S100A11 (S100 calcium binding protein A11) - Rat Genome Database

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Gene: S100A11 (S100 calcium binding protein A11) Homo sapiens
Analyze
Symbol: S100A11
Name: S100 calcium binding protein A11
RGD ID: 1323591
HGNC Page HGNC
Description: Exhibits S100 protein binding activity; calcium-dependent protein binding activity; and protein homodimerization activity. Involved in positive regulation of smooth muscle cell migration. Localizes to cytoplasm; nucleus; and ruffle.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: calgizzarin; epididymis secretory protein Li 43; HEL-S-43; metastatic lymph node gene 70 protein; MLN 70; MLN70; protein S100-A11; protein S100-C; s100 calcium binding protein a11 (calgizzarin); S100 calcium-binding protein A11 (calgizzarin); S100C
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: LOC100288712   S100A11P1   S100A11P2   S100A11P3   S100A11P4  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1152,032,506 - 152,047,907 (-)EnsemblGRCh38hg38GRCh38
GRCh381152,032,506 - 152,037,004 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371152,004,982 - 152,009,480 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361150,271,606 - 150,276,135 (-)NCBINCBI36hg18NCBI36
Build 341148,818,054 - 148,822,584NCBI
Celera1125,119,617 - 125,124,146 (-)NCBI
Cytogenetic Map1q21.3NCBI
HuRef1123,382,878 - 123,387,406 (-)NCBIHuRef
CHM1_11153,400,219 - 153,404,748 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (EXP)
(+)-schisandrin B  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-acetamidofluorene  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (EXP)
5-fluorouracil  (EXP,ISO)
6-propyl-2-thiouracil  (ISO)
AACOCF3  (EXP)
acetamide  (ISO)
acetylsalicylic acid  (EXP)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (EXP,ISO)
amphetamine  (ISO)
ampicillin  (ISO)
antirheumatic drug  (EXP)
arsane  (EXP)
arsenic atom  (EXP)
arsenous acid  (EXP)
ATP  (EXP)
azathioprine  (EXP)
benzo[a]pyrene  (EXP,ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bleomycin A2  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
carbamazepine  (EXP)
carbon nanotube  (EXP,ISO)
carvedilol  (ISO)
chloropicrin  (EXP)
choline  (ISO)
cisplatin  (EXP)
clopidogrel  (ISO)
cobalt dichloride  (EXP,ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (EXP)
crocidolite asbestos  (EXP,ISO)
cyclosporin A  (EXP)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diallyl trisulfide  (EXP)
diarsenic trioxide  (EXP)
dopamine  (ISO)
dorsomorphin  (EXP)
doxorubicin  (EXP)
elemental selenium  (EXP)
enzyme inhibitor  (EXP)
fenoldopam  (ISO)
folic acid  (ISO)
folpet  (ISO)
fructose  (ISO)
fumonisin B1  (ISO)
furan  (ISO)
gentamycin  (ISO)
glafenine  (ISO)
graphite  (EXP)
indole-3-methanol  (ISO)
isoprenaline  (ISO)
ketamine  (ISO)
L-methionine  (ISO)
lead(II) chloride  (EXP)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
mercury dibromide  (EXP)
methamphetamine  (ISO)
methotrexate  (EXP)
methylmercury chloride  (EXP)
metronidazole  (ISO)
microcystin-LR  (ISO)
Miglitol  (EXP)
mitomycin C  (EXP)
N-acetyl-L-cysteine  (EXP)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
neomycin  (ISO)
nickel atom  (EXP)
O-methyleugenol  (EXP)
oxaliplatin  (EXP)
panobinostat  (EXP)
paracetamol  (EXP,ISO)
PCB138  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (EXP)
pirinixic acid  (ISO)
potassium chromate  (EXP)
quercetin  (EXP)
rotenone  (ISO)
SB 431542  (EXP)
SCH 23390  (ISO)
selenium atom  (EXP)
silicon dioxide  (ISO)
sodium fluoride  (ISO)
tetrachloromethane  (ISO)
thioacetamide  (ISO)
titanium dioxide  (ISO)
trichloroethene  (ISO)
trichostatin A  (EXP)
Triptolide  (ISO)
tris(2-butoxyethyl) phosphate  (EXP)
trovafloxacin  (ISO)
tungsten  (ISO)
valproic acid  (EXP,ISO)
vancomycin  (ISO)
vinclozolin  (ISO)
vitamin E  (EXP)
vorinostat  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

Additional References at PubMed
PMID:1286667   PMID:7490069   PMID:7759097   PMID:7889529   PMID:8557678   PMID:8985590   PMID:9287141   PMID:10486266   PMID:10673436   PMID:10851017   PMID:10913138   PMID:11258932  
PMID:11873942   PMID:12477932   PMID:12645011   PMID:12704215   PMID:14623863   PMID:14962086   PMID:15051732   PMID:15138568   PMID:15241500   PMID:15302935   PMID:15322223   PMID:15489334  
PMID:15701847   PMID:16130169   PMID:16502470   PMID:16710414   PMID:16964243   PMID:17000675   PMID:17476473   PMID:17537172   PMID:17624315   PMID:17932043   PMID:17978094   PMID:18029348  
PMID:18340452   PMID:18385759   PMID:18463164   PMID:18523305   PMID:18589612   PMID:18618420   PMID:18694925   PMID:19048101   PMID:19167051   PMID:19199708   PMID:19577285   PMID:20347987  
PMID:20372844   PMID:20379614   PMID:21139050   PMID:21674799   PMID:21861103   PMID:21873635   PMID:22304920   PMID:22319637   PMID:22430872   PMID:22658674   PMID:22869607   PMID:22903637  
PMID:22939629   PMID:23376485   PMID:23402259   PMID:23533145   PMID:23580065   PMID:23745637   PMID:23928665   PMID:24376686   PMID:24631019   PMID:24806074   PMID:25468996   PMID:25963833  
PMID:26472670   PMID:26544866   PMID:26574635   PMID:27068509   PMID:27181092   PMID:27342126   PMID:27576135   PMID:27590262   PMID:27609421   PMID:27705803   PMID:28277927   PMID:28446208  
PMID:28513300   PMID:28739510   PMID:28765046   PMID:29128334   PMID:29509190   PMID:29569474   PMID:29922945   PMID:30182496   PMID:30455460   PMID:30575818   PMID:30684913   PMID:30850029  
PMID:30963564   PMID:31046874   PMID:31430050   PMID:31442606   PMID:31594818   PMID:31837246   PMID:31980649   PMID:31985874   PMID:32296183   PMID:32416067   PMID:33001583   PMID:33571540  


Genomics

Comparative Map Data
S100A11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1152,032,506 - 152,047,907 (-)EnsemblGRCh38hg38GRCh38
GRCh381152,032,506 - 152,037,004 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371152,004,982 - 152,009,480 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361150,271,606 - 150,276,135 (-)NCBINCBI36hg18NCBI36
Build 341148,818,054 - 148,822,584NCBI
Celera1125,119,617 - 125,124,146 (-)NCBI
Cytogenetic Map1q21.3NCBI
HuRef1123,382,878 - 123,387,406 (-)NCBIHuRef
CHM1_11153,400,219 - 153,404,748 (-)NCBICHM1_1
S100a11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39393,427,803 - 93,433,595 (+)NCBIGRCm39mm39
GRCm39 Ensembl393,427,795 - 93,433,594 (+)Ensembl
GRCm38393,520,496 - 93,526,288 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl393,520,488 - 93,526,287 (+)EnsemblGRCm38mm10GRCm38
MGSCv37393,324,418 - 93,330,210 (+)NCBIGRCm37mm9NCBIm37
MGSCv36394,218,196 - 94,224,175 (+)NCBImm8
MGSCv36393,605,921 - 93,611,692 (+)NCBImm8
Celera393,567,964 - 93,573,773 (-)NCBICelera
Cytogenetic Map3F2.1NCBI
S100a11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22179,191,504 - 179,197,098 (+)NCBI
Rnor_6.0 Ensembl2193,866,951 - 193,868,502 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.02193,863,185 - 193,868,646 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.02210,998,955 - 211,004,415 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42186,620,360 - 186,621,911 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12186,570,465 - 186,572,017 (+)NCBI
Celera2171,089,693 - 171,091,244 (-)NCBICelera
Cytogenetic Map2q34NCBI
S100a11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955589408,319 - 413,971 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955589405,544 - 409,936 (+)NCBIChiLan1.0ChiLan1.0
S100A11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11131,034,588 - 131,039,130 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1131,034,588 - 131,035,882 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01127,391,695 - 127,396,231 (-)NCBIMhudiblu_PPA_v0panPan3
S100A11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11761,020,136 - 61,050,513 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1760,463,767 - 60,494,558 (-)NCBI
ROS_Cfam_1.01762,039,324 - 62,045,008 (-)NCBI
UMICH_Zoey_3.11760,865,786 - 60,896,408 (-)NCBI
UNSW_CanFamBas_1.01760,951,962 - 60,982,599 (-)NCBI
UU_Cfam_GSD_1.01761,681,384 - 61,712,178 (-)NCBI
S100A11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl497,233,499 - 97,243,423 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1497,233,833 - 97,239,081 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24106,194,355 - 106,199,599 (+)NCBISscrofa10.2Sscrofa10.2susScr3
S100A11
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12011,613,171 - 11,617,711 (+)NCBI
S100a11
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477219,563,871 - 19,568,413 (+)NCBI

Position Markers
RH17442  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371152,005,218 - 152,006,260UniSTSGRCh37
Celera1125,119,853 - 125,120,895UniSTS
Cytogenetic Map1q21UniSTS
HuRef1123,383,114 - 123,384,155UniSTS
GeneMap99-GB4 RH Map7161.63UniSTS
RH91450  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371152,005,176 - 152,006,181UniSTSGRCh37
Celera1125,119,811 - 125,120,816UniSTS
Cytogenetic Map1q21UniSTS
HuRef1123,383,072 - 123,384,076UniSTS
GeneMap99-GB4 RH Map12288.5UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:351
Count of miRNA genes:313
Interacting mature miRNAs:334
Transcripts:ENST00000271638, ENST00000478109
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High 185 1128 69 106 736 31 676 35 82 169 405 565 86 178 285 3
Medium 2246 1854 1651 515 1160 432 3678 2153 3357 249 1039 1010 85 1026 2502 1
Low 2 2 1 41 1 1 3 265 5 22 1 1
Below cutoff 1 12 2 8 1 2 11

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000271638   ⟹   ENSP00000271638
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1152,032,506 - 152,037,004 (-)Ensembl
RefSeq Acc Id: ENST00000478109
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1152,032,506 - 152,047,907 (-)Ensembl
RefSeq Acc Id: NM_005620   ⟹   NP_005611
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381152,032,506 - 152,037,004 (-)NCBI
GRCh371152,004,982 - 152,009,511 (-)ENTREZGENE
Build 361150,271,606 - 150,276,135 (-)NCBI Archive
HuRef1123,382,878 - 123,387,406 (-)ENTREZGENE
CHM1_11153,400,219 - 153,404,748 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_005611   ⟸   NM_005620
- UniProtKB: P31949 (UniProtKB/Swiss-Prot),   V9HWH9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000271638   ⟸   ENST00000271638
Protein Domains
EF-hand

Promoters
RGD ID:6814454
Promoter ID:HG_XEF:485
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell_12Hour
Transcripts:NM_001004045,   NM_001004095,   NM_001082187,   NM_001098856,   NM_016740,   NM_205166
Position:
Human AssemblyChrPosition (strand)Source
Build 361150,273,566 - 150,274,066 (-)MPROMDB
RGD ID:6786763
Promoter ID:HG_KWN:5080
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_005620
Position:
Human AssemblyChrPosition (strand)Source
Build 361150,275,801 - 150,276,301 (-)MPROMDB
RGD ID:6857114
Promoter ID:EPDNEW_H1722
Type:initiation region
Name:S100A11_1
Description:S100 calcium binding protein A11
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H1723  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381152,036,972 - 152,037,032EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 1q21.3(chr1:151858531-152298574)x1 copy number loss See cases [RCV000143761] Chr1:151858531..152298574 [GRCh38]
Chr1:151831007..152271050 [GRCh37]
Chr1:150097631..150537674 [NCBI36]
Chr1:1q21.3
uncertain significance
GRCh38/hg38 1q21.2-25.2(chr1:149854269-180267197)x3 copy number gain See cases [RCV000143515] Chr1:149854269..180267197 [GRCh38]
Chr1:149825831..180236332 [GRCh37]
Chr1:148092455..178502955 [NCBI36]
Chr1:1q21.2-25.2
pathogenic
GRCh37/hg19 1q21.1-21.3(chr1:144927578-153223600)x3 copy number gain Chromosome 1q21.1 duplication syndrome [RCV000223957] Chr1:144927578..153223600 [GRCh37]
Chr1:1q21.1-21.3
pathogenic
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684)x3 copy number gain See cases [RCV000510383] Chr1:849467..249224684 [GRCh37]
Chr1:1p36.33-q44
pathogenic
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684) copy number gain See cases [RCV000510926] Chr1:849467..249224684 [GRCh37]
Chr1:1p36.33-q44
pathogenic
GRCh37/hg19 1q21.3(chr1:150853044-154647786)x3 copy number gain not provided [RCV000684655] Chr1:150853044..154647786 [GRCh37]
Chr1:1q21.3
pathogenic
GRCh37/hg19 1p36.33-q44(chr1:47851-249228449)x3 copy number gain not provided [RCV000736295] Chr1:47851..249228449 [GRCh37]
Chr1:1p36.33-q44
pathogenic
GRCh37/hg19 1p36.33-q44(chr1:82154-249218992)x3 copy number gain not provided [RCV000736305] Chr1:82154..249218992 [GRCh37]
Chr1:1p36.33-q44
pathogenic
GRCh37/hg19 1q21.3(chr1:151850071-152295520)x3 copy number gain not provided [RCV000846163] Chr1:151850071..152295520 [GRCh37]
Chr1:1q21.3
uncertain significance
GRCh37/hg19 1q21.3(chr1:152000477-152223996)x1 copy number loss not provided [RCV001005139] Chr1:152000477..152223996 [GRCh37]
Chr1:1q21.3
uncertain significance
GRCh37/hg19 1q21.3(chr1:151798754-152306536)x3 copy number gain not provided [RCV001005138] Chr1:151798754..152306536 [GRCh37]
Chr1:1q21.3
uncertain significance
NC_000001.10:g.(?_130980840)_(248900000_?)dup duplication Gastrointestinal stromal tumor [RCV001300221]|Parathyroid carcinoma [RCV001341077] Chr1:130980840..248900000 [GRCh37]
Chr1:1q12-44
uncertain significance

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:10488 AgrOrtholog
COSMIC S100A11 COSMIC
Ensembl Genes ENSG00000163191 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSP00000271638 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000271638 ENTREZGENE, UniProtKB/Swiss-Prot
GTEx ENSG00000163191 GTEx
HGNC ID HGNC:10488 ENTREZGENE
Human Proteome Map S100A11 Human Proteome Map
InterPro EF-hand-dom_pair UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  S100/CaBP-9k_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  S100_Ca-bd_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  S100A11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:6282 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 6282 ENTREZGENE
OMIM 603114 OMIM
PANTHER PTHR11639:SF60 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam EF-hand_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  S_100 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA34900 PharmGKB
PROSITE EF_HAND_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  S100_CABP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART EFh UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  S_100 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt P31949 ENTREZGENE, UniProtKB/Swiss-Prot
  V9HWH9 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q5VTK0 UniProtKB/Swiss-Prot