(+)-schisandrin B multiple interactions ISO RGD:2482 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP7A1 mRNA] CTD PMID:31150632 (-)-epigallocatechin 3-gallate increases expression ISO RGD:2482 6480464 epigallocatechin gallate results in increased expression of CYP7A1 mRNA, epigallocatechin gallate results in increased expression of CYP7A1 protein CTD PMID:23146761 (24S)-24-hydroxycholesterol increases metabolic processing EXP 6480464 CYP7A1 protein results in increased metabolism of 24-hydroxycholesterol CTD PMID:11013305 (25R)-cholest-5-ene-3beta,26-diol increases metabolic processing ISO RGD:2482 6480464 CYP7A1 protein results in increased metabolism of 27-hydroxycholesterol CTD PMID:10882719 (25R)-cholest-5-ene-3beta,26-diol increases metabolic processing EXP 6480464 CYP7A1 protein results in increased metabolism of 27-hydroxycholesterol CTD PMID:10882719 (E)-thiamethoxam decreases expression EXP 6480464 Thiamethoxam results in decreased expression of CYP7A1 protein CTD PMID:32194361 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane affects expression ISO RGD:10458 6480464 o, p'-DDT affects the expression of CYP7A1 mRNA CTD PMID:18925944 1,2-dichloroethane decreases expression ISO RGD:10458 6480464 ethylene dichloride results in decreased expression of CYP7A1 mRNA CTD PMID:28189721 , PMID:28960355 1,4-dithiothreitol increases activity ISO RGD:2482 6480464 Dithiothreitol results in increased activity of CYP7A1 protein CTD PMID:1175606 1-naphthyl isothiocyanate decreases expression ISO RGD:2482 6480464 1-Naphthylisothiocyanate results in decreased expression of CYP7A1 mRNA, 1-Naphthylisothiocyanate results in decreased expression of CYP7A1 protein CTD PMID:14623915 more ... 1-naphthyl isothiocyanate decreases expression ISO RGD:2482 15090803 1-naphthyl isothiocyanate decreases expression of Cyp7a1 protein in rat liver RGD 1-naphthyl isothiocyanate increases expression ISO RGD:2482 6480464 1-Naphthylisothiocyanate results in increased expression of CYP7A1 mRNA CTD PMID:20551477 more ... 1-naphthyl isothiocyanate decreases expression ISO RGD:10458 6480464 1-Naphthylisothiocyanate results in decreased expression of CYP7A1 mRNA, 1-Naphthylisothiocyanate results in decreased expression of CYP7A1 protein CTD PMID:25655198 more ... 1-naphthyl isothiocyanate multiple interactions ISO RGD:10458 6480464 18alpha-glycyrrhetinic acid inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of CYP7A1 mRNA] more ... CTD PMID:25655198 more ... 1-naphthyl isothiocyanate multiple interactions ISO RGD:2482 6480464 resveratrol inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of CYP7A1 mRNA], resveratrol inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of CYP7A1 protein] CTD PMID:25418378 17alpha-ethynylestradiol multiple interactions ISO RGD:10458 6480464 ESR1 gene mutant form inhibits the reaction [Ethinyl Estradiol results in decreased expression of CYP7A1 mRNA] more ... CTD PMID:16606610 more ... 17alpha-ethynylestradiol decreases activity ISO RGD:2482 6480464 Ethinyl Estradiol results in decreased activity of CYP7A1 protein CTD PMID:11473529 , PMID:9869655 17alpha-ethynylestradiol decreases expression ISO RGD:2482 6480464 Ethinyl Estradiol results in decreased expression of CYP7A1 mRNA CTD PMID:16487557 more ... 17alpha-ethynylestradiol multiple interactions ISO RGD:2482 6480464 3 more ... CTD PMID:12963437 , PMID:16487557 17alpha-ethynylestradiol decreases expression ISO RGD:10458 6480464 Ethinyl Estradiol results in decreased expression of CYP7A1 mRNA CTD PMID:16606610 more ... 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of CYP7A1 mRNA CTD PMID:20106945 1H-pyrazole decreases expression ISO RGD:10458 6480464 pyrazole results in decreased expression of CYP7A1 mRNA CTD PMID:17945193 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:10458 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:23756648 more ... 2,2',4,4'-Tetrabromodiphenyl ether decreases expression ISO RGD:2482 6480464 2 more ... CTD PMID:20056577 , PMID:27291303 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO RGD:10458 6480464 2 more ... CTD PMID:30294300 , PMID:33078840 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of CYP7A1 mRNA CTD PMID:20106945 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:2482 6480464 Tetrachlorodibenzodioxin results in increased expression of CYP7A1 mRNA CTD PMID:32109520 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:10458 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:23756648 more ... 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 [Endosulfan co-treated with Tetrachlorodibenzodioxin] results in decreased expression of CYP7A1 mRNA CTD PMID:26159488 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:2482 6480464 Tetrachlorodibenzodioxin results in decreased expression of CYP7A1 mRNA CTD PMID:16054898 , PMID:21215274 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:10458 6480464 Tetrachlorodibenzodioxin results in decreased expression of CYP7A1 mRNA CTD PMID:19770486 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:10458 6480464 Tetrachlorodibenzodioxin results in increased expression of CYP7A1 mRNA CTD PMID:21095216 2,3,7,8-Tetrachlorodibenzofuran increases expression ISO RGD:10458 6480464 2 more ... CTD PMID:25768209 2,3,7,8-Tetrachlorodibenzofuran increases expression ISO RGD:2482 6480464 2 more ... CTD PMID:32109520 2,4,6-trinitrotoluene affects expression ISO RGD:2482 6480464 Trinitrotoluene affects the expression of CYP7A1 mRNA CTD PMID:21346803 2,4-dinitrotoluene affects expression ISO RGD:2482 6480464 2, 4-dinitrotoluene affects the expression of CYP7A1 mRNA CTD PMID:21346803 2-acetamidofluorene multiple interactions ISO RGD:2482 6480464 [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in decreased expression of CYP7A1 mRNA, [Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in decreased expression of CYP7A1 mRNA CTD PMID:14656948 , PMID:16158176 2-arachidonoylglycerol multiple interactions EXP 6480464 CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP7A1 mRNA] more ... CTD PMID:23894352 2-arachidonoylglycerol increases expression EXP 6480464 glyceryl 2-arachidonate results in increased expression of CYP7A1 mRNA CTD PMID:23894352 2-arachidonoylglycerol increases expression ISO RGD:10458 6480464 glyceryl 2-arachidonate results in increased expression of CYP7A1 mRNA CTD PMID:23894352 , PMID:28095641 2-arachidonoylglycerol multiple interactions ISO RGD:10458 6480464 CNR1 gene mutant form inhibits the reaction [glyceryl 2-arachidonate results in increased expression of CYP7A1 mRNA] CTD PMID:23894352 2-trans,6-trans,10-trans-geranylgeranyl diphosphate multiple interactions ISO RGD:10458 6480464 geranylgeranyl pyrophosphate inhibits the reaction [resveratrol results in increased expression of CYP7A1 mRNA] CTD PMID:22607622 20-hydroxycholesterol increases metabolic processing ISO RGD:2482 6480464 CYP7A1 protein results in increased metabolism of 20-hydroxycholesterol CTD PMID:10882719 20-hydroxycholesterol increases metabolic processing EXP 6480464 CYP7A1 protein results in increased metabolism of 20-hydroxycholesterol CTD PMID:10882719 25-hydroxycholesterol increases metabolic processing EXP 6480464 CYP7A1 protein results in increased metabolism of 25-hydroxycholesterol CTD PMID:10882719 25-hydroxycholesterol increases metabolic processing ISO RGD:2482 6480464 CYP7A1 protein results in increased metabolism of 25-hydroxycholesterol CTD PMID:10882719 26-hydroxycholesterol increases metabolic processing EXP 6480464 CYP7A1 protein results in increased metabolism of 27-hydroxycholesterol CTD PMID:10882719 26-hydroxycholesterol increases metabolic processing ISO RGD:2482 6480464 CYP7A1 protein results in increased metabolism of 27-hydroxycholesterol CTD PMID:10882719 3,3',4,4',5-pentachlorobiphenyl decreases expression EXP 6480464 3 more ... CTD PMID:23146750 3,3',4,4'-tetrachlorobiphenyl multiple interactions ISO RGD:10458 6480464 3 more ... CTD PMID:19467301 3-phenylprop-2-enal increases expression EXP 6480464 cinnamic aldehyde results in increased expression of CYP7A1 mRNA CTD PMID:19000754 7-ketocholesterol decreases activity ISO RGD:2482 6480464 7-ketocholesterol results in decreased activity of CYP7A1 protein CTD PMID:1175606 7alpha-hydroxycholesterol multiple interactions ISO RGD:2482 6480464 [Uranyl Nitrate results in decreased activity of CYP7A1 protein] which results in decreased chemical synthesis of cholest-5-en-3 beta, 7 alpha-diol CTD PMID:20362056 acrylamide increases expression ISO RGD:2482 6480464 Acrylamide results in increased expression of CYP7A1 mRNA CTD PMID:15749267 Actein increases expression ISO RGD:2482 6480464 actein results in increased expression of CYP7A1 mRNA CTD PMID:19527300 aflatoxin B1 affects expression EXP 6480464 Aflatoxin B1 affects the expression of CYP7A1 protein CTD PMID:20106945 aflatoxin B1 decreases expression EXP 6480464 Aflatoxin B1 results in decreased expression of CYP7A1 mRNA CTD PMID:22100608 , PMID:27153756 aflatoxin B1 decreases expression ISO RGD:10458 6480464 Aflatoxin B1 results in decreased expression of CYP7A1 mRNA CTD PMID:19770486 alfacalcidol increases expression ISO RGD:10458 6480464 alfacalcidol results in increased expression of CYP7A1 mRNA CTD PMID:19581390 all-trans-retinoic acid multiple interactions EXP 6480464 2-2-amino-3-methoxyphenyl-4H-1-benzopyran-4-one inhibits the reaction [Tretinoin results in decreased expression of CYP7A1 mRNA] more ... CTD PMID:21274875 , PMID:30709899 all-trans-retinoic acid increases expression ISO RGD:2482 6480464 Tretinoin results in increased expression of CYP7A1 mRNA CTD PMID:24977338 all-trans-retinoic acid multiple interactions ISO RGD:2482 6480464 [Tretinoin co-treated with Ursodeoxycholic Acid] results in decreased expression of CYP7A1 mRNA CTD PMID:21274875 all-trans-retinoic acid decreases expression EXP 6480464 Tretinoin results in decreased expression of CYP7A1 mRNA, Tretinoin results in decreased expression of CYP7A1 protein CTD PMID:21274875 , PMID:30709899 AM-251 multiple interactions ISO RGD:10458 6480464 AM 251 inhibits the reaction [Ethanol results in increased expression of CYP7A1 mRNA] CTD PMID:23894352 , PMID:28095641 amiodarone decreases expression ISO RGD:2482 6480464 Amiodarone results in decreased expression of CYP7A1 mRNA CTD PMID:19224547 ammonium chloride affects expression ISO RGD:2482 6480464 Ammonium Chloride affects the expression of CYP7A1 mRNA CTD PMID:16483693 amphibole asbestos affects expression EXP 6480464 Asbestos, Amphibole affects the expression of CYP7A1 protein CTD PMID:20855422 angelicin decreases expression ISO RGD:2482 6480464 angelicin results in decreased expression of CYP7A1 mRNA, angelicin results in decreased expression of CYP7A1 protein CTD PMID:30597224 anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [Tretinoin results in decreased expression of CYP7A1 mRNA], pyrazolanthrone inhibits the reaction [Tretinoin results in decreased expression of CYP7A1 protein] CTD PMID:30709899 arsane multiple interactions ISO RGD:10458 6480464 [APOE protein affects the susceptibility to Arsenic] which affects the expression of CYP7A1 mRNA CTD PMID:22719926 arsenic atom multiple interactions ISO RGD:10458 6480464 [APOE protein affects the susceptibility to Arsenic] which affects the expression of CYP7A1 mRNA CTD PMID:22719926 atazanavir sulfate multiple interactions EXP 6480464 [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of CYP7A1 mRNA CTD PMID:32152650 atazanavir sulfate decreases expression EXP 6480464 Atazanavir Sulfate results in decreased expression of CYP7A1 mRNA CTD PMID:32152650 atorvastatin calcium increases expression ISO RGD:10458 6480464 Atorvastatin results in increased expression of CYP7A1 mRNA CTD PMID:25278499 atorvastatin calcium multiple interactions ISO RGD:2482 6480464 Atorvastatin inhibits the reaction [Dietary Fats results in decreased expression of CYP7A1 mRNA] CTD PMID:32048413 atrazine increases expression ISO RGD:10458 6480464 Atrazine results in increased expression of CYP7A1 mRNA CTD PMID:22515965 azoxystrobin decreases expression EXP 6480464 azoxystrobin results in decreased expression of CYP7A1 mRNA, azoxystrobin results in decreased expression of CYP7A1 protein CTD PMID:32194361 benzo[a]pyrene decreases expression ISO RGD:10458 6480464 Benzoapyrene results in decreased expression of CYP7A1 mRNA CTD PMID:19770486 benzo[a]pyrene decreases expression EXP 6480464 Benzoapyrene results in decreased expression of CYP7A1 mRNA CTD PMID:32234424 benzo[a]pyrene decreases methylation EXP 6480464 Benzoapyrene results in decreased methylation of CYP7A1 promoter CTD PMID:27901495 benzo[a]pyrene multiple interactions ISO RGD:10458 6480464 [corannulene co-treated with Benzoapyrene] results in increased expression of CYP7A1 mRNA CTD PMID:32417428 benzo[a]pyrene affects expression ISO RGD:2482 6480464 Benzoapyrene affects the expression of CYP7A1 mRNA CTD PMID:22374506 beta-hexachlorocyclohexane increases expression ISO RGD:10458 6480464 beta-hexachlorocyclohexane results in increased expression of CYP7A1 mRNA CTD PMID:28392238 beta-hexachlorocyclohexane increases expression EXP 6480464 beta-hexachlorocyclohexane results in increased expression of CYP7A1 mRNA CTD PMID:28392238 beta-naphthoflavone decreases expression EXP 6480464 beta-Naphthoflavone results in decreased expression of CYP7A1 mRNA CTD PMID:22258563 bezafibrate decreases activity EXP 6480464 Bezafibrate results in decreased activity of CYP7A1 protein CTD PMID:2044640 bezafibrate decreases activity ISO RGD:2482 6480464 Bezafibrate results in decreased activity of CYP7A1 protein CTD PMID:2044640 bezafibrate decreases expression EXP 6480464 Bezafibrate results in decreased expression of CYP7A1 mRNA CTD PMID:14685799 bilirubin IXalpha multiple interactions ISO RGD:2482 6480464 [Manganese co-treated with Bilirubin] results in decreased activity of CYP7A1 protein CTD PMID:12700418 bilirubin IXalpha decreases activity ISO RGD:2482 6480464 Bilirubin results in decreased activity of CYP7A1 protein CTD PMID:12700418 bis(2-ethylhexyl) phthalate increases expression ISO RGD:10458 6480464 Diethylhexyl Phthalate results in increased expression of CYP7A1 mRNA CTD PMID:19850644 bis(2-ethylhexyl) phthalate increases expression ISO RGD:2482 6480464 Diethylhexyl Phthalate results in increased expression of CYP7A1 mRNA CTD PMID:29945229 bis(2-ethylhexyl) phthalate multiple interactions ISO RGD:10458 6480464 [APOE gene mutant form results in increased susceptibility to Diethylhexyl Phthalate] which results in decreased expression of CYP7A1 protein more ... CTD PMID:19850644 more ... bisphenol A increases expression ISO RGD:10458 6480464 bisphenol A results in increased expression of CYP7A1 mRNA CTD PMID:17706920 , PMID:27502578 bisphenol A affects expression ISO RGD:2482 6480464 bisphenol A affects the expression of CYP7A1 mRNA CTD PMID:30903817 bisphenol A decreases expression ISO RGD:2482 6480464 bisphenol A results in decreased expression of CYP7A1 mRNA CTD PMID:25181051 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of CYP7A1 mRNA CTD PMID:23146750 bisphenol A multiple interactions ISO RGD:10458 6480464 [bisphenol A co-treated with Diethylhexyl Phthalate co-treated with Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:17706920 more ... bosentan decreases expression EXP 6480464 Bosentan results in decreased expression of CYP7A1 mRNA CTD PMID:29761207 bromobenzene increases expression ISO RGD:2482 6480464 bromobenzene results in increased expression of CYP7A1 mRNA CTD PMID:32479839 cadmium dichloride decreases methylation ISO RGD:2482 6480464 Cadmium Chloride results in decreased methylation of CYP7A1 promoter CTD PMID:22457795 calcipotriol multiple interactions EXP 6480464 calcipotriene inhibits the reaction [VDR protein affects the expression of CYP7A1 protein] CTD PMID:30419252 calcipotriol decreases expression EXP 6480464 calcipotriene results in decreased expression of CYP7A1 protein CTD PMID:30419252 calcitriol multiple interactions EXP 6480464 2-2-amino-3-methoxyphenyl-4H-1-benzopyran-4-one inhibits the reaction [Calcitriol results in decreased expression of CYP7A1 mRNA] more ... CTD PMID:19106115 , PMID:20371703 calcitriol decreases expression EXP 6480464 Calcitriol results in decreased expression of CYP7A1 mRNA CTD PMID:20371703 carbendazim decreases expression EXP 6480464 carbendazim results in decreased expression of CYP7A1 mRNA, carbendazim results in decreased expression of CYP7A1 protein CTD PMID:32194361 carbon nanotube affects expression ISO RGD:10458 6480464 Nanotubes, Carbon analog affects the expression of CYP7A1 mRNA CTD PMID:25620056 carbon nanotube decreases expression ISO RGD:10458 6480464 Nanotubes, Carbon results in decreased expression of CYP7A1 mRNA CTD PMID:25620056 chenodeoxycholic acid decreases expression EXP 6480464 Chenodeoxycholic Acid results in decreased expression of CYP7A1 mRNA CTD PMID:19072826 more ... chenodeoxycholic acid decreases expression ISO RGD:10458 6480464 Chenodeoxycholic Acid results in decreased expression of CYP7A1 mRNA CTD PMID:19072826 more ... chenodeoxycholic acid multiple interactions EXP 6480464 [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of CYP7A1 mRNA more ... CTD PMID:17963371 , PMID:32152650 chenodeoxycholic acid multiple interactions ISO RGD:2482 6480464 [Chenodeoxycholic Acid co-treated with Ketoconazole] results in decreased expression of CYP7A1 mRNA, [Chenodeoxycholic Acid results in increased expression of FGF19 protein] which results in decreased expression of CYP7A1 protein CTD PMID:20835427 , PMID:30985903 chenodeoxycholic acid multiple interactions ISO RGD:10458 6480464 NR1H4 mutant form inhibits the reaction [Chenodeoxycholic Acid results in decreased expression of CYP7A1 mRNA] CTD PMID:19072826 chitosan multiple interactions ISO RGD:2482 6480464 Chitosan inhibits the reaction [Dietary Fats results in increased expression of CYP7A1 mRNA], Fish Oils promotes the reaction [Chitosan inhibits the reaction [Dietary Fats results in increased expression of CYP7A1 mRNA]] CTD PMID:28987369 chlormequat chloride increases expression EXP 6480464 Chlormequat results in increased expression of CYP7A1 protein CTD PMID:32194361 chloroquine multiple interactions EXP 6480464 Chloroquine promotes the reaction [CYP7A1 protein results in increased expression of MAP1LC3B protein modified form], CYP7A1 mRNA promotes the reaction [Chloroquine results in increased expression of MAP1LC3B protein modified form] CTD PMID:28275691 chlorpyrifos decreases expression EXP 6480464 Chlorpyrifos results in decreased expression of CYP7A1 mRNA, Chlorpyrifos results in decreased expression of CYP7A1 protein CTD PMID:32194361 cholate decreases expression EXP 6480464 Cholates results in decreased expression of CYP7A1 mRNA CTD PMID:14684751 cholate decreases expression ISO RGD:10458 6480464 Cholates results in decreased expression of CYP7A1 CTD PMID:10809780 cholesta-5,7-dien-3beta-ol decreases activity ISO RGD:2482 6480464 7-dehydrocholesterol results in decreased activity of CYP7A1 protein CTD PMID:1175606 cholesterol affects metabolic processing EXP 6480464 CYP7A1 protein affects the metabolism of Cholesterol CTD PMID:15696852 cholesterol multiple interactions EXP 6480464 CYP7A1 mRNA inhibits the reaction [Cholesterol results in increased phosphorylation of EIF4EBP1 protein] more ... CTD PMID:28275691 , PMID:30709899 cholesterol increases metabolic processing ISO RGD:2482 6480464 CYP7A1 protein results in increased metabolism of Cholesterol CTD PMID:1175606 cholesterol increases expression ISO RGD:2482 6480464 Cholesterol results in increased expression of CYP7A1 mRNA CTD PMID:21535835 cholesterol multiple interactions ISO RGD:2482 6480464 turmeric extract promotes the reaction [Cholesterol results in increased expression of CYP7A1 mRNA] CTD PMID:21535835 cholesterol increases metabolic processing EXP 6480464 CYP7A1 protein results in increased metabolism of Cholesterol CTD PMID:11013305 , PMID:7925343 cholic acid decreases expression EXP 6480464 Cholic Acid results in decreased expression of CYP7A1 mRNA CTD PMID:25055961 cholic acid decreases expression ISO RGD:10458 6480464 Cholic Acid results in decreased expression of CYP7A1 mRNA CTD PMID:12072388 more ... cholic acid multiple interactions ISO RGD:10458 6480464 [Cholic Acid binds to and results in increased activity of NR1H4 protein] which results in decreased expression of CYP7A1 mRNA CTD PMID:22540009 cholic acid multiple interactions ISO RGD:2482 6480464 [Cholesterol more ... CTD PMID:14684380 chrysophanol increases expression ISO RGD:2482 6480464 chrysophanic acid results in increased expression of CYP7A1 mRNA, chrysophanic acid results in increased expression of CYP7A1 protein CTD PMID:28161596 ciguatoxin CTX1B affects expression ISO RGD:10458 6480464 Ciguatoxins affects the expression of CYP7A1 mRNA CTD PMID:18353800 clofibrate decreases expression ISO RGD:10458 6480464 Clofibrate results in decreased expression of CYP7A1 mRNA CTD PMID:17585979 clofibrate decreases expression ISO RGD:2482 6480464 Clofibrate results in decreased expression of CYP7A1 mRNA CTD PMID:19224547 clofibrate increases expression ISO RGD:10458 6480464 Clofibrate results in increased expression of CYP7A1 mRNA CTD PMID:28973556 cobalt atom increases expression ISO RGD:10458 6480464 Cobalt results in increased expression of CYP7A1 mRNA CTD PMID:22147119 copper atom decreases expression ISO RGD:10458 6480464 Copper results in decreased expression of CYP7A1 mRNA CTD PMID:17205981 copper atom decreases activity ISO RGD:2482 6480464 Copper results in decreased activity of CYP7A1 protein CTD PMID:1175606 copper atom increases expression ISO RGD:2482 6480464 Copper deficiency results in increased expression of CYP7A1 mRNA CTD PMID:11110846 copper(0) decreases expression ISO RGD:10458 6480464 Copper results in decreased expression of CYP7A1 mRNA CTD PMID:17205981 copper(0) decreases activity ISO RGD:2482 6480464 Copper results in decreased activity of CYP7A1 protein CTD PMID:1175606 copper(0) increases expression ISO RGD:2482 6480464 Copper deficiency results in increased expression of CYP7A1 mRNA CTD PMID:11110846 copper(II) sulfate decreases expression EXP 6480464 Copper Sulfate results in decreased expression of CYP7A1 mRNA CTD PMID:19549813 coumarin decreases expression ISO RGD:2482 6480464 coumarin results in decreased expression of CYP7A1 mRNA CTD PMID:18480146 cyclosporin A decreases expression EXP 6480464 Cyclosporine results in decreased expression of CYP7A1 mRNA, Cyclosporine results in decreased expression of CYP7A1 protein CTD PMID:20106945 more ... cyclosporin A multiple interactions EXP 6480464 [Cyclosporine co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of CYP7A1 mRNA, [Cyclosporine results in decreased expression of CYP7A1 protein] which affects the abundance of Cholic Acids CTD PMID:26198044 , PMID:32152650 cyclosporin A increases expression ISO RGD:10458 6480464 Cyclosporine results in increased expression of CYP7A1 mRNA CTD PMID:19770486 cyproconazole multiple interactions ISO RGD:2482 6480464 [cyproconazole co-treated with epoxiconazole] results in increased expression of CYP7A1 mRNA CTD PMID:29038839 cyproconazole decreases expression EXP 6480464 cyproconazole results in decreased expression of CYP7A1 mRNA CTD PMID:29995386 cyprodinil decreases expression EXP 6480464 cyprodinil results in decreased expression of CYP7A1 mRNA, cyprodinil results in decreased expression of CYP7A1 protein CTD PMID:32194361 cysteamine increases activity ISO RGD:2482 6480464 Cysteamine results in increased activity of CYP7A1 protein CTD PMID:1175606 DDE increases expression ISO RGD:10458 6480464 Dichlorodiphenyl Dichloroethylene results in increased expression of CYP7A1 mRNA CTD PMID:28392238 DDE increases expression EXP 6480464 Dichlorodiphenyl Dichloroethylene results in increased expression of CYP7A1 mRNA CTD PMID:28392238 deoxycholic acid decreases expression EXP 6480464 Deoxycholic Acid results in decreased expression of CYP7A1 mRNA CTD PMID:14684751 , PMID:25055961 deoxycholic acid multiple interactions EXP 6480464 [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of CYP7A1 mRNA more ... CTD PMID:32152650 deoxycholic acid decreases expression ISO RGD:10458 6480464 Deoxycholic Acid results in decreased expression of CYP7A1 mRNA CTD PMID:20671298 more ... deoxycholic acid decreases activity ISO RGD:2482 6480464 Deoxycholic Acid results in decreased activity of CYP7A1 protein CTD PMID:1175606 deoxycholic acid multiple interactions ISO RGD:10458 6480464 [Deoxycholic Acid results in increased activity of NR1H4 protein] which results in increased expression of CYP7A1 mRNA, SLCO1A1 protein affects the susceptibility to [Deoxycholic Acid results in decreased expression of CYP7A1 mRNA] CTD PMID:21914718 , PMID:22531947 dexamethasone increases expression ISO RGD:2482 6480464 Dexamethasone results in increased expression of CYP7A1 mRNA CTD PMID:15965953 , PMID:32599024 dexamethasone decreases expression ISO RGD:2482 6480464 Dexamethasone results in decreased expression of CYP7A1 mRNA CTD PMID:20888898 dextran sulfate decreases expression ISO RGD:10458 6480464 Dextran Sulfate results in decreased expression of CYP7A1 mRNA CTD PMID:27580383 diallyl trisulfide decreases expression EXP 6480464 diallyl trisulfide results in decreased expression of CYP7A1 mRNA CTD PMID:16382202 dichloroacetic acid increases expression ISO RGD:10458 6480464 Dichloroacetic Acid results in increased expression of CYP7A1 mRNA CTD PMID:28962523 diclofenac increases expression ISO RGD:10458 6480464 Diclofenac results in increased expression of CYP7A1 mRNA CTD PMID:26934552 dicrotophos decreases expression EXP 6480464 dicrotophos results in decreased expression of CYP7A1 mRNA CTD PMID:28302478 difenoconazole decreases expression EXP 6480464 difenoconazole results in decreased expression of CYP7A1 mRNA, difenoconazole results in decreased expression of CYP7A1 protein CTD PMID:32194361 dihydroartemisinin multiple interactions ISO RGD:2482 15036816 Dihydroartemisinin inhibits the reaction [ethanol increases expression of Cyp7a1 protein in liver] RGD Diisodecyl phthalate increases expression ISO RGD:10458 6480464 diisodecyl phthalate results in increased expression of CYP7A1 mRNA CTD PMID:25270620 dimethomorph decreases expression EXP 6480464 dimethomorph results in decreased expression of CYP7A1 mRNA, dimethomorph results in decreased expression of CYP7A1 protein CTD PMID:32194361 dimethyl sulfoxide increases expression ISO RGD:2482 15092090 DMSO increases expression of Cyp7a1 mRNA in rat liver, reaction inhibited by INT-767 RGD diosgenin multiple interactions ISO RGD:2482 6480464 [Ethinyl Estradiol co-treated with Diosgenin] results in increased expression of CYP7A1 mRNA CTD PMID:12963437 dioxygen decreases expression EXP 6480464 Oxygen deficiency results in decreased expression of CYP7A1 mRNA CTD PMID:19695866 elemental selenium multiple interactions ISO RGD:2482 6480464 [Magnesium co-treated with Selenium co-treated with Dietary Fats] results in increased expression of CYP7A1 mRNA CTD PMID:30031400 emodin decreases expression ISO RGD:2482 6480464 Emodin results in decreased expression of CYP7A1 mRNA, Emodin results in decreased expression of CYP7A1 protein CTD PMID:28161596 endosulfan multiple interactions EXP 6480464 [Endosulfan co-treated with Tetrachlorodibenzodioxin] results in decreased expression of CYP7A1 mRNA CTD PMID:26159488 endosulfan decreases expression ISO RGD:2482 6480464 Endosulfan results in decreased expression of CYP7A1 mRNA CTD PMID:29391264 endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of CYP7A1 mRNA CTD PMID:26159488 enilconazole decreases expression ISO RGD:10458 6480464 enilconazole results in decreased expression of CYP7A1 mRNA CTD PMID:29451352 enilconazole decreases expression EXP 6480464 enilconazole results in decreased expression of CYP7A1 mRNA, enilconazole results in decreased expression of CYP7A1 protein CTD PMID:32194361 , PMID:32201337 Epomediol increases activity ISO RGD:2482 6480464 epomediol results in increased activity of CYP7A1 protein CTD PMID:10961725 , PMID:11473529 Epomediol increases expression ISO RGD:2482 6480464 epomediol results in increased expression of CYP7A1 mRNA CTD PMID:11473529 epoxiconazole multiple interactions ISO RGD:2482 6480464 [cyproconazole co-treated with epoxiconazole] results in increased expression of CYP7A1 mRNA CTD PMID:29038839 epoxiconazole decreases expression EXP 6480464 epoxiconazole results in decreased expression of CYP7A1 mRNA CTD PMID:32194361 ethanol multiple interactions ISO RGD:2482 6480464 [Fish Oils co-treated with Ethanol] results in increased expression of CYP7A1 mRNA CTD PMID:17347304 ethanol increases expression ISO RGD:2482 15036816 ethanol increases expression of Cyp7a1 protein in liver RGD ethanol increases expression ISO RGD:10458 6480464 Ethanol results in increased expression of CYP7A1 mRNA, Ethanol results in increased expression of CYP7A1 protein CTD PMID:19167417 more ... ethanol multiple interactions ISO RGD:10458 6480464 AM 251 inhibits the reaction [Ethanol results in increased expression of CYP7A1 mRNA] more ... CTD PMID:23894352 , PMID:28095641 ethoprophos decreases expression EXP 6480464 ethoprophos results in decreased expression of CYP7A1 mRNA, ethoprophos results in decreased expression of CYP7A1 protein CTD PMID:32194361 fenbuconazole decreases expression EXP 6480464 fenbuconazole results in decreased expression of CYP7A1 mRNA CTD PMID:15942997 fenhexamid decreases expression EXP 6480464 N-2, 3-dichloro-4-hydroxyphenyl-1-methylcyclohexanecarboxamide results in decreased expression of CYP7A1 mRNA CTD PMID:32194361 fenofibrate multiple interactions ISO RGD:2482 6480464 [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CYP7A1 mRNA CTD PMID:18253720 fenofibrate decreases expression EXP 6480464 Fenofibrate results in decreased expression of CYP7A1 mRNA CTD PMID:14685799 fenpyroximate decreases expression EXP 6480464 fenpyroximate results in decreased expression of CYP7A1 mRNA, fenpyroximate results in decreased expression of CYP7A1 protein CTD PMID:32194361 fenvalerate decreases expression ISO RGD:2482 6480464 fenvalerate results in decreased expression of CYP7A1 mRNA CTD PMID:30307764 fipronil decreases expression EXP 6480464 fipronil results in decreased expression of CYP7A1 protein CTD PMID:32194361 fipronil increases expression EXP 6480464 fipronil results in increased expression of CYP7A1 mRNA CTD PMID:32194361 fisetin multiple interactions ISO RGD:2482 6480464 fisetin inhibits the reaction [Dietary Fats results in increased expression of CYP7A1 mRNA] CTD PMID:23524313 flavonoids increases expression ISO RGD:2482 6480464 Flavonoids results in increased expression of CYP7A1 mRNA CTD PMID:18035473 fludioxonil decreases expression EXP 6480464 fludioxonil results in decreased expression of CYP7A1 protein CTD PMID:32194361 flusilazole decreases expression EXP 6480464 flusilazole results in decreased expression of CYP7A1 mRNA CTD PMID:32194361 flutamide decreases expression ISO RGD:2482 6480464 Flutamide results in decreased expression of CYP7A1 mRNA CTD PMID:24136188 fluxapyroxad decreases expression EXP 6480464 fluxapyroxad results in decreased expression of CYP7A1 mRNA, fluxapyroxad results in decreased expression of CYP7A1 protein CTD PMID:32194361 furan decreases expression ISO RGD:2482 6480464 furan results in decreased expression of CYP7A1 mRNA CTD PMID:15120968 furan decreases expression ISO RGD:10458 6480464 furan results in decreased expression of CYP7A1 mRNA CTD PMID:32251705 furan multiple interactions ISO RGD:10458 6480464 rhodioloside inhibits the reaction [furan results in decreased expression of CYP7A1 mRNA] CTD PMID:32251705 furan increases expression ISO RGD:2482 6480464 furan results in increased expression of CYP7A1 mRNA CTD PMID:25539665 gemfibrozil decreases expression EXP 6480464 Gemfibrozil results in decreased expression of CYP7A1 mRNA CTD PMID:14685799 genistein multiple interactions ISO RGD:2482 6480464 [Genistein co-treated with Methoxychlor] results in decreased expression of CYP7A1 mRNA CTD PMID:21782745 Gentiopicrin decreases expression ISO RGD:2482 15045612 Gentiopicrin decreases expression of Cyp7a1 mRNA in rat ANIT induced cholestatic liver RGD glycochenodeoxycholic acid multiple interactions EXP 6480464 [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of CYP7A1 mRNA more ... CTD PMID:32152650 glycocholic acid multiple interactions EXP 6480464 [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of CYP7A1 mRNA more ... CTD PMID:32152650 glycodeoxycholic acid multiple interactions EXP 6480464 [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of CYP7A1 mRNA more ... CTD PMID:32152650 glycyrrhetinate multiple interactions ISO RGD:10458 6480464 18alpha-glycyrrhetinic acid inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of CYP7A1 mRNA] CTD PMID:28549656 glycyrrhetinic acid multiple interactions ISO RGD:10458 6480464 18alpha-glycyrrhetinic acid inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of CYP7A1 mRNA] CTD PMID:28549656 glycyrrhizinic acid decreases expression ISO RGD:10458 6480464 Glycyrrhizic Acid results in decreased expression of CYP7A1 mRNA CTD PMID:22982774 glycyrrhizinic acid multiple interactions ISO RGD:10458 6480464 Glycyrrhizic Acid inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of CYP7A1 mRNA] CTD PMID:28549656 guggulsterone multiple interactions ISO RGD:2482 15036816 Z-guggulsterone reverses the reaction [Dihydroartemisinin inhibits the reaction [ethanol increases expression of Cyp7a1 protein in liver]] RGD guggulsterone multiple interactions ISO RGD:10458 6480464 pregna-4 more ... CTD PMID:25655198 , PMID:29660435 guggulsterone multiple interactions EXP 6480464 pregna-4 more ... CTD PMID:12705905 GW 3965 increases expression ISO RGD:2482 6480464 GW 3965 results in increased expression of CYP7A1 mRNA CTD PMID:17420776 GW 4064 decreases expression EXP 6480464 GW 4064 results in decreased expression of CYP7A1 mRNA CTD PMID:31437187 GW 4064 decreases expression ISO RGD:2482 6480464 GW 4064 results in decreased expression of CYP7A1 mRNA CTD PMID:14623915 , PMID:15644430 GW 4064 decreases expression ISO RGD:10458 6480464 GW 4064 results in decreased expression of CYP7A1 mRNA CTD PMID:27609522 GW 4064 multiple interactions ISO RGD:10458 6480464 [GW 4064 binds to and results in increased activity of NR1H4 protein] which results in decreased expression of CYP7A1 mRNA more ... CTD PMID:22467244 , PMID:22540009 Heliotrine decreases expression EXP 6480464 heliotrine results in decreased expression of CYP7A1 mRNA CTD PMID:26100227 hyperforin decreases expression EXP 6480464 hyperforin results in decreased expression of CYP7A1 mRNA CTD PMID:24259679 imipenem hydrate multiple interactions ISO RGD:10458 6480464 [Vancomycin co-treated with Imipenem] results in decreased expression of CYP7A1 mRNA CTD PMID:24657338 indoxyl sulfate decreases expression EXP 6480464 Indican results in decreased expression of CYP7A1 mRNA CTD PMID:30639138 iprodione decreases expression EXP 6480464 iprodione results in decreased expression of CYP7A1 protein CTD PMID:32194361 isoniazide increases expression ISO RGD:2482 6480464 Isoniazid results in increased expression of CYP7A1 mRNA CTD PMID:25331106 , PMID:32673658 isoniazide multiple interactions EXP 6480464 [Isoniazid co-treated with Vitamin B 6] results in increased expression of CYP7A1 mRNA CTD PMID:32673658 isoniazide multiple interactions ISO RGD:2482 6480464 [Lipopolysaccharides co-treated with Isoniazid] results in increased expression of CYP7A1 mRNA, obeticholic acid inhibits the reaction [Isoniazid results in increased expression of CYP7A1 mRNA] CTD PMID:25331106 , PMID:32673658 ketoconazole multiple interactions ISO RGD:2482 6480464 [Chenodeoxycholic Acid co-treated with Ketoconazole] results in decreased expression of CYP7A1 mRNA CTD PMID:30985903 kojic acid multiple interactions ISO RGD:10458 6480464 [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CYP7A1 mRNA, [Diethylnitrosamine co-treated with kojic acid] results in increased expression of CYP7A1 mRNA CTD PMID:17917374 L-1,4-dithiothreitol increases activity ISO RGD:2482 6480464 Dithiothreitol results in increased activity of CYP7A1 protein CTD PMID:1175606 L-ascorbic acid multiple interactions ISO RGD:10458 6480464 [Diethylnitrosamine co-treated with Ascorbic Acid] results in increased expression of CYP7A1 mRNA, [Diethylnitrosamine co-treated with kojic acid co-treated with Ascorbic Acid] results in increased expression of CYP7A1 mRNA CTD PMID:17917374 Lasiocarpine decreases expression EXP 6480464 lasiocarpine results in decreased expression of CYP7A1 mRNA CTD PMID:32234424 lead nitrate decreases expression ISO RGD:10458 6480464 lead nitrate results in decreased expression of CYP7A1 mRNA CTD PMID:16049268 , PMID:22293356 lead nitrate multiple interactions ISO RGD:10458 6480464 [IL1A gene mutant form co-treated with IL1B gene mutant form] inhibits the reaction [lead nitrate results in decreased expression of CYP7A1 mRNA] CTD PMID:22293356 lead nitrate decreases expression ISO RGD:2482 6480464 lead nitrate results in decreased expression of CYP7A1 mRNA CTD PMID:15475176 lead(0) multiple interactions ISO RGD:2482 6480464 puerarin affects the reaction [Lead affects the expression of CYP7A1] CTD PMID:22001170 lead(0) decreases activity ISO RGD:2482 6480464 Lead results in decreased activity of CYP7A1 protein CTD PMID:1175606 lead(0) affects expression ISO RGD:2482 6480464 Lead affects the expression of CYP7A1 CTD PMID:22001170 lead(2+) affects expression ISO RGD:2482 6480464 Lead affects the expression of CYP7A1 CTD PMID:22001170 lead(2+) decreases activity ISO RGD:2482 6480464 Lead results in decreased activity of CYP7A1 protein CTD PMID:1175606 lead(2+) multiple interactions ISO RGD:2482 6480464 puerarin affects the reaction [Lead affects the expression of CYP7A1] CTD PMID:22001170 lipopolysaccharide multiple interactions EXP 6480464 [usnic acid co-treated with Lipopolysaccharides] results in decreased expression of CYP7A1 mRNA CTD PMID:22777745 lipopolysaccharide multiple interactions ISO RGD:2482 6480464 [Lipopolysaccharides co-treated with Isoniazid] results in increased expression of CYP7A1 mRNA CTD PMID:25331106 lipopolysaccharide increases expression ISO RGD:2482 6480464 Lipopolysaccharides results in increased expression of CYP7A1 mRNA CTD PMID:25331106 lithocholic acid decreases expression EXP 6480464 Lithocholic Acid results in decreased expression of CYP7A1 mRNA CTD PMID:25055961 lithocholic acid decreases expression ISO RGD:10458 6480464 Lithocholic Acid results in decreased expression of CYP7A1 mRNA CTD PMID:16436656 more ... lithocholic acid multiple interactions EXP 6480464 [Lithocholic Acid analog binds to and results in increased activity of NR1H4 protein] which results in decreased expression of CYP7A1 mRNA, [Lithocholic Acid binds to and results in increased activity of NR1H4 protein] which results in decreased expression of CYP7A1 mRNA CTD PMID:17963371 lithocholic acid decreases activity ISO RGD:2482 6480464 Lithocholic Acid results in decreased activity of CYP7A1 protein CTD PMID:1175606 lithocholic acid decreases expression ISO RGD:2482 6480464 Lithocholic Acid results in decreased expression of CYP7A1 mRNA CTD PMID:20888898 lithocholic acid multiple interactions ISO RGD:10458 6480464 1 more ... CTD PMID:19196849 more ... magnesium atom multiple interactions ISO RGD:2482 6480464 [Magnesium co-treated with Selenium co-treated with Dietary Fats] results in increased expression of CYP7A1 mRNA CTD PMID:30031400 maneb decreases expression EXP 6480464 Maneb results in decreased expression of CYP7A1 mRNA CTD PMID:32194361 manganese atom multiple interactions ISO RGD:2482 6480464 [Manganese co-treated with Bilirubin] results in decreased activity of CYP7A1 protein CTD PMID:12700418 manganese atom increases activity ISO RGD:2482 6480464 Manganese results in increased activity of CYP7A1 protein CTD PMID:12700418 manganese(0) multiple interactions ISO RGD:2482 6480464 [Manganese co-treated with Bilirubin] results in decreased activity of CYP7A1 protein CTD PMID:12700418 manganese(0) increases activity ISO RGD:2482 6480464 Manganese results in increased activity of CYP7A1 protein CTD PMID:12700418 melatonin multiple interactions ISO RGD:10458 6480464 Melatonin inhibits the reaction [Ethanol results in increased expression of CYP7A1 mRNA] more ... CTD PMID:28095641 melatonin decreases expression ISO RGD:10458 6480464 Melatonin results in decreased expression of CYP7A1 mRNA CTD PMID:28095641 mercaptoethanol increases activity ISO RGD:2482 6480464 Mercaptoethanol results in increased activity of CYP7A1 protein CTD PMID:1175606 mercury atom decreases activity ISO RGD:2482 6480464 Mercury results in decreased activity of CYP7A1 protein CTD PMID:1175606 mercury(0) decreases activity ISO RGD:2482 6480464 Mercury results in decreased activity of CYP7A1 protein CTD PMID:1175606 metacetamol decreases expression ISO RGD:10458 6480464 3-hydroxyacetanilide results in decreased expression of CYP7A1 mRNA CTD PMID:18544908 metalaxyl decreases expression EXP 6480464 metalaxyl results in decreased expression of CYP7A1 protein CTD PMID:32194361 metformin multiple interactions ISO RGD:2482 6480464 Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 mRNA], Metformin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 protein] CTD PMID:31100278 metformin affects expression ISO RGD:2482 6480464 Metformin affects the expression of CYP7A1 mRNA CTD PMID:31324951 methapyrilene decreases expression ISO RGD:2482 6480464 Methapyrilene results in decreased expression of CYP7A1 mRNA CTD PMID:30467583 methotrexate decreases expression ISO RGD:2482 6480464 Methotrexate results in decreased expression of CYP7A1 mRNA CTD PMID:15120968 methotrexate decreases expression EXP 6480464 Methotrexate results in decreased expression of CYP7A1 mRNA CTD PMID:24449571 methoxsalen increases expression ISO RGD:2482 6480464 Methoxsalen results in increased expression of CYP7A1 protein CTD PMID:28552422 methoxsalen multiple interactions EXP 6480464 Methoxsalen affects the reaction [VDR protein affects the expression of CYP7A1 protein] CTD PMID:30419252 methoxsalen decreases expression EXP 6480464 Methoxsalen results in decreased expression of CYP7A1 protein CTD PMID:30419252 methoxsalen decreases expression ISO RGD:2482 6480464 Methoxsalen results in decreased expression of CYP7A1 mRNA CTD PMID:28552422 methoxychlor multiple interactions ISO RGD:2482 6480464 [Genistein co-treated with Methoxychlor] results in decreased expression of CYP7A1 mRNA CTD PMID:21782745 monocrotaline multiple interactions ISO RGD:10458 6480464 [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP7A1 mRNA CTD PMID:21224054 monocrotophos increases expression ISO RGD:2482 6480464 Monocrotophos results in increased expression of CYP7A1 mRNA CTD PMID:32267039 monosodium L-glutamate increases expression ISO RGD:10458 6480464 Sodium Glutamate results in increased expression of CYP7A1 mRNA CTD PMID:19001666 , PMID:20111022 monosodium L-glutamate multiple interactions ISO RGD:10458 6480464 [Sodium Glutamate co-treated with High Fructose Corn Syrup] results in increased expression of CYP7A1 mRNA CTD PMID:20111022 N-nitrosodiethylamine multiple interactions ISO RGD:10458 6480464 [Diethylnitrosamine co-treated with Ascorbic Acid] results in increased expression of CYP7A1 mRNA more ... CTD PMID:17917374 more ... N-nitrosodiethylamine decreases expression ISO RGD:2482 6480464 Diethylnitrosamine results in decreased expression of CYP7A1 mRNA CTD PMID:19638242 N-nitrosodiethylamine increases expression ISO RGD:10458 6480464 Diethylnitrosamine results in increased expression of CYP7A1 mRNA CTD PMID:18691550 N-nitrosodiethylamine multiple interactions ISO RGD:2482 6480464 [2-Acetylaminofluorene co-treated with Diethylnitrosamine] results in decreased expression of CYP7A1 mRNA more ... CTD PMID:14656948 more ... N-Nitrosopyrrolidine decreases expression EXP 6480464 N-Nitrosopyrrolidine results in decreased expression of CYP7A1 mRNA CTD PMID:32234424 nefazodone decreases expression EXP 6480464 nefazodone results in decreased expression of CYP7A1 mRNA CTD PMID:32152650 nefazodone multiple interactions EXP 6480464 [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of CYP7A1 mRNA CTD PMID:32152650 nickel atom increases expression ISO RGD:10458 6480464 Nickel results in increased expression of CYP7A1 mRNA CTD PMID:18922574 O-methyleugenol decreases expression EXP 6480464 methyleugenol results in decreased expression of CYP7A1 mRNA CTD PMID:32234424 obeticholic acid decreases expression ISO RGD:2482 15045602 obeticholic acid decreases expression of CYP7a1 mRNA in liver in porcine serum induced model of cirrhosis in rat RGD obeticholic acid multiple interactions ISO RGD:2482 6480464 obeticholic acid inhibits the reaction [Isoniazid results in increased expression of CYP7A1 mRNA] CTD PMID:32673658 obeticholic acid multiple interactions ISO RGD:10458 6480464 obeticholic acid promotes the reaction [1-Naphthylisothiocyanate results in decreased expression of CYP7A1 mRNA] CTD PMID:29660435 obeticholic acid decreases expression ISO RGD:2482 6480464 obeticholic acid results in decreased expression of CYP7A1 mRNA CTD PMID:15644430 obeticholic acid decreases expression EXP 6480464 obeticholic acid results in decreased expression of CYP7A1 mRNA CTD PMID:15911693 , PMID:27939613 obeticholic acid multiple interactions ISO RGD:2482 15036816 Obeticholic acid inhibits the reaction [ethanol increases expression of Cyp7a1 protein in liver] RGD okadaic acid multiple interactions EXP 6480464 Okadaic Acid promotes the reaction [Calcitriol results in decreased expression of CYP7A1 mRNA], Okadaic Acid promotes the reaction [lithocholic acid acetate results in decreased expression of CYP7A1 mRNA] CTD PMID:20371703 oleanolic acid decreases expression ISO RGD:10458 6480464 Oleanolic Acid results in decreased expression of CYP7A1 mRNA, Oleanolic Acid results in decreased expression of CYP7A1 protein CTD PMID:23948738 orphenadrine affects expression ISO RGD:2482 6480464 Orphenadrine affects the expression of CYP7A1 mRNA CTD PMID:23665939 oxybenzone increases expression ISO RGD:2482 6480464 oxybenzone results in increased expression of CYP7A1 mRNA CTD PMID:30316929 p-chloromercuribenzoic acid decreases activity ISO RGD:2482 6480464 p-Chloromercuribenzoic Acid results in decreased activity of CYP7A1 protein CTD PMID:1175606 paclitaxel decreases expression ISO RGD:2482 6480464 Paclitaxel results in decreased expression of CYP7A1 mRNA CTD PMID:15585946 paracetamol affects expression ISO RGD:10458 6480464 Acetaminophen affects the expression of CYP7A1 mRNA CTD PMID:15030884 , PMID:17562736 paracetamol decreases expression ISO RGD:10458 6480464 Acetaminophen results in decreased expression of CYP7A1 mRNA CTD PMID:18544908 paracetamol decreases expression ISO RGD:2482 6480464 Acetaminophen results in decreased expression of CYP7A1 mRNA CTD PMID:15120968 , PMID:17202762 pentachlorophenol increases expression ISO RGD:10458 6480464 Pentachlorophenol results in increased expression of CYP7A1 mRNA CTD PMID:23892564 perflubutane decreases expression ISO RGD:10458 6480464 perfluorobutane results in decreased expression of CYP7A1 mRNA CTD PMID:23567314 perfluorobutanesulfonic acid increases expression ISO RGD:10458 6480464 perfluorobutanesulfonic acid results in increased expression of CYP7A1 mRNA CTD PMID:32534104 perfluorobutyric acid increases expression ISO RGD:2482 6480464 perfluorobutyric acid analog results in increased expression of CYP7A1 mRNA CTD PMID:21878386 perfluorodecanoic acid decreases expression EXP 6480464 perfluorodecanoic acid results in decreased expression of CYP7A1 mRNA CTD PMID:23567314 perfluorodecanoic acid decreases expression ISO RGD:10458 6480464 perfluorodecanoic acid results in decreased expression of CYP7A1 mRNA CTD PMID:27344344 perfluorodecanoic acid multiple interactions ISO RGD:10458 6480464 PPARA protein affects the reaction [perfluorodecanoic acid results in decreased expression of CYP7A1 mRNA] CTD PMID:27344344 perfluorodecanoic acid increases expression ISO RGD:10458 6480464 perfluorodecanoic acid results in increased expression of CYP7A1 mRNA CTD PMID:23567314 perfluorododecanoic acid decreases expression EXP 6480464 perfluorododecanoic acid results in decreased expression of CYP7A1 mRNA CTD PMID:23567314 perfluorododecanoic acid decreases expression ISO RGD:10458 6480464 perfluorododecanoic acid results in decreased expression of CYP7A1 mRNA CTD PMID:23567314 perfluorohexanesulfonic acid decreases expression ISO RGD:10458 6480464 perfluorohexanesulfonic acid results in decreased expression of CYP7A1 mRNA CTD PMID:21705711 , PMID:23567314 perfluorohexanesulfonic acid decreases expression EXP 6480464 perfluorohexanesulfonic acid results in decreased expression of CYP7A1 mRNA CTD PMID:23567314 perfluorohexanoic acid decreases expression EXP 6480464 perfluorohexanoic acid results in decreased expression of CYP7A1 mRNA CTD PMID:23567314 perfluorononanoic acid decreases expression ISO RGD:10458 6480464 perfluorononanoic acid results in decreased expression of CYP7A1 mRNA CTD PMID:29112762 perfluorononanoic acid decreases expression EXP 6480464 perfluoro-n-nonanoic acid results in decreased expression of CYP7A1 mRNA, perfluorononanoic acid results in decreased expression of CYP7A1 mRNA CTD PMID:23567314 , PMID:32588087 perfluorooctane-1-sulfonic acid decreases expression ISO RGD:2482 6480464 perfluorooctane sulfonic acid results in decreased expression of CYP7A1 mRNA CTD PMID:16221955 more ... perfluorooctane-1-sulfonic acid decreases expression EXP 6480464 perfluorooctane sulfonic acid results in decreased expression of CYP7A1 mRNA, perfluorooctane sulfonic acid results in decreased expression of CYP7A1 protein CTD PMID:27153767 , PMID:32253466 perfluorooctane-1-sulfonic acid decreases expression ISO RGD:10458 6480464 perfluorooctane sulfonic acid results in decreased expression of CYP7A1 mRNA CTD PMID:19429403 more ... perfluorooctane-1-sulfonic acid multiple interactions ISO RGD:10458 6480464 PPARA protein promotes the reaction [perfluorooctane sulfonic acid results in decreased expression of CYP7A1 mRNA] CTD PMID:20936131 perfluorooctanoic acid decreases expression ISO RGD:10458 6480464 perfluorooctanoic acid results in decreased expression of CYP7A1 mRNA CTD PMID:17681415 more ... perfluorooctanoic acid decreases expression EXP 6480464 perfluorooctanoic acid results in decreased expression of CYP7A1 mRNA, perfluorooctanoic acid results in decreased expression of CYP7A1 protein CTD PMID:23567314 more ... perfluorooctanoic acid multiple interactions ISO RGD:10458 6480464 PPARA protein promotes the reaction [perfluorooctanoic acid results in decreased expression of CYP7A1 mRNA] CTD PMID:20936131 perfluoroundecanoic acid decreases expression EXP 6480464 perfluoro-n-undecanoic acid results in decreased expression of CYP7A1 mRNA CTD PMID:23567314 phenformin decreases expression ISO RGD:2482 6480464 Phenformin results in decreased expression of CYP7A1 mRNA CTD PMID:31324951 phenobarbital affects expression EXP 6480464 Phenobarbital affects the expression of CYP7A1 mRNA CTD PMID:15629111 phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of CYP7A1 mRNA CTD PMID:22258563 phenobarbital multiple interactions ISO RGD:10458 6480464 [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of CYP7A1 mRNA CTD PMID:24535843 phenobarbital decreases expression ISO RGD:2482 6480464 Phenobarbital results in decreased expression of CYP7A1 mRNA CTD PMID:19162173 phenobarbital decreases expression ISO RGD:10458 6480464 Phenobarbital results in decreased expression of CYP7A1 mRNA CTD PMID:15629111 phenobarbital increases expression ISO RGD:10458 6480464 Phenobarbital results in increased expression of CYP7A1 mRNA CTD PMID:19270015 phenytoin multiple interactions ISO RGD:10458 6480464 [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP7A1 mRNA CTD PMID:21224054 phorbol 13-acetate 12-myristate multiple interactions EXP 6480464 [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CYP7A1 mRNA CTD PMID:16979875 phosphatidylcholine increases activity ISO RGD:2482 6480464 Phosphatidylcholines results in increased activity of CYP7A1 protein CTD PMID:12559476 pioglitazone multiple interactions ISO RGD:10458 6480464 pioglitazone promotes the reaction [U 0126 results in increased expression of CYP7A1 mRNA], U 0126 promotes the reaction [pioglitazone results in increased expression of CYP7A1 mRNA] CTD PMID:22593575 pioglitazone increases expression ISO RGD:10458 6480464 pioglitazone results in increased expression of CYP7A1 mRNA CTD PMID:22593575 pirinixic acid multiple interactions ISO RGD:10458 6480464 PPARA protein affects the reaction [pirinixic acid results in decreased expression of CYP7A1 mRNA], PPARA protein promotes the reaction [pirinixic acid results in decreased expression of CYP7A1 mRNA] CTD PMID:15777286 more ... pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of CYP7A1 mRNA CTD PMID:31676336 pirinixic acid decreases expression ISO RGD:10458 6480464 pirinixic acid results in decreased expression of CYP7A1 mRNA CTD PMID:15777286 more ... pirinixic acid increases expression ISO RGD:10458 6480464 pirinixic acid results in increased expression of CYP7A1 mRNA CTD PMID:20936131 pregnenolone decreases activity ISO RGD:2482 6480464 Pregnenolone results in decreased activity of CYP7A1 protein CTD PMID:1175606 pregnenolone 16alpha-carbonitrile decreases expression ISO RGD:2482 6480464 Pregnenolone Carbonitrile results in decreased expression of CYP7A1 mRNA CTD PMID:19162173 pregnenolone 16alpha-carbonitrile decreases expression ISO RGD:10458 6480464 Pregnenolone Carbonitrile results in decreased expression of CYP7A1 mRNA CTD PMID:15629111 more ... pregnenolone 16alpha-carbonitrile multiple interactions ISO RGD:10458 6480464 Pregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in decreased expression of CYP7A1 mRNA] CTD PMID:20359477 prochloraz decreases expression EXP 6480464 prochloraz results in decreased expression of CYP7A1 mRNA CTD PMID:32194361 propiconazole increases expression ISO RGD:10458 6480464 propiconazole results in increased expression of CYP7A1 mRNA CTD PMID:21278054 propiconazole decreases expression EXP 6480464 propiconazole results in decreased expression of CYP7A1 mRNA CTD PMID:32194361 psoralen decreases expression ISO RGD:2482 6480464 Ficusin results in decreased expression of CYP7A1 mRNA, Ficusin results in decreased expression of CYP7A1 protein CTD PMID:30597224 puerarin multiple interactions ISO RGD:2482 6480464 puerarin affects the reaction [Lead affects the expression of CYP7A1] CTD PMID:22001170 PX-866 multiple interactions ISO RGD:10458 6480464 [PX-866 co-treated with SORT1 protein] results in decreased expression of CYP7A1 mRNA CTD PMID:25805502 pyrazinecarboxamide increases expression ISO RGD:2482 6480464 Pyrazinamide results in increased expression of CYP7A1 mRNA, Pyrazinamide results in increased expression of CYP7A1 protein CTD PMID:27255380 pyrrolidines decreases expression ISO RGD:2482 6480464 Pyrrolidines analog results in decreased expression of CYP7A1 mRNA CTD PMID:26365562 resveratrol multiple interactions ISO RGD:10458 6480464 [Resveratrol results in increased activity of NR1H3 protein] which results in increased expression of CYP7A1 mRNA more ... CTD PMID:22607622 , PMID:31298478 resveratrol increases expression ISO RGD:10458 6480464 resveratrol results in increased expression of CYP7A1 mRNA CTD PMID:22607622 , PMID:23146569 resveratrol multiple interactions ISO RGD:2482 6480464 resveratrol inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of CYP7A1 mRNA], resveratrol inhibits the reaction [1-Naphthylisothiocyanate results in decreased expression of CYP7A1 protein] CTD PMID:25418378 rifampicin multiple interactions ISO RGD:10458 6480464 [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of CYP7A1 mRNA CTD PMID:21224054 rifampicin multiple interactions EXP 6480464 NR1I2 protein promotes the reaction [Rifampin results in decreased expression of CYP7A1 mRNA] CTD PMID:21127053 rifampicin decreases expression EXP 6480464 Rifampin results in decreased expression of CYP7A1 mRNA CTD PMID:15629111 more ... rifaximin multiple interactions EXP 6480464 [NR1I2 results in increased susceptibility to rifaximin] which results in increased expression of CYP7A1 protein CTD PMID:22790967 ritonavir decreases expression EXP 6480464 Ritonavir results in decreased expression of CYP7A1 mRNA CTD PMID:26626330 ritonavir decreases expression ISO RGD:2482 6480464 Ritonavir results in decreased expression of CYP7A1 mRNA CTD PMID:17719200 rotenone affects expression ISO RGD:2482 6480464 Rotenone affects the expression of CYP7A1 mRNA CTD PMID:28374803 Salidroside multiple interactions ISO RGD:10458 6480464 rhodioloside inhibits the reaction [furan results in decreased expression of CYP7A1 mRNA] CTD PMID:32251705 selenium atom multiple interactions ISO RGD:2482 6480464 [Magnesium co-treated with Selenium co-treated with Dietary Fats] results in increased expression of CYP7A1 mRNA CTD PMID:30031400 senecionine decreases expression ISO RGD:2482 6480464 senecionine results in decreased expression of CYP7A1 mRNA CTD PMID:24641316 senecionine decreases expression ISO RGD:10458 6480464 senecionine results in decreased expression of CYP7A1 mRNA CTD PMID:31606820 senecionine decreases expression EXP 6480464 senecionine results in decreased expression of CYP7A1 mRNA CTD PMID:26100227 Senkirkine decreases expression EXP 6480464 senkirkine results in decreased expression of CYP7A1 mRNA CTD PMID:26100227 sevoflurane affects expression ISO RGD:2482 6480464 sevoflurane affects the expression of CYP7A1 mRNA CTD PMID:15967596 sodium arsenite decreases expression ISO RGD:10458 6480464 sodium arsenite results in decreased expression of CYP7A1 mRNA CTD PMID:31532247 sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of CYP7A1 mRNA CTD PMID:29301061 sodium cholate multiple interactions ISO RGD:10458 6480464 [Sodium Cholate co-treated with Dietary Fats] results in decreased expression of CYP7A1 mRNA CTD PMID:23665937 sodium dichromate increases expression ISO RGD:2482 6480464 sodium bichromate results in increased expression of CYP7A1 mRNA CTD PMID:12325037 soybean oil increases activity ISO RGD:2482 6480464 Soybean Oil results in increased activity of CYP7A1 protein CTD PMID:12559476 spironolactone decreases activity ISO RGD:2482 6480464 Spironolactone results in decreased activity of CYP7A1 protein CTD PMID:15652244 streptozocin increases expression ISO RGD:2482 6480464 Streptozocin results in increased expression of CYP7A1 mRNA CTD PMID:10393316 streptozocin multiple interactions ISO RGD:10458 6480464 [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 mRNA, [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 protein CTD PMID:29382564 streptozocin multiple interactions ISO RGD:2482 6480464 [Dietary Fats co-treated with Streptozocin] results in decreased expression of CYP7A1 mRNA more ... CTD PMID:31100278 tamoxifen decreases expression ISO RGD:2482 6480464 Tamoxifen results in decreased expression of CYP7A1 mRNA CTD PMID:19224547 tamoxifen affects expression ISO RGD:10458 6480464 Tamoxifen affects the expression of CYP7A1 mRNA CTD PMID:20937368 taurocholic acid multiple interactions ISO RGD:10458 6480464 FGFR4 protein affects the reaction [Taurocholic Acid results in decreased expression of CYP7A1 mRNA], NR1H4 protein affects the reaction [Taurocholic Acid results in decreased expression of CYP7A1 mRNA] CTD PMID:16284190 taurocholic acid decreases expression ISO RGD:2482 6480464 Taurocholic Acid results in decreased expression of CYP7A1 mRNA CTD PMID:7832767 taurocholic acid decreases expression ISO RGD:10458 6480464 Taurocholic Acid results in decreased expression of CYP7A1 mRNA CTD PMID:16284190 tebuconazole decreases expression EXP 6480464 tebuconazole results in decreased expression of CYP7A1 mRNA CTD PMID:30458266 , PMID:32194361 Tesaglitazar decreases expression ISO RGD:2482 6480464 tesaglitazar results in decreased expression of CYP7A1 mRNA CTD PMID:21515302 testosterone decreases expression ISO RGD:10458 6480464 Testosterone results in decreased expression of CYP7A1 mRNA CTD PMID:21669218 tetrachloromethane decreases expression ISO RGD:2482 6480464 Carbon Tetrachloride results in decreased expression of CYP7A1 mRNA CTD PMID:19224547 , PMID:31150632 tetrachloromethane increases expression ISO RGD:2482 6480464 Carbon Tetrachloride results in increased expression of CYP7A1 mRNA CTD PMID:30723492 tetrachloromethane increases expression ISO RGD:10458 6480464 Carbon Tetrachloride results in increased expression of CYP7A1 mRNA CTD PMID:29987408 tetrachloromethane multiple interactions ISO RGD:2482 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of CYP7A1 mRNA] CTD PMID:31150632 tetrachloromethane decreases expression ISO RGD:10458 6480464 Carbon Tetrachloride results in decreased expression of CYP7A1 mRNA CTD PMID:27339419 , PMID:31919559 tetracycline increases expression ISO RGD:10458 6480464 Tetracycline results in increased expression of CYP7A1 mRNA CTD PMID:16917069 tetracycline decreases expression ISO RGD:2482 6480464 Tetracycline results in decreased expression of CYP7A1 mRNA CTD PMID:19224547 thiacloprid decreases expression EXP 6480464 thiacloprid results in decreased expression of CYP7A1 protein CTD PMID:32194361 thiamethoxam decreases expression EXP 6480464 Thiamethoxam results in decreased expression of CYP7A1 protein CTD PMID:32194361 thioacetamide increases expression ISO RGD:2482 6480464 Thioacetamide results in increased expression of CYP7A1 mRNA CTD PMID:26222700 thiram decreases expression EXP 6480464 Thiram results in decreased expression of CYP7A1 mRNA CTD PMID:32194361 titanium dioxide multiple interactions ISO RGD:10458 6480464 Resveratrol promotes the reaction [titanium dioxide results in decreased expression of CYP7A1 mRNA] CTD PMID:31298478 titanium dioxide decreases expression ISO RGD:10458 6480464 titanium dioxide results in decreased expression of CYP7A1 mRNA CTD PMID:31298478 toluene affects expression ISO RGD:2482 6480464 Toluene affects the expression of CYP7A1 mRNA CTD PMID:18653662 tributylstannane increases expression ISO RGD:10458 6480464 tributyltin results in increased expression of CYP7A1 mRNA CTD PMID:31939706 Tributyltin oxide decreases expression ISO RGD:10458 6480464 bistri-n-butyltinoxide results in decreased expression of CYP7A1 mRNA CTD PMID:18958704 trichloroethene increases expression ISO RGD:10458 6480464 Trichloroethylene results in increased expression of CYP7A1 mRNA CTD PMID:19254012 trichloroethene increases methylation ISO RGD:2482 6480464 Trichloroethylene results in increased methylation of CYP7A1 gene CTD PMID:27618143 trichloroethene decreases expression ISO RGD:10458 6480464 Trichloroethylene results in decreased expression of CYP7A1 mRNA CTD PMID:25549359 triphenyl phosphate increases expression ISO RGD:2482 6480464 triphenyl phosphate results in increased expression of CYP7A1 mRNA CTD PMID:30589522 tris(2-butoxyethyl) phosphate decreases expression EXP 6480464 tris2-butoxyethyl phosphate results in decreased expression of CYP7A1 mRNA CTD PMID:29024780 troglitazone decreases expression EXP 6480464 troglitazone results in decreased expression of CYP7A1 mRNA CTD PMID:19631733 troglitazone increases expression ISO RGD:2482 6480464 troglitazone results in increased expression of CYP7A1 mRNA CTD PMID:21515302 trovafloxacin multiple interactions ISO RGD:10458 6480464 [trovafloxacin co-treated with lipopolysaccharide, E coli O55-B5] results in decreased expression of CYP7A1 mRNA CTD PMID:18930950 urethane decreases expression EXP 6480464 Urethane results in decreased expression of CYP7A1 mRNA CTD PMID:28818685 ursodeoxycholic acid multiple interactions ISO RGD:2482 6480464 [Tretinoin co-treated with Ursodeoxycholic Acid] results in decreased expression of CYP7A1 mRNA, Ursodeoxycholic Acid inhibits the reaction [Ethinyl Estradiol results in decreased expression of CYP7A1 mRNA] CTD PMID:16487557 , PMID:21274875 ursodeoxycholic acid decreases expression ISO RGD:10458 6480464 Ursodeoxycholic Acid results in decreased expression of CYP7A1 mRNA CTD PMID:20671298 , PMID:25582706 ursodeoxycholic acid decreases expression EXP 6480464 Ursodeoxycholic Acid results in decreased expression of CYP7A1 mRNA CTD PMID:14684751 , PMID:21274875 ursodeoxycholic acid increases expression ISO RGD:2482 6480464 Ursodeoxycholic Acid results in increased expression of CYP7A1 mRNA CTD PMID:16764892 ursodeoxycholic acid multiple interactions EXP 6480464 Tretinoin promotes the reaction [Ursodeoxycholic Acid results in decreased expression of CYP7A1 mRNA], Ursodeoxycholic Acid promotes the reaction [Tretinoin results in decreased expression of CYP7A1 mRNA] CTD PMID:21274875 usnic acid multiple interactions EXP 6480464 [usnic acid co-treated with Lipopolysaccharides] results in decreased expression of CYP7A1 mRNA CTD PMID:22777745 valdecoxib decreases expression ISO RGD:2482 6480464 valdecoxib results in decreased expression of CYP7A1 mRNA CTD PMID:24136188 valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of CYP7A1 mRNA CTD PMID:29154799 , PMID:29501571 vancomycin multiple interactions ISO RGD:10458 6480464 [Vancomycin co-treated with Imipenem] results in decreased expression of CYP7A1 mRNA CTD PMID:24657338 Yangonin multiple interactions ISO RGD:10458 6480464 NR1H4 promotes the reaction [yangonin promotes the reaction [1-Naphthylisothiocyanate results in decreased expression of CYP7A1 mRNA]] more ... CTD PMID:29660435 Yangonin decreases expression ISO RGD:10458 6480464 yangonin results in decreased expression of CYP7A1 mRNA CTD PMID:29660435 zinc atom multiple interactions EXP 6480464 [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CYP7A1 mRNA CTD PMID:16979875 zinc atom decreases activity ISO RGD:2482 6480464 Zinc results in decreased activity of CYP7A1 protein CTD PMID:1175606 zinc atom increases expression EXP 6480464 Zinc deficiency results in increased expression of CYP7A1 mRNA CTD PMID:18356318 zinc pyrithione increases expression EXP 6480464 pyrithione zinc results in increased expression of CYP7A1 mRNA CTD PMID:21424779 zinc(0) multiple interactions EXP 6480464 [Zinc co-treated with Tetradecanoylphorbol Acetate] affects the expression of CYP7A1 mRNA CTD PMID:16979875 zinc(0) increases expression EXP 6480464 Zinc deficiency results in increased expression of CYP7A1 mRNA CTD PMID:18356318 zinc(0) decreases activity ISO RGD:2482 6480464 Zinc results in decreased activity of CYP7A1 protein CTD PMID:1175606
