179,715,840UniSTSGRCh37
Build 365179,648,172 - 179,648,446RGDNCBI36
Celera5175,341,554 - 175,341,828RGD
Cytogenetic Map5q35UniSTS
HuRef5174,440,929 - 174,441,203UniSTS
TNG Radiation Hybrid Map584288.0UniSTS
SHGC-80682  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375179,691,668 - 179,691,987UniSTSGRCh37
Build 365179,624,274 - 179,624,593RGDNCBI36
Celera5175,317,660 - 175,317,979RGD
Cytogenetic Map5q35UniSTS
HuRef5174,417,009 - 174,417,328UniSTS
TNG Radiation Hybrid Map584280.0UniSTS
MAPK9_2236  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375179,662,611 - 179,663,380UniSTSGRCh37
Build 365179,595,217 - 179,595,986RGDNCBI36
Celera5175,288,590 - 175,289,359RGD
HuRef5174,387,895 - 174,388,664UniSTS
1806  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375179,662,044 - 179,662,174UniSTSGRCh37
Build 365179,594,650 - 179,594,780RGDNCBI36
Celera5175,288,023 - 175,288,153RGD
Cytogenetic Map5q35UniSTS
HuRef5174,387,328 - 174,387,458UniSTS
GeneMap99-GB4 RH Map5645.92UniSTS
D5S1618E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375179,660,719 - 179,660,795UniSTSGRCh37
Build 365179,593,325 - 179,593,401RGDNCBI36
Celera5175,286,698 - 175,286,774RGD
Cytogenetic Map5q35UniSTS
HuRef5174,386,003 - 174,386,080UniSTS
GeneMap99-GB4 RH Map5650.3UniSTS
RH36378  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375179,662,277 - 179,662,382UniSTSGRCh37
Build 365179,594,883 - 179,594,988RGDNCBI36
Celera5175,288,256 - 175,288,361RGD
Cytogenetic Map5q35UniSTS
HuRef5174,387,561 - 174,387,666UniSTS
GeneMap99-GB4 RH Map5650.3UniSTS
D5S2449  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375179,702,656 - 179,702,891UniSTSGRCh37
Build 365179,635,262 - 179,635,497RGDNCBI36
Celera5175,328,647 - 175,328,882RGD
Cytogenetic Map5q35UniSTS
HuRef5174,427,996 - 174,428,231UniSTS
Whitehead-RH Map5545.1UniSTS
Whitehead-YAC Contig Map5 UniSTS

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
MIR93hsa-miR-93-5pMirtarbaseexternal_infoLuciferase reporter assayNon-Functional MTI20065103
MIR199A1hsa-miR-199a-3pMirtarbaseexternal_infoWestern blotNon-Functional MTI18456660
MIR17hsa-miR-17-5pMirtarbaseexternal_infoqRT-PCR//Luciferase reporter assay//Western blotFunctional MTI18700987
MIR17hsa-miR-17-5pMirtarbaseexternal_infoLuciferase reporter assayNon-Functional MTI21283765
MIR141hsa-miR-141-3pMirtarbaseexternal_infoWestern blotFunctional MTI20053927

Predicted Target Of
Summary Value
Count of predictions:7066
Count of miRNA genes:1244
Interacting mature miRNAs:1565
Transcripts:ENST00000343111, ENST00000347470, ENST00000393360, ENST00000393362, ENST00000397072, ENST00000425491, ENST00000452135, ENST00000455781, ENST00000520212, ENST00000523135, ENST00000523583, ENST00000524170, ENST00000539014
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 1965 1588 1272 196 950 90 3053 1563 3275 264 1239 1543 119 964 2061 4 2
Low 474 1388 454 428 987 375 1303 633 459 155 221 70 56 1 240 727 2
Below cutoff 15 14 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_029059 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001135044 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001308244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001364607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001364608 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001364609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001364610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001364611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001364612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001364613 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_002752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_139068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_139069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_139070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005265940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017009642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017009643 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB451302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB451355 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB451433 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC008610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC104115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK289638 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC032539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF056535 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ025589 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471165 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR536580 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CX758487 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DB451562 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ066599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU927388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM036706 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM036707 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM036708 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM036709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L31951 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U09759 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U34821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U35002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U35003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000343111   ⟹   ENSP00000345524
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5180,233,594 - 180,292,099 (-)Ensembl
RefSeq Acc Id: ENST00000347470   ⟹   ENSP00000321410
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5180,236,187 - 180,292,092 (-)Ensembl
RefSeq Acc Id: ENST00000393360   ⟹   ENSP00000377028
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5180,233,594 - 180,292,056 (-)Ensembl
RefSeq Acc Id: ENST00000393362   ⟹   ENSP00000377029
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5180,242,578 - 180,292,037 (-)Ensembl
RefSeq Acc Id: ENST00000397072   ⟹   ENSP00000380262
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5180,238,309 - 180,280,581 (-)Ensembl
RefSeq Acc Id: ENST00000425491   ⟹   ENSP00000397422
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5180,246,028 - 180,291,967 (-)Ensembl
RefSeq Acc Id: ENST00000452135   ⟹   ENSP00000394560
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5180,233,143 - 180,292,099 (-)Ensembl
RefSeq Acc Id: ENST00000455781   ⟹   ENSP00000389338
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5180,233,594 - 180,292,071 (-)Ensembl
RefSeq Acc Id: ENST00000520212
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5180,236,526 - 180,242,900 (-)Ensembl
RefSeq Acc Id: ENST00000523135
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5180,253,507 - 180,264,842 (-)Ensembl
RefSeq Acc Id: ENST00000523583   ⟹   ENSP00000430608
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5180,264,781 - 180,292,053 (-)Ensembl
RefSeq Acc Id: ENST00000524170
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5180,242,728 - 180,263,089 (-)Ensembl
RefSeq Acc Id: ENST00000539014   ⟹   ENSP00000443149
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl5180,246,545 - 180,280,581 (-)Ensembl
RefSeq Acc Id: NM_001135044   ⟹   NP_001128516
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385180,246,020 - 180,292,083 (-)NCBI
GRCh375179,660,594 - 179,719,071 (-)ENTREZGENE
HuRef5174,385,878 - 174,444,273 (-)ENTREZGENE
CHM1_15179,105,419 - 179,151,485 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001308244   ⟹   NP_001295173
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385180,246,020 - 180,280,608 (-)NCBI
CHM1_15179,105,411 - 179,140,030 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001364607   ⟹   NP_001351536
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385180,233,594 - 180,292,083 (-)NCBI
RefSeq Acc Id: NM_001364608   ⟹   NP_001351537
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385180,233,143 - 180,292,083 (-)NCBI
RefSeq Acc Id: NM_001364609   ⟹   NP_001351538
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385180,233,143 - 180,292,083 (-)NCBI
RefSeq Acc Id: NM_001364610   ⟹   NP_001351539
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385180,246,020 - 180,292,083 (-)NCBI
RefSeq Acc Id: NM_001364611   ⟹   NP_001351540
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385180,233,143 - 180,292,083 (-)NCBI
RefSeq Acc Id: NM_001364612   ⟹   NP_001351541
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385180,233,143 - 180,291,275 (-)NCBI
RefSeq Acc Id: NM_001364613   ⟹   NP_001351542
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385180,233,143 - 180,292,083 (-)NCBI
RefSeq Acc Id: NM_002752   ⟹   NP_002743
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385180,233,143 - 180,292,083 (-)NCBI
GRCh375179,660,594 - 179,719,071 (-)ENTREZGENE
Build 365179,595,390 - 179,640,216 (-)NCBI Archive
HuRef5174,385,878 - 174,444,273 (-)ENTREZGENE
CHM1_15179,092,988 - 179,151,485 (-)NCBI
Sequence:
RefSeq Acc Id: NM_139068   ⟹   NP_620707
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385180,233,594 - 180,292,083 (-)NCBI
GRCh375179,660,594 - 179,719,071 (-)ENTREZGENE
Build 365179,595,390 - 179,640,216 (-)NCBI Archive
HuRef5174,385,878 - 174,444,273 (-)ENTREZGENE
CHM1_15179,092,988 - 179,151,485 (-)NCBI
Sequence:
RefSeq Acc Id: NM_139069   ⟹   NP_620708
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385180,233,594 - 180,292,083 (-)NCBI
GRCh375179,660,594 - 179,719,071 (-)ENTREZGENE
Build 365179,595,390 - 179,640,216 (-)NCBI Archive
HuRef5174,385,878 - 174,444,273 (-)ENTREZGENE
CHM1_15179,092,988 - 179,151,485 (-)NCBI
Sequence:
RefSeq Acc Id: NM_139070   ⟹   NP_620709
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385180,233,143 - 180,292,083 (-)NCBI
GRCh375179,660,594 - 179,719,071 (-)ENTREZGENE
Build 365179,595,390 - 179,640,216 (-)NCBI Archive
HuRef5174,385,878 - 174,444,273 (-)ENTREZGENE
CHM1_15179,092,988 - 179,151,485 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005265940   ⟹   XP_005265997
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385180,233,636 - 180,291,963 (-)NCBI
GRCh375179,660,594 - 179,719,071 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017009642   ⟹   XP_016865131
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385180,238,327 - 180,291,967 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017009643   ⟹   XP_016865132
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385180,246,020 - 180,291,967 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001128516 (Get FASTA)   NCBI Sequence Viewer  
  NP_001295173 (Get FASTA)   NCBI Sequence Viewer  
  NP_001351536 (Get FASTA)   NCBI Sequence Viewer  
  NP_001351537 (Get FASTA)   NCBI Sequence Viewer  
  NP_001351538 (Get FASTA)   NCBI Sequence Viewer  
  NP_001351539 (Get FASTA)   NCBI Sequence Viewer  
  NP_001351540 (Get FASTA)   NCBI Sequence Viewer  
  NP_001351541 (Get FASTA)   NCBI Sequence Viewer  
  NP_001351542 (Get FASTA)   NCBI Sequence Viewer  
  NP_002743 (Get FASTA)   NCBI Sequence Viewer  
  NP_620707 (Get FASTA)   NCBI Sequence Viewer  
  NP_620708 (Get FASTA)   NCBI Sequence Viewer  
  NP_620709 (Get FASTA)   NCBI Sequence Viewer  
  XP_005265997 (Get FASTA)   NCBI Sequence Viewer  
  XP_016865131 (Get FASTA)   NCBI Sequence Viewer  
  XP_016865132 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA56831 (Get FASTA)   NCBI Sequence Viewer  
  AAA74740 (Get FASTA)   NCBI Sequence Viewer  
  AAC50606 (Get FASTA)   NCBI Sequence Viewer  
  AAC50608 (Get FASTA)   NCBI Sequence Viewer  
  AAC50609 (Get FASTA)   NCBI Sequence Viewer  
  AAH32539 (Get FASTA)   NCBI Sequence Viewer  
  AAY46156 (Get FASTA)   NCBI Sequence Viewer  
  ACH57450 (Get FASTA)   NCBI Sequence Viewer  
  ADH10365 (Get FASTA)   NCBI Sequence Viewer  
  ADH10366 (Get FASTA)   NCBI Sequence Viewer  
  ADH10367 (Get FASTA)   NCBI Sequence Viewer  
  ADH10368 (Get FASTA)   NCBI Sequence Viewer  
  BAF82327 (Get FASTA)   NCBI Sequence Viewer  
  BAG70116 (Get FASTA)   NCBI Sequence Viewer  
  BAG70169 (Get FASTA)   NCBI Sequence Viewer  
  BAG70247 (Get FASTA)   NCBI Sequence Viewer  
  CAG38817 (Get FASTA)   NCBI Sequence Viewer  
  EAW53757 (Get FASTA)   NCBI Sequence Viewer  
  EAW53758 (Get FASTA)   NCBI Sequence Viewer  
  EAW53759 (Get FASTA)   NCBI Sequence Viewer  
  EAW53760 (Get FASTA)   NCBI Sequence Viewer  
  EAW53761 (Get FASTA)   NCBI Sequence Viewer  
  EAW53762 (Get FASTA)   NCBI Sequence Viewer  
  EAW53763 (Get FASTA)   NCBI Sequence Viewer  
  EAW53764 (Get FASTA)   NCBI Sequence Viewer  
  EAW53765 (Get FASTA)   NCBI Sequence Viewer  
  P45984 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_002743   ⟸   NM_002752
- Peptide Label: isoform alpha2
- UniProtKB: P45984 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_620707   ⟸   NM_139068
- Peptide Label: isoform alpha1
- UniProtKB: P45984 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_620709   ⟸   NM_139070
- Peptide Label: isoform beta2
- UniProtKB: P45984 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_620708   ⟸   NM_139069
- Peptide Label: isoform beta1
- UniProtKB: P45984 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001128516   ⟸   NM_001135044
- Peptide Label: isoform JNK2 gamma
- UniProtKB: P45984 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_005265997   ⟸   XM_005265940
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: NP_001295173   ⟸   NM_001308244
- Peptide Label: isoform gamma2
- UniProtKB: P45984 (UniProtKB/Swiss-Prot),   D7R525 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_016865131   ⟸   XM_017009642
- Peptide Label: isoform X6
- UniProtKB: D7R526 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_016865132   ⟸   XM_017009643
- Peptide Label: isoform X7
- UniProtKB: D7R525 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001351542   ⟸   NM_001364613
- Peptide Label: isoform 12
RefSeq Acc Id: NP_001351537   ⟸   NM_001364608
- Peptide Label: isoform alpha2
RefSeq Acc Id: NP_001351538   ⟸   NM_001364609
- Peptide Label: isoform beta2
RefSeq Acc Id: NP_001351540   ⟸   NM_001364611
- Peptide Label: isoform 11
RefSeq Acc Id: NP_001351541   ⟸   NM_001364612
- Peptide Label: isoform 11
RefSeq Acc Id: NP_001351536   ⟸   NM_001364607
- Peptide Label: isoform alpha1
RefSeq Acc Id: NP_001351539   ⟸   NM_001364610
- Peptide Label: isoform JNK2 gamma
RefSeq Acc Id: ENSP00000397422   ⟸   ENST00000425491
RefSeq Acc Id: ENSP00000321410   ⟸   ENST00000347470
RefSeq Acc Id: ENSP00000394560   ⟸   ENST00000452135
RefSeq Acc Id: ENSP00000389338   ⟸   ENST00000455781
RefSeq Acc Id: ENSP00000430608   ⟸   ENST00000523583
RefSeq Acc Id: ENSP00000443149   ⟸   ENST00000539014
RefSeq Acc Id: ENSP00000377029   ⟸   ENST00000393362
RefSeq Acc Id: ENSP00000377028   ⟸   ENST00000393360
RefSeq Acc Id: ENSP00000345524   ⟸   ENST00000343111
RefSeq Acc Id: ENSP00000380262   ⟸   ENST00000397072
Protein Domains
Protein kinase


Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 5q35.3(chr5:178529878-181269805)x3 copy number gain See cases [RCV000051205] Chr5:178529878..181269805 [GRCh38]
Chr5:177956879..180696806 [GRCh37]
Chr5:177889485..180629412 [NCBI36]
Chr5:5q35.3
uncertain significance
GRCh38/hg38 5q32-35.3(chr5:149714592-181272151)x3 copy number gain See cases [RCV000051863] Chr5:149714592..181272151 [GRCh38]
Chr5:149094155..180699152 [GRCh37]
Chr5:149074348..180631758 [NCBI36]
Chr5:5q32-35.3
pathogenic
GRCh38/hg38 5q33.3-35.3(chr5:160029980-181269805)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051865]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000051865]|See cases [RCV000051865] Chr5:160029980..181269805 [GRCh38]
Chr5:159456987..180696806 [GRCh37]
Chr5:159389565..180629412 [NCBI36]
Chr5:5q33.3-35.3
pathogenic
GRCh38/hg38 5q34-35.3(chr5:168689326-181269946)x3 copy number gain See cases [RCV000051866] Chr5:168689326..181269946 [GRCh38]
Chr5:168116331..180696947 [GRCh37]
Chr5:168048909..180629553 [NCBI36]
Chr5:5q34-35.3
pathogenic
GRCh38/hg38 5q35.2-35.3(chr5:175889986-180793986)x3 copy number gain See cases [RCV000051868] Chr5:175889986..180793986 [GRCh38]
Chr5:175316989..180220986 [GRCh37]
Chr5:175249595..180153592 [NCBI36]
Chr5:5q35.2-35.3
pathogenic
GRCh38/hg38 5q33.3-35.3(chr5:156825512-181269805)x3 copy number gain See cases [RCV000133847] Chr5:156825512..181269805 [GRCh38]
Chr5:156252523..180696806 [GRCh37]
Chr5:156185101..180629412 [NCBI36]
Chr5:5q33.3-35.3
pathogenic
GRCh38/hg38 5q35.3(chr5:179669736-180897169)x1 copy number loss See cases [RCV000135285] Chr5:179669736..180897169 [GRCh38]
Chr5:179096737..180324169 [GRCh37]
Chr5:179029343..180256775 [NCBI36]
Chr5:5q35.3
likely pathogenic
GRCh38/hg38 5q34-35.3(chr5:164386701-181269805)x3 copy number gain See cases [RCV000135546] Chr5:164386701..181269805 [GRCh38]
Chr5:163813707..180696806 [GRCh37]
Chr5:163746285..180629412 [NCBI36]
Chr5:5q34-35.3
pathogenic
GRCh38/hg38 5q35.1-35.3(chr5:169334755-181285301)x3 copy number gain See cases [RCV000141249] Chr5:169334755..181285301 [GRCh38]
Chr5:168761759..180712302 [GRCh37]
Chr5:168694337..180644908 [NCBI36]
Chr5:5q35.1-35.3
pathogenic
GRCh38/hg38 5q35.2-35.3(chr5:175536771-181292788)x1 copy number loss See cases [RCV000141987] Chr5:175536771..181292788 [GRCh38]
Chr5:174963774..180719789 [GRCh37]
Chr5:174896380..180652395 [NCBI36]
Chr5:5q35.2-35.3
pathogenic
GRCh38/hg38 5q35.3(chr5:178235909-181292788)x3 copy number gain See cases [RCV000142298] Chr5:178235909..181292788 [GRCh38]
Chr5:177662910..180719789 [GRCh37]
Chr5:177595516..180652395 [NCBI36]
Chr5:5q35.3
likely pathogenic
GRCh38/hg38 5q35.2-35.3(chr5:176700128-181269805)x1 copy number loss See cases [RCV000142648] Chr5:176700128..181269805 [GRCh38]
Chr5:176127129..180696806 [GRCh37]
Chr5:176059735..180629412 [NCBI36]
Chr5:5q35.2-35.3
pathogenic
GRCh37/hg19 5q35.2-35.3(chr5:174397487-180686444)x1 copy number loss See cases [RCV000167565] Chr5:174397487..180686444 [GRCh37]
Chr5:5q35.2-35.3
pathogenic
Single allele duplication not provided [RCV000768450] Chr5:175843728..180703728 [GRCh37]
Chr5:5q35.2-35.3
likely pathogenic
GRCh37/hg19 5q35.3(chr5:179240402-179751111)x3 copy number gain See cases [RCV000446333] Chr5:179240402..179751111 [GRCh37]
Chr5:5q35.3
uncertain significance
GRCh37/hg19 5q35.3(chr5:179309535-180719789)x3 copy number gain See cases [RCV000447009] Chr5:179309535..180719789 [GRCh37]
Chr5:5q35.3
pathogenic
GRCh37/hg19 5q35.2-35.3(chr5:176274007-180719789)x1 copy number loss See cases [RCV000447018] Chr5:176274007..180719789 [GRCh37]
Chr5:5q35.2-35.3
pathogenic
GRCh37/hg19 5q35.3(chr5:179217944-179694141)x3 copy number gain See cases [RCV000447629] Chr5:179217944..179694141 [GRCh37]
Chr5:5q35.3
uncertain significance
GRCh37/hg19 5p15.33-q35.3(chr5:113577-180719789) copy number gain See cases [RCV000510723] Chr5:113577..180719789 [GRCh37]
Chr5:5p15.33-q35.3
pathogenic
GRCh37/hg19 5q35.3(chr5:178228725-180678091)x3 copy number gain See cases [RCV000448488] Chr5:178228725..180678091 [GRCh37]
Chr5:5q35.3
pathogenic
GRCh37/hg19 5q35.2-35.3(chr5:174427052-180719789)x1 copy number loss See cases [RCV000448611] Chr5:174427052..180719789 [GRCh37]
Chr5:5q35.2-35.3
pathogenic
GRCh37/hg19 5q35.2-35.3(chr5:175601473-180100378)x1 copy number loss See cases [RCV000448793] Chr5:175601473..180100378 [GRCh37]
Chr5:5q35.2-35.3
pathogenic
GRCh37/hg19 5q21.3-35.3(chr5:106716357-180687338)x3 copy number gain See cases [RCV000448245] Chr5:106716357..180687338 [GRCh37]
Chr5:5q21.3-35.3
pathogenic
GRCh37/hg19 5q35.3(chr5:178849756-180719789)x3 copy number gain See cases [RCV000448073] Chr5:178849756..180719789 [GRCh37]
Chr5:5q35.3
uncertain significance
GRCh37/hg19 5q35.3(chr5:179663119-179857751)x3 copy number gain See cases [RCV000447828] Chr5:179663119..179857751 [GRCh37]
Chr5:5q35.3
uncertain significance
GRCh37/hg19 5q35.1-35.3(chr5:171396359-180719789)x3 copy number gain See cases [RCV000448458] Chr5:171396359..180719789 [GRCh37]
Chr5:5q35.1-35.3
pathogenic
GRCh37/hg19 5q35.1-35.3(chr5:172031248-180719789)x3 copy number gain See cases [RCV000512068] Chr5:172031248..180719789 [GRCh37]
Chr5:5q35.1-35.3
pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:113577-180719789)x3 copy number gain See cases [RCV000512039] Chr5:113577..180719789 [GRCh37]
Chr5:5p15.33-q35.3
pathogenic
GRCh37/hg19 5q35.2-35.3(chr5:175570677-180719789)x1 copy number loss See cases [RCV000510785] Chr5:175570677..180719789 [GRCh37]
Chr5:5q35.2-35.3
pathogenic
GRCh37/hg19 5q35.3(chr5:177535168-180719789)x3 copy number gain See cases [RCV000512203] Chr5:177535168..180719789 [GRCh37]
Chr5:5q35.3
uncertain significance
GRCh37/hg19 5q35.3(chr5:179240909-180035580)x3 copy number gain not provided [RCV000682625] Chr5:179240909..180035580 [GRCh37]
Chr5:5q35.3
uncertain significance
GRCh37/hg19 5q35.3(chr5:177114088-180719789)x1 copy number loss not provided [RCV000682620] Chr5:177114088..180719789 [GRCh37]
Chr5:5q35.3
uncertain significance
GRCh37/hg19 5q35.3(chr5:179694142-179799330)x1 copy number loss not provided [RCV000682626] Chr5:179694142..179799330 [GRCh37]
Chr5:5q35.3
uncertain significance
GRCh37/hg19 5p15.33-q35.3(chr5:25328-180693344)x3 copy number gain not provided [RCV000744323] Chr5:25328..180693344 [GRCh37]
Chr5:5p15.33-q35.3
pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:13648-180905029)x3 copy number gain not provided [RCV000744317] Chr5:13648..180905029 [GRCh37]
Chr5:5p15.33-q35.3
pathogenic
GRCh37/hg19 5q33.2-35.3(chr5:155344802-180693344)x3 copy number gain not provided [RCV000745284] Chr5:155344802..180693344 [GRCh37]
Chr5:5q33.2-35.3
pathogenic
GRCh37/hg19 5q35.2-35.3(chr5:174832617-180693344)x3 copy number gain not provided [RCV000745336] Chr5:174832617..180693344 [GRCh37]
Chr5:5q35.2-35.3
pathogenic
GRCh37/hg19 5q35.2-35.3(chr5:174990352-180690937) copy number gain not provided [RCV000767711] Chr5:174990352..180690937 [GRCh37]
Chr5:5q35.2-35.3
pathogenic
GRCh37/hg19 5q35.3(chr5:177776148-180687012) copy number loss not provided [RCV000767663] Chr5:177776148..180687012 [GRCh37]
Chr5:5q35.3
likely pathogenic
GRCh37/hg19 5q35.3(chr5:179606925-179807137)x1 copy number loss Intellectual disability [RCV001250265] Chr5:179606925..179807137 [GRCh37]
Chr5:5q35.3
uncertain significance
GRCh37/hg19 5q35.3(chr5:176848982-180719789)x3 copy number gain not provided [RCV000847220] Chr5:176848982..180719789 [GRCh37]
Chr5:5q35.3
pathogenic
GRCh37/hg19 5q35.3(chr5:178487249-180622216)x4 copy number gain not provided [RCV001005750] Chr5:178487249..180622216 [GRCh37]
Chr5:5q35.3
uncertain significance
GRCh37/hg19 5q35.3(chr5:179479838-180695063)x3 copy number gain not provided [RCV001005751] Chr5:179479838..180695063 [GRCh37]
Chr5:5q35.3
uncertain significance
GRCh37/hg19 5q35.1-35.3(chr5:170805664-180719789)x3 copy number gain 5q35 microduplication syndrome [RCV001263227] Chr5:170805664..180719789 [GRCh37]
Chr5:5q35.1-35.3
pathogenic
GRCh37/hg19 5q35.3(chr5:179528704-179860433)x1 copy number loss not provided [RCV001258716] Chr5:179528704..179860433 [GRCh37]
Chr5:5q35.3
uncertain significance
GRCh37/hg19 5q35.3(chr5:179522222-179952028)x3 copy number gain not provided [RCV001258719] Chr5:179522222..179952028 [GRCh37]
Chr5:5q35.3
uncertain significance

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:6886 AgrOrtholog
COSMIC MAPK9 COSMIC
Ensembl Genes ENSG00000050748 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000321410 UniProtKB/TrEMBL
  ENSP00000345524 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000377028 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000377029 UniProtKB/TrEMBL
  ENSP00000380262 UniProtKB/TrEMBL
  ENSP00000389338 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000394560 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000397422 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000430608 UniProtKB/TrEMBL
  ENSP00000443149 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENST00000343111 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000347470 UniProtKB/TrEMBL
  ENST00000393360 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000393362 UniProtKB/TrEMBL
  ENST00000397072 UniProtKB/TrEMBL
  ENST00000425491 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000452135 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000455781 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000523583 UniProtKB/TrEMBL
  ENST00000539014 ENTREZGENE, UniProtKB/TrEMBL
GTEx ENSG00000050748 GTEx
HGNC ID HGNC:6886 ENTREZGENE
Human Proteome Map MAPK9 Human Proteome Map
InterPro Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MAP_kinase_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MAPK_JNK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:5601 UniProtKB/Swiss-Prot
NCBI Gene 5601 ENTREZGENE
OMIM 602896 OMIM
Pfam Pkinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA30630 PharmGKB
PRINTS JNKMAPKINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE MAPK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART S_TKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B5BUJ7_HUMAN UniProtKB/TrEMBL
  D7R525 ENTREZGENE, UniProtKB/TrEMBL
  D7R526 ENTREZGENE, UniProtKB/TrEMBL
  D7R527_HUMAN UniProtKB/TrEMBL
  D7R528_HUMAN UniProtKB/TrEMBL
  E5RJ57_HUMAN UniProtKB/TrEMBL
  J3KNK1_HUMAN UniProtKB/TrEMBL
  MK09_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary A8K0S3 UniProtKB/Swiss-Prot
  B5BU66 UniProtKB/Swiss-Prot
  B5M0B4 UniProtKB/Swiss-Prot
  D3DWQ8 UniProtKB/Swiss-Prot
  D3DWQ9 UniProtKB/Swiss-Prot
  H7BYK0 UniProtKB/TrEMBL
  Q15708 UniProtKB/Swiss-Prot
  Q15710 UniProtKB/Swiss-Prot
  Q15711 UniProtKB/Swiss-Prot
  Q8N5C5 UniProtKB/Swiss-Prot