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Gene: EPN2 (epsin 2) Homo sapiens
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Symbol: EPN2
Name: epsin 2
RGD ID: 1351510
Description: Exhibits cadherin binding activity. Involved in negative regulation of sprouting angiogenesis; negative regulation of vascular endothelial growth factor receptor signaling pathway; and positive regulation of Notch signaling pathway. Localizes to intracellular membrane-bounded organelle.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: EHB21; EPS-15-interacting protein 2; Eps15 binding protein; epsin-2; KIAA1065
Orthologs:
Mus musculus (house mouse) : Epn2 (epsin 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Epn2 (epsin 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Epn2 (epsin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : EPN2 (epsin 2)
Canis lupus familiaris (dog) : EPN2 (epsin 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Epn2 (epsin 2)
Sus scrofa (pig) : EPN2 (epsin 2)
Chlorocebus sabaeus (African green monkey) : EPN2 (epsin 2)
Heterocephalus glaber (naked mole-rat) : Epn2 (epsin 2)
more info ...
Related Pseudogenes: AC009831.2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1719,215,615 - 19,336,715 (+)EnsemblGRCh38hg38GRCh38
GRCh381719,237,377 - 19,336,715 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371719,140,690 - 19,240,028 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361719,081,283 - 19,180,621 (+)NCBINCBI36hg18NCBI36
Build 341719,081,302 - 19,180,620NCBI
Celera1716,598,294 - 16,653,109 (+)NCBI
Cytogenetic Map17p11.2NCBI
HuRef1718,520,401 - 18,619,785 (+)NCBIHuRef
CHM1_11719,149,312 - 19,248,777 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on EPN2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1351510
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.