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Gene: ADCY2 (adenylate cyclase 2) Homo sapiens
Symbol: ADCY2
Name: adenylate cyclase 2
RGD ID: 734219
Description: Predicted to have adenylate cyclase activity; adenylate cyclase binding activity; and metal ion binding activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway; cAMP biosynthetic process; and cellular response to forskolin. Localizes to cytoplasm and plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 3',5'-cyclic AMP synthetase; AC2; adenylate cyclase 2 (brain); adenylate cyclase II; adenylate cyclase type 2; adenylate cyclase type II; adenylyl cyclase 2; ATP pyrophosphate-lyase 2; FLJ16822; FLJ45092; HBAC2; KIAA1060; MGC133314; type II adenylate cyclase
Mus musculus (house mouse) : Adcy2 (adenylate cyclase 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Adcy2 (adenylate cyclase 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adcy2 (adenylate cyclase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ADCY2 (adenylate cyclase 2)
Canis lupus familiaris (dog) : ADCY2 (adenylate cyclase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adcy2 (adenylate cyclase 2)
Sus scrofa (pig) : ADCY2 (adenylate cyclase 2)
Chlorocebus sabaeus (African green monkey) : ADCY2 (adenylate cyclase 2)
Heterocephalus glaber (naked mole-rat) : Adcy2 (adenylate cyclase 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl57,396,138 - 7,830,081 (+)EnsemblGRCh38hg38GRCh38
GRCh3857,396,138 - 7,830,081 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3757,396,343 - 7,830,194 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3657,449,343 - 7,883,194 (+)NCBINCBI36hg18NCBI36
Build 3457,449,344 - 7,883,194NCBI
Celera57,439,102 - 7,871,262 (+)NCBI
Cytogenetic Map5p15.31NCBI
HuRef57,725,521 - 7,811,956 (+)NCBIHuRef
HuRef57,378,757 - 7,709,814 (+)NCBIHuRef
CHM1_157,396,258 - 7,830,278 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ADCY2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 734219
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.