KLF6 (Kruppel like factor 6) - Rat Genome Database

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Gene: KLF6 (Kruppel like factor 6) Homo sapiens
Analyze
Symbol: KLF6
Name: Kruppel like factor 6
RGD ID: 1349381
HGNC Page HGNC
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Localizes to cytosol; fibrillar center; and nucleoplasm. Implicated in prostate cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: B-cell-derived protein 1; BCD1; CBA1; COPEB; core promoter element binding protein; core promoter element-binding protein; CPBP; DKFZp686N0199; GBF; GC-rich binding factor; GC-rich sites-binding factor GBF; Krueppel-like factor 6; Kruppel-like factor 6; Kruppel-like zinc finger protein Zf9; PAC1; proto-oncogene BCD1; protooncogene B-cell derived 1; ST12; suppression of tumorigenicity 12 (prostate); suppressor of tumorigenicity 12 protein; transcription factor Zf9; ZF9
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl103,775,996 - 3,785,281 (-)EnsemblGRCh38hg38GRCh38
GRCh38103,775,996 - 3,785,209 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37103,818,188 - 3,827,401 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36103,811,234 - 3,817,455 (-)NCBINCBI36hg18NCBI36
Build 34103,811,240 - 3,817,455NCBI
Celera103,763,066 - 3,772,350 (-)NCBI
Cytogenetic Map10p15.2NCBI
HuRef103,754,750 - 3,764,030 (-)NCBIHuRef
CHM1_1103,818,788 - 3,828,068 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (EXP)
(S)-colchicine  (EXP)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4-dinitrobenzene  (EXP)
1-methylphenanthrene  (EXP)
1-naphthyl isothiocyanate  (EXP,ISO)
15-deoxy-Delta(12,14)-prostaglandin J2  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
2-hydroxypropanoic acid  (EXP)
2-methylcholine  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,5-diethoxycarbonyl-1,4-dihydrocollidine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (EXP)
5-aza-2'-deoxycytidine  (EXP)
5-azacytidine  (EXP)
5-fluorouracil  (EXP)
9-cis-retinoic acid  (ISO)
acetamide  (ISO)
acrolein  (EXP)
aflatoxin B1  (EXP,ISO)
alachlor  (ISO)
aldehydo-D-glucose  (ISO)
alpha-pinene  (EXP)
ammonium chloride  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP)
antimony(0)  (EXP)
arachidonic acid  (EXP)
Aroclor 1254  (ISO)
arsenite(3-)  (EXP)
atrazine  (EXP)
azathioprine  (EXP)
benzene  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (EXP)
benzoates  (EXP)
beta-naphthoflavone  (EXP)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (ISO)
bisphenol F  (ISO)
bortezomib  (EXP)
cadmium atom  (EXP)
cadmium dichloride  (ISO)
carbamazepine  (EXP)
carbonyl sulfide  (ISO)
chloropicrin  (EXP)
chloroprene  (ISO)
choline  (ISO)
cisplatin  (EXP,ISO)
clofibrate  (ISO)
cobalt dichloride  (EXP,ISO)
copper(II) chloride  (EXP)
copper(II) sulfate  (EXP)
coumestrol  (EXP)
crocidolite asbestos  (EXP)
curcumin  (EXP)
cyclosporin A  (EXP,ISO)
cylindrospermopsin  (EXP)
D-glucose  (ISO)
Diallyl sulfide  (EXP)
dibutyl phthalate  (ISO)
dicoumarol  (EXP)
dieldrin  (EXP)
dioxygen  (EXP)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (EXP)
diuron  (ISO)
dorsomorphin  (EXP)
doxorubicin  (EXP)
elemental selenium  (EXP)
Enterolactone  (EXP)
ethanol  (ISO)
ethyl methanesulfonate  (EXP)
etoposide  (EXP)
fluoranthene  (ISO)
folic acid  (ISO)
formaldehyde  (EXP)
fumonisin B1  (ISO)
gentamycin  (ISO)
geraniol  (EXP)
glucose  (ISO)
hydralazine  (EXP)
hydrogen peroxide  (EXP)
indole-3-methanol  (ISO)
ionomycin  (EXP)
isobutanol  (EXP)
ketamine  (ISO)
L-methionine  (ISO)
lead diacetate  (ISO)
leflunomide  (EXP)
lipopolysaccharide  (ISO)
lithium atom  (EXP)
lithium hydride  (EXP)
MeIQx  (EXP)
menadione  (EXP)
mercury dibromide  (EXP)
mercury dichloride  (ISO)
methamphetamine  (ISO)
methyl methanesulfonate  (EXP)
methylmercury chloride  (EXP)
methyltestosterone  (EXP)
mitomycin C  (EXP)
N-acetylsphingosine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (EXP)
N-methyl-4-phenylpyridinium  (ISO)
N-methylformamide  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (EXP,ISO)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (ISO)
nickel atom  (ISO)
nickel dichloride  (EXP,ISO)
nickel sulfate  (EXP)
O-methyleugenol  (ISO)
oxaliplatin  (ISO)
ozone  (EXP,ISO)
panobinostat  (EXP)
paracetamol  (EXP,ISO)
paraquat  (EXP)
pentanal  (EXP)
perfluorooctanoic acid  (ISO)
phenobarbital  (EXP,ISO)
phenol  (EXP)
phenylmercury acetate  (EXP)
phorbol 13-acetate 12-myristate  (EXP)
piperonyl butoxide  (ISO)
pirinixic acid  (EXP,ISO)
potassium chromate  (EXP)
progesterone  (EXP)
pyrrolidine dithiocarbamate  (EXP)
quercetin  (EXP)
rac-lactic acid  (EXP)
raloxifene  (ISO)
ranitidine  (ISO)
reactive oxygen species  (EXP)
rifampicin  (EXP)
rimonabant  (ISO)
rotenone  (ISO)
S-adenosyl-L-methioninate  (ISO)
S-adenosyl-L-methionine  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (EXP)
Salinomycin  (EXP)
SB 203580  (EXP)
SB 431542  (EXP)
selenium atom  (EXP)
silicon dioxide  (EXP,ISO)
silver atom  (EXP)
silver(0)  (EXP)
simvastatin  (EXP)
sirolimus  (ISO)
sodium arsenate  (ISO)
sodium dichromate  (ISO)
sodium fluoride  (ISO)
Soman  (ISO)
succimer  (ISO)
tacrolimus hydrate  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (ISO)
titanium dioxide  (ISO)
topotecan  (ISO)
torcetrapib  (EXP)
trichloroethene  (ISO)
trichostatin A  (EXP)
triphenyl phosphate  (ISO)
troglitazone  (EXP)
urethane  (EXP)
valproic acid  (EXP)
vancomycin  (ISO)
venlafaxine hydrochloride  (ISO)
vinclozolin  (ISO)
vincristine  (EXP)
vitamin E  (EXP)
vorinostat  (EXP)
wortmannin  (EXP)
zinc atom  (EXP)
zinc(0)  (EXP)

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

Additional References at PubMed
PMID:8889548   PMID:9000136   PMID:9083102   PMID:9503030   PMID:9685731   PMID:9689109   PMID:10802067   PMID:12433697   PMID:12477932   PMID:12508640   PMID:12590140   PMID:12651597  
PMID:12651626   PMID:12740910   PMID:12794452   PMID:15057748   PMID:15064720   PMID:15067324   PMID:15131018   PMID:15164054   PMID:15172998   PMID:15247715   PMID:15342556   PMID:15378003  
PMID:15486921   PMID:15489334   PMID:15735005   PMID:15824733   PMID:15917248   PMID:15937668   PMID:16044160   PMID:16054710   PMID:16169070   PMID:16189514   PMID:16385451   PMID:16431954  
PMID:16500425   PMID:16598737   PMID:16702959   PMID:16778100   PMID:16856969   PMID:16872311   PMID:16972326   PMID:16988269   PMID:17071613   PMID:17113081   PMID:17125911   PMID:17143513  
PMID:17207965   PMID:17223258   PMID:17347589   PMID:17347668   PMID:17514651   PMID:17621627   PMID:17636026   PMID:17663506   PMID:17893646   PMID:18053161   PMID:18174288   PMID:18190240  
PMID:18250346   PMID:18471523   PMID:18515091   PMID:18521079   PMID:18596922   PMID:18691883   PMID:18719336   PMID:18753303   PMID:18755691   PMID:18822210   PMID:19020536   PMID:19097929  
PMID:19101139   PMID:19274049   PMID:19328586   PMID:19333010   PMID:19435908   PMID:19808645   PMID:19967571   PMID:20014424   PMID:20116377   PMID:20126619   PMID:20237496   PMID:20453000  
PMID:20545576   PMID:20660366   PMID:20714872   PMID:20801538   PMID:20844588   PMID:21056892   PMID:21109018   PMID:21154818   PMID:21282102   PMID:21309496   PMID:21443094   PMID:21470678  
PMID:21538018   PMID:21799854   PMID:21832049   PMID:21849067   PMID:21873635   PMID:21928351   PMID:21940380   PMID:22095588   PMID:22169644   PMID:22277651   PMID:22486562   PMID:22535637  
PMID:22581522   PMID:22653055   PMID:22711891   PMID:22782870   PMID:22855058   PMID:22859706   PMID:23048070   PMID:23085750   PMID:23219426   PMID:23322324   PMID:23345610   PMID:23353867  
PMID:23508266   PMID:23512538   PMID:23831683   PMID:23870195   PMID:23977008   PMID:24130502   PMID:24322504   PMID:24366496   PMID:24385430   PMID:24519062   PMID:24634218   PMID:24921656  
PMID:25182666   PMID:25230316   PMID:25537765   PMID:25652467   PMID:25686501   PMID:25879517   PMID:26193637   PMID:26838049   PMID:26850053   PMID:27057625   PMID:27510817   PMID:27577710  
PMID:27629257   PMID:27734217   PMID:27760566   PMID:27779691   PMID:27780824   PMID:28166199   PMID:28473536   PMID:28638139   PMID:28638268   PMID:29066014   PMID:29084019   PMID:29101805  
PMID:29117863   PMID:29432497   PMID:29807011   PMID:29854578   PMID:29970714   PMID:30115650   PMID:30273693   PMID:30287840   PMID:30590988   PMID:30628682   PMID:30700579   PMID:30858363  
PMID:31210314   PMID:31723124   PMID:32145913   PMID:32210535   PMID:32222722   PMID:32275946   PMID:32473153   PMID:32733026   PMID:32814053  


Genomics

Comparative Map Data
KLF6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl103,775,996 - 3,785,281 (-)EnsemblGRCh38hg38GRCh38
GRCh38103,775,996 - 3,785,209 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37103,818,188 - 3,827,401 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36103,811,234 - 3,817,455 (-)NCBINCBI36hg18NCBI36
Build 34103,811,240 - 3,817,455NCBI
Celera103,763,066 - 3,772,350 (-)NCBI
Cytogenetic Map10p15.2NCBI
HuRef103,754,750 - 3,764,030 (-)NCBIHuRef
CHM1_1103,818,788 - 3,828,068 (-)NCBICHM1_1
Klf6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39135,911,488 - 5,920,392 (+)NCBIGRCm39mm39
GRCm39 Ensembl135,911,481 - 5,920,393 (+)Ensembl
GRCm38135,861,489 - 5,870,393 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl135,861,482 - 5,870,394 (+)EnsemblGRCm38mm10GRCm38
MGSCv37135,860,735 - 5,869,639 (+)NCBIGRCm37mm9NCBIm37
MGSCv36135,860,735 - 5,869,639 (+)NCBImm8
Celera135,806,926 - 5,815,830 (+)NCBICelera
Cytogenetic Map13A1NCBI
Klf6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21764,539,456 - 64,548,451 (-)NCBI
Rnor_6.0 Ensembl1767,887,939 - 67,945,037 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01767,887,939 - 67,945,052 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01769,616,967 - 69,674,031 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41775,578,498 - 75,585,072 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11775,589,332 - 75,595,905 (-)NCBI
Celera1764,125,707 - 64,134,702 (-)NCBICelera
Cytogenetic Map17q12.1NCBI
Klf6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554291,838,537 - 1,846,915 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554291,838,537 - 1,846,915 (+)NCBIChiLan1.0ChiLan1.0
KLF6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1103,789,893 - 3,798,057 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl103,789,893 - 3,796,379 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0103,781,797 - 3,790,539 (-)NCBIMhudiblu_PPA_v0panPan3
KLF6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1231,654,142 - 31,664,009 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl231,654,175 - 31,662,351 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha228,683,538 - 28,693,072 (+)NCBI
ROS_Cfam_1.0232,036,878 - 32,046,413 (+)NCBI
UMICH_Zoey_3.1229,123,207 - 29,131,390 (+)NCBI
UNSW_CanFamBas_1.0229,962,128 - 29,971,626 (+)NCBI
UU_Cfam_GSD_1.0230,688,899 - 30,698,432 (+)NCBI
Klf6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934434,305,208 - 34,311,507 (+)NCBI
SpeTri2.0NW_00493648410,470,384 - 10,476,682 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
KLF6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1066,488,391 - 66,497,844 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11066,488,445 - 66,497,830 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21072,992,298 - 73,001,801 (+)NCBISscrofa10.2Sscrofa10.2susScr3
KLF6
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.193,872,376 - 3,881,238 (-)NCBI
ChlSab1.1 Ensembl93,875,356 - 3,881,229 (-)Ensembl
Klf6
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247961,531,934 - 1,539,728 (+)NCBI

Position Markers
RH48829  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37103,821,077 - 3,821,205UniSTSGRCh37
Build 36103,811,077 - 3,811,205RGDNCBI36
Celera103,765,955 - 3,766,083RGD
Cytogenetic Map10p15UniSTS
HuRef103,757,639 - 3,757,767UniSTS
GeneMap99-GB4 RH Map1039.82UniSTS
NCBI RH Map10103.9UniSTS
G62122  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37103,821,519 - 3,821,638UniSTSGRCh37
Build 36103,811,519 - 3,811,638RGDNCBI36
Celera103,766,397 - 3,766,516RGD
Cytogenetic Map10p15UniSTS
HuRef103,758,081 - 3,758,200UniSTS
WI-12084  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37103,821,275 - 3,821,415UniSTSGRCh37
Build 36103,811,275 - 3,811,415RGDNCBI36
Celera103,766,153 - 3,766,293RGD
Cytogenetic Map10p15UniSTS
HuRef103,757,837 - 3,757,977UniSTS
GeneMap99-GB4 RH Map1039.82UniSTS
Whitehead-RH Map1039.0UniSTS
NCBI RH Map10103.9UniSTS
D10S1368E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37103,819,344 - 3,819,445UniSTSGRCh37
Build 36103,809,344 - 3,809,445RGDNCBI36
Celera103,764,222 - 3,764,323RGD
Cytogenetic Map10p15UniSTS
HuRef103,755,906 - 3,756,007UniSTS
GeneMap99-GB4 RH Map1038.19UniSTS
NCBI RH Map10103.9UniSTS
D10S2364  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37103,819,191 - 3,819,288UniSTSGRCh37
Build 36103,809,191 - 3,809,288RGDNCBI36
Celera103,764,068 - 3,764,165RGD
Cytogenetic Map10p15UniSTS
HuRef103,755,752 - 3,755,849UniSTS
Stanford-G3 RH Map10117.0UniSTS
NCBI RH Map1081.8UniSTS
GeneMap99-G3 RH Map10117.0UniSTS
STS-AA018922  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37103,823,873 - 3,824,114UniSTSGRCh37
Build 36103,813,873 - 3,814,114RGDNCBI36
Celera103,768,751 - 3,768,992RGD
Cytogenetic Map10p15UniSTS
HuRef103,760,430 - 3,760,671UniSTS
GeneMap99-GB4 RH Map1039.82UniSTS
NCBI RH Map10103.9UniSTS
COPEB_2513  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37103,821,100 - 3,821,710UniSTSGRCh37
Build 36103,811,100 - 3,811,710RGDNCBI36
Celera103,765,978 - 3,766,588RGD
HuRef103,757,662 - 3,758,272UniSTS

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
MIR181A2hsa-miR-181a-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI22581522
MIR181A2hsa-miR-181a-5pOncomiRDBexternal_infoNANA22581522
MIR181A1hsa-miR-181a-5pMirtarbaseexternal_infoLuciferase reporter assay//qRT-PCR//Western blotFunctional MTI22581522
MIR181A1hsa-miR-181a-5pOncomiRDBexternal_infoNANA22581522

Predicted Target Of
Summary Value
Count of predictions:4748
Count of miRNA genes:1231
Interacting mature miRNAs:1563
Transcripts:ENST00000173785, ENST00000380946, ENST00000461124, ENST00000469435, ENST00000492125, ENST00000497571, ENST00000542957
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component
High 2 2
Medium 2432 2888 1567 580 1919 422 4345 2103 2188 412 1428 1594 171 1204 2778 3
Low 1 96 156 42 28 42 11 92 1521 6 18 16 1 10 1
Below cutoff 2 2 1 1 1 1 7 1 9 3 3 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_012277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001160124 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001160125 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001300 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_027653 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB017493 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF001461 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF284036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI355637 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK293259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK316596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL450322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL513303 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC000311 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC004301 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC015987 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM544849 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM695496 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP357332 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ017028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BT006778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX537374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD742988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR975091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR994352 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ619623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HI573934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HI573936 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U44975 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U51869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000173785
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl103,779,047 - 3,782,051 (-)Ensembl
RefSeq Acc Id: ENST00000380946
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl103,781,808 - 3,785,183 (-)Ensembl
RefSeq Acc Id: ENST00000461124
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl103,775,996 - 3,780,217 (-)Ensembl
RefSeq Acc Id: ENST00000469435   ⟹   ENSP00000419079
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl103,780,327 - 3,785,193 (-)Ensembl
RefSeq Acc Id: ENST00000492125
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl103,779,550 - 3,780,496 (-)Ensembl
RefSeq Acc Id: ENST00000497571   ⟹   ENSP00000419923
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl103,775,996 - 3,785,209 (-)Ensembl
RefSeq Acc Id: ENST00000542957   ⟹   ENSP00000445301
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl103,775,997 - 3,785,281 (-)Ensembl
RefSeq Acc Id: NM_001160124   ⟹   NP_001153596
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38103,775,996 - 3,785,209 (-)NCBI
GRCh37103,818,188 - 3,827,473 (-)ENTREZGENE
HuRef103,754,750 - 3,764,030 (-)ENTREZGENE
CHM1_1103,818,788 - 3,828,068 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001160125   ⟹   NP_001153597
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38103,775,996 - 3,785,209 (-)NCBI
GRCh37103,818,188 - 3,827,473 (-)ENTREZGENE
HuRef103,754,750 - 3,764,030 (-)ENTREZGENE
CHM1_1103,818,788 - 3,828,068 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001300   ⟹   NP_001291
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38103,775,996 - 3,785,209 (-)NCBI
GRCh37103,818,188 - 3,827,473 (-)ENTREZGENE
Build 36103,811,234 - 3,817,455 (-)NCBI Archive
HuRef103,754,750 - 3,764,030 (-)ENTREZGENE
CHM1_1103,818,788 - 3,828,068 (-)NCBI
Sequence:
RefSeq Acc Id: NR_027653
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38103,775,996 - 3,785,209 (-)NCBI
GRCh37103,818,188 - 3,827,473 (-)ENTREZGENE
HuRef103,754,750 - 3,764,030 (-)ENTREZGENE
CHM1_1103,818,788 - 3,828,068 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001153596   ⟸   NM_001160124
- Peptide Label: isoform B
- UniProtKB: Q99612 (UniProtKB/Swiss-Prot),   D3GC14 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001153597   ⟸   NM_001160125
- Peptide Label: isoform C
- UniProtKB: Q99612 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001291   ⟸   NM_001300
- Peptide Label: isoform A
- UniProtKB: Q99612 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000445301   ⟸   ENST00000542957
RefSeq Acc Id: ENSP00000419079   ⟸   ENST00000469435
RefSeq Acc Id: ENSP00000419923   ⟸   ENST00000497571
Protein Domains
C2H2-type

Promoters
RGD ID:7216875
Promoter ID:EPDNEW_H14184
Type:initiation region
Name:KLF6_1
Description:Kruppel like factor 6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38103,785,209 - 3,785,269EPDNEW
RGD ID:6815824
Promoter ID:HG_SPT:6431
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562
Transcripts:AI355637,   BE617725,   CD742988
Position:
Human AssemblyChrPosition (strand)Source
Build 36103,807,661 - 3,808,412 (+)MPROMDB
RGD ID:6787837
Promoter ID:HG_KWN:8388
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   K562,   Lymphoblastoid
Transcripts:OTTHUMT00000046499,   OTTHUMT00000046500
Position:
Human AssemblyChrPosition (strand)Source
Build 36103,812,426 - 3,813,627 (-)MPROMDB
RGD ID:6787834
Promoter ID:HG_KWN:8389
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   K562,   Lymphoblastoid
Transcripts:OTTHUMT00000046498
Position:
Human AssemblyChrPosition (strand)Source
Build 36103,813,786 - 3,815,217 (-)MPROMDB
RGD ID:6787833
Promoter ID:HG_KWN:8390
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000322510,   NM_001160124,   NM_001160125,   NR_027653,   OTTHUMT00000046495,   OTTHUMT00000046497,   UC001IHB.1
Position:
Human AssemblyChrPosition (strand)Source
Build 36103,817,061 - 3,818,277 (-)MPROMDB
RGD ID:6851684
Promoter ID:EP73644
Type:initiation region
Name:HS_COPEB
Description:Core promoter element binding protein.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:NEDO full length human cDNA sequencing project.; Oligo-capping
Position:
Human AssemblyChrPosition (strand)Source
Build 36103,817,401 - 3,817,461EPD

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_001300.6(KLF6):c.346T>C (p.Ser116Pro) single nucleotide variant Prostate cancer, somatic [RCV000008005] Chr10:3781971 [GRCh38]
Chr10:3824163 [GRCh37]
Chr10:10p15.2
pathogenic|other
NM_001300.6(KLF6):c.410C>A (p.Ser137Ter) single nucleotide variant Prostate cancer, somatic [RCV000008006] Chr10:3781907 [GRCh38]
Chr10:3824099 [GRCh37]
Chr10:10p15.2
pathogenic|other
NM_001300.6(KLF6):c.368C>A (p.Ala123Asp) single nucleotide variant Prostate cancer, somatic [RCV000008007] Chr10:3781949 [GRCh38]
Chr10:3824141 [GRCh37]
Chr10:10p15.2
pathogenic|other
NM_001300.6(KLF6):c.190T>C (p.Trp64Arg) single nucleotide variant Prostate cancer, somatic [RCV000008008] Chr10:3782127 [GRCh38]
Chr10:3824319 [GRCh37]
Chr10:10p15.2
pathogenic|other
NM_001300.6(KLF6):c.506T>C (p.Leu169Pro) single nucleotide variant Prostate cancer, somatic [RCV000008009] Chr10:3781811 [GRCh38]
Chr10:3824003 [GRCh37]
Chr10:10p15.2
pathogenic|other
NM_001300.6(KLF6):c.465C>A (p.Ser155Arg) single nucleotide variant Neoplasm of stomach [RCV000008010] Chr10:3781852 [GRCh38]
Chr10:3824044 [GRCh37]
Chr10:10p15.2
pathogenic|other
GRCh38/hg38 10p15.3-14(chr10:90421-6769994)x3 copy number gain See cases [RCV000051132] Chr10:90421..6769994 [GRCh38]
Chr10:224406..6811956 [GRCh37]
Chr10:126361..6851962 [NCBI36]
Chr10:10p15.3-14
pathogenic
GRCh38/hg38 10p15.3-14(chr10:90421-8442783)x3 copy number gain See cases [RCV000051107] Chr10:90421..8442783 [GRCh38]
Chr10:224406..8484746 [GRCh37]
Chr10:126361..8524752 [NCBI36]
Chr10:10p15.3-14
pathogenic
GRCh38/hg38 10p15.3-15.1(chr10:69260-6209368)x1 copy number loss See cases [RCV000052493] Chr10:69260..6209368 [GRCh38]
Chr10:224406..6251331 [GRCh37]
Chr10:105200..6291337 [NCBI36]
Chr10:10p15.3-15.1
pathogenic
GRCh38/hg38 10p15.3-13(chr10:90421-15569528)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052496]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052496]|See cases [RCV000052496] Chr10:90421..15569528 [GRCh38]
Chr10:224406..15611527 [GRCh37]
Chr10:126361..15651533 [NCBI36]
Chr10:10p15.3-13
pathogenic
GRCh38/hg38 10p15.3-12.31(chr10:69261-19184047)x3 copy number gain See cases [RCV000053507] Chr10:69261..19184047 [GRCh38]
Chr10:224406..19472976 [GRCh37]
Chr10:105201..19512982 [NCBI36]
Chr10:10p15.3-12.31
pathogenic
GRCh38/hg38 10p15.3-12.2(chr10:90221-22567425)x3 copy number gain See cases [RCV000053508] Chr10:90221..22567425 [GRCh38]
Chr10:224406..22856354 [GRCh37]
Chr10:126161..22896360 [NCBI36]
Chr10:10p15.3-12.2
pathogenic
GRCh38/hg38 10p15.3-14(chr10:90421-7085100)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053511]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053511]|See cases [RCV000053511] Chr10:90421..7085100 [GRCh38]
Chr10:224406..7127062 [GRCh37]
Chr10:126361..7167068 [NCBI36]
Chr10:10p15.3-14
pathogenic
GRCh38/hg38 10p15.3-12.1(chr10:90421-29058318)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053512]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053512]|See cases [RCV000053512] Chr10:90421..29058318 [GRCh38]
Chr10:224406..29347247 [GRCh37]
Chr10:126361..29387253 [NCBI36]
Chr10:10p15.3-12.1
pathogenic
NM_001300.6(KLF6):c.*46A>T single nucleotide variant Hypotension [RCV000119252] Chr10:3779493 [GRCh38]
Chr10:3821685 [GRCh37]
Chr10:10p15.2
not provided
NM_001300.6(KLF6):c.*62G>A single nucleotide variant Hypotension [RCV000119253] Chr10:3779477 [GRCh38]
Chr10:3821669 [GRCh37]
Chr10:10p15.2
not provided
NM_001300.6(KLF6):c.496C>T (p.Pro166Ser) single nucleotide variant Hypotension [RCV000119254] Chr10:3781821 [GRCh38]
Chr10:3824013 [GRCh37]
Chr10:10p15.2
not provided
NM_001300.6(KLF6):c.603G>A (p.Arg201=) single nucleotide variant Hypotension [RCV000119255]|not provided [RCV000881384] Chr10:3781714 [GRCh38]
Chr10:3823906 [GRCh37]
Chr10:10p15.2
benign|not provided
NM_001300.6(KLF6):c.800+21C>T single nucleotide variant Hypotension [RCV000119256] Chr10:3780085 [GRCh38]
Chr10:3822277 [GRCh37]
Chr10:10p15.2
not provided
NM_001300.6(KLF6):c.800+34G>A single nucleotide variant Hypotension [RCV000119257] Chr10:3780072 [GRCh38]
Chr10:3822264 [GRCh37]
Chr10:10p15.2
not provided
NM_001300.6(KLF6):c.276C>A (p.Ser92Arg) single nucleotide variant not specified [RCV000121325] Chr10:3782041 [GRCh38]
Chr10:3824233 [GRCh37]
Chr10:10p15.2
not provided
NM_001300.6(KLF6):c.428C>T (p.Ser143Phe) single nucleotide variant not specified [RCV000121326] Chr10:3781889 [GRCh38]
Chr10:3824081 [GRCh37]
Chr10:10p15.2
not provided
NM_001300.6(KLF6):c.493G>A (p.Val165Met) single nucleotide variant not provided [RCV000890849]|not specified [RCV000121327] Chr10:3781824 [GRCh38]
Chr10:3824016 [GRCh37]
Chr10:10p15.2
benign|not provided
NM_001300.6(KLF6):c.676+28C>T single nucleotide variant not specified [RCV000119853] Chr10:3781613 [GRCh38]
Chr10:3823805 [GRCh37]
Chr10:10p15.2
not provided
NM_001300.6(KLF6):c.676+61C>T single nucleotide variant not specified [RCV000119852] Chr10:3781580 [GRCh38]
Chr10:3823772 [GRCh37]
Chr10:10p15.2
not provided
NM_001300.6(KLF6):c.676+106G>A single nucleotide variant not specified [RCV000119851] Chr10:3781535 [GRCh38]
Chr10:3823727 [GRCh37]
Chr10:10p15.2
not provided
GRCh37/hg19 10p15.3-15.1(chr10:138878-5160945)x3 copy number gain See cases [RCV000184089] Chr10:138878..5160945 [GRCh37]
Chr10:10p15.3-15.1
pathogenic
GRCh38/hg38 10p15.3-13(chr10:73856-12815915)x3 copy number gain See cases [RCV000135340] Chr10:73856..12815915 [GRCh38]
Chr10:119796..12857914 [GRCh37]
Chr10:109796..12897920 [NCBI36]
Chr10:10p15.3-13
pathogenic
GRCh38/hg38 10p15.3-14(chr10:90421-11713049)x3 copy number gain See cases [RCV000135533] Chr10:90421..11713049 [GRCh38]
Chr10:224406..11755048 [GRCh37]
Chr10:126361..11795054 [NCBI36]
Chr10:10p15.3-14
pathogenic|uncertain significance
GRCh38/hg38 10p15.3-13(chr10:70478-15373336)x3 copy number gain See cases [RCV000137384] Chr10:70478..15373336 [GRCh38]
Chr10:224406..15415335 [GRCh37]
Chr10:106418..15455341 [NCBI36]
Chr10:10p15.3-13
uncertain significance
GRCh38/hg38 10p15.3-12.1(chr10:90205-26339978)x3 copy number gain See cases [RCV000138428] Chr10:90205..26339978 [GRCh38]
Chr10:224406..26628907 [GRCh37]
Chr10:126145..26668913 [NCBI36]
Chr10:10p15.3-12.1
pathogenic
GRCh38/hg38 10p15.3-13(chr10:70478-13736564)x1 copy number loss See cases [RCV000138960] Chr10:70478..13736564 [GRCh38]
Chr10:224406..13778564 [GRCh37]
Chr10:106418..13818570 [NCBI36]
Chr10:10p15.3-13
pathogenic
GRCh38/hg38 10p15.3-13(chr10:54086-13205916)x3 copy number gain See cases [RCV000142292] Chr10:54086..13205916 [GRCh38]
Chr10:100026..13247916 [GRCh37]
Chr10:90026..13287922 [NCBI36]
Chr10:10p15.3-13
pathogenic
GRCh38/hg38 10p15.3-14(chr10:1601172-9203729)x3 copy number gain See cases [RCV000142241] Chr10:1601172..9203729 [GRCh38]
Chr10:1643367..9245692 [GRCh37]
Chr10:1633367..9285698 [NCBI36]
Chr10:10p15.3-14
likely pathogenic
GRCh38/hg38 10p15.3-12.31(chr10:54086-19336980)x1 copy number loss See cases [RCV000143703] Chr10:54086..19336980 [GRCh38]
Chr10:100026..19625909 [GRCh37]
Chr10:90026..19665915 [NCBI36]
Chr10:10p15.3-12.31
pathogenic|likely pathogenic
GRCh37/hg19 10p15.3-14(chr10:2593113-8484746)x1 copy number loss See cases [RCV000239795] Chr10:2593113..8484746 [GRCh37]
Chr10:10p15.3-14
pathogenic
GRCh37/hg19 10p15.3-14(chr10:136361-8850609)x1 copy number loss See cases [RCV000446357] Chr10:136361..8850609 [GRCh37]
Chr10:10p15.3-14
pathogenic
GRCh37/hg19 10p15.3-11.23(chr10:100026-30278548)x3 copy number gain See cases [RCV000447131] Chr10:100026..30278548 [GRCh37]
Chr10:10p15.3-11.23
pathogenic
GRCh37/hg19 10p15.3-14(chr10:2116123-8856296)x3 copy number gain See cases [RCV000445989] Chr10:2116123..8856296 [GRCh37]
Chr10:10p15.3-14
uncertain significance
GRCh37/hg19 10p15.3-q26.3(chr10:93297-135378918)x3 copy number gain See cases [RCV000448750] Chr10:93297..135378918 [GRCh37]
Chr10:10p15.3-q26.3
pathogenic
GRCh37/hg19 10p15.3-15.1(chr10:100026-4853435)x3 copy number gain See cases [RCV000510194] Chr10:100026..4853435 [GRCh37]
Chr10:10p15.3-15.1
uncertain significance
GRCh37/hg19 10p15.3-q26.3(chr10:100027-135427143) copy number gain See cases [RCV000511389] Chr10:100027..135427143 [GRCh37]
Chr10:10p15.3-q26.3
pathogenic|uncertain significance
GRCh37/hg19 10p15.3-q26.3(chr10:100027-135427143)x3 copy number gain See cases [RCV000510861] Chr10:100027..135427143 [GRCh37]
Chr10:10p15.3-q26.3
pathogenic
GRCh37/hg19 10p15.3-q11.23(chr10:100026-50961640)x3 copy number gain See cases [RCV000510893] Chr10:100026..50961640 [GRCh37]
Chr10:10p15.3-q11.23
pathogenic
GRCh37/hg19 10p15.3-15.1(chr10:100026-4761588)x1 copy number loss See cases [RCV000511142] Chr10:100026..4761588 [GRCh37]
Chr10:10p15.3-15.1
pathogenic
GRCh37/hg19 10p15.3-13(chr10:100026-12842179)x1 copy number loss See cases [RCV000512541] Chr10:100026..12842179 [GRCh37]
Chr10:10p15.3-13
pathogenic
Single allele duplication Schizophrenia [RCV000754118] Chr10:3076972..6208037 [GRCh38]
Chr10:10p15.2-15.1
likely pathogenic
GRCh37/hg19 10p15.3-13(chr10:69083-12887271)x3 copy number gain not provided [RCV000749463] Chr10:69083..12887271 [GRCh37]
Chr10:10p15.3-13
pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:73232-135524321)x3 copy number gain not provided [RCV000749464] Chr10:73232..135524321 [GRCh37]
Chr10:10p15.3-q26.3
pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:98087-135477883)x3 copy number gain not provided [RCV000749465] Chr10:98087..135477883 [GRCh37]
Chr10:10p15.3-q26.3
pathogenic
GRCh37/hg19 10p15.3-13(chr10:100026-15273144)x3 copy number gain not provided [RCV000848062] Chr10:100026..15273144 [GRCh37]
Chr10:10p15.3-13
pathogenic
GRCh37/hg19 10p15.3-15.1(chr10:100026-4433206)x3 copy number gain not provided [RCV001006286] Chr10:100026..4433206 [GRCh37]
Chr10:10p15.3-15.1
pathogenic
GRCh37/hg19 10p15.3-13(chr10:100026-15273144)x3 copy number gain not provided [RCV000848090] Chr10:100026..15273144 [GRCh37]
Chr10:10p15.3-13
pathogenic
NM_001300.6(KLF6):c.594G>A (p.Arg198=) single nucleotide variant not provided [RCV000953615] Chr10:3781723 [GRCh38]
Chr10:3823915 [GRCh37]
Chr10:10p15.2
benign
NM_001300.6(KLF6):c.231C>T (p.Ser77=) single nucleotide variant not provided [RCV000890850] Chr10:3782086 [GRCh38]
Chr10:3824278 [GRCh37]
Chr10:10p15.2
benign

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:2235 AgrOrtholog
COSMIC KLF6 COSMIC
Ensembl Genes ENSG00000067082 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSP00000419079 UniProtKB/Swiss-Prot
  ENSP00000419923 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000445301 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000469435 UniProtKB/Swiss-Prot
  ENST00000497571 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000542957 ENTREZGENE, UniProtKB/Swiss-Prot
GTEx ENSG00000067082 GTEx
HGNC ID HGNC:2235 ENTREZGENE
Human Proteome Map KLF6 Human Proteome Map
InterPro Znf_C2H2_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_C2H2_type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:1316 UniProtKB/Swiss-Prot
NCBI Gene 1316 ENTREZGENE
OMIM 176807 OMIM
  601188 OMIM
  602053 OMIM
  613659 OMIM
Pfam zf-C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA26751 PharmGKB
PROSITE ZINC_FINGER_C2H2_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_FINGER_C2H2_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART ZnF_C2H2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF57667 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt D3GC14 ENTREZGENE, UniProtKB/TrEMBL
  KLF6_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary B2RE86 UniProtKB/Swiss-Prot
  B4DDN0 UniProtKB/Swiss-Prot
  D3DRR1 UniProtKB/Swiss-Prot
  F5H3M5 UniProtKB/Swiss-Prot
  Q5VUT7 UniProtKB/Swiss-Prot
  Q5VUT8 UniProtKB/Swiss-Prot
  Q9BT79 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-07 KLF6  Kruppel like factor 6  KLF6  Kruppel-like factor 6  Symbol and/or name change 5135510 APPROVED