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Gene: ECSIT (ECSIT signaling integrator) Homo sapiens
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Symbol: ECSIT
Name: ECSIT signaling integrator
Description: Exhibits oxidoreductase activity, acting on NAD(P)H. Involved in regulation of oxidoreductase activity. Localizes to the cytosol; mitochondrion; and nucleoplasm; PARTICIPATES IN mitogen activated protein kinase signaling pathway; INTERACTS WITH cisplatin; cyclosporin A; disodium selenite.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ECSIT homolog; ECSIT signalling integrator; evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial; likely ortholog of mouse signaling intermediate in Toll pathway evolutionarily conserved; signaling intermediate in Toll pathway evolutionarily conserved ortholog; signaling intermediate in Toll pathway, evolutionarily conserved; SITPEC
Orthologs:
Mus musculus (house mouse) : Ecsit (ECSIT signalling integrator)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ecsit (ECSIT signaling integrator)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ecsit (ECSIT signaling integrator)
Pan paniscus (bonobo/pygmy chimpanzee) : ECSIT (ECSIT signaling integrator)
Canis lupus familiaris (dog) : ECSIT (ECSIT signaling integrator)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ecsit (ECSIT signaling integrator)
Sus scrofa (pig) : ECSIT (ECSIT signaling integrator)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381911,505,916 - 11,529,134 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371911,616,731 - 11,639,987 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361911,477,744 - 11,500,930 (-)NCBINCBI36hg18NCBI36
Celera1911,511,487 - 11,534,729 (-)NCBI
Cytogenetic Map19p13.2NCBI
HuRef1911,191,504 - 11,214,699 (-)NCBIHuRef
CHM1_11911,616,796 - 11,640,052 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ECSIT
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1602709
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.