GLRX2 (glutaredoxin 2) - Rat Genome Database

Name: GLRX2
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: GLRX2 (glutaredoxin 2) Homo sapiens

Analyze

Symbol:

GLRX2

Name:

glutaredoxin 2

RGD ID:

1317443

HGNC Page

HGNC

Description:

Predicted to have arsenate reductase (glutaredoxin) activity; glutathione disulfide oxidoreductase activity; and protein disulfide isomerase activity. Involved in response to hydrogen peroxide and response to organic substance. Localizes to mitochondrion and nucleoplasm.

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

bA101E13.1; bA101E13.1 (GRX2 glutaredoxin (thioltransferase) 2); CGI-133; glutaredoxin (thioltransferase) 2; glutaredoxin-2, mitochondrial; GRX2

RGD Orthologs

Mouse

Rat

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Mus musculus (house mouse):	Glrx2 (glutaredoxin 2 (thioltransferase))	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Glrx2 (glutaredoxin 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OrthoDB, OrthoMCL, Panther
Chinchilla lanigera (long-tailed chinchilla):	Glrx2 (glutaredoxin 2)	NCBI	Ortholog
Pan paniscus (bonobo/pygmy chimpanzee):	GLRX2 (glutaredoxin 2)	NCBI	Ortholog
Canis lupus familiaris (dog):	GLRX2 (glutaredoxin 2)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Glrx2 (glutaredoxin 2)	NCBI	Ortholog
Sus scrofa (pig):	GLRX2 (glutaredoxin 2)	HGNC	Ensembl, NCBI, OrthoDB
Chlorocebus sabaeus (African green monkey):	GLRX2 (glutaredoxin 2)	NCBI	Ortholog
Heterocephalus glaber (naked mole-rat):	Glrx2 (glutaredoxin 2)	NCBI	Ortholog
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Glrx2 (glutaredoxin 2)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)
Mus musculus (house mouse):	Glrx2 (glutaredoxin 2 (thioltransferase))	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|Roundup\|TreeFam)
Danio rerio (zebrafish):	glrx2 (glutaredoxin 2)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|Roundup\|ZFIN)
Saccharomyces cerevisiae (baker's yeast):	GRX1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|Roundup)
Drosophila melanogaster (fruit fly):	Grx1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|Roundup)
Drosophila melanogaster (fruit fly):	Grx1t	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PhylomeDB\|Roundup)
Caenorhabditis elegans (roundworm):	glrx-21	Alliance	DIOPT (InParanoid\|OrthoInspector\|PANTHER\|Roundup\|TreeFam)
Saccharomyces cerevisiae (baker's yeast):	GRX2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PhylomeDB\|Roundup)
Caenorhabditis elegans (roundworm):	glrx-22	Alliance	DIOPT (InParanoid\|OrthoInspector\|PANTHER\|TreeFam)

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	1	193,090,866 - 193,106,114 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	1	193,096,465 - 193,106,114 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	1	193,065,595 - 193,075,659 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	191,332,223 - 191,341,867 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	1	189,797,256 - 189,806,213	NCBI
Celera	1	166,175,205 - 166,184,851 (-)	NCBI
Cytogenetic Map	1	q31.2	NCBI
HuRef	1	164,301,400 - 164,311,051 (-)	NCBI		HuRef
CHM1_1	1	194,487,507 - 194,497,577 (-)	NCBI		CHM1_1

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Hyperparathyroidism 1 (IAGP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-epigallocatechin 3-gallate (EXP)

1,2-dichloroethane (ISO)

17beta-hydroxy-5alpha-androstan-3-one (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,6-dinitrotoluene (ISO)

2-hydroxypropanoic acid (EXP)

3,3',4,4',5-pentachlorobiphenyl (ISO)

3,4-methylenedioxymethamphetamine (ISO)

acetamide (ISO)

benzo[a]pyrene (EXP,ISO)

bisphenol A (EXP,ISO)

carbamazepine (EXP)

carbon nanotube (ISO)

chlordecone (ISO)

cisplatin (EXP)

copper atom (EXP)

copper(0) (EXP)

crocidolite asbestos (ISO)

Diallyl sulfide (ISO)

dibenzo[a,l]pyrene (EXP)

disulfiram (EXP)

diuron (ISO)

dorsomorphin (EXP)

elemental selenium (ISO)

finasteride (ISO)

flutamide (ISO)

genistein (EXP)

hexane (ISO)

isotretinoin (EXP)

mercury dibromide (EXP)

methyl methanesulfonate (EXP)

methylene blue (ISO)

methylmercury chloride (EXP)

mono(2-ethylhexyl) phthalate (EXP)

nefazodone (ISO)

nimesulide (ISO)

panobinostat (EXP)

paraquat (ISO)

phenobarbital (ISO)

phenylmercury acetate (EXP)

phlorizin (ISO)

pirinixic acid (ISO)

potassium chromate (EXP)

quercetin (EXP)

rac-lactic acid (EXP)

resveratrol (EXP)

SB 431542 (EXP)

selenium atom (ISO)

sunitinib (EXP)

toluene (ISO)

trichloroethene (ISO)

trichostatin A (EXP)

valproic acid (EXP)

vinclozolin (ISO)

zearalenone (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

aging (IEA)

apoptotic process (NAS)

cell differentiation (NAS)

cell redox homeostasis (TAS)

cellular response to superoxide (IEA)

DNA protection (NAS)

electron transport chain (IEA)

glutathione metabolic process (TAS)

protein phosphopantetheinylation (IEA)

regulation of signal transduction (NAS)

regulation of transcription, DNA-templated (NAS)

response to hydrogen peroxide (IDA)

response to organic substance (IDA)

response to redox state (TAS)

response to temperature stimulus (NAS)

Cellular Component

dendrite (IEA)

intracellular membrane-bounded organelle (IDA)

mitochondrial matrix (IEA)

mitochondrion (IDA)

neuronal cell body (IEA)

nucleoplasm (IDA)

nucleus (IDA)

Molecular Function

2 iron, 2 sulfur cluster binding (IEA)

arsenate reductase (glutaredoxin) activity (TAS)

electron transfer activity (NAS)

glutathione disulfide oxidoreductase activity (TAS)

metal ion binding (IEA)

protein binding (IPI)

protein disulfide isomerase activity (TAS)

protein disulfide oxidoreductase activity (IEA)

References

References - curated


1.	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8889549	PMID:9325327	PMID:10810093	PMID:11297543	PMID:11329013	PMID:11397793	PMID:12477932	PMID:14503974	PMID:14676218	PMID:14713336	PMID:15146197	PMID:15184054
PMID:15297967	PMID:15328416	PMID:15489334	PMID:15649413	PMID:15917333	PMID:16112873	PMID:16246122	PMID:16710414	PMID:16712839	PMID:17065220	PMID:17115894	PMID:17121859
PMID:17355958	PMID:17546662	PMID:17680760	PMID:17961515	PMID:18029348	PMID:18092940	PMID:18816065	PMID:19038292	PMID:19119916	PMID:19184988	PMID:19216714	PMID:19290777
PMID:19292455	PMID:19383853	PMID:19723146	PMID:20064440	PMID:20547138	PMID:20829229	PMID:20877624	PMID:20929858	PMID:21029046	PMID:21437321	PMID:21586322	PMID:21735102
PMID:22139372	PMID:23824909	PMID:24295294	PMID:25735211	PMID:26344197	PMID:27503909	PMID:28618115	PMID:29101900	PMID:29568061	PMID:31168542	PMID:32296183

Genomics

Comparative Map Data

GLRX2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	1	193,090,866 - 193,106,114 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	1	193,096,465 - 193,106,114 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	1	193,065,595 - 193,075,659 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	191,332,223 - 191,341,867 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	1	189,797,256 - 189,806,213	NCBI
Celera	1	166,175,205 - 166,184,851 (-)	NCBI
Cytogenetic Map	1	q31.2	NCBI
HuRef	1	164,301,400 - 164,311,051 (-)	NCBI		HuRef
CHM1_1	1	194,487,507 - 194,497,577 (-)	NCBI		CHM1_1

Glrx2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	143,614,787 - 143,625,416 (+)	NCBI	GRCm39		mm39
GRCm38	1	143,739,224 - 143,749,678 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	143,716,338 - 143,749,676 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	145,586,479 - 145,596,808 (+)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	1	145,501,567 - 145,511,896 (+)	NCBI			mm8
Celera	1	146,314,372 - 146,324,701 (+)	NCBI		Celera
Cytogenetic Map	1	F	NCBI
cM Map	1	62.53	NCBI

Glrx2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	13	60,529,057 - 60,552,115 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	60,529,932 - 60,537,916 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	65,517,621 - 65,540,676 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	57,567,017 - 57,589,873 (+)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	13	57,581,096 - 57,603,951 (+)	NCBI
Celera	13	55,569,577 - 55,592,422 (+)	NCBI		Celera
Cytogenetic Map	13	q21	NCBI

Glrx2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955406	30,497,562 - 30,509,340 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955406	30,497,562 - 30,506,463 (-)	NCBI	ChiLan1.0	ChiLan1.0

GLRX2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	1	172,848,858 - 172,859,970 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	172,849,013 - 172,859,062 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	1	168,555,858 - 168,565,949 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

GLRX2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	38	5,964,039 - 5,971,676 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	38	5,963,800 - 5,971,673 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Glrx2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936638	1,325,076 - 1,333,994 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GLRX2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	10	679,305 - 689,890 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

GLRX2
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	36,318,894 - 36,328,567 (+)	NCBI
ChlSab1.1 Ensembl	25	36,319,637 - 36,328,417 (+)	Ensembl

Glrx2
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624814	481,981 - 505,052 (+)	NCBI

Position Markers

SHGC-32745

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	1	193,066,754 - 193,066,888	UniSTS	GRCh37
Build 36	1	191,333,377 - 191,333,511	RGD	NCBI36
Celera	1	166,176,359 - 166,176,493	RGD
Cytogenetic Map	1	q31.2	UniSTS
HuRef	1	164,302,559 - 164,302,693	UniSTS
TNG Radiation Hybrid Map	1	93296.0	UniSTS
GeneMap99-GB4 RH Map	1	648.58	UniSTS
Whitehead-RH Map	1	809.2	UniSTS
NCBI RH Map	1	1596.8	UniSTS
GeneMap99-G3 RH Map	1	7508.0	UniSTS

SHGC-146669

Human Assembly	Chr	Position (strand)	Source	JBrowse
GRCh37	1	193,074,777 - 193,075,048	UniSTS	GRCh37
Build 36	1	191,341,400 - 191,341,671	RGD	NCBI36
Celera	1	166,184,382 - 166,184,653	RGD
Cytogenetic Map	1	q31.2	UniSTS
HuRef	1	164,310,582 - 164,310,853	UniSTS
TNG Radiation Hybrid Map	1	93284.0	UniSTS

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	125
Count of miRNA genes:	60
Interacting mature miRNAs:	60
Transcripts:	ENST00000367439, ENST00000367440, ENST00000472197
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system

circulatory system

endocrine system

exocrine system

hemolymphoid system

hepatobiliary system

integumental system

musculoskeletal system

nervous system

renal system

reproductive system

respiratory system

sensory system

adipose tissue

appendage

entire extraembryonic component

High

Medium

1130

1259

519

255

662

234

2244

1272

1267

205

968

588

658

1459

Low

1302

1710

1204

367

1274

230

2111

917

2441

212

482

1020

136

546

1329

Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NG_029745	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001243399	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_016066	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_197962	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AA056513	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AA887118	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF132495	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF151891	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF290514	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AL136370	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY038988	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC009669	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC028113	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BG182176	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BM887926	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BQ432881	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BU157087	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH471067	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CN362908	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DQ194815	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HB874295	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HB874309	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HB874850	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HB874864	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HB881206	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HB881220	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HB882353	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HB882367	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HB890952	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HB890966	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HB892776	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HB892790	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HB894074	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HB894088	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HB895424	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HB895438	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HB903255	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HB903269	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HC931704	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HC931718	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HC932259	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HC932273	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HC938615	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HC938629	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HC939762	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HC939776	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HC948361	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HC948375	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HC950185	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HC950199	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HC951483	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HC951497	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HC952833	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HC952847	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HC960664	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	HC960678	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENST00000367439 ⟹ ENSP00000356409

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	1	193,096,468 - 193,105,431 (-)	Ensembl

RefSeq Acc Id:

ENST00000367440 ⟹ ENSP00000356410

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	1	193,096,468 - 193,106,114 (-)	Ensembl

RefSeq Acc Id:

ENST00000472197

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	1	193,096,667 - 193,106,057 (-)	Ensembl

RefSeq Acc Id:

ENST00000608166 ⟹ ENSP00000494652

RefSeq Status:

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38.p13 Ensembl	1	193,090,866 - 193,105,433 (-)	Ensembl

RefSeq Acc Id:

NM_001243399 ⟹ NP_001230328

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	1	193,096,470 - 193,106,057 (-)	NCBI
GRCh37	1	193,065,595 - 193,075,659 (-)	NCBI
HuRef	1	164,301,400 - 164,311,051 (-)	NCBI
CHM1_1	1	194,487,507 - 194,497,099 (-)	NCBI

Sequence:

show sequence

ATTTCCAAAGCCATGGTGAAACATCTCTGTGCTAATTTCTTTTGTTTTGTTTCCTAATTTTTTT
TTTTTGGCAGGTGGTGGGAAATAATCTTTGTCTTCTTTGGAGTAAACCTTCAACACCGGATTTT
TTCTTTTAATTATGGATGTAAACCCCAATATCCCCATAATTTACATTGGGTCTCGACCAATTGC
CTAATTATAAGAGGATATATTTAGGCTCTTATTTCATCCACACAAAAACTTGTGTAACAGGTAG
TTGGAAACATCTGAGGCACCACTTTGATTCTGTTTTGGATGGTCATGTTTTTTCTCCTCCGTTT
CCCCAGCATGTCTGCCACCATCCTCATGCACTGCTTCCAAGTGCCTGGGAGCCTTTATGAGCGT
CCCTAAACCTAAAAGAATCCAGAGGCGGGGCTCGGATGAACCCTCGAGATAAGCAAGATGGAGA
GCAATACATCATCATCTTTGGAGAATTTAGCGACGGCGCCTGTGAACCAGATCCAAGAAACAAT
TTCTGATAATTGTGTGGTGATTTTCTCAAAAACATCCTGTTCTTACTGTACAATGGCAAAAAAG
CTTTTCCATGACATGAATGTTAACTATAAAGTGGTGGAACTGGACCTGCTTGAATATGGAAACC
AGTTCCAAGATGCTCTTTACAAAATGACTGGTGAAAGAACTGTTCCAAGAATATTTGTCAATGG
TACTTTTATTGGAGGTGCAACTGACACTCATAGGCTTCACAAAGAAGGAAAATTGCTCCCACTA
GTTCATCAGTGTTATTTAAAAAAAAGTAAGAGGAAAGAATTTCAGTGATGTTTATACTAATAAG
TTTGCTAGTACAGTGTCAGTTATTTAAAGTGGTAATGCCCGATAATGTCTTTTAAATGTTTGAG
GATGTTTTAAATACATGCATTGTCTTCACGAAGAAGATGTAAAAATAATGAACAATAAATTGCG
GTGGAAACCTCTTCTT

hide sequence

RefSeq Acc Id:

NM_016066 ⟹ NP_057150

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	1	193,096,465 - 193,106,114 (-)	NCBI
GRCh37	1	193,065,595 - 193,075,659 (-)	NCBI
Build 36	1	191,332,224 - 191,341,867 (-)	NCBI Archive
HuRef	1	164,301,400 - 164,311,051 (-)	NCBI
CHM1_1	1	194,487,507 - 194,497,156 (-)	NCBI

Sequence:

show sequence

AAGGCTATTATTACCACCACTGAGTGGCTTAAATAATCCTGTCAACAGCAATCGCCCATTTCCA
AAGCCATGGTGAAACATCTCTGTGCTAATTTCTTTTGTTTTGTTTCCTAATTTTTTTTTTTTGG
CAGGTGGTGGGAAATAATCTTTGTCTTCTTTGGAGTAAACCTTCAACACCGGATTTTTTCTTTT
AATTATGGATGTAAACCCCAATATCCCCATAATTTACATTGGGTCTCGACCAATTGCCTAATTA
TAAGAGGATATATTTAGGCTCTTATTTCATCCACACAAAAACTTGTGTAACAGGTAGTTGGAAA
CATCTGAGGCACCACTTTGATTCTGTTTTGGATGGTCATGTTTTTTCTCCTCCGTTTCCCCAGC
ATGTCTGCCACCATCCTCATGCACTGCTTCCAAGTGCCTGGGAGCCTTTATGAGCGTCCCTAAA
CCTAAAAGAATCCAGAGGCGGGGCTCGGATGAACCCTCGAGATAAGCAAGTGAGCCGCTTCTCC
CCTCTAAAGGATGTTTACACGTGGGTGGCACTCGCTGGAATCCAGCGCTCGGGCAGCCCTGGGA
GGACGCGCTCAGCTGCGAGGAGGATGGAGAGCAATACATCATCATCTTTGGAGAATTTAGCGAC
GGCGCCTGTGAACCAGATCCAAGAAACAATTTCTGATAATTGTGTGGTGATTTTCTCAAAAACA
TCCTGTTCTTACTGTACAATGGCAAAAAAGCTTTTCCATGACATGAATGTTAACTATAAAGTGG
TGGAACTGGACCTGCTTGAATATGGAAACCAGTTCCAAGATGCTCTTTACAAAATGACTGGTGA
AAGAACTGTTCCAAGAATATTTGTCAATGGTACTTTTATTGGAGGTGCAACTGACACTCATAGG
CTTCACAAAGAAGGAAAATTGCTCCCACTAGTTCATCAGTGTTATTTAAAAAAAAGTAAGAGGA
AAGAATTTCAGTGATGTTTATACTAATAAGTTTGCTAGTACAGTGTCAGTTATTTAAAGTGGTA
ATGCCCGATAATGTCTTTTAAATGTTTGAGGATGTTTTAAATACATGCATTGTCTTCACGAAGA
AGATGTAAAAATAATGAACAATAAATTGCGGTGGAAACCTCTTCTT

hide sequence

RefSeq Acc Id:

NM_197962 ⟹ NP_932066

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	1	193,096,470 - 193,105,414 (-)	NCBI
GRCh37	1	193,065,595 - 193,075,659 (-)	NCBI
Build 36	1	191,332,223 - 191,341,179 (-)	NCBI Archive
HuRef	1	164,301,400 - 164,311,051 (-)	NCBI
CHM1_1	1	194,487,507 - 194,496,520 (-)	NCBI

Sequence:

show sequence

CGGGGCGGGGCAAGGCGGGGGCCGGGCCGGAGGAGGCGGGCTCCCGGGATCCGCGGTGTCCGGC
AGTAGAGCTCGCTGCAGATCCGGGCTCTGACCATGATTTGGCGCCGCGCGGCGCTGGCGGGGAC
GCGGCTGGTTTGGAGCAGGAGCGGCTCGGCAGGCTGGCTTGACAGGGCGGCGGGAGCTGCGGGA
GCTGCGGCAGCTGCGGCCTCTGGGATGGAGAGCAATACATCATCATCTTTGGAGAATTTAGCGA
CGGCGCCTGTGAACCAGATCCAAGAAACAATTTCTGATAATTGTGTGGTGATTTTCTCAAAAAC
ATCCTGTTCTTACTGTACAATGGCAAAAAAGCTTTTCCATGACATGAATGTTAACTATAAAGTG
GTGGAACTGGACCTGCTTGAATATGGAAACCAGTTCCAAGATGCTCTTTACAAAATGACTGGTG
AAAGAACTGTTCCAAGAATATTTGTCAATGGTACTTTTATTGGAGGTGCAACTGACACTCATAG
GCTTCACAAAGAAGGAAAATTGCTCCCACTAGTTCATCAGTGTTATTTAAAAAAAAGTAAGAGG
AAAGAATTTCAGTGATGTTTATACTAATAAGTTTGCTAGTACAGTGTCAGTTATTTAAAGTGGT
AATGCCCGATAATGTCTTTTAAATGTTTGAGGATGTTTTAAATACATGCATTGTCTTCACGAAG
AAGATGTAAAAATAATGAACAATAAATTGCGGTGGAAACCTCTTCTT

hide sequence

Protein Sequences


Protein RefSeqs	NP_001230328	(Get FASTA)	NCBI Sequence Viewer
	NP_057150	(Get FASTA)	NCBI Sequence Viewer
	NP_932066	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAD34128	(Get FASTA)	NCBI Sequence Viewer
	AAF37320	(Get FASTA)	NCBI Sequence Viewer
	AAH09669	(Get FASTA)	NCBI Sequence Viewer
	AAH28113	(Get FASTA)	NCBI Sequence Viewer
	AAK72499	(Get FASTA)	NCBI Sequence Viewer
	AAK83089	(Get FASTA)	NCBI Sequence Viewer
	ABA03170	(Get FASTA)	NCBI Sequence Viewer
	CBF61391	(Get FASTA)	NCBI Sequence Viewer
	CBF61398	(Get FASTA)	NCBI Sequence Viewer
	CBF61800	(Get FASTA)	NCBI Sequence Viewer
	CBF61807	(Get FASTA)	NCBI Sequence Viewer
	CBF64885	(Get FASTA)	NCBI Sequence Viewer
	CBF64892	(Get FASTA)	NCBI Sequence Viewer
	CBF65449	(Get FASTA)	NCBI Sequence Viewer
	CBF65456	(Get FASTA)	NCBI Sequence Viewer
	CBF69768	(Get FASTA)	NCBI Sequence Viewer
	CBF69783	(Get FASTA)	NCBI Sequence Viewer
	CBF71621	(Get FASTA)	NCBI Sequence Viewer
	CBF71635	(Get FASTA)	NCBI Sequence Viewer
	CBF72937	(Get FASTA)	NCBI Sequence Viewer
	CBF72952	(Get FASTA)	NCBI Sequence Viewer
	CBF74264	(Get FASTA)	NCBI Sequence Viewer
	CBF74280	(Get FASTA)	NCBI Sequence Viewer
	CBF82314	(Get FASTA)	NCBI Sequence Viewer
	CBF82330	(Get FASTA)	NCBI Sequence Viewer
	CBU86419	(Get FASTA)	NCBI Sequence Viewer
	CBU86426	(Get FASTA)	NCBI Sequence Viewer
	CBU86676	(Get FASTA)	NCBI Sequence Viewer
	CBU86683	(Get FASTA)	NCBI Sequence Viewer
	CBU89756	(Get FASTA)	NCBI Sequence Viewer
	CBU89763	(Get FASTA)	NCBI Sequence Viewer
	CBU90320	(Get FASTA)	NCBI Sequence Viewer
	CBU90327	(Get FASTA)	NCBI Sequence Viewer
	CBU94419	(Get FASTA)	NCBI Sequence Viewer
	CBU94426	(Get FASTA)	NCBI Sequence Viewer
	CBU95298	(Get FASTA)	NCBI Sequence Viewer
	CBU95305	(Get FASTA)	NCBI Sequence Viewer
	CBU95927	(Get FASTA)	NCBI Sequence Viewer
	CBU95934	(Get FASTA)	NCBI Sequence Viewer
	CBU96576	(Get FASTA)	NCBI Sequence Viewer
	CBU96583	(Get FASTA)	NCBI Sequence Viewer
	CBV00324	(Get FASTA)	NCBI Sequence Viewer
	CBV00331	(Get FASTA)	NCBI Sequence Viewer
	EAW91248	(Get FASTA)	NCBI Sequence Viewer
	EAW91249	(Get FASTA)	NCBI Sequence Viewer
	Q9NS18	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_932066 ⟸ NM_197962
- Peptide Label:	isoform 2 precursor
- UniProtKB:	Q9NS18 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MIWRRAALAGTRLVWSRSGSAGWLDRAAGAAGAAAAAASGMESNTSSSLENLATAPVNQIQETI SDNCVVIFSKTSCSYCTMAKKLFHDMNVNYKVVELDLLEYGNQFQDALYKMTGERTVPRIFVNG TFIGGATDTHRLHKEGKLLPLVHQCYLKKSKRKEFQ hide sequence

RefSeq Acc Id:	NP_057150 ⟸ NM_016066
- Peptide Label:	isoform 1
- UniProtKB:	Q9NS18 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MNPRDKQVSRFSPLKDVYTWVALAGIQRSGSPGRTRSAARRMESNTSSSLENLATAPVNQIQET ISDNCVVIFSKTSCSYCTMAKKLFHDMNVNYKVVELDLLEYGNQFQDALYKMTGERTVPRIFVN GTFIGGATDTHRLHKEGKLLPLVHQCYLKKSKRKEFQ hide sequence

RefSeq Acc Id:	NP_001230328 ⟸ NM_001243399
- Peptide Label:	isoform 3
- UniProtKB:	Q9NS18 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MESNTSSSLENLATAPVNQIQETISDNCVVIFSKTSCSYCTMAKKLFHDMNVNYKVVELDLLEY GNQFQDALYKMTGERTVPRIFVNGTFIGGATDTHRLHKEGKLLPLVHQCYLKKSKRKEFQ hide sequence

RefSeq Acc Id:

ENSP00000356410 ⟸ ENST00000367440

RefSeq Acc Id:

ENSP00000356409 ⟸ ENST00000367439

RefSeq Acc Id:

ENSP00000494652 ⟸ ENST00000608166

Protein Domains

Glutaredoxin

Promoters

RGD ID:

6785647

Promoter ID:

HG_KWN:6633

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

CD4+TCell_12Hour, CD4+TCell_2Hour, HeLa_S3, K562, Lymphoblastoid, NB4

Transcripts:

OTTHUMT00000086699, OTTHUMT00000086700, OTTHUMT00000086701

Position:

Human Assembly	Chr	Position (strand)	Source
Build 36	1	191,340,921 - 191,341,421 (-)	MPROMDB

RGD ID:

6858440

Promoter ID:

EPDNEW_H2385

Type:

initiation region

Name:

GLRX2_1

Description:

glutaredoxin 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_H2386 EPDNEW_H2387

Experiment Methods:

Single-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	1	193,105,414 - 193,105,474	EPDNEW

RGD ID:

6858442

Promoter ID:

EPDNEW_H2386

Type:

multiple initiation site

Name:

GLRX2_2

Description:

glutaredoxin 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_H2385 EPDNEW_H2387

Experiment Methods:

Single-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	1	193,106,052 - 193,106,112	EPDNEW

RGD ID:

6858444

Promoter ID:

EPDNEW_H2387

Type:

initiation region

Name:

GLRX2_3

Description:

glutaredoxin 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Alternative Promoters:

null; see alsoEPDNEW_H2385 EPDNEW_H2386

Experiment Methods:

Single-end sequencing.; Paired-end sequencing.

Position:

Human Assembly	Chr	Position (strand)	Source
GRCh38	1	193,115,708 - 193,115,768	EPDNEW

Clinical Variants

Name	Type	Condition(s)	Position(s)	Clinical significance
GRCh38/hg38 1q31.1-42.11(chr1:187143981-224299417)x3	copy number gain	See cases [RCV000051857]	Chr1:187143981..224299417 [GRCh38] Chr1:187113113..224487119 [GRCh37] Chr1:185379736..222553742 [NCBI36] Chr1:1q31.1-42.11	pathogenic
GRCh38/hg38 1q25.2-32.1(chr1:179032905-199724897)x1	copy number loss	See cases [RCV000053948]	Chr1:179032905..199724897 [GRCh38] Chr1:179002040..199694025 [GRCh37] Chr1:177268663..197960648 [NCBI36] Chr1:1q25.2-32.1	pathogenic
GRCh38/hg38 1q31.2(chr1:192567876-193180049)x1	copy number loss	See cases [RCV000053950]	Chr1:192567876..193180049 [GRCh38] Chr1:192537006..193149179 [GRCh37] Chr1:190803629..191415802 [NCBI36] Chr1:1q31.2	pathogenic
GRCh38/hg38 1q25.2-31.3(chr1:176595962-196301688)x1	copy number loss	See cases [RCV000134144]	Chr1:176595962..196301688 [GRCh38] Chr1:176565098..196270818 [GRCh37] Chr1:174831721..194537441 [NCBI36] Chr1:1q25.2-31.3	pathogenic
GRCh38/hg38 1q31.1-32.1(chr1:189034483-199615866)x1	copy number loss	See cases [RCV000135590]	Chr1:189034483..199615866 [GRCh38] Chr1:189003614..199584994 [GRCh37] Chr1:187270237..197851617 [NCBI36] Chr1:1q31.1-32.1	pathogenic
Single allele	deletion	Hyperparathyroidism 1 [RCV000677958]	Chr1:191919194..194615758 [GRCh38] Chr1:191888324..194584888 [GRCh37] Chr1:1q31.2-31.3	pathogenic
GRCh37/hg19 1q25.2-32.1(chr1:179413479-201764737)x1	copy number loss	See cases [RCV000445748]	Chr1:179413479..201764737 [GRCh37] Chr1:1q25.2-32.1	pathogenic
GRCh37/hg19 1q25.2-32.1(chr1:179073386-200192265)x1	copy number loss	See cases [RCV000448809]	Chr1:179073386..200192265 [GRCh37] Chr1:1q25.2-32.1	pathogenic
GRCh37/hg19 1q24.3-31.3(chr1:171990029-195086758)x1	copy number loss	See cases [RCV000448686]	Chr1:171990029..195086758 [GRCh37] Chr1:1q24.3-31.3	pathogenic
GRCh37/hg19 1q25.2-32.1(chr1:179011314-199022759)x1	copy number loss	See cases [RCV000512128]	Chr1:179011314..199022759 [GRCh37] Chr1:1q25.2-32.1	pathogenic
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684)x3	copy number gain	See cases [RCV000510383]	Chr1:849467..249224684 [GRCh37] Chr1:1p36.33-q44	pathogenic
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684)	copy number gain	See cases [RCV000510926]	Chr1:849467..249224684 [GRCh37] Chr1:1p36.33-q44	pathogenic
GRCh37/hg19 1p36.33-q44(chr1:47851-249228449)x3	copy number gain	not provided [RCV000736295]	Chr1:47851..249228449 [GRCh37] Chr1:1p36.33-q44	pathogenic
GRCh37/hg19 1p36.33-q44(chr1:82154-249218992)x3	copy number gain	not provided [RCV000736305]	Chr1:82154..249218992 [GRCh37] Chr1:1p36.33-q44	pathogenic
GRCh37/hg19 1q25.3-41(chr1:185644663-221698833)x3	copy number gain	not provided [RCV000749265]	Chr1:185644663..221698833 [GRCh37] Chr1:1q25.3-41	pathogenic
GRCh37/hg19 1q25.3-44(chr1:182388773-249111240)x3	copy number gain	not provided [RCV000845852]	Chr1:182388773..249111240 [GRCh37] Chr1:1q25.3-44	pathogenic
GRCh37/hg19 1q25.2-32.1(chr1:177551193-199599056)x1	copy number loss	not provided [RCV001005157]	Chr1:177551193..199599056 [GRCh37] Chr1:1q25.2-32.1	pathogenic

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	HGNC:16065	AgrOrtholog
COSMIC	GLRX2	COSMIC
Ensembl Genes	ENSG00000023572	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein	ENSP00000356409	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSP00000356410	ENTREZGENE, UniProtKB/Swiss-Prot
	ENSP00000494652	UniProtKB/Swiss-Prot
Ensembl Transcript	ENST00000367439	ENTREZGENE, UniProtKB/Swiss-Prot
	ENST00000367440	ENTREZGENE, UniProtKB/Swiss-Prot
	ENST00000608166	UniProtKB/Swiss-Prot
Gene3D-CATH	3.40.30.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx	ENSG00000023572	GTEx
HGNC ID	HGNC:16065	ENTREZGENE
Human Proteome Map	GLRX2	Human Proteome Map
InterPro	Glutaredoxin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Glutaredoxin_euk/vir	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Glutaredoxin_subgr	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Thioredoxin-like_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	hsa:51022	UniProtKB/Swiss-Prot
NCBI Gene	51022	ENTREZGENE
OMIM	606820	OMIM
Pfam	Glutaredoxin	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB	PA28732	PharmGKB
PRINTS	GLUTAREDOXIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	GLUTAREDOXIN_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF52833	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGRFAMs	GRX_euk	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene	Hs.458283	ENTREZGENE
UniProt	A0JLT0_HUMAN	UniProtKB/TrEMBL
	GLRX2_HUMAN	UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary	Q3LR69	UniProtKB/Swiss-Prot
	Q7L1N7	UniProtKB/Swiss-Prot
	Q96JC0	UniProtKB/Swiss-Prot
	Q9Y3D4	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar