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Gene: ATF5 (activating transcription factor 5) Homo sapiens
Symbol: ATF5
Name: activating transcription factor 5
Description: Exhibits several functions, including DNA-binding transcription factor activity; RNA polymerase II regulatory region sequence-specific DNA binding activity; and tubulin binding activity. Involved in several processes, including fat cell differentiation; regulation of cell cycle process; and regulation of transcription, DNA-templated. Localizes to the centrosome; cytosol; and nucleoplasm; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2-methylcholine.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ATFX; cAMP-dependent transcription factor ATF-5; cyclic AMP-dependent transcription factor ATF-5; FLJ34666; HMFN0395; transcription factor ATFx
Mus musculus (house mouse) : Atf5 (activating transcription factor 5)  MGI  Alliance
Rattus norvegicus (Norway rat) : Atf5 (activating transcription factor 5)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atf5 (activating transcription factor 5)
Pan paniscus (bonobo/pygmy chimpanzee) : ATF5 (activating transcription factor 5)
Canis lupus familiaris (dog) : ATF5 (activating transcription factor 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atf5 (activating transcription factor 5)
Sus scrofa (pig) : ATF5 (activating transcription factor 5)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381949,928,702 - 49,933,936 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371950,431,959 - 50,437,193 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361955,124,272 - 55,129,003 (+)NCBINCBI36hg18NCBI36
Build 341955,124,271 - 55,129,003NCBI
Celera1947,301,474 - 47,306,707 (+)NCBI
Cytogenetic Map19q13.33NCBI
HuRef1946,808,214 - 46,813,450 (+)NCBIHuRef
CHM1_11950,433,787 - 50,439,041 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Candidate Gene Status
Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on ATF5
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1350993
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.