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Gene: METAP2 (methionyl aminopeptidase 2) Homo sapiens
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Symbol: METAP2
Name: methionyl aminopeptidase 2
Description: Exhibits aminopeptidase activity and metalloexopeptidase activity. Involved in N-terminal protein amino acid modification; peptidyl-methionine modification; and protein processing. Localizes to the cytosol and plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: eIF-2-associated p67 homolog; initiation factor 2-associated 67 kDa glycoprotein; MAP 2; MAP2; metAP 2; methionine aminopeptidase 2; MNPEP; p67; p67eIF2; peptidase M 2; testicular tissue protein Li 17
Orthologs:
Mus musculus (house mouse) : Metap2 (methionine aminopeptidase 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Metap2 (methionyl aminopeptidase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Metap2 (methionyl aminopeptidase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : METAP2 (methionyl aminopeptidase 2)
Canis lupus familiaris (dog) : METAP2 (methionyl aminopeptidase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Metap2 (methionyl aminopeptidase 2)
Sus scrofa (pig) : METAP2 (methionyl aminopeptidase 2)
more info ...
Related Pseudogenes: METAP2P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381295,474,152 - 95,515,839 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371295,867,822 - 95,909,615 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361294,391,953 - 94,433,746 (+)NCBINCBI36hg18NCBI36
Build 341294,370,389 - 94,410,587NCBI
Celera1295,538,718 - 95,580,736 (+)NCBI
Cytogenetic Map12q22NCBI
HuRef1292,936,350 - 92,977,989 (+)NCBIHuRef
CHM1_11295,833,252 - 95,875,049 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on METAP2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732103
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.