SIRPA (signal regulatory protein alpha) - Rat Genome Database

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Gene: SIRPA (signal regulatory protein alpha) Homo sapiens
Analyze
Symbol: SIRPA
Name: signal regulatory protein alpha
RGD ID: 736759
HGNC Page HGNC:9662
Description: Enables cell-cell adhesion mediator activity and protein antigen binding activity. Involved in several processes, including cellular response to interleukin-12; positive regulation of reactive oxygen species metabolic process; and regulation of cytokine production. Located in cell surface and plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: BIT; brain-immunoglobulin-like molecule with tyrosine-based activation motifs; CD172 antigen-like family member A; CD172A; inhibitory receptor SHPS-1; macrophage fusion receptor; MFR; MYD-1; myd-1 antigen; P84; protein tyrosine phosphatase, non-receptor type substrate 1; PTPNS1; SHP substrate-1; SHPS-1; SHPS1; signal regulatory protein, alpha type 1; signal-regulatory protein alpha; SIRP; SIRP-ALPHA-1; SIRPalpha; SIRPalpha2; tyrosine phosphatase SHP substrate 1; tyrosine-protein phosphatase non-receptor type substrate 1
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: SIRPAP1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38201,894,167 - 1,940,592 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl201,894,167 - 1,940,592 (+)EnsemblGRCh38hg38GRCh38
GRCh37201,874,813 - 1,921,238 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36201,822,813 - 1,868,540 (+)NCBINCBI36Build 36hg18NCBI36
Build 34201,823,424 - 1,868,535NCBI
Celera201,938,791 - 1,984,521 (+)NCBICelera
Cytogenetic Map20p13NCBI
HuRef201,824,406 - 1,870,408 (+)NCBIHuRef
CHM1_1201,875,015 - 1,920,758 (+)NCBICHM1_1
T2T-CHM13v2.0201,924,358 - 1,970,769 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
3-chloropropane-1,2-diol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
4-vinylcyclohexene dioxide  (ISO)
aflatoxin B1  (EXP)
Aflatoxin B2 alpha  (EXP)
all-trans-retinoic acid  (EXP)
ammonium chloride  (ISO)
antirheumatic drug  (EXP)
aristolochic acid A  (EXP)
arsenite(3-)  (EXP)
arsenous acid  (EXP)
atrazine  (EXP)
benzene  (EXP)
benzo[a]pyrene  (EXP,ISO)
beta-lapachone  (EXP)
bisphenol A  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (EXP)
carbon nanotube  (ISO)
CGP 52608  (EXP)
choline  (ISO)
copper(II) sulfate  (EXP)
cycloheximide  (EXP)
cyproconazole  (ISO)
D-gluconic acid  (ISO)
deoxycholic acid  (ISO)
diarsenic trioxide  (EXP)
Dibutyl phosphate  (EXP)
dibutyl phthalate  (ISO)
dichlorine  (ISO)
elemental selenium  (EXP)
endosulfan  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
fipronil  (ISO)
folic acid  (ISO)
fonofos  (EXP)
gentamycin  (ISO)
glafenine  (ISO)
isotretinoin  (EXP)
L-methionine  (ISO)
leflunomide  (EXP)
lipopolysaccharide  (EXP)
LY294002  (EXP)
menadione  (EXP)
methotrexate  (EXP)
methoxychlor  (ISO)
Muraglitazar  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosomorpholine  (ISO)
nickel atom  (EXP)
nickel sulfate  (EXP)
nitrofen  (ISO)
NSC 23766  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
parathion  (EXP)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
pirinixic acid  (ISO)
potassium chromate  (EXP)
progesterone  (EXP)
propiconazole  (ISO)
selenium atom  (EXP)
silicon dioxide  (ISO)
sodium arsenite  (EXP,ISO)
sodium fluoride  (ISO)
terbufos  (EXP)
Tesaglitazar  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (ISO)
thimerosal  (EXP)
thioacetamide  (ISO)
titanium dioxide  (ISO)
trichostatin A  (EXP)
triclosan  (EXP)
triphenyl phosphate  (EXP)
triptonide  (ISO)
tris(2-butoxyethyl) phosphate  (EXP)
troglitazone  (ISO)
tungsten  (ISO)
valproic acid  (EXP)
vorinostat  (EXP)
wortmannin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
actin filament organization  (ISO)
cell adhesion  (TAS)
cell migration  (ISO,ISS)
cell motility  (ISO)
cell-cell adhesion  (IEA)
cell-matrix adhesion  (ISO)
cellular response to hydrogen peroxide  (ISS)
cellular response to interleukin-1  (ISS)
cellular response to interleukin-12  (IMP)
cellular response to type II interferon  (ISS)
cytoskeleton organization  (ISO)
granulocyte migration  (ISO)
hematopoietic progenitor cell differentiation  (ISO)
heterotypic cell-cell adhesion  (IEA)
monocyte extravasation  (ISS)
negative regulation of canonical NF-kappaB signal transduction  (ISS)
negative regulation of chemokine (C-C motif) ligand 5 production  (ISS)
negative regulation of cytokine production involved in inflammatory response  (ISS)
negative regulation of ERK1 and ERK2 cascade  (ISS)
negative regulation of inflammatory response  (IMP)
negative regulation of interferon-beta production  (ISS)
negative regulation of interleukin-6 production  (ISS)
negative regulation of JNK cascade  (ISS)
negative regulation of lipopolysaccharide-mediated signaling pathway  (ISS)
negative regulation of macrophage inflammatory protein 1 alpha production  (ISS)
negative regulation of nitric oxide biosynthetic process  (ISS)
negative regulation of phagocytosis  (ISS)
negative regulation of tumor necrosis factor production  (ISS)
phagocytosis, engulfment  (ISO)
phagocytosis, recognition  (ISO)
positive regulation of phagocytosis  (IBA,ISO)
positive regulation of reactive oxygen species metabolic process  (IDA)
positive regulation of T cell activation  (IBA)
regulation of gene expression  (IMP)
regulation of interleukin-1 beta production  (ISS)
regulation of interleukin-6 production  (ISS)
regulation of nitric oxide biosynthetic process  (ISS)
regulation of tumor necrosis factor production  (IGI,ISS)
regulation of type II interferon production  (IMP)

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8525433   PMID:8810330   PMID:8943344   PMID:9062191   PMID:9070220   PMID:9271230   PMID:9485180   PMID:9632768   PMID:9712903   PMID:9872987   PMID:10098842   PMID:10469599  
PMID:10572074   PMID:10585853   PMID:10660565   PMID:10660620   PMID:10842184   PMID:10962556   PMID:11509594   PMID:11780052   PMID:11792697   PMID:11907074   PMID:12477932   PMID:12483539  
PMID:12805067   PMID:14662855   PMID:14729615   PMID:15359629   PMID:15374953   PMID:15489334   PMID:15842360   PMID:15888547   PMID:16189514   PMID:16291597   PMID:16335952   PMID:16339511  
PMID:16344560   PMID:16691243   PMID:16697668   PMID:16825188   PMID:17070842   PMID:17098740   PMID:17142753   PMID:17178844   PMID:17360380   PMID:17500595   PMID:17632076   PMID:17954568  
PMID:17999719   PMID:18051954   PMID:18647419   PMID:18820737   PMID:18855618   PMID:18954403   PMID:19056867   PMID:19165527   PMID:19299420   PMID:19628875   PMID:19748659   PMID:19820697  
PMID:19874234   PMID:20207740   PMID:20299253   PMID:20473329   PMID:20643654   PMID:20705613   PMID:20826546   PMID:20826801   PMID:21169408   PMID:21223598   PMID:21225905   PMID:21369691  
PMID:21706016   PMID:21788504   PMID:21788509   PMID:21799000   PMID:21873635   PMID:22139419   PMID:22409853   PMID:22451913   PMID:22490440   PMID:22511785   PMID:22738830   PMID:22747997  
PMID:22815949   PMID:23271705   PMID:23314616   PMID:23320069   PMID:23504854   PMID:23669395   PMID:24026300   PMID:24101669   PMID:24124411   PMID:24143245   PMID:24162948   PMID:24511121  
PMID:24516072   PMID:24550402   PMID:24968096   PMID:25416956   PMID:25468996   PMID:25795378   PMID:25837251   PMID:26085683   PMID:26116271   PMID:26186194   PMID:26492885   PMID:26534964  
PMID:26573233   PMID:27728760   PMID:27793032   PMID:27856600   PMID:27900675   PMID:28514442   PMID:28669759   PMID:29084248   PMID:29158380   PMID:29180619   PMID:30194290   PMID:30639242  
PMID:30833751   PMID:30863997   PMID:30888336   PMID:30910815   PMID:31089204   PMID:31507080   PMID:31611550   PMID:32196807   PMID:32240171   PMID:32296183   PMID:32393512   PMID:32433947  
PMID:33799989   PMID:33961781   PMID:34009732   PMID:34079125   PMID:34180101   PMID:34349018   PMID:34512146   PMID:34667145   PMID:34917090   PMID:34940829   PMID:35337019   PMID:35737088  
PMID:35795660   PMID:36202053   PMID:36215168   PMID:36641515   PMID:36791324   PMID:37660478   PMID:37844448   PMID:38117590   PMID:38245585   PMID:38279488   PMID:38334954   PMID:38758648  


Genomics

Comparative Map Data
SIRPA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38201,894,167 - 1,940,592 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl201,894,167 - 1,940,592 (+)EnsemblGRCh38hg38GRCh38
GRCh37201,874,813 - 1,921,238 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36201,822,813 - 1,868,540 (+)NCBINCBI36Build 36hg18NCBI36
Build 34201,823,424 - 1,868,535NCBI
Celera201,938,791 - 1,984,521 (+)NCBICelera
Cytogenetic Map20p13NCBI
HuRef201,824,406 - 1,870,408 (+)NCBIHuRef
CHM1_1201,875,015 - 1,920,758 (+)NCBICHM1_1
T2T-CHM13v2.0201,924,358 - 1,970,769 (+)NCBIT2T-CHM13v2.0
Sirpa
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392129,432,962 - 129,474,148 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2129,434,755 - 129,474,148 (+)EnsemblGRCm39 Ensembl
GRCm382129,591,042 - 129,632,228 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2129,592,835 - 129,632,228 (+)EnsemblGRCm38mm10GRCm38
MGSCv372129,418,575 - 129,457,964 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362129,284,759 - 129,322,373 (+)NCBIMGSCv36mm8
Celera2130,820,643 - 130,860,425 (+)NCBICelera
Cytogenetic Map2F1NCBI
cM Map263.19NCBI
Sirpa
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83137,272,932 - 137,311,279 (+)NCBIGRCr8
mRatBN7.23116,819,730 - 116,858,099 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3116,819,726 - 116,858,098 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3120,717,512 - 120,755,285 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03129,313,130 - 129,350,902 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03126,973,615 - 127,011,386 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03122,113,735 - 122,152,478 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3122,114,108 - 122,152,477 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03127,864,145 - 127,902,598 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43117,210,116 - 117,247,840 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13117,115,688 - 117,153,412 (+)NCBI
Celera3115,635,887 - 115,673,609 (+)NCBICelera
Cytogenetic Map3q36NCBI
Sirpa
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495541513,030,752 - 13,072,735 (+)NCBIChiLan1.0ChiLan1.0
SIRPA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2212,887,607 - 2,933,424 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1202,884,271 - 2,930,254 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0202,006,994 - 2,052,894 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1201,773,271 - 1,818,106 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl201,773,271 - 1,818,106 (+)Ensemblpanpan1.1panPan2
SIRPA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12419,094,930 - 19,136,655 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2418,923,276 - 18,964,758 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02419,551,905 - 19,593,551 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.12419,108,428 - 19,149,479 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02419,218,798 - 19,260,377 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02419,547,368 - 19,588,981 (-)NCBIUU_Cfam_GSD_1.0
Sirpa
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640168,176,954 - 168,219,753 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493648516,608,317 - 16,654,552 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SIRPA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11733,566,270 - 33,611,375 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21737,961,460 - 37,968,581 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SIRPA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1254,590,151 - 54,636,381 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_0236660871,006,396 - 1,052,664 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sirpa
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247413,157,734 - 3,202,018 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in SIRPA
57 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 20p13-11.21(chr20:89939-25697564)x3 copy number gain See cases [RCV000051227] Chr20:89939..25697564 [GRCh38]
Chr20:70580..25678200 [GRCh37]
Chr20:18580..25626200 [NCBI36]
Chr20:20p13-11.21		 pathogenic
GRCh38/hg38 20p13-11.23(chr20:89939-19146279)x3 copy number gain See cases [RCV000051041] Chr20:89939..19146279 [GRCh38]
Chr20:70580..19126923 [GRCh37]
Chr20:18580..19074923 [NCBI36]
Chr20:20p13-11.23		 pathogenic
GRCh38/hg38 20p13(chr20:89939-1939218)x1 copy number loss See cases [RCV000052735] Chr20:89939..1939218 [GRCh38]
Chr20:70580..1919864 [GRCh37]
Chr20:18580..1867864 [NCBI36]
Chr20:20p13		 pathogenic
GRCh38/hg38 20p13(chr20:121781-2290194)x1 copy number loss See cases [RCV000052738] Chr20:121781..2290194 [GRCh38]
Chr20:102422..2270840 [GRCh37]
Chr20:50422..2218840 [NCBI36]
Chr20:20p13		 pathogenic
GRCh38/hg38 20p13-11.23(chr20:89939-19071495)x3 copy number gain See cases [RCV000052995] Chr20:89939..19071495 [GRCh38]
Chr20:70580..19052139 [GRCh37]
Chr20:18580..19000139 [NCBI36]
Chr20:20p13-11.23		 pathogenic
GRCh38/hg38 20p13-11.22(chr20:89939-21787252)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052996]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052996]|See cases [RCV000052996] Chr20:89939..21787252 [GRCh38]
Chr20:70580..21767890 [GRCh37]
Chr20:18580..21715890 [NCBI36]
Chr20:20p13-11.22		 pathogenic
GRCh38/hg38 20p13-12.1(chr20:89939-14818511)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052997]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052997]|See cases [RCV000052997] Chr20:89939..14818511 [GRCh38]
Chr20:70580..14799157 [GRCh37]
Chr20:18580..14747157 [NCBI36]
Chr20:20p13-12.1		 pathogenic
GRCh37/hg19 20p13(chr20:71023-2129746)x1 copy number loss See cases [RCV000184090] Chr20:71023..2129746 [GRCh37]
Chr20:20p13		 pathogenic
GRCh38/hg38 20p13-q11.1(chr20:80106-30227427)x3 copy number gain See cases [RCV000133996] Chr20:80106..30227427 [GRCh38]
Chr20:60747..29462103 [GRCh37]
Chr20:8747..28075764 [NCBI36]
Chr20:20p13-q11.1		 pathogenic
GRCh38/hg38 20p13-q13.33(chr20:99557-64277321)x3 copy number gain See cases [RCV000135859] Chr20:99557..64277321 [GRCh38]
Chr20:80198..62908674 [GRCh37]
Chr20:28198..62379118 [NCBI36]
Chr20:20p13-q13.33		 pathogenic
GRCh38/hg38 20p13-12.1(chr20:80106-13029401)x3 copy number gain See cases [RCV000138677] Chr20:80106..13029401 [GRCh38]
Chr20:60747..13010049 [GRCh37]
Chr20:8747..12958049 [NCBI36]
Chr20:20p13-12.1		 pathogenic
GRCh38/hg38 20p13-12.3(chr20:80093-6386012)x3 copy number gain See cases [RCV000139597] Chr20:80093..6386012 [GRCh38]
Chr20:60734..6366659 [GRCh37]
Chr20:8734..6314659 [NCBI36]
Chr20:20p13-12.3		 pathogenic
GRCh38/hg38 20p13-12.3(chr20:84402-6159078)x3 copy number gain See cases [RCV000141348] Chr20:84402..6159078 [GRCh38]
Chr20:65043..6139725 [GRCh37]
Chr20:13043..6087725 [NCBI36]
Chr20:20p13-12.3		 pathogenic
GRCh38/hg38 20p13-11.1(chr20:80927-26324843)x3 copy number gain See cases [RCV000142017] Chr20:80927..26324843 [GRCh38]
Chr20:61568..26305479 [GRCh37]
Chr20:9568..26253479 [NCBI36]
Chr20:20p13-11.1		 pathogenic
GRCh38/hg38 20p13-12.3(chr20:80927-5447679)x3 copy number gain See cases [RCV000142285] Chr20:80927..5447679 [GRCh38]
Chr20:61568..5428325 [GRCh37]
Chr20:9568..5376325 [NCBI36]
Chr20:20p13-12.3		 uncertain significance
GRCh38/hg38 20p13-12.3(chr20:1269303-8626911)x3 copy number gain See cases [RCV000142917] Chr20:1269303..8626911 [GRCh38]
Chr20:1249947..8607558 [GRCh37]
Chr20:1197947..8555558 [NCBI36]
Chr20:20p13-12.3		 pathogenic
GRCh38/hg38 20p13-11.23(chr20:80928-18688031)x3 copy number gain See cases [RCV000143426] Chr20:80928..18688031 [GRCh38]
Chr20:61569..18668675 [GRCh37]
Chr20:9569..18616675 [NCBI36]
Chr20:20p13-11.23		 pathogenic
GRCh37/hg19 20p13-12.3(chr20:121521-5564937)x3 copy number gain See cases [RCV000239772] Chr20:121521..5564937 [GRCh37]
Chr20:20p13-12.3		 pathogenic
GRCh37/hg19 20p13-11.1(chr20:80198-26075841)x3 copy number gain See cases [RCV000239954] Chr20:80198..26075841 [GRCh37]
Chr20:20p13-11.1		 pathogenic
GRCh37/hg19 20p13(chr20:61568-4914872)x3 copy number gain See cases [RCV000446883] Chr20:61568..4914872 [GRCh37]
Chr20:20p13		 pathogenic
GRCh37/hg19 20p13(chr20:121521-2073612)x1 copy number loss See cases [RCV000446640] Chr20:121521..2073612 [GRCh37]
Chr20:20p13		 pathogenic
GRCh37/hg19 20p13(chr20:61568-4904599)x3 copy number gain See cases [RCV000448397] Chr20:61568..4904599 [GRCh37]
Chr20:20p13		 pathogenic
GRCh37/hg19 20p13-q11.21(chr20:80198-26208081)x3 copy number gain not provided [RCV000487461] Chr20:80198..26208081 [GRCh37]
Chr20:20p13-q11.21		 pathogenic
GRCh37/hg19 20p13-12.3(chr20:213423-5483406)x3 copy number gain See cases [RCV000510531] Chr20:213423..5483406 [GRCh37]
Chr20:20p13-12.3		 uncertain significance
GRCh37/hg19 20p13(chr20:61568-2824960)x3 copy number gain See cases [RCV000511991] Chr20:61568..2824960 [GRCh37]
Chr20:20p13		 uncertain significance
GRCh37/hg19 20p13-q13.33(chr20:61569-62915555)x3 copy number gain See cases [RCV000510832] Chr20:61569..62915555 [GRCh37]
Chr20:20p13-q13.33		 pathogenic
NM_001040023.2(SIRPA):c.658G>A (p.Glu220Lys) single nucleotide variant not specified [RCV004290309] Chr20:1921616 [GRCh38]
Chr20:1902262 [GRCh37]
Chr20:20p13		 uncertain significance
GRCh37/hg19 20p13-q13.33(chr20:61569-62915555) copy number gain See cases [RCV000512450] Chr20:61569..62915555 [GRCh37]
Chr20:20p13-q13.33		 pathogenic
GRCh37/hg19 20p13-12.2(chr20:61568-10486106)x3 copy number gain See cases [RCV000512556] Chr20:61568..10486106 [GRCh37]
Chr20:20p13-12.2		 likely pathogenic
GRCh37/hg19 20p13(chr20:61568-2010334)x1 copy number loss not provided [RCV000684132] Chr20:61568..2010334 [GRCh37]
Chr20:20p13		 likely pathogenic
GRCh37/hg19 20p13-q13.33(chr20:63244-62948788)x3 copy number gain not provided [RCV000741058] Chr20:63244..62948788 [GRCh37]
Chr20:20p13-q13.33		 pathogenic
GRCh37/hg19 20p13-q13.33(chr20:63244-62961294)x3 copy number gain not provided [RCV000741059] Chr20:63244..62961294 [GRCh37]
Chr20:20p13-q13.33		 pathogenic
GRCh37/hg19 20p13(chr20:1895079-1895490)x0 copy number loss not provided [RCV000741069] Chr20:1895079..1895490 [GRCh37]
Chr20:20p13		 benign
GRCh37/hg19 20p13-q13.33(chr20:63244-62912463)x3 copy number gain not provided [RCV000741057] Chr20:63244..62912463 [GRCh37]
Chr20:20p13-q13.33		 pathogenic
NM_001040023.2(SIRPA):c.1389G>A (p.Ala463=) single nucleotide variant not provided [RCV000923960] Chr20:1937442 [GRCh38]
Chr20:1918088 [GRCh37]
Chr20:20p13		 likely benign
NM_001040023.2(SIRPA):c.637G>A (p.Ala213Thr) single nucleotide variant not provided [RCV000882878] Chr20:1921595 [GRCh38]
Chr20:1902241 [GRCh37]
Chr20:20p13		 benign
NM_001040023.2(SIRPA):c.754+6A>G single nucleotide variant not provided [RCV000950287] Chr20:1921718 [GRCh38]
Chr20:1902364 [GRCh37]
Chr20:20p13		 benign
NM_001040023.2(SIRPA):c.1059G>A (p.Pro353=) single nucleotide variant not provided [RCV000894471] Chr20:1922617 [GRCh38]
Chr20:1903263 [GRCh37]
Chr20:20p13		 likely benign
GRCh37/hg19 20p13(chr20:61568-2269777)x1 copy number loss not provided [RCV001007065] Chr20:61568..2269777 [GRCh37]
Chr20:20p13		 pathogenic
NM_001040023.2(SIRPA):c.1071C>T (p.Gly357=) single nucleotide variant not provided [RCV000893170] Chr20:1922629 [GRCh38]
Chr20:1903275 [GRCh37]
Chr20:20p13		 benign
GRCh37/hg19 20p13(chr20:1886492-2028451)x3 copy number gain not provided [RCV000846348] Chr20:1886492..2028451 [GRCh37]
Chr20:20p13		 uncertain significance
NM_001040023.2(SIRPA):c.613G>A (p.Val205Met) single nucleotide variant not specified [RCV004319190] Chr20:1921571 [GRCh38]
Chr20:1902217 [GRCh37]
Chr20:20p13		 uncertain significance
NM_001040023.2(SIRPA):c.1025G>C (p.Ser342Thr) single nucleotide variant not provided [RCV000883105] Chr20:1922583 [GRCh38]
Chr20:1903229 [GRCh37]
Chr20:20p13		 likely benign
NM_001040023.2(SIRPA):c.601G>A (p.Val201Ile) single nucleotide variant not provided [RCV000887181] Chr20:1921559 [GRCh38]
Chr20:1902205 [GRCh37]
Chr20:20p13		 benign
NM_001040023.2(SIRPA):c.1392G>A (p.Ser464=) single nucleotide variant not provided [RCV000897226] Chr20:1937445 [GRCh38]
Chr20:1918091 [GRCh37]
Chr20:20p13		 likely benign
NM_001040023.2(SIRPA):c.1380G>A (p.Pro460=) single nucleotide variant not provided [RCV000892755] Chr20:1937433 [GRCh38]
Chr20:1918079 [GRCh37]
Chr20:20p13		 benign
NM_001040023.2(SIRPA):c.1444C>T (p.Pro482Ser) single nucleotide variant not provided [RCV000958240] Chr20:1937497 [GRCh38]
Chr20:1918143 [GRCh37]
Chr20:20p13		 likely benign
GRCh37/hg19 20p13-11.1(chr20:61568-26305479)x3 copy number gain not provided [RCV001007068] Chr20:61568..26305479 [GRCh37]
Chr20:20p13-11.1		 pathogenic
GRCh37/hg19 20p13(chr20:1886492-2028451)x4 copy number gain not provided [RCV001258902] Chr20:1886492..2028451 [GRCh37]
Chr20:20p13		 uncertain significance
NM_001040023.2(SIRPA):c.1180G>A (p.Val394Ile) single nucleotide variant not specified [RCV004125984] Chr20:1924856 [GRCh38]
Chr20:1905502 [GRCh37]
Chr20:20p13		 uncertain significance
NM_001040023.2(SIRPA):c.587C>G (p.Thr196Ser) single nucleotide variant not specified [RCV004096464] Chr20:1921545 [GRCh38]
Chr20:1902191 [GRCh37]
Chr20:20p13		 uncertain significance
NM_001040023.2(SIRPA):c.1457C>T (p.Ala486Val) single nucleotide variant not specified [RCV004170237] Chr20:1937510 [GRCh38]
Chr20:1918156 [GRCh37]
Chr20:20p13		 uncertain significance
NM_001040023.2(SIRPA):c.908C>T (p.Thr303Ile) single nucleotide variant not specified [RCV004107691] Chr20:1922466 [GRCh38]
Chr20:1903112 [GRCh37]
Chr20:20p13		 uncertain significance
NM_001040023.2(SIRPA):c.842A>G (p.Gln281Arg) single nucleotide variant not specified [RCV004241687] Chr20:1922400 [GRCh38]
Chr20:1903046 [GRCh37]
Chr20:20p13		 uncertain significance
NM_001040023.2(SIRPA):c.664G>C (p.Val222Leu) single nucleotide variant not specified [RCV004172997] Chr20:1921622 [GRCh38]
Chr20:1902268 [GRCh37]
Chr20:20p13		 uncertain significance
NM_001040023.2(SIRPA):c.1495G>A (p.Val499Ile) single nucleotide variant not specified [RCV004143790] Chr20:1937548 [GRCh38]
Chr20:1918194 [GRCh37]
Chr20:20p13		 uncertain significance
NM_001040023.2(SIRPA):c.887C>T (p.Thr296Ile) single nucleotide variant not specified [RCV004157804] Chr20:1922445 [GRCh38]
Chr20:1903091 [GRCh37]
Chr20:20p13		 uncertain significance
NM_001040023.2(SIRPA):c.1496T>C (p.Val499Ala) single nucleotide variant not specified [RCV004216833] Chr20:1937549 [GRCh38]
Chr20:1918195 [GRCh37]
Chr20:20p13		 uncertain significance
NM_001040023.2(SIRPA):c.1211C>T (p.Ser404Phe) single nucleotide variant not specified [RCV004136129] Chr20:1927884 [GRCh38]
Chr20:1908530 [GRCh37]
Chr20:20p13		 uncertain significance
NM_001040023.2(SIRPA):c.1396G>A (p.Asp466Asn) single nucleotide variant not specified [RCV004125656] Chr20:1937449 [GRCh38]
Chr20:1918095 [GRCh37]
Chr20:20p13		 uncertain significance
NM_001040023.2(SIRPA):c.985C>G (p.Leu329Val) single nucleotide variant not specified [RCV004118613] Chr20:1922543 [GRCh38]
Chr20:1903189 [GRCh37]
Chr20:20p13		 uncertain significance
NM_001040023.2(SIRPA):c.1114A>T (p.Ile372Phe) single nucleotide variant not specified [RCV004137800] Chr20:1924790 [GRCh38]
Chr20:1905436 [GRCh37]
Chr20:20p13		 uncertain significance
NM_001040023.2(SIRPA):c.470C>T (p.Ala157Val) single nucleotide variant not specified [RCV004084133] Chr20:1921428 [GRCh38]
Chr20:1902074 [GRCh37]
Chr20:20p13		 uncertain significance
NM_001040023.2(SIRPA):c.748A>G (p.Ile250Val) single nucleotide variant not specified [RCV004258669] Chr20:1921706 [GRCh38]
Chr20:1902352 [GRCh37]
Chr20:20p13		 uncertain significance
NM_001040023.2(SIRPA):c.1107A>C (p.Glu369Asp) single nucleotide variant not specified [RCV004277781] Chr20:1924783 [GRCh38]
Chr20:1905429 [GRCh37]
Chr20:20p13		 uncertain significance
GRCh38/hg38 20p13-11.21(chr20:87153-23635465)x3 copy number gain Renal agenesis [RCV003327640] Chr20:87153..23635465 [GRCh38]
Chr20:20p13-11.21		 pathogenic
NM_001040023.2(SIRPA):c.857C>G (p.Thr286Ser) single nucleotide variant not specified [RCV004342463] Chr20:1922415 [GRCh38]
Chr20:1903061 [GRCh37]
Chr20:20p13		 uncertain significance
NM_001040023.2(SIRPA):c.487C>G (p.Gln163Glu) single nucleotide variant not specified [RCV004348633] Chr20:1921445 [GRCh38]
Chr20:1902091 [GRCh37]
Chr20:20p13		 likely benign
NM_001040023.2(SIRPA):c.1388C>G (p.Ala463Gly) single nucleotide variant not specified [RCV004338035] Chr20:1937441 [GRCh38]
Chr20:1918087 [GRCh37]
Chr20:20p13		 uncertain significance
NM_001040023.2(SIRPA):c.1424T>G (p.Met475Arg) single nucleotide variant not specified [RCV004360708] Chr20:1937477 [GRCh38]
Chr20:1918123 [GRCh37]
Chr20:20p13		 uncertain significance
NM_001040023.2(SIRPA):c.799A>G (p.Asn267Asp) single nucleotide variant not specified [RCV004356671] Chr20:1922357 [GRCh38]
Chr20:1903003 [GRCh37]
Chr20:20p13		 uncertain significance
NM_001040023.2(SIRPA):c.511G>A (p.Glu171Lys) single nucleotide variant not specified [RCV004343136] Chr20:1921469 [GRCh38]
Chr20:1902115 [GRCh37]
Chr20:20p13		 likely benign
NM_001040023.2(SIRPA):c.1363A>G (p.Ser455Gly) single nucleotide variant not specified [RCV004353683] Chr20:1937416 [GRCh38]
Chr20:1918062 [GRCh37]
Chr20:20p13		 uncertain significance
NM_001040023.2(SIRPA):c.496G>C (p.Val166Leu) single nucleotide variant not specified [RCV004363818] Chr20:1921454 [GRCh38]
Chr20:1902100 [GRCh37]
Chr20:20p13		 uncertain significance
GRCh37/hg19 20p13-12.2(chr20:61569-9542361)x3 copy number gain not provided [RCV003485207] Chr20:61569..9542361 [GRCh37]
Chr20:20p13-12.2		 pathogenic
Single allele deletion not provided [RCV003448677] Chr20:61001..2316914 [GRCh37]
Chr20:20p13		 pathogenic
GRCh37/hg19 20p13-12.1(chr20:68351-16142323)x3 copy number gain not provided [RCV003885494] Chr20:68351..16142323 [GRCh37]
Chr20:20p13-12.1		 pathogenic
NM_001040023.2(SIRPA):c.353C>T (p.Thr118Ile) single nucleotide variant not provided [RCV003886164] Chr20:1915372 [GRCh38]
Chr20:1896018 [GRCh37]
Chr20:20p13		 likely benign
GRCh37/hg19 20p13-11.21(chr20:68351-23860313)x3 copy number gain not provided [RCV003885495] Chr20:68351..23860313 [GRCh37]
Chr20:20p13-11.21		 pathogenic
NM_001040023.2(SIRPA):c.971G>C (p.Arg324Thr) single nucleotide variant not specified [RCV004453885] Chr20:1922529 [GRCh38]
Chr20:1903175 [GRCh37]
Chr20:20p13		 uncertain significance
NM_001040023.2(SIRPA):c.934T>A (p.Trp312Arg) single nucleotide variant not specified [RCV004453884] Chr20:1922492 [GRCh38]
Chr20:1903138 [GRCh37]
Chr20:20p13		 uncertain significance
NM_001040023.2(SIRPA):c.805G>T (p.Val269Leu) single nucleotide variant not specified [RCV004453883] Chr20:1922363 [GRCh38]
Chr20:1903009 [GRCh37]
Chr20:20p13		 uncertain significance
NM_001040023.2(SIRPA):c.1399A>G (p.Thr467Ala) single nucleotide variant not specified [RCV004453881] Chr20:1937452 [GRCh38]
Chr20:1918098 [GRCh37]
Chr20:20p13		 uncertain significance
NM_001040023.2(SIRPA):c.220C>T (p.Pro74Ser) single nucleotide variant not specified [RCV004453882] Chr20:1915239 [GRCh38]
Chr20:1895885 [GRCh37]
Chr20:20p13		 uncertain significance
NM_001040023.2(SIRPA):c.664G>A (p.Val222Ile) single nucleotide variant not specified [RCV004669917] Chr20:1921622 [GRCh38]
Chr20:1902268 [GRCh37]
Chr20:20p13		 uncertain significance
miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
MIR20Ahsa-miR-20a-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI23562609
MIR17hsa-miR-17-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI23562609
MIR106Ahsa-miR-106a-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI23562609

Predicted Target Of
Summary Value
Count of predictions:3468
Count of miRNA genes:705
Interacting mature miRNAs:782
Transcripts:ENST00000356025, ENST00000358771, ENST00000400068
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407293318GWAS942294_Htyrosine-protein phosphatase non-receptor type 1 measurement QTL GWAS942294 (human)4e-15tyrosine-protein phosphatase non-receptor type 1 measurement2019191801919181Human
407265285GWAS914261_Hbody height QTL GWAS914261 (human)1e-10body height (VT:0001253)body height (CMO:0000106)2019136891913690Human
407293315GWAS942291_Htyrosine-protein phosphatase non-receptor type 1 measurement QTL GWAS942291 (human)8e-18tyrosine-protein phosphatase non-receptor type 1 measurement2018985051898506Human
407293313GWAS942289_Htyrosine-protein phosphatase non-receptor type 1 measurement QTL GWAS942289 (human)2e-20tyrosine-protein phosphatase non-receptor type 1 measurement2019129241912925Human
406892743GWAS541719_Hbasophil percentage of granulocytes QTL GWAS541719 (human)4e-11basophil percentage of granulocytes2019399321939933Human
407122435GWAS771411_Hreticulocyte count QTL GWAS771411 (human)4e-13reticulocyte counttotal reticulocyte count (CMO:0003020)2019399591939960Human
407296271GWAS945247_Htyrosine-protein phosphatase non-receptor type 1 measurement QTL GWAS945247 (human)3e-287tyrosine-protein phosphatase non-receptor type 1 measurement2019082191908220Human
406965898GWAS614874_Hlevel of tyrosine-protein phosphatase non-receptor type substrate 1 in blood serum QTL GWAS614874 (human)7e-384level of tyrosine-protein phosphatase non-receptor type substrate 1 in blood serum2019036441903645Human
407293598GWAS942574_Htyrosine-protein phosphatase non-receptor type 1 measurement QTL GWAS942574 (human)3e-11tyrosine-protein phosphatase non-receptor type 1 measurement2019238691923870Human
407316441GWAS965417_Htyrosine-protein phosphatase non-receptor type 1 measurement QTL GWAS965417 (human)2e-62tyrosine-protein phosphatase non-receptor type 1 measurement2019044971904498Human
407316440GWAS965416_Htyrosine-protein phosphatase non-receptor type 1 measurement QTL GWAS965416 (human)4e-303tyrosine-protein phosphatase non-receptor type 1 measurement2019139601913961Human
407244901GWAS893877_Hcarotid artery intima media thickness QTL GWAS893877 (human)0.0000007carotid artery intima media thickness2019028051902806Human
407245026GWAS894002_Hlifestyle measurement, anxiety disorder measurement QTL GWAS894002 (human)1e-10lifestyle measurement, anxiety disorder measurement2018968121896813Human
407242594GWAS891570_Hcarotid artery intima media thickness QTL GWAS891570 (human)5e-08carotid artery intima media thickness2019028051902806Human
407192929GWAS841905_Htyrosine-protein phosphatase non-receptor type substrate 1 measurement QTL GWAS841905 (human)1e-5100tyrosine-protein phosphatase non-receptor type substrate 1 measurement2019124751912476Human
406892772GWAS541748_Htyrosine-protein phosphatase non-receptor type substrate 1 measurement QTL GWAS541748 (human)2e-822tyrosine-protein phosphatase non-receptor type substrate 1 measurement2019151801915181Human
406892773GWAS541749_Htyrosine-protein phosphatase non-receptor type substrate 1 measurement QTL GWAS541749 (human)8e-1361tyrosine-protein phosphatase non-receptor type substrate 1 measurement2019156421915643Human
407388705GWAS1037681_Htyrosine-protein phosphatase non-receptor type substrate 1 measurement QTL GWAS1037681 (human)1e-10tyrosine-protein phosphatase non-receptor type substrate 1 measurement2018965041896505Human
407388706GWAS1037682_Htyrosine-protein phosphatase non-receptor type substrate 1 measurement QTL GWAS1037682 (human)3e-106tyrosine-protein phosphatase non-receptor type substrate 1 measurement2019124751912476Human
406987564GWAS636540_Hlevel of tyrosine-protein phosphatase non-receptor type substrate 1 in blood serum QTL GWAS636540 (human)2e-263level of tyrosine-protein phosphatase non-receptor type substrate 1 in blood serum2019136891913690Human
407190647GWAS839623_Hplatelet measurement QTL GWAS839623 (human)3e-34platelet measurementplatelet measurement (CMO:0000921)2019399321939933Human
407293310GWAS942286_Htyrosine-protein phosphatase non-receptor type 1 measurement QTL GWAS942286 (human)5e-38tyrosine-protein phosphatase non-receptor type 1 measurement2018988031898804Human
407293311GWAS942287_Htyrosine-protein phosphatase non-receptor type 1 measurement QTL GWAS942287 (human)1e-37tyrosine-protein phosphatase non-receptor type 1 measurement2019164421916443Human
407091001GWAS739977_Hblood protein measurement QTL GWAS739977 (human)2e-1072blood protein measurementblood protein measurement (CMO:0000028)2019136891913690Human
407230201GWAS879177_Hbone density QTL GWAS879177 (human)1e-09bone mineral mass (VT:0005007)bone mineral density (CMO:0001226)2019379101937911Human
406992447GWAS641423_Hreticulocyte count QTL GWAS641423 (human)5e-16reticulocyte counttotal reticulocyte count (CMO:0003020)2019399591939960Human
407078333GWAS727309_Hmitochondrial DNA measurement QTL GWAS727309 (human)5e-12obsolete_red blood cell distribution widthred blood cell distribution width- standard deviation (CMO:0003232)2019399321939933Human
407327800GWAS976776_Hbeverage consumption measurement QTL GWAS976776 (human)5e-12beverage consumption measurementdrink intake measurement (CMO:0000771)2019149751914976Human

Markers in Region
RH68309  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37201,918,424 - 1,918,551UniSTSGRCh37
Build 36201,866,424 - 1,866,551RGDNCBI36
Celera201,982,402 - 1,982,529RGD
Cytogenetic Map20p13UniSTS
HuRef201,868,286 - 1,868,413UniSTS
D20S793  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37201,898,591 - 1,898,692UniSTSGRCh37
Build 36201,846,591 - 1,846,692RGDNCBI36
Celera201,962,569 - 1,962,670RGD
Cytogenetic Map20p13UniSTS
HuRef201,848,463 - 1,848,564UniSTS
TNG Radiation Hybrid Map201178.0UniSTS
Stanford-G3 RH Map20113.0UniSTS
NCBI RH Map2019.4UniSTS
PTPNS1_1575  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37201,919,811 - 1,920,707UniSTSGRCh37
Build 36201,867,811 - 1,868,707RGDNCBI36
Celera201,983,792 - 1,984,688RGD
HuRef201,869,679 - 1,870,575UniSTS
D20S203E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37201,920,280 - 1,920,457UniSTSGRCh37
Build 36201,868,280 - 1,868,457RGDNCBI36
Celera201,984,261 - 1,984,438RGD
Cytogenetic Map20p13UniSTS
HuRef201,870,148 - 1,870,325UniSTS
SHGC-31938  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37201,918,959 - 1,919,108UniSTSGRCh37
Build 36201,866,959 - 1,867,108RGDNCBI36
Celera201,982,940 - 1,983,089RGD
Cytogenetic Map20p13UniSTS
HuRef201,868,827 - 1,868,976UniSTS
GeneMap99-GB4 RH Map2011.04UniSTS
GeneMap99-GB4 RH Map2013.18UniSTS
Whitehead-RH Map2019.9UniSTS
NCBI RH Map209.8UniSTS
GeneMap99-G3 RH Map20118.0UniSTS
G18068  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37201,898,208 - 1,898,394UniSTSGRCh37
Build 36201,846,208 - 1,846,394RGDNCBI36
Celera201,962,186 - 1,962,372RGD
Cytogenetic Map20p13UniSTS
HuRef201,848,080 - 1,848,266UniSTS
BCD2069  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37201,920,330 - 1,920,429UniSTSGRCh37
Build 36201,868,330 - 1,868,429RGDNCBI36
Celera201,984,311 - 1,984,410RGD
Cytogenetic Map20p13UniSTS
HuRef201,870,198 - 1,870,297UniSTS
GeneMap99-GB4 RH Map2011.04UniSTS
WI-14028  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37201,903,263 - 1,903,362UniSTSGRCh37
Build 36201,851,263 - 1,851,362RGDNCBI36
Celera201,967,241 - 1,967,340RGD
Cytogenetic Map20p13UniSTS
HuRef201,853,133 - 1,853,232UniSTS
GeneMap99-GB4 RH Map2010.26UniSTS
GeneMap99-GB4 RH Map2011.14UniSTS
Whitehead-RH Map2019.9UniSTS
NCBI RH Map2028.2UniSTS
STS-M78966  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37201,919,114 - 1,919,215UniSTSGRCh37
Build 36201,867,114 - 1,867,215RGDNCBI36
Celera201,983,095 - 1,983,196RGD
Cytogenetic Map20p13UniSTS
HuRef201,868,982 - 1,869,083UniSTS
GeneMap99-GB4 RH Map2012.19UniSTS
D20S1066  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37201,920,287 - 1,920,519UniSTSGRCh37
Build 36201,868,287 - 1,868,519RGDNCBI36
Celera201,984,268 - 1,984,500RGD
Cytogenetic Map20p13UniSTS
HuRef201,870,155 - 1,870,387UniSTS
GeneMap99-GB4 RH Map209.78UniSTS
GeneMap99-GB4 RH Map2010.26UniSTS
Whitehead-RH Map2015.1UniSTS
Whitehead-YAC Contig Map20 UniSTS
RH11752  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37201,920,287 - 1,920,428UniSTSGRCh37
Build 36201,868,287 - 1,868,428RGDNCBI36
Celera201,984,268 - 1,984,409RGD
Cytogenetic Map20p13UniSTS
HuRef201,870,155 - 1,870,296UniSTS
GeneMap99-GB4 RH Map2015.0UniSTS
NCBI RH Map2028.8UniSTS
STS-D29515  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37201,918,748 - 1,918,997UniSTSGRCh37
Build 36201,866,748 - 1,866,997RGDNCBI36
Celera201,982,729 - 1,982,978RGD
Cytogenetic Map20p13UniSTS
HuRef201,868,616 - 1,868,865UniSTS
GeneMap99-GB4 RH Map2011.04UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2411 2788 2238 4965 1720 2326 4 623 1883 464 2268 7212 6400 52 3729 1 850 1737 1592 173 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001040022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001040023 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001330728 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_080792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005260670 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006723545 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011529173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024451836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047439915 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047439916 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047439917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047439918 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047439919 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047439920 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054323047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054323048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054323049 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054323050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054323051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054323052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054323053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054323054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB023430 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK290776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK298243 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK312521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL034562 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL117335 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC026692 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC033092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC038510 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC075849 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471133 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068258 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D86043 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA471662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DN989886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U06681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U06701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y10375 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y11047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000356025   ⟹   ENSP00000348307
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl201,894,783 - 1,939,897 (+)Ensembl
Ensembl Acc Id: ENST00000358771   ⟹   ENSP00000351621
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl201,895,407 - 1,940,592 (+)Ensembl
Ensembl Acc Id: ENST00000400068   ⟹   ENSP00000382941
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl201,894,167 - 1,939,894 (+)Ensembl
Ensembl Acc Id: ENST00000622179   ⟹   ENSP00000478763
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl201,894,508 - 1,940,592 (+)Ensembl
RefSeq Acc Id: NM_001040022   ⟹   NP_001035111
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38201,894,167 - 1,939,894 (+)NCBI
GRCh37201,874,763 - 1,920,540 (+)NCBI
Build 36201,822,813 - 1,868,540 (+)NCBI Archive
HuRef201,824,406 - 1,870,408 (+)ENTREZGENE
CHM1_1201,875,015 - 1,920,758 (+)NCBI
T2T-CHM13v2.0201,924,358 - 1,970,071 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001040023   ⟹   NP_001035112
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38201,895,407 - 1,940,592 (+)NCBI
GRCh37201,874,763 - 1,920,540 (+)NCBI
Build 36201,823,826 - 1,868,540 (+)NCBI Archive
HuRef201,824,406 - 1,870,408 (+)ENTREZGENE
CHM1_1201,876,028 - 1,920,758 (+)NCBI
T2T-CHM13v2.0201,925,598 - 1,970,769 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001330728   ⟹   NP_001317657
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38201,894,167 - 1,939,894 (+)NCBI
T2T-CHM13v2.0201,924,358 - 1,970,071 (+)NCBI
Sequence:
RefSeq Acc Id: NM_080792   ⟹   NP_542970
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38201,894,742 - 1,940,592 (+)NCBI
GRCh37201,874,763 - 1,920,540 (+)NCBI
Build 36201,823,425 - 1,868,540 (+)NCBI Archive
HuRef201,824,406 - 1,870,408 (+)ENTREZGENE
CHM1_1201,875,627 - 1,920,758 (+)NCBI
T2T-CHM13v2.0201,924,933 - 1,970,769 (+)NCBI
Sequence:
RefSeq Acc Id: XM_005260670   ⟹   XP_005260727
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38201,894,742 - 1,940,592 (+)NCBI
GRCh37201,874,763 - 1,920,540 (+)NCBI
Sequence:
RefSeq Acc Id: XM_011529173   ⟹   XP_011527475
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38201,896,839 - 1,940,592 (+)NCBI
Sequence:
RefSeq Acc Id: XM_024451836   ⟹   XP_024307604
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38201,894,936 - 1,940,592 (+)NCBI
Sequence:
RefSeq Acc Id: XM_047439915   ⟹   XP_047295871
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38201,895,407 - 1,940,592 (+)NCBI
RefSeq Acc Id: XM_047439916   ⟹   XP_047295872
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38201,894,936 - 1,940,592 (+)NCBI
RefSeq Acc Id: XM_047439917   ⟹   XP_047295873
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38201,894,167 - 1,940,592 (+)NCBI
RefSeq Acc Id: XM_047439918   ⟹   XP_047295874
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38201,894,936 - 1,940,592 (+)NCBI
RefSeq Acc Id: XM_047439919   ⟹   XP_047295875
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38201,894,167 - 1,940,592 (+)NCBI
RefSeq Acc Id: XM_047439920   ⟹   XP_047295876
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38201,894,936 - 1,940,592 (+)NCBI
RefSeq Acc Id: XM_054323047   ⟹   XP_054179022
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0201,924,933 - 1,970,769 (+)NCBI
RefSeq Acc Id: XM_054323048   ⟹   XP_054179023
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0201,925,091 - 1,970,769 (+)NCBI
RefSeq Acc Id: XM_054323049   ⟹   XP_054179024
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0201,944,468 - 1,970,769 (+)NCBI
RefSeq Acc Id: XM_054323050   ⟹   XP_054179025
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0201,925,103 - 1,970,769 (+)NCBI
RefSeq Acc Id: XM_054323051   ⟹   XP_054179026
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0201,924,358 - 1,970,769 (+)NCBI
RefSeq Acc Id: XM_054323052   ⟹   XP_054179027
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0201,925,081 - 1,970,769 (+)NCBI
RefSeq Acc Id: XM_054323053   ⟹   XP_054179028
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0201,924,358 - 1,970,769 (+)NCBI
RefSeq Acc Id: XM_054323054   ⟹   XP_054179029
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0201,925,103 - 1,970,769 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001035111 (Get FASTA)   NCBI Sequence Viewer  
  NP_001035112 (Get FASTA)   NCBI Sequence Viewer  
  NP_001317657 (Get FASTA)   NCBI Sequence Viewer  
  NP_542970 (Get FASTA)   NCBI Sequence Viewer  
  XP_005260727 (Get FASTA)   NCBI Sequence Viewer  
  XP_011527475 (Get FASTA)   NCBI Sequence Viewer  
  XP_024307604 (Get FASTA)   NCBI Sequence Viewer  
  XP_047295871 (Get FASTA)   NCBI Sequence Viewer  
  XP_047295872 (Get FASTA)   NCBI Sequence Viewer  
  XP_047295873 (Get FASTA)   NCBI Sequence Viewer  
  XP_047295874 (Get FASTA)   NCBI Sequence Viewer  
  XP_047295875 (Get FASTA)   NCBI Sequence Viewer  
  XP_047295876 (Get FASTA)   NCBI Sequence Viewer  
  XP_054179022 (Get FASTA)   NCBI Sequence Viewer  
  XP_054179023 (Get FASTA)   NCBI Sequence Viewer  
  XP_054179024 (Get FASTA)   NCBI Sequence Viewer  
  XP_054179025 (Get FASTA)   NCBI Sequence Viewer  
  XP_054179026 (Get FASTA)   NCBI Sequence Viewer  
  XP_054179027 (Get FASTA)   NCBI Sequence Viewer  
  XP_054179028 (Get FASTA)   NCBI Sequence Viewer  
  XP_054179029 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH26692 (Get FASTA)   NCBI Sequence Viewer  
  AAH33092 (Get FASTA)   NCBI Sequence Viewer  
  AAH38510 (Get FASTA)   NCBI Sequence Viewer  
  AAH75849 (Get FASTA)   NCBI Sequence Viewer  
  BAA12974 (Get FASTA)   NCBI Sequence Viewer  
  BAA87929 (Get FASTA)   NCBI Sequence Viewer  
  BAF83465 (Get FASTA)   NCBI Sequence Viewer  
  BAG35420 (Get FASTA)   NCBI Sequence Viewer  
  BAG60509 (Get FASTA)   NCBI Sequence Viewer  
  CAA71403 (Get FASTA)   NCBI Sequence Viewer  
  CAA71944 (Get FASTA)   NCBI Sequence Viewer  
  EAX10606 (Get FASTA)   NCBI Sequence Viewer  
  EAX10607 (Get FASTA)   NCBI Sequence Viewer  
  EAX10608 (Get FASTA)   NCBI Sequence Viewer  
  EAX10609 (Get FASTA)   NCBI Sequence Viewer  
  EAX10610 (Get FASTA)   NCBI Sequence Viewer  
  EAX10611 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000348307
  ENSP00000348307.3
  ENSP00000351621
  ENSP00000351621.4
  ENSP00000382941
  ENSP00000382941.4
  ENSP00000478763
  ENSP00000478763.1
GenBank Protein P78324 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001035111   ⟸   NM_001040022
- Peptide Label: isoform 1 precursor
- UniProtKB: Q9Y4U9 (UniProtKB/Swiss-Prot),   Q9UIJ6 (UniProtKB/Swiss-Prot),   Q9UDX2 (UniProtKB/Swiss-Prot),   Q9H0Z2 (UniProtKB/Swiss-Prot),   Q8TAL8 (UniProtKB/Swiss-Prot),   Q8N517 (UniProtKB/Swiss-Prot),   A2A2E1 (UniProtKB/Swiss-Prot),   P78324 (UniProtKB/Swiss-Prot),   O43799 (UniProtKB/Swiss-Prot),   O00683 (UniProtKB/Swiss-Prot),   B2R6C3 (UniProtKB/Swiss-Prot),   A8K411 (UniProtKB/Swiss-Prot),   B4DP97 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001035112   ⟸   NM_001040023
- Peptide Label: isoform 1 precursor
- UniProtKB: Q9Y4U9 (UniProtKB/Swiss-Prot),   Q9UIJ6 (UniProtKB/Swiss-Prot),   Q9UDX2 (UniProtKB/Swiss-Prot),   Q9H0Z2 (UniProtKB/Swiss-Prot),   Q8TAL8 (UniProtKB/Swiss-Prot),   Q8N517 (UniProtKB/Swiss-Prot),   P78324 (UniProtKB/Swiss-Prot),   O43799 (UniProtKB/Swiss-Prot),   O00683 (UniProtKB/Swiss-Prot),   B2R6C3 (UniProtKB/Swiss-Prot),   A8K411 (UniProtKB/Swiss-Prot),   A2A2E1 (UniProtKB/Swiss-Prot),   B4DP97 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_542970   ⟸   NM_080792
- Peptide Label: isoform 1 precursor
- UniProtKB: Q9Y4U9 (UniProtKB/Swiss-Prot),   Q9UIJ6 (UniProtKB/Swiss-Prot),   Q9UDX2 (UniProtKB/Swiss-Prot),   Q9H0Z2 (UniProtKB/Swiss-Prot),   Q8TAL8 (UniProtKB/Swiss-Prot),   Q8N517 (UniProtKB/Swiss-Prot),   P78324 (UniProtKB/Swiss-Prot),   O43799 (UniProtKB/Swiss-Prot),   O00683 (UniProtKB/Swiss-Prot),   B2R6C3 (UniProtKB/Swiss-Prot),   A8K411 (UniProtKB/Swiss-Prot),   A2A2E1 (UniProtKB/Swiss-Prot),   B4DP97 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005260727   ⟸   XM_005260670
- Peptide Label: isoform X1
- UniProtKB: B4DP97 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011527475   ⟸   XM_011529173
- Peptide Label: isoform X2
- UniProtKB: B4DP97 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001317657   ⟸   NM_001330728
- Peptide Label: isoform 2 precursor
- UniProtKB: B4DP97 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_024307604   ⟸   XM_024451836
- Peptide Label: isoform X1
- UniProtKB: B4DP97 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000478763   ⟸   ENST00000622179
Ensembl Acc Id: ENSP00000382941   ⟸   ENST00000400068
Ensembl Acc Id: ENSP00000348307   ⟸   ENST00000356025
Ensembl Acc Id: ENSP00000351621   ⟸   ENST00000358771
RefSeq Acc Id: XP_047295873   ⟸   XM_047439917
- Peptide Label: isoform X4
RefSeq Acc Id: XP_047295875   ⟸   XM_047439919
- Peptide Label: isoform X5
RefSeq Acc Id: XP_047295872   ⟸   XM_047439916
- Peptide Label: isoform X3
- UniProtKB: Q9Y4U9 (UniProtKB/Swiss-Prot),   Q9UIJ6 (UniProtKB/Swiss-Prot),   Q9UDX2 (UniProtKB/Swiss-Prot),   Q9H0Z2 (UniProtKB/Swiss-Prot),   Q8TAL8 (UniProtKB/Swiss-Prot),   Q8N517 (UniProtKB/Swiss-Prot),   P78324 (UniProtKB/Swiss-Prot),   O43799 (UniProtKB/Swiss-Prot),   O00683 (UniProtKB/Swiss-Prot),   B2R6C3 (UniProtKB/Swiss-Prot),   A8K411 (UniProtKB/Swiss-Prot),   A2A2E1 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_047295874   ⟸   XM_047439918
- Peptide Label: isoform X4
RefSeq Acc Id: XP_047295876   ⟸   XM_047439920
- Peptide Label: isoform X5
RefSeq Acc Id: XP_047295871   ⟸   XM_047439915
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054179026   ⟸   XM_054323051
- Peptide Label: isoform X4
RefSeq Acc Id: XP_054179028   ⟸   XM_054323053
- Peptide Label: isoform X5
RefSeq Acc Id: XP_054179022   ⟸   XM_054323047
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054179027   ⟸   XM_054323052
- Peptide Label: isoform X4
RefSeq Acc Id: XP_054179023   ⟸   XM_054323048
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054179025   ⟸   XM_054323050
- Peptide Label: isoform X3
RefSeq Acc Id: XP_054179029   ⟸   XM_054323054
- Peptide Label: isoform X5
RefSeq Acc Id: XP_054179024   ⟸   XM_054323049
- Peptide Label: isoform X2
Protein Domains
Ig-like   Ig-like C1-type   Ig-like V-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P78324-F1-model_v2 AlphaFold P78324 1-504 view protein structure

Promoters
RGD ID:6799053
Promoter ID:HG_KWN:38357
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lymphoblastoid,   NB4
Transcripts:ENST00000358771,   NM_001040022,   OTTHUMT00000251762,   OTTHUMT00000251763,   UC002WFT.1
Position:
Human AssemblyChrPosition (strand)Source
Build 36201,823,274 - 1,823,774 (+)MPROMDB
RGD ID:13206149
Promoter ID:EPDNEW_H26655
Type:initiation region
Name:SIRPA_2
Description:signal regulatory protein alpha
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H26656  EPDNEW_H26657  EPDNEW_H26658  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38201,894,117 - 1,894,177EPDNEW
RGD ID:13206151
Promoter ID:EPDNEW_H26656
Type:initiation region
Name:SIRPA_1
Description:signal regulatory protein alpha
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H26655  EPDNEW_H26657  EPDNEW_H26658  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38201,894,488 - 1,894,548EPDNEW
RGD ID:13206153
Promoter ID:EPDNEW_H26657
Type:initiation region
Name:SIRPA_4
Description:signal regulatory protein alpha
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H26655  EPDNEW_H26656  EPDNEW_H26658  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38201,894,708 - 1,894,768EPDNEW
RGD ID:13206155
Promoter ID:EPDNEW_H26658
Type:initiation region
Name:SIRPA_3
Description:signal regulatory protein alpha
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H26655  EPDNEW_H26656  EPDNEW_H26657  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38201,895,379 - 1,895,439EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:9662 AgrOrtholog
COSMIC SIRPA COSMIC
Ensembl Genes ENSG00000198053 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000356025 ENTREZGENE
  ENST00000356025.7 UniProtKB/Swiss-Prot
  ENST00000358771 ENTREZGENE
  ENST00000358771.5 UniProtKB/Swiss-Prot
  ENST00000400068 ENTREZGENE
  ENST00000400068.7 UniProtKB/Swiss-Prot
  ENST00000622179 ENTREZGENE
  ENST00000622179.4 UniProtKB/Swiss-Prot
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000198053 GTEx
HGNC ID HGNC:9662 ENTREZGENE
Human Proteome Map SIRPA Human Proteome Map
InterPro Ig-like_CS_Receptor UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_C1-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_V-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:140885 UniProtKB/Swiss-Prot
NCBI Gene SIRPA ENTREZGENE
OMIM 602461 OMIM
PANTHER SIGNAL-REGULATORY PROTEIN BETA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE SUBSTRATE 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam C1-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  V-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA34006 PharmGKB
PROSITE IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART IGc1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IGv UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Immunoglobulin UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
UniProt A2A2E1 ENTREZGENE
  A8K411 ENTREZGENE
  B2R6C3 ENTREZGENE
  B4DP97 ENTREZGENE, UniProtKB/TrEMBL
  O00683 ENTREZGENE
  O43799 ENTREZGENE
  P78324 ENTREZGENE
  Q8N517 ENTREZGENE
  Q8TAL8 ENTREZGENE
  Q9H0Z2 ENTREZGENE
  Q9UDX2 ENTREZGENE
  Q9UIJ6 ENTREZGENE
  Q9Y4U9 ENTREZGENE
  SHPS1_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary A2A2E1 UniProtKB/Swiss-Prot
  A8K411 UniProtKB/Swiss-Prot
  B2R6C3 UniProtKB/Swiss-Prot
  O00683 UniProtKB/Swiss-Prot
  O43799 UniProtKB/Swiss-Prot
  Q8N517 UniProtKB/Swiss-Prot
  Q8TAL8 UniProtKB/Swiss-Prot
  Q9H0Z2 UniProtKB/Swiss-Prot
  Q9UDX2 UniProtKB/Swiss-Prot
  Q9UIJ6 UniProtKB/Swiss-Prot
  Q9Y4U9 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-26 SIRPA  signal regulatory protein alpha  SIRPA  signal-regulatory protein alpha  Symbol and/or name change 5135510 APPROVED