ZC3H15 (zinc finger CCCH-type containing 15) - Rat Genome Database

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Gene: ZC3H15 (zinc finger CCCH-type containing 15) Homo sapiens
Analyze
Symbol: ZC3H15
Name: zinc finger CCCH-type containing 15
RGD ID: 1601751
HGNC Page HGNC:29528
Description: Enables RNA binding activity and cadherin binding activity. Involved in positive regulation of GTPase activity. Located in cytosol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DFRP1; DRG family-regulatory protein 1; HT010; LEREPO4; likely ortholog of mouse immediate early response erythropoietin 4; MSTP012; zinc finger CCCH domain-containing protein 15
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382186,486,260 - 186,509,361 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2186,486,253 - 186,511,929 (+)EnsemblGRCh38hg38GRCh38
GRCh372187,350,987 - 187,374,088 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362187,059,130 - 187,082,333 (+)NCBINCBI36Build 36hg18NCBI36
Celera2180,946,684 - 180,969,891 (+)NCBICelera
Cytogenetic Map2q32.1NCBI
HuRef2179,210,476 - 179,234,063 (+)NCBIHuRef
CHM1_12187,357,183 - 187,380,391 (+)NCBICHM1_1
T2T-CHM13v2.02186,975,546 - 186,998,651 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IEA)
cytosol  (IBA,IDA,TAS)
nucleus  (IEA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10880228   PMID:12477932   PMID:14702039   PMID:15676025   PMID:16009940   PMID:17207965   PMID:18029348   PMID:19274049   PMID:19490893   PMID:19819225   PMID:20925576   PMID:21516116  
PMID:21873635   PMID:21900206   PMID:22113938   PMID:22658674   PMID:22681889   PMID:22939629   PMID:23125841   PMID:23455922   PMID:23624947   PMID:23711155   PMID:24244333   PMID:24457600  
PMID:25281560   PMID:25416956   PMID:25468996   PMID:25921289   PMID:26186194   PMID:26344197   PMID:26496610   PMID:26638075   PMID:26673895   PMID:27049334   PMID:27142060   PMID:27191988  
PMID:28416769   PMID:28514442   PMID:28515276   PMID:28712289   PMID:29229926   PMID:29509190   PMID:29568061   PMID:29802200   PMID:29845934   PMID:29872149   PMID:30631154   PMID:30884312  
PMID:30940648   PMID:30948266   PMID:31059266   PMID:31091453   PMID:31527615   PMID:31665637   PMID:31753913   PMID:32129710   PMID:32296183   PMID:32457219   PMID:32687490   PMID:32707033  
PMID:32788342   PMID:32807901   PMID:32838362   PMID:32994395   PMID:33022573   PMID:33306668   PMID:33397691   PMID:33545068   PMID:33916271   PMID:33957083   PMID:33961781   PMID:34029587  
PMID:34079125   PMID:34189442   PMID:34349018   PMID:34591612   PMID:34597346   PMID:34709727   PMID:34988227   PMID:35013218   PMID:35027542   PMID:35256949   PMID:35271311   PMID:35439318  
PMID:35509820   PMID:35563538   PMID:35652658   PMID:35831314   PMID:35944360   PMID:36057605   PMID:36114006   PMID:36215168   PMID:36232890   PMID:36373674   PMID:36526897   PMID:37314180  
PMID:37774976   PMID:38113892   PMID:38697112   PMID:38891874   PMID:39231216  


Genomics

Comparative Map Data
ZC3H15
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382186,486,260 - 186,509,361 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2186,486,253 - 186,511,929 (+)EnsemblGRCh38hg38GRCh38
GRCh372187,350,987 - 187,374,088 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362187,059,130 - 187,082,333 (+)NCBINCBI36Build 36hg18NCBI36
Celera2180,946,684 - 180,969,891 (+)NCBICelera
Cytogenetic Map2q32.1NCBI
HuRef2179,210,476 - 179,234,063 (+)NCBIHuRef
CHM1_12187,357,183 - 187,380,391 (+)NCBICHM1_1
T2T-CHM13v2.02186,975,546 - 186,998,651 (+)NCBIT2T-CHM13v2.0
Zc3h15
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39283,474,922 - 83,494,961 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl283,474,779 - 83,494,966 (+)EnsemblGRCm39 Ensembl
GRCm38283,644,578 - 83,664,617 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl283,644,435 - 83,664,622 (+)EnsemblGRCm38mm10GRCm38
MGSCv37283,484,735 - 83,504,774 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36283,445,417 - 83,465,456 (+)NCBIMGSCv36mm8
Celera285,284,428 - 85,304,248 (+)NCBICelera
Cytogenetic Map2DNCBI
cM Map249.33NCBI
Zc3h15
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8389,151,432 - 89,171,203 (+)NCBIGRCr8
mRatBN7.2368,744,591 - 68,764,335 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl368,744,604 - 68,764,333 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx372,147,117 - 72,166,722 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0380,745,773 - 80,765,378 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0378,480,214 - 78,499,776 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0371,020,420 - 71,040,159 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl371,020,534 - 71,040,157 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0377,550,822 - 77,570,544 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4366,821,085 - 66,840,710 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1366,717,456 - 66,737,080 (+)NCBI
Celera368,123,487 - 68,143,111 (+)NCBICelera
Cytogenetic Map3q24NCBI
Zc3h15
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540311,740,107 - 11,761,005 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540311,740,107 - 11,761,005 (-)NCBIChiLan1.0ChiLan1.0
ZC3H15
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21389,161,727 - 89,185,225 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B89,176,974 - 89,200,205 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B73,774,955 - 73,798,061 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B191,576,403 - 191,599,609 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B191,576,403 - 191,599,609 (+)Ensemblpanpan1.1panPan2
ZC3H15
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13628,730,213 - 28,743,884 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3628,725,079 - 28,743,884 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3628,627,635 - 28,641,296 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03628,950,239 - 29,009,303 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3628,949,771 - 28,969,725 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13629,014,656 - 29,028,335 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03628,946,032 - 28,959,704 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03629,116,356 - 29,130,029 (+)NCBIUU_Cfam_GSD_1.0
Zc3h15
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303145,903,340 - 145,929,725 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493650610,907,697 - 10,934,785 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493650610,908,347 - 10,934,785 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZC3H15
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1591,493,713 - 91,518,760 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11591,493,591 - 91,517,362 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215101,503,541 - 101,527,322 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ZC3H15
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11072,020,594 - 72,044,050 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1072,020,808 - 72,043,420 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040127,461,984 - 127,485,862 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Zc3h15
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248993,394,009 - 3,415,446 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ZC3H15
13 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 2q31.1-33.2(chr2:174898848-203941548)x1 copy number loss See cases [RCV000050980] Chr2:174898848..203941548 [GRCh38]
Chr2:175763576..204806271 [GRCh37]
Chr2:175471822..204514516 [NCBI36]
Chr2:2q31.1-33.2		 pathogenic
GRCh38/hg38 2q31.1-33.1(chr2:176304445-202039790)x1 copy number loss See cases [RCV000052558] Chr2:176304445..202039790 [GRCh38]
Chr2:177169173..202904513 [GRCh37]
Chr2:176877419..202612758 [NCBI36]
Chr2:2q31.1-33.1		 pathogenic
GRCh38/hg38 2q31.2-33.1(chr2:177874070-198525492)x1 copy number loss See cases [RCV000052559] Chr2:177874070..198525492 [GRCh38]
Chr2:178738797..199390216 [GRCh37]
Chr2:178447043..199098461 [NCBI36]
Chr2:2q31.2-33.1		 pathogenic
NM_018471.2(ZC3H15):c.513G>A (p.Lys171=) single nucleotide variant Malignant melanoma [RCV000060425] Chr2:186502566 [GRCh38]
Chr2:187367293 [GRCh37]
Chr2:187075538 [NCBI36]
Chr2:2q32.1		 not provided
GRCh38/hg38 2q32.1-33.1(chr2:186027472-201059372)x1 copy number loss See cases [RCV000135876] Chr2:186027472..201059372 [GRCh38]
Chr2:186892199..201924095 [GRCh37]
Chr2:186600444..201632340 [NCBI36]
Chr2:2q32.1-33.1		 pathogenic
GRCh38/hg38 2q31.1-32.2(chr2:171429233-189179568)x1 copy number loss See cases [RCV000136850] Chr2:171429233..189179568 [GRCh38]
Chr2:172285743..190044294 [GRCh37]
Chr2:171993989..189752539 [NCBI36]
Chr2:2q31.1-32.2		 pathogenic
GRCh38/hg38 2q31.1-32.2(chr2:174634502-189000964)x1 copy number loss See cases [RCV000136861] Chr2:174634502..189000964 [GRCh38]
Chr2:175499230..189865690 [GRCh37]
Chr2:175207476..189573935 [NCBI36]
Chr2:2q31.1-32.2		 pathogenic
GRCh38/hg38 2q31.3-32.1(chr2:180942902-187372388)x1 copy number loss See cases [RCV000137116] Chr2:180942902..187372388 [GRCh38]
Chr2:181807629..188237115 [GRCh37]
Chr2:181515874..187945360 [NCBI36]
Chr2:2q31.3-32.1		 pathogenic
GRCh38/hg38 2q31.3-32.3(chr2:181758701-192015392)x1 copy number loss See cases [RCV000138253] Chr2:181758701..192015392 [GRCh38]
Chr2:182623428..192880118 [GRCh37]
Chr2:182331673..192588363 [NCBI36]
Chr2:2q31.3-32.3		 pathogenic
GRCh38/hg38 2q31.3-36.2(chr2:180513793-224302848)x3 copy number gain See cases [RCV000139446] Chr2:180513793..224302848 [GRCh38]
Chr2:181378520..225167565 [GRCh37]
Chr2:181086765..224875809 [NCBI36]
Chr2:2q31.3-36.2		 pathogenic
GRCh38/hg38 2q31.2-32.3(chr2:177827730-195125329)x1 copy number loss See cases [RCV000141735] Chr2:177827730..195125329 [GRCh38]
Chr2:178692457..195990053 [GRCh37]
Chr2:178400703..195698298 [NCBI36]
Chr2:2q31.2-32.3		 pathogenic
GRCh38/hg38 2q31.1-32.3(chr2:176086763-193201970)x1 copy number loss See cases [RCV000143484] Chr2:176086763..193201970 [GRCh38]
Chr2:176951491..194066696 [GRCh37]
Chr2:176659737..193774941 [NCBI36]
Chr2:2q31.1-32.3		 pathogenic
GRCh37/hg19 2q31.1-32.3(chr2:177315153-196375520)x1 copy number loss See cases [RCV000239432] Chr2:177315153..196375520 [GRCh37]
Chr2:2q31.1-32.3		 pathogenic
GRCh37/hg19 2q31.1-35(chr2:169829974-215521436)x3 copy number gain See cases [RCV000448271] Chr2:169829974..215521436 [GRCh37]
Chr2:2q31.1-35		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:12771-242783384) copy number gain See cases [RCV000512056] Chr2:12771..242783384 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:12771-242783384)x3 copy number gain See cases [RCV000511212] Chr2:12771..242783384 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:14238-243048760)x3 copy number gain not provided [RCV000752802] Chr2:14238..243048760 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:15672-243101834)x3 copy number gain not provided [RCV000752804] Chr2:15672..243101834 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2q32.1(chr2:187370142-188535099)x4 copy number gain not provided [RCV000740779] Chr2:187370142..188535099 [GRCh37]
Chr2:2q32.1		 uncertain significance
GRCh37/hg19 2q31.1-32.3(chr2:174690039-195521582)x1 copy number loss not provided [RCV001005359] Chr2:174690039..195521582 [GRCh37]
Chr2:2q31.1-32.3		 pathogenic
Single allele deletion Neurodevelopmental disorder [RCV000787402] Chr2:186356601..188906835 [GRCh37]
Chr2:2q32.1		 pathogenic
GRCh37/hg19 2q32.1(chr2:186861444-188658263)x1 copy number loss not provided [RCV000845864] Chr2:186861444..188658263 [GRCh37]
Chr2:2q32.1		 uncertain significance
GRCh37/hg19 2q24.3-32.3(chr2:167329586-192756373)x1 copy number loss not provided [RCV000848216] Chr2:167329586..192756373 [GRCh37]
Chr2:2q24.3-32.3		 pathogenic
GRCh37/hg19 2q24.2-34(chr2:163233162-211927188)x3 copy number gain not provided [RCV001005349] Chr2:163233162..211927188 [GRCh37]
Chr2:2q24.2-34		 pathogenic
GRCh37/hg19 2q32.1(chr2:186234826-188972311)x3 copy number gain not provided [RCV000847709] Chr2:186234826..188972311 [GRCh37]
Chr2:2q32.1		 uncertain significance
GRCh37/hg19 2q32.1(chr2:183764930-187399282)x1 copy number loss not provided [RCV001249408] Chr2:183764930..187399282 [GRCh37]
Chr2:2q32.1		 not provided
GRCh37/hg19 2q32.1-34(chr2:185697659-213002074) copy number loss Chromosome 2q32-q33 deletion syndrome [RCV002280608] Chr2:185697659..213002074 [GRCh37]
Chr2:2q32.1-34		 pathogenic
GRCh37/hg19 2q31.2-37.3(chr2:178397959-243007457)x3 copy number gain See cases [RCV001263052] Chr2:178397959..243007457 [GRCh37]
Chr2:2q31.2-37.3		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:1-243199373) copy number gain Mosaic trisomy 2 [RCV002280628] Chr2:1..243199373 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
NM_018471.3(ZC3H15):c.1012A>C (p.Ile338Leu) single nucleotide variant not specified [RCV004686082] Chr2:186506758 [GRCh38]
Chr2:187371485 [GRCh37]
Chr2:2q32.1		 uncertain significance
GRCh37/hg19 2q31.1-35(chr2:169829974-215521436) copy number gain not specified [RCV002053265] Chr2:169829974..215521436 [GRCh37]
Chr2:2q31.1-35		 pathogenic
GRCh37/hg19 2q32.1-33.1(chr2:187152754-199960525)x1 copy number loss not provided [RCV002472632] Chr2:187152754..199960525 [GRCh37]
Chr2:2q32.1-33.1		 pathogenic
NM_018471.3(ZC3H15):c.893G>A (p.Arg298His) single nucleotide variant not specified [RCV004092560] Chr2:186505768 [GRCh38]
Chr2:187370495 [GRCh37]
Chr2:2q32.1		 uncertain significance
NM_018471.3(ZC3H15):c.439A>G (p.Lys147Glu) single nucleotide variant not specified [RCV004079402] Chr2:186501422 [GRCh38]
Chr2:187366149 [GRCh37]
Chr2:2q32.1		 uncertain significance
NM_018471.3(ZC3H15):c.351T>G (p.Asp117Glu) single nucleotide variant not specified [RCV004127842] Chr2:186501334 [GRCh38]
Chr2:187366061 [GRCh37]
Chr2:2q32.1		 uncertain significance
NM_018471.3(ZC3H15):c.169C>G (p.Pro57Ala) single nucleotide variant not specified [RCV004218243] Chr2:186495326 [GRCh38]
Chr2:187360053 [GRCh37]
Chr2:2q32.1		 uncertain significance
NM_018471.3(ZC3H15):c.847G>A (p.Ala283Thr) single nucleotide variant not specified [RCV004175703] Chr2:186505580 [GRCh38]
Chr2:187370307 [GRCh37]
Chr2:2q32.1		 uncertain significance
NM_018471.3(ZC3H15):c.131A>G (p.Lys44Arg) single nucleotide variant not specified [RCV004245140] Chr2:186495288 [GRCh38]
Chr2:187360015 [GRCh37]
Chr2:2q32.1		 uncertain significance
NM_018471.3(ZC3H15):c.646G>T (p.Val216Leu) single nucleotide variant not specified [RCV004199070] Chr2:186504143 [GRCh38]
Chr2:187368870 [GRCh37]
Chr2:2q32.1		 uncertain significance
NM_018471.3(ZC3H15):c.637C>G (p.Pro213Ala) single nucleotide variant not specified [RCV004187589] Chr2:186504134 [GRCh38]
Chr2:187368861 [GRCh37]
Chr2:2q32.1		 uncertain significance
GRCh37/hg19 2q32.1-36.1(chr2:186698504-223918111)x3 copy number gain See cases [RCV003329558] Chr2:186698504..223918111 [GRCh37]
Chr2:2q32.1-36.1		 pathogenic
GRCh37/hg19 2q32.1(chr2:186712840-187407719)x3 copy number gain not provided [RCV003484081] Chr2:186712840..187407719 [GRCh37]
Chr2:2q32.1		 uncertain significance
NM_018471.3(ZC3H15):c.1162G>A (p.Glu388Lys) single nucleotide variant not specified [RCV004481265] Chr2:186508614 [GRCh38]
Chr2:187373341 [GRCh37]
Chr2:2q32.1		 uncertain significance
NM_018471.3(ZC3H15):c.1175C>T (p.Thr392Met) single nucleotide variant not specified [RCV004481266] Chr2:186508627 [GRCh38]
Chr2:187373354 [GRCh37]
Chr2:2q32.1		 uncertain significance
NM_018471.3(ZC3H15):c.1234T>A (p.Leu412Met) single nucleotide variant not specified [RCV004481267] Chr2:186508686 [GRCh38]
Chr2:187373413 [GRCh37]
Chr2:2q32.1		 uncertain significance
NM_018471.3(ZC3H15):c.660T>A (p.Asp220Glu) single nucleotide variant not specified [RCV004481268] Chr2:186504157 [GRCh38]
Chr2:187368884 [GRCh37]
Chr2:2q32.1		 uncertain significance
NM_018471.3(ZC3H15):c.950G>A (p.Gly317Glu) single nucleotide variant not specified [RCV004686081] Chr2:186505825 [GRCh38]
Chr2:187370552 [GRCh37]
Chr2:2q32.1		 uncertain significance
NM_018471.3(ZC3H15):c.1062A>T (p.Arg354Ser) single nucleotide variant not specified [RCV004686083] Chr2:186506808 [GRCh38]
Chr2:187371535 [GRCh37]
Chr2:2q32.1		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1542
Count of miRNA genes:643
Interacting mature miRNAs:759
Transcripts:ENST00000337859, ENST00000421536, ENST00000437396, ENST00000445547, ENST00000468120, ENST00000477672, ENST00000481101, ENST00000496289, ENST00000498757, ENST00000544130
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH121216  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372187,349,155 - 187,349,442UniSTSGRCh37
Build 362187,057,400 - 187,057,687RGDNCBI36
Celera2180,944,954 - 180,945,241RGD
Cytogenetic Map2q32.1UniSTS
HuRef2179,208,747 - 179,209,034UniSTS
TNG Radiation Hybrid Map2103255.0UniSTS
RH70209  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372187,368,614 - 187,368,782UniSTSGRCh37
Build 362187,076,859 - 187,077,027RGDNCBI36
Celera2180,964,416 - 180,964,584RGD
Cytogenetic Map2q32.1UniSTS
HuRef2179,228,588 - 179,228,756UniSTS
GeneMap99-GB4 RH Map2593.65UniSTS
A009S24  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372187,368,677 - 187,368,803UniSTSGRCh37
Build 362187,076,922 - 187,077,048RGDNCBI36
Celera2180,964,479 - 180,964,605RGD
Cytogenetic Map2q32.1UniSTS
HuRef2179,228,651 - 179,228,777UniSTS
GeneMap99-GB4 RH Map2593.65UniSTS
T16069  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372187,373,702 - 187,374,013UniSTSGRCh37
Build 362187,081,947 - 187,082,258RGDNCBI36
Celera2180,969,505 - 180,969,816RGD
Cytogenetic Map2q32.1UniSTS
HuRef2179,233,677 - 179,233,988UniSTS
Whitehead-YAC Contig Map2 UniSTS
G32811  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372187,368,677 - 187,368,803UniSTSGRCh37
Celera2180,964,479 - 180,964,605UniSTS
Cytogenetic Map2q32.1UniSTS
HuRef2179,228,651 - 179,228,777UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2439 2788 2253 4974 1726 2351 6 624 1951 465 2270 7306 6472 53 3734 1 852 1744 1617 175 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_018471 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017004502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC018867 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF109366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF147724 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF161421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF220184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF289586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF462448 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK001901 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK297658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK298615 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL040058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL049948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC012336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC021102 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000337859   ⟹   ENSP00000338788
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2186,486,260 - 186,509,361 (+)Ensembl
Ensembl Acc Id: ENST00000421536   ⟹   ENSP00000410981
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2186,486,253 - 186,506,091 (+)Ensembl
Ensembl Acc Id: ENST00000437396   ⟹   ENSP00000407192
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2186,486,263 - 186,501,375 (+)Ensembl
Ensembl Acc Id: ENST00000445547   ⟹   ENSP00000415788
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2186,506,713 - 186,509,114 (+)Ensembl
Ensembl Acc Id: ENST00000468120
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2186,486,918 - 186,504,099 (+)Ensembl
Ensembl Acc Id: ENST00000477672
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2186,486,267 - 186,495,319 (+)Ensembl
Ensembl Acc Id: ENST00000481101
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2186,486,891 - 186,504,086 (+)Ensembl
Ensembl Acc Id: ENST00000496289
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2186,487,270 - 186,504,070 (+)Ensembl
Ensembl Acc Id: ENST00000498757
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2186,505,091 - 186,508,690 (+)Ensembl
Ensembl Acc Id: ENST00000718440   ⟹   ENSP00000520825
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2186,486,260 - 186,511,929 (+)Ensembl
RefSeq Acc Id: NM_018471   ⟹   NP_060941
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382186,486,260 - 186,509,361 (+)NCBI
GRCh372187,350,885 - 187,374,088 (+)RGD
Build 362187,059,130 - 187,082,333 (+)NCBI Archive
Celera2180,946,684 - 180,969,891 (+)RGD
HuRef2179,210,476 - 179,234,063 (+)RGD
CHM1_12187,357,183 - 187,380,391 (+)NCBI
T2T-CHM13v2.02186,975,546 - 186,998,651 (+)NCBI
Sequence:
RefSeq Acc Id: NP_060941   ⟸   NM_018471
- UniProtKB: Q9NZ37 (UniProtKB/Swiss-Prot),   Q9NUZ3 (UniProtKB/Swiss-Prot),   Q8WZ06 (UniProtKB/Swiss-Prot),   Q5QTQ4 (UniProtKB/Swiss-Prot),   D3DPG7 (UniProtKB/Swiss-Prot),   B4DMW2 (UniProtKB/Swiss-Prot),   Q9P079 (UniProtKB/Swiss-Prot),   Q8WU90 (UniProtKB/Swiss-Prot),   B7Z592 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSP00000338788   ⟸   ENST00000337859
Ensembl Acc Id: ENSP00000415788   ⟸   ENST00000445547
Ensembl Acc Id: ENSP00000410981   ⟸   ENST00000421536
Ensembl Acc Id: ENSP00000407192   ⟸   ENST00000437396
Ensembl Acc Id: ENSP00000520825   ⟸   ENST00000718440
Protein Domains
C3H1-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8WU90-F1-model_v2 AlphaFold Q8WU90 1-426 view protein structure

Promoters
RGD ID:6862274
Promoter ID:EPDNEW_H4302
Type:initiation region
Name:ZC3H15_1
Description:zinc finger CCCH-type containing 15
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh382186,486,260 - 186,486,320EPDNEW
RGD ID:6798482
Promoter ID:HG_KWN:36281
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:OTTHUMT00000334547,   OTTHUMT00000334548,   OTTHUMT00000334549,   OTTHUMT00000334550,   OTTHUMT00000334551,   OTTHUMT00000334552,   OTTHUMT00000334553
Position:
Human AssemblyChrPosition (strand)Source
Build 362187,059,031 - 187,060,147 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:29528 AgrOrtholog
COSMIC ZC3H15 COSMIC
Ensembl Genes ENSG00000065548 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000337859 ENTREZGENE
  ENST00000337859.11 UniProtKB/Swiss-Prot
  ENST00000421536.5 UniProtKB/TrEMBL
  ENST00000437396.1 UniProtKB/TrEMBL
  ENST00000445547.1 UniProtKB/TrEMBL
Gene3D-CATH 6.20.400.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Zinc finger, CCCH-type UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000065548 GTEx
HGNC ID HGNC:29528 ENTREZGENE
Human Proteome Map ZC3H15 Human Proteome Map
InterPro ZC3H15/TMA46_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_CCCH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_CCCH_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:55854 UniProtKB/Swiss-Prot
NCBI Gene 55854 ENTREZGENE
OMIM 619704 OMIM
PANTHER ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 15 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC FINGER-CONTAINING PROTEIN P48ZNF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DFRP_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  zf-CCCH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA162409508 PharmGKB
PROSITE ZF_C3H1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART ZnF_C3H1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP CCCH zinc finger UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
UniProt B4DMW2 ENTREZGENE
  B7Z592 ENTREZGENE, UniProtKB/TrEMBL
  D3DPG7 ENTREZGENE
  F8WB26_HUMAN UniProtKB/TrEMBL
  F8WF67_HUMAN UniProtKB/TrEMBL
  H7C466_HUMAN UniProtKB/TrEMBL
  Q5QTQ4 ENTREZGENE
  Q8WU90 ENTREZGENE
  Q8WZ06 ENTREZGENE
  Q9NUZ3 ENTREZGENE
  Q9NZ37 ENTREZGENE
  Q9P079 ENTREZGENE
  ZC3HF_HUMAN UniProtKB/Swiss-Prot
UniProt Secondary B4DMW2 UniProtKB/Swiss-Prot
  D3DPG7 UniProtKB/Swiss-Prot
  Q5QTQ4 UniProtKB/Swiss-Prot
  Q8WZ06 UniProtKB/Swiss-Prot
  Q9NUZ3 UniProtKB/Swiss-Prot
  Q9NZ37 UniProtKB/Swiss-Prot
  Q9P079 UniProtKB/Swiss-Prot