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Gene: MINK1 (misshapen like kinase 1) Homo sapiens
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Symbol: MINK1
Name: misshapen like kinase 1
Description: Exhibits protein serine/threonine kinase activity. Involved in several processes, including actin cytoskeleton reorganization; positive regulation of JNK cascade; and protein autophosphorylation. Localizes to Golgi apparatus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: B55; GCK family kinase MINK; hMINK; hMINKbeta; MAP4K6; MAPK/ERK kinase kinase kinase 6; MEK kinase kinase 6; MEKKK 6; MGC21111; MINK; misshapen-like kinase 1; misshapen/NIK-related kinase; mitogen-activated protein kinase kinase kinase kinase 6; serine/threonine protein kinase; YSK2; ZC3
Orthologs:
Mus musculus (house mouse) : Mink1 (misshapen-like kinase 1 (zebrafish))  MGI  Alliance
Rattus norvegicus (Norway rat) : Mink1 (misshapen-like kinase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mink1 (misshapen like kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MINK1 (misshapen like kinase 1)
Canis lupus familiaris (dog) : MINK1 (misshapen like kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mink1 (misshapen like kinase 1)
Sus scrofa (pig) : MINK1 (misshapen like kinase 1)
Chlorocebus sabaeus (African green monkey) : MINK1 (misshapen like kinase 1)
Heterocephalus glaber (naked mole-rat) : Mink1 (misshapen like kinase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl174,833,340 - 4,898,061 (+)EnsemblGRCh38hg38GRCh38
GRCh38174,833,340 - 4,898,061 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37174,736,635 - 4,801,356 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36174,683,351 - 4,742,135 (+)NCBINCBI36hg18NCBI36
Celera174,751,747 - 4,816,237 (+)NCBI
Cytogenetic Map17p13.2NCBI
HuRef174,624,721 - 4,689,491 (+)NCBIHuRef
CHM1_1174,745,647 - 4,810,633 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on MINK1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1604362
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-03-31
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.