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Gene: CSNK2A1 (casein kinase 2 alpha 1) Homo sapiens
Symbol: CSNK2A1
Name: casein kinase 2 alpha 1
RGD ID: 733323
Description: Exhibits identical protein binding activity; protein N-terminus binding activity; and protein serine/threonine kinase activity. Involved in several processes, including negative regulation of proteolysis; positive regulation of Wnt signaling pathway; and protein phosphorylation. Localizes to NuRD complex; Sin3 complex; and protein kinase CK2 complex. Colocalizes with PcG protein complex. Biomarker of breast cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: casein kinase 2, alpha 1 polypeptide; casein kinase II alpha 1 polypeptide pseudogene; casein kinase II alpha 1 subunit; casein kinase II subunit alpha; casein kinase ii, alpha 1 polypeptide; CK II alpha; CK II alpha 3; CK2 catalytic subunit alpha; CK2A1; Cka1; Cka2; CKII; CSNK2A3; OCNDS; protein kinase CK2
Mus musculus (house mouse) : Csnk2a1 (casein kinase 2, alpha 1 polypeptide)  MGI  Alliance
Rattus norvegicus (Norway rat) : Csnk2a1 (casein kinase 2 alpha 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Csnk2a1 (casein kinase 2 alpha 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CSNK2A1 (casein kinase 2 alpha 1)
Canis lupus familiaris (dog) : CSNK2A1 (casein kinase 2 alpha 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Csnk2a1 (casein kinase 2 alpha 1)
Sus scrofa (pig) : CSNK2A1 (casein kinase 2 alpha 1)
Chlorocebus sabaeus (African green monkey) : CSNK2A1 (casein kinase 2 alpha 1)
Heterocephalus glaber (naked mole-rat) : Csnk2a1 (casein kinase 2 alpha 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl20472,498 - 543,835 (-)EnsemblGRCh38hg38GRCh38
GRCh3820472,498 - 543,790 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3720463,338 - 524,482 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3620411,338 - 472,482 (-)NCBINCBI36hg18NCBI36
Build 3420411,337 - 472,482NCBI
Celera20558,168 - 619,315 (-)NCBI
Cytogenetic Map20p13NCBI
HuRef20414,534 - 475,783 (-)NCBIHuRef
CHM1_120463,361 - 524,481 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CSNK2A1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733323
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-10-06
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.