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Gene: DGCR8 (DGCR8 microprocessor complex subunit) Homo sapiens
Symbol: DGCR8
Name: DGCR8 microprocessor complex subunit
Description: Exhibits RNA binding activity; heme binding activity; and protein homodimerization activity. Contributes to ribonuclease III activity. Involved in primary miRNA processing. Localizes to cytoplasm and microprocessor complex.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C22orf12; chromosome 22 open reading frame 12; DGCR8, microprocessor complex subunit; DGCRK6; DiGeorge syndrome critical region 8; DiGeorge syndrome critical region gene 8; Gy1; microprocessor complex subunit DGCR8; pasha
Mus musculus (house mouse) : Dgcr8 (DGCR8, microprocessor complex subunit)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dgcr8 (DGCR8 microprocessor complex subunit)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dgcr8 (DGCR8 microprocessor complex subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : DGCR8 (DGCR8 microprocessor complex subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dgcr8 (DGCR8 microprocessor complex subunit)
Sus scrofa (pig) : DGCR8 (DGCR8 microprocessor complex subunit)
Chlorocebus sabaeus (African green monkey) : DGCR8 (DGCR8 microprocessor complex subunit)
Heterocephalus glaber (naked mole-rat) : Dgcr8 (DGCR8 microprocessor complex subunit)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl2220,080,232 - 20,111,877 (+)EnsemblGRCh38hg38GRCh38
GRCh382220,080,232 - 20,111,877 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372220,067,755 - 20,099,400 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362218,447,834 - 18,479,400 (+)NCBINCBI36hg18NCBI36
Build 342218,442,387 - 18,473,952NCBI
Celera223,919,807 - 3,951,450 (+)NCBI
Cytogenetic Map22q11.21NCBI
HuRef223,688,418 - 3,720,061 (+)NCBIHuRef
CHM1_12220,067,440 - 20,099,084 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on DGCR8
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1314941
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.