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Gene: SMG7 (SMG7 nonsense mediated mRNA decay factor) Homo sapiens
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Symbol: SMG7
Name: SMG7 nonsense mediated mRNA decay factor
Description: Exhibits protein phosphatase 2A binding activity and telomeric DNA binding activity. Predicted to be involved in regulation of telomere maintenance via telomerase and telomere maintenance via telomerase. Localizes to cytosol; intermediate filament cytoskeleton; and nucleus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: breast cancer-associated antigen SGA-56M; C1orf16; EST1 telomerase component homolog C; EST1-like protein C; EST1C; ever shorter telomeres 1C; FLJ23717; KIAA0250; SGA56M; SMG-7; smg-7 homolog, nonsense mediated mRNA decay factor; SMG7, nonsense mediated mRNA decay factor
Orthologs:
Mus musculus (house mouse) : Smg7 (Smg-7 homolog, nonsense mediated mRNA decay factor (C. elegans))  MGI  Alliance
Rattus norvegicus (Norway rat) : Smg7 (SMG7 nonsense mediated mRNA decay factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Smg7 (SMG7 nonsense mediated mRNA decay factor)
Pan paniscus (bonobo/pygmy chimpanzee) : SMG7 (SMG7 nonsense mediated mRNA decay factor)
Canis lupus familiaris (dog) : SMG7 (SMG7 nonsense mediated mRNA decay factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Smg7 (SMG7 nonsense mediated mRNA decay factor)
Sus scrofa (pig) : SMG7 (SMG7 nonsense mediated mRNA decay factor)
Chlorocebus sabaeus (African green monkey) : SMG7 (SMG7 nonsense mediated mRNA decay factor)
Heterocephalus glaber (naked mole-rat) : Smg7 (SMG7 nonsense mediated mRNA decay factor)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1183,472,216 - 183,598,246 (+)EnsemblGRCh38hg38GRCh38
GRCh381183,471,993 - 183,554,193 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371183,441,506 - 183,523,328 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361181,708,257 - 181,789,949 (+)NCBINCBI36hg18NCBI36
Build 341180,173,290 - 180,254,982NCBI
Celera1156,552,563 - 156,634,375 (+)NCBI
Cytogenetic Map1q25.3NCBI
HuRef1154,677,519 - 154,759,191 (+)NCBIHuRef
CHM1_11184,864,494 - 184,946,346 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - uncurated

Genomics

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miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

External Database Links
Nomenclature History
 
More on SMG7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1321852
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.