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Gene: MAPK11 (mitogen-activated protein kinase 11) Homo sapiens
Symbol: MAPK11
Name: mitogen-activated protein kinase 11
Description: Exhibits MAP kinase activity. Involved in several processes, including cellular response to interleukin-1; positive regulation of interleukin-12 production; and stress-activated MAPK cascade. Predicted to localize to cytoplasm and nucleus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: MAP kinase 11; MAP kinase p38 beta; MAPK 11; mitogen-activated protein kinase p38 beta; mitogen-activated protein kinase p38-2; p38-2; P38B; p38Beta; P38BETA2; PRKM11; SAPK2; SAPK2B; stress-activated protein kinase 2; stress-activated protein kinase 2b; stress-activated protein kinase-2; stress-activated protein kinase-2b
Mus musculus (house mouse) : Mapk11 (mitogen-activated protein kinase 11)  MGI  Alliance
Rattus norvegicus (Norway rat) : Mapk11 (mitogen-activated protein kinase 11)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mapk11 (mitogen-activated protein kinase 11)
Pan paniscus (bonobo/pygmy chimpanzee) : MAPK11 (mitogen-activated protein kinase 11)
Canis lupus familiaris (dog) : MAPK11 (mitogen-activated protein kinase 11)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mapk11 (mitogen-activated protein kinase 11)
Sus scrofa (pig) : MAPK11 (mitogen-activated protein kinase 11)
Chlorocebus sabaeus (African green monkey) : MAPK11 (mitogen-activated protein kinase 11)
Heterocephalus glaber (naked mole-rat) : Mapk11 (mitogen-activated protein kinase 11)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2250,263,713 - 50,270,767 (-)EnsemblGRCh38hg38GRCh38
GRCh382250,263,713 - 50,270,380 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372250,702,142 - 50,708,779 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362249,044,269 - 49,050,906 (-)NCBINCBI36hg18NCBI36
Build 342249,004,599 - 49,011,236NCBI
Celera2234,577,045 - 34,583,684 (-)NCBI
Cytogenetic Map22q13.33NCBI
HuRef2233,599,558 - 33,605,992 (-)NCBIHuRef
CHM1_12250,660,928 - 50,667,608 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on MAPK11
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1319634
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.