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Gene: ECSIT (ECSIT signaling integrator) Homo sapiens
Symbol: ECSIT
Name: ECSIT signaling integrator
Description: Exhibits oxidoreductase activity, acting on NAD(P)H. Involved in regulation of oxidoreductase activity. Localizes to the cytosol; mitochondrion; and nucleoplasm; PARTICIPATES IN mitogen activated protein kinase signaling pathway; INTERACTS WITH cisplatin; cyclosporin A; disodium selenite.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ECSIT homolog; ECSIT signalling integrator; evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial; likely ortholog of mouse signaling intermediate in Toll pathway evolutionarily conserved; signaling intermediate in Toll pathway evolutionarily conserved ortholog; signaling intermediate in Toll pathway, evolutionarily conserved; SITPEC
Mus musculus (house mouse) : Ecsit (ECSIT signalling integrator)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ecsit (ECSIT signaling integrator)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ecsit (ECSIT signaling integrator)
Pan paniscus (bonobo/pygmy chimpanzee) : ECSIT (ECSIT signaling integrator)
Canis lupus familiaris (dog) : ECSIT (ECSIT signaling integrator)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ecsit (ECSIT signaling integrator)
Sus scrofa (pig) : ECSIT (ECSIT signaling integrator)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381911,505,916 - 11,529,134 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371911,616,731 - 11,639,987 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361911,477,744 - 11,500,930 (-)NCBINCBI36hg18NCBI36
Celera1911,511,487 - 11,534,729 (-)NCBI
Cytogenetic Map19p13.2NCBI
HuRef1911,191,504 - 11,214,699 (-)NCBIHuRef
CHM1_11911,616,796 - 11,640,052 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ECSIT
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1602709
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.