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Gene: ATP2C1 (ATPase secretory pathway Ca2+ transporting 1) Homo sapiens
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Symbol: ATP2C1
Name: ATPase secretory pathway Ca2+ transporting 1
Description: Exhibits ATP binding activity; ATPase-coupled cation transmembrane transporter activity; and metal ion binding activity. Involved in several processes, including calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules; cellular metal ion homeostasis; and metal ion transport. Localizes to Golgi membrane and trans-Golgi network. Implicated in Hailey-Hailey disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ATP-dependent Ca(2+) pump PMR1; ATP2C1A; ATPase 2C1; ATPase, Ca(2+)-sequestering; ATPase, Ca++ transporting, type 2C, member 1; atpase, ca++-sequestering; BCPM; benign chronic pemphigus (Hailey-Hailey disease); calcium-transporting ATPase type 2C member 1; HHD; hSPCA1; HUSSY-28; KIAA1347; PMR1; secretory pathway Ca2+/Mn2+ ATPase 1; SPCA1
Orthologs:
Mus musculus (house mouse) : Atp2c1 (ATPase, Ca++-sequestering)  MGI  Alliance
Rattus norvegicus (Norway rat) : Atp2c1 (ATPase secretory pathway Ca2+ transporting 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atp2c1 (ATPase secretory pathway Ca2+ transporting 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ATP2C1 (ATPase secretory pathway Ca2+ transporting 1)
Canis lupus familiaris (dog) : ATP2C1 (ATPase secretory pathway Ca2+ transporting 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atp2c1 (ATPase secretory pathway Ca2+ transporting 1)
Sus scrofa (pig) : ATP2C1 (ATPase secretory pathway Ca2+ transporting 1)
Chlorocebus sabaeus (African green monkey) : ATP2C1 (ATPase secretory pathway Ca2+ transporting 1)
Heterocephalus glaber (naked mole-rat) : Atp2c1 (ATPase secretory pathway Ca2+ transporting 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl3130,850,595 - 131,016,712 (+)EnsemblGRCh38hg38GRCh38
GRCh383130,850,595 - 131,016,712 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh373130,569,327 - 130,735,556 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363132,096,124 - 132,218,246 (+)NCBINCBI36hg18NCBI36
Build 343132,096,131 - 132,204,690NCBI
Celera3129,038,713 - 129,160,803 (+)NCBI
Cytogenetic Map3q22.1NCBI
HuRef3127,954,018 - 128,119,693 (+)NCBIHuRef
CHM1_13130,532,422 - 130,699,080 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - uncurated

Genomics

Comparative Map Data
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Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
Nomenclature History
 
More on ATP2C1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733912
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-05-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.