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Gene: TCP1 (t-complex 1) Homo sapiens
Symbol: TCP1
Name: t-complex 1
Description: Exhibits ubiquitin protein ligase binding activity. Involved in several processes, including positive regulation of DNA biosynthetic process; positive regulation of telomerase RNA localization to Cajal body; and protein stabilization. Localizes to the centrosome; chaperonin-containing T-complex; and microtubule.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CCT-alpha; CCT1; CCTa; D6S230E; t-complex protein 1; T-complex protein 1 subunit alpha; T-complex protein 1, alpha subunit; tailless complex polypeptide 1; TCP-1-alpha
Mus musculus (house mouse) : Tcp1 (t-complex protein 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Tcp1 (t-complex 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tcp1 (t-complex 1)
Pan paniscus (bonobo/pygmy chimpanzee) : TCP1 (t-complex 1)
Canis lupus familiaris (dog) : TCP1 (t-complex 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tcp1 (t-complex 1)
Sus scrofa (pig) : TCP1 (t-complex 1)
Chlorocebus sabaeus (green monkey) : TCP1 (t-complex 1)
Heterocephalus glaber (naked mole-rat) : Tcp1 (t-complex 1)
more info ...
Related Pseudogenes: TCP1P1   TCP1P2   TCP1P3  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl6159,778,498 - 159,789,703 (-)Ensembl
GRCh386159,778,498 - 159,789,703 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh376160,199,530 - 160,212,135 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366160,119,520 - 160,130,725 (-)NCBINCBI36hg18NCBI36
Build 346160,169,941 - 160,181,146NCBI
Celera6160,845,607 - 160,856,819 (-)NCBI
Cytogenetic Map6q25.3NCBI
HuRef6157,669,773 - 157,680,978 (-)NCBIHuRef
CHM1_16160,461,821 - 160,473,042 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on TCP1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732136
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.