Adcy6 (adenylate cyclase 6) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Adcy6 (adenylate cyclase 6) Mus musculus
Analyze
Symbol: Adcy6
Name: adenylate cyclase 6
RGD ID: 10083
MGI Page MGI
Description: Enables calcium- and calmodulin-responsive adenylate cyclase activity and scaffold protein binding activity. Involved in several processes, including cAMP biosynthetic process; cellular response to forskolin; and cellular response to vasopressin. Located in plasma membrane. Is expressed in several structures, including adipose tissue; alimentary system; brain; cardiovascular system; and genitourinary system. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome. Orthologous to human ADCY6 (adenylate cyclase 6).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AC; AC6; adenylate cyclase type 6; adenylate cyclase type VI; adenylyl cyclase 6; ATP pyrophosphate-lyase 6; ca(2+)-inhibitable adenylyl cyclase; mKIAA0422
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391598,484,982 - 98,508,119 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1598,487,854 - 98,507,957 (-)EnsemblGRCm39 Ensembl
GRCm381598,589,978 - 98,610,287 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1598,589,973 - 98,610,076 (-)EnsemblGRCm38mm10GRCm38
MGSCv371598,420,409 - 98,438,064 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361598,418,012 - 98,435,667 (-)NCBIMGSCv36mm8
Celera15100,737,585 - 100,755,761 (-)NCBICelera
Cytogenetic Map15F1NCBI
cM Map1554.59NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(1->4)-beta-D-glucan  (EXP)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
2-bromohexadecanoic acid  (ISO)
2-butoxyethanol  (EXP)
2-methylcholine  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (EXP,ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (EXP)
acrylamide  (ISO)
aflatoxin B1  (EXP)
ammonium chloride  (ISO)
amphetamine  (ISO)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
Azoxymethane  (EXP)
azoxystrobin  (ISO)
benzo[a]pyrene  (EXP,ISO)
bexarotene  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
buspirone  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
carbamazepine  (ISO)
CGP 52608  (ISO)
chlordecone  (EXP)
chlorpyrifos  (ISO)
colforsin daropate hydrochloride  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (EXP)
dibutyl phthalate  (ISO)
diclofenac  (ISO)
diethylstilbestrol  (EXP,ISO)
diuron  (ISO)
dobutamine  (EXP)
elemental selenium  (ISO)
endosulfan  (ISO)
ethanol  (EXP,ISO)
flavonoids  (ISO)
flutamide  (ISO)
folic acid  (EXP)
folpet  (EXP)
FR900359  (ISO)
furan  (ISO)
glyphosate  (ISO)
imidacloprid  (ISO)
indometacin  (ISO)
isoprenaline  (EXP)
ketoconazole  (ISO)
L-ascorbic acid  (ISO)
leflunomide  (ISO)
Licarin A  (EXP)
manganese(II) chloride  (ISO)
methamphetamine  (EXP)
morphine  (ISO)
nickel atom  (ISO)
Nor-9-carboxy-delta9-THC  (ISO)
paclitaxel  (ISO)
paraquat  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
phenobarbital  (EXP)
phosgene  (EXP)
pirinixic acid  (EXP)
propiconazole  (EXP)
selenium atom  (ISO)
silicon dioxide  (ISO)
starch  (ISO)
sunitinib  (ISO)
tamoxifen  (EXP)
temozolomide  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (ISO)
thiabendazole  (ISO)
titanium dioxide  (EXP)
toluene 2,4-diisocyanate  (EXP)
triclosan  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cilium  (IEA)
endosome  (ISO)
membrane  (ISO,ISS)
microvillus membrane  (ISO)
plasma membrane  (IBA,IDA,ISO)
sarcolemma  (ISO)
stereocilium  (IEA)

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Physiology and pathophysiology of the vasopressin-regulated renal water reabsorption. Boone M and Deen PM, Pflugers Arch. 2008 Sep;456(6):1005-24. Epub 2008 Apr 23.
2. Cellular localization of type 5 and type 6 ACs in collecting duct and regulation of cAMP synthesis. Helies-Toussaint C, etal., Am J Physiol Renal Physiol. 2000 Jul;279(1):F185-94.
3. Angiotensin II regulates V2 receptor and pAQP2 during ureteral obstruction. Jensen AM, etal., Am J Physiol Renal Physiol. 2009 Jan;296(1):F127-34. Epub 2008 Oct 29.
4. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
5. Indomethacin enhances shuttling of aquaporin-2 despite decreased abundance in rat kidney. Kim SW, etal., J Am Soc Nephrol. 2004 Dec;15(12):2998-3005.
6. Glucagon-mediated internalization of serine-phosphorylated glucagon receptor and Gsalpha in rat liver. Merlen C, etal., FEBS Lett. 2006 Oct 16;580(24):5697-704. Epub 2006 Sep 20.
7. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
8. MGDs mouse GO annotations MGD data from the GO Consortium
9. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
10. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
11. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
12. Mouse MP Annotation Import Pipeline RGD automated import pipeline
13. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
15. Physiological roles for G protein-regulated adenylyl cyclase isoforms: insights from knockout and overexpression studies. Sadana R and Dessauer CW, Neurosignals. 2009;17(1):5-22. Epub 2008 Oct 24.
Additional References at PubMed
PMID:1332848   PMID:1379717   PMID:7766992   PMID:9611134   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11805091   PMID:12297500   PMID:12477932   PMID:12613887  
PMID:12693553   PMID:14610273   PMID:14681479   PMID:15007069   PMID:15582152   PMID:16141072   PMID:16141073   PMID:16602821   PMID:16615126   PMID:17068292   PMID:17110384   PMID:17229090  
PMID:17567809   PMID:17593019   PMID:17597072   PMID:18071070   PMID:18835269   PMID:19734365   PMID:19889965   PMID:20056751   PMID:20164376   PMID:20348281   PMID:20359598   PMID:20371630  
PMID:20431059   PMID:20466003   PMID:20562336   PMID:20861226   PMID:20864687   PMID:21195051   PMID:21282557   PMID:21873635   PMID:21937603   PMID:21986494   PMID:22641646   PMID:22794259  
PMID:22832924   PMID:22952279   PMID:23123217   PMID:23264685   PMID:23587598   PMID:23609114   PMID:23726959   PMID:23753526   PMID:24158982   PMID:24194600   PMID:24218452   PMID:24277577  
PMID:24431204   PMID:24854272   PMID:24944202   PMID:24994926   PMID:25205328   PMID:26410627   PMID:26932446   PMID:27643574   PMID:27826057   PMID:28405619   PMID:28767701   PMID:28870220  
PMID:29903911   PMID:29941522   PMID:30301777   PMID:30624615   PMID:31009605   PMID:31162142   PMID:31173603   PMID:31918924   PMID:32683324   PMID:32702291   PMID:37127773   PMID:38355793  
PMID:38653356  


Genomics

Comparative Map Data
Adcy6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391598,484,982 - 98,508,119 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1598,487,854 - 98,507,957 (-)EnsemblGRCm39 Ensembl
GRCm381598,589,978 - 98,610,287 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1598,589,973 - 98,610,076 (-)EnsemblGRCm38mm10GRCm38
MGSCv371598,420,409 - 98,438,064 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361598,418,012 - 98,435,667 (-)NCBIMGSCv36mm8
Celera15100,737,585 - 100,755,761 (-)NCBICelera
Cytogenetic Map15F1NCBI
cM Map1554.59NCBI
ADCY6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381248,766,194 - 48,789,974 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1248,766,194 - 48,789,089 (-)EnsemblGRCh38hg38GRCh38
GRCh371249,159,977 - 49,183,757 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361247,446,248 - 47,469,087 (-)NCBINCBI36Build 36hg18NCBI36
Build 341247,446,247 - 47,469,087NCBI
Celera1247,955,885 - 47,978,715 (-)NCBICelera
Cytogenetic Map12q13.12NCBI
HuRef1246,193,406 - 46,216,105 (-)NCBIHuRef
CHM1_11249,125,807 - 49,148,636 (-)NCBICHM1_1
T2T-CHM13v2.01248,728,221 - 48,752,002 (-)NCBIT2T-CHM13v2.0
Adcy6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87131,621,860 - 131,642,923 (-)NCBIGRCr8
mRatBN7.27129,742,827 - 129,763,922 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7129,742,838 - 129,763,754 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7131,550,191 - 131,571,121 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07133,775,741 - 133,796,673 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07133,688,243 - 133,709,175 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07140,270,678 - 140,291,722 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7140,270,692 - 140,291,620 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X114,774,376 - 114,795,062 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47137,339,933 - 137,360,020 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17137,418,113 - 137,437,246 (-)NCBI
Celera7126,233,455 - 126,254,162 (-)NCBICelera
Cytogenetic Map7q36NCBI
Adcy6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555007,637,089 - 7,651,162 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555007,635,946 - 7,655,579 (-)NCBIChiLan1.0ChiLan1.0
ADCY6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21045,391,604 - 45,415,339 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11245,388,364 - 45,412,100 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01239,957,394 - 39,981,049 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11240,836,922 - 40,859,131 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1240,836,922 - 40,859,131 (+)Ensemblpanpan1.1panPan2
ADCY6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1275,739,514 - 5,752,888 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl275,733,586 - 5,752,888 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2740,504,946 - 40,518,306 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0275,784,673 - 5,805,753 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl275,788,872 - 5,805,745 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1275,754,314 - 5,767,654 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0275,744,379 - 5,757,707 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02740,897,201 - 40,910,552 (-)NCBIUU_Cfam_GSD_1.0
Adcy6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494566,529,608 - 66,572,952 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365126,615,012 - 6,629,165 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365126,612,708 - 6,629,202 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADCY6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl514,834,426 - 14,850,728 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1514,834,420 - 14,855,309 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2515,128,970 - 15,146,987 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ADCY6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11145,006,220 - 45,031,481 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1145,005,637 - 45,025,501 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037201,115,865 - 201,140,244 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Adcy6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248163,366,744 - 3,387,447 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248163,366,594 - 3,387,431 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Adcy6
860 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:1034
Count of miRNA genes:547
Interacting mature miRNAs:665
Transcripts:ENSMUST00000096224
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884442Sklq6_mskull length QTL 6, 5 week (mouse)156129481100797881Mouse
1300627Sluc26_msusceptibility to lung cancer 26 (mouse)Not determined1570345653104073951Mouse
1357526Hyplip2_mhyperlipidemia 2 (mouse)Not determined1512402203102896555Mouse
11528547Sluc34_msusceptibility to lung cancer 34 (mouse)1597884933102896555Mouse
1301918Skull22_mskull morphology 22 (mouse)Not determined1585901546104073951Mouse
14928306Manh79_mmandible shape 79 (mouse)1578847557104073951Mouse
1357894Epfpq3_mepididymal fat percentage QTL 3 (mouse)Not determined1578601103102901704Mouse
26884425Cvht2_mcranial vault height 2, 5 week (mouse)1528800146102008435Mouse
4142060W3q6_mweight 3 weeks QTL 6 (mouse)Not determined78601103102901704Mouse
12791003Aath8_maortic arch atherosclerosis 8 (mouse)1573430144104073951Mouse
11530038Sluc34b_msusceptibility to lung cancer 34b (mouse)1585896437104073951Mouse
11530037Sluc34a_msusceptibility to lung cancer 34a (mouse)1585896437104073951Mouse
1558985Eae32_mexperimental allergic encephalomyelitis susceptibility 32 (mouse)Not determined1532578416103425899Mouse
4141921Pstc3_mperiosteal circumference 3 (mouse)Not determined1567270698101270847Mouse
12880411V125Dq11_mvitamin D active form serum level QTL 11 (mouse)1578897881104073951Mouse
1301171Brm2_mbrachyury modifier 2 (mouse)Not determined156552537699525499Mouse
1300851Heal4_mwound healing/regeneration 4 (mouse)Not determined1577527592104073951Mouse
14747011Mancz13_mmandible centroid size 13 (mouse)1572382669104073951Mouse
10402490Dipa5_mdrug induced psychomotor activation 5 (mouse)Not determined1579163411104073951Mouse
1300726Pitm4_mprion incubation time 4 (mouse)Not determined1570349271104073951Mouse
1302197Bhr2_mbronchial hyperresponsiveness 2 (mouse)Not determined1564306334103425899Mouse
1302074Bmd4_mbone mineral density 4 (mouse)Not determined1556186708103425899Mouse
1301119Drb7_mdopamine receptor binding 7 (mouse)Not determined156533657899341028Mouse
4141135Cia35_mcollagen induced arthritis 35 (mouse)Not determined156481182698811946Mouse
4141902Cia37_mcollagen induced arthritis 37 (mouse)Not determined1580884933104073951Mouse
14700689Carg5_mCandida albicans resistance gene 5 (mouse)1597697881103008427Mouse
4141581Dshv1_mdorsal hippocampal volume 1 (mouse)Not determined92788640103425899Mouse
26884399Humsd1_mhumerus midshaft diameter 1, 5 week (mouse)1548363396101708435Mouse
4141897Imrfq2_mimmune response to Factor IX QTL 2 (mouse)Not determined79908940104073951Mouse
1301284Cosz3_mcocaine seizure 3 (mouse)Not determined1580313634104073951Mouse
4141511Gdcr1_mglycerolphosphate dehydrogenase regulator 1 (mouse)Not determined82615474104073951Mouse
1357614Bmca_mbile mucin accumulation (mouse)Not determined1585896437104073951Mouse
1300648Dbsty4_mdiabesity 4 (mouse)Not determined1570349271104073951Mouse
1300974Pgia9_mproteoglycan induced arthritis 9 (mouse)Not determined1580884933104073951Mouse

Markers in Region
M93422  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381598,591,151 - 98,591,377UniSTSGRCm38
MGSCv371598,421,582 - 98,421,808UniSTSGRCm37
Celera15100,738,756 - 100,738,982UniSTS
Cytogenetic Map15FUniSTS
Whitehead/MRC_RH15871.59UniSTS
Whitehead_YAC15 UniSTS
R74960  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381598,606,498 - 98,606,687UniSTSGRCm38
MGSCv371598,436,929 - 98,437,118UniSTSGRCm37
Celera15100,754,626 - 100,754,815UniSTS
Cytogenetic Map15FUniSTS
Whitehead_YAC15 UniSTS
RH125612  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381598,606,483 - 98,606,616UniSTSGRCm38
MGSCv371598,436,914 - 98,437,047UniSTSGRCm37
Celera15100,754,611 - 100,754,744UniSTS
Cytogenetic Map15FUniSTS
D15Bwg0340e  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381598,606,432 - 98,606,707UniSTSGRCm38
MGSCv371598,436,863 - 98,437,138UniSTSGRCm37
Celera15100,754,560 - 100,754,835UniSTS
Cytogenetic Map15FUniSTS
cM Map1555.8UniSTS
M93422  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381598,590,623 - 98,590,717UniSTSGRCm38
MGSCv371598,421,054 - 98,421,148UniSTSGRCm37
Celera15100,738,228 - 100,738,322UniSTS
Cytogenetic Map15FUniSTS
Whitehead/MRC_RH15871.59UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001368413 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410363 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410364 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410365 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410367 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001410368 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006520303 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036159076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001781491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004938785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004938786 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_383972 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC138221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK078078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK122279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK147516 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC145101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU611374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466550 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M93422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M96653 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000096224   ⟹   ENSMUSP00000093939
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1598,487,854 - 98,505,514 (-)Ensembl
GRCm38.p6 Ensembl1598,589,973 - 98,607,633 (-)Ensembl
Ensembl Acc Id: ENSMUST00000226236
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1598,487,873 - 98,494,857 (-)Ensembl
GRCm38.p6 Ensembl1598,589,992 - 98,596,976 (-)Ensembl
Ensembl Acc Id: ENSMUST00000226500   ⟹   ENSMUSP00000154693
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1598,502,482 - 98,507,913 (-)Ensembl
GRCm38.p6 Ensembl1598,604,601 - 98,610,032 (-)Ensembl
Ensembl Acc Id: ENSMUST00000227501   ⟹   ENSMUSP00000154012
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1598,502,031 - 98,507,957 (-)Ensembl
GRCm38.p6 Ensembl1598,604,150 - 98,610,076 (-)Ensembl
Ensembl Acc Id: ENSMUST00000228566   ⟹   ENSMUSP00000154421
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1598,490,025 - 98,502,612 (-)Ensembl
GRCm38.p6 Ensembl1598,592,144 - 98,604,731 (-)Ensembl
Ensembl Acc Id: ENSMUST00000228596
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1598,490,588 - 98,492,115 (-)Ensembl
GRCm38.p6 Ensembl1598,592,707 - 98,594,234 (-)Ensembl
Ensembl Acc Id: ENSMUST00000228903   ⟹   ENSMUSP00000154696
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1598,489,464 - 98,502,707 (-)Ensembl
GRCm38.p6 Ensembl1598,591,583 - 98,604,826 (-)Ensembl
RefSeq Acc Id: NM_001368413   ⟹   NP_001355342
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391598,487,859 - 98,505,514 (-)NCBI
GRCm381598,589,978 - 98,604,732 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001410361   ⟹   NP_001397290
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391598,487,859 - 98,508,119 (-)NCBI
RefSeq Acc Id: NM_001410362   ⟹   NP_001397291
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391598,487,859 - 98,507,973 (-)NCBI
RefSeq Acc Id: NM_001410363   ⟹   NP_001397292
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391598,487,859 - 98,507,973 (-)NCBI
RefSeq Acc Id: NM_001410364   ⟹   NP_001397293
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391598,487,859 - 98,507,799 (-)NCBI
RefSeq Acc Id: NM_001410365   ⟹   NP_001397294
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391598,487,859 - 98,506,915 (-)NCBI
RefSeq Acc Id: NM_001410366   ⟹   NP_001397295
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391598,487,859 - 98,506,803 (-)NCBI
RefSeq Acc Id: NM_001410367   ⟹   NP_001397296
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391598,487,859 - 98,504,876 (-)NCBI
RefSeq Acc Id: NM_001410368   ⟹   NP_001397297
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391598,487,859 - 98,504,876 (-)NCBI
RefSeq Acc Id: XM_006520303   ⟹   XP_006520366
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391598,484,982 - 98,504,661 (-)NCBI
GRCm381598,589,978 - 98,606,781 (-)NCBI
Sequence:
RefSeq Acc Id: XM_036159076   ⟹   XP_036014969
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391598,488,498 - 98,507,968 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001781491
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391598,484,982 - 98,504,662 (-)NCBI
GRCm381598,589,978 - 98,606,782 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004938785
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391598,488,498 - 98,506,309 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004938786
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391598,484,982 - 98,504,663 (-)NCBI
Sequence:
RefSeq Acc Id: XR_383972
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391598,494,033 - 98,504,663 (-)NCBI
GRCm381598,596,152 - 98,606,783 (-)NCBI
Sequence:
RefSeq Acc Id: XP_006520366   ⟸   XM_006520303
- Peptide Label: isoform X1
- UniProtKB: F8VQ52 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001355342   ⟸   NM_001368413
- Peptide Label: isoform 2
- UniProtKB: A0A2I3BRC5 (UniProtKB/TrEMBL),   F8VQ52 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSMUSP00000154012   ⟸   ENSMUST00000227501
Ensembl Acc Id: ENSMUSP00000154693   ⟸   ENSMUST00000226500
Ensembl Acc Id: ENSMUSP00000154696   ⟸   ENSMUST00000228903
Ensembl Acc Id: ENSMUSP00000154421   ⟸   ENSMUST00000228566
Ensembl Acc Id: ENSMUSP00000093939   ⟸   ENSMUST00000096224
RefSeq Acc Id: XP_036014969   ⟸   XM_036159076
- Peptide Label: isoform X5
- UniProtKB: A0A2I3BRC5 (UniProtKB/TrEMBL),   F8VQ52 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001397290   ⟸   NM_001410361
- Peptide Label: isoform 2
- UniProtKB: F8VQ52 (UniProtKB/TrEMBL),   A0A2I3BRC5 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001397291   ⟸   NM_001410362
- Peptide Label: isoform 3
- UniProtKB: F8VQ52 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001397292   ⟸   NM_001410363
- Peptide Label: isoform 4
- UniProtKB: F8VQ52 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001397293   ⟸   NM_001410364
- Peptide Label: isoform 2
- UniProtKB: F8VQ52 (UniProtKB/TrEMBL),   A0A2I3BRC5 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001397294   ⟸   NM_001410365
- Peptide Label: isoform 5
- UniProtKB: F8VQ52 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001397295   ⟸   NM_001410366
- Peptide Label: isoform 6
- UniProtKB: F8VQ52 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001397297   ⟸   NM_001410368
- Peptide Label: isoform 8
- UniProtKB: F8VQ52 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001397296   ⟸   NM_001410367
- Peptide Label: isoform 7
- UniProtKB: F8VQ52 (UniProtKB/TrEMBL)
Protein Domains
Adenylate cyclase N-terminal   Guanylate cyclase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q01341-F1-model_v2 AlphaFold Q01341 1-1165 view protein structure

Promoters
RGD ID:6847161
Promoter ID:MM_ACW:19275
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:ADCY6.CSEP07,   ADCY6.HSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361598,424,556 - 98,425,056 (-)MPROMDB
RGD ID:6825711
Promoter ID:MM_KWN:19623
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney,   Liver,   Lung
Transcripts:UC007XMZ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361598,434,661 - 98,436,072 (-)MPROMDB
RGD ID:6825707
Promoter ID:MM_KWN:19624
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   Kidney,   Lung
Transcripts:NM_007405
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361598,438,011 - 98,438,962 (-)MPROMDB
RGD ID:6847160
Promoter ID:MM_ACW:19277
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Kidney
Transcripts:ADCY6.BSEP07,   ADCY6.ESEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361598,440,021 - 98,440,521 (-)MPROMDB
RGD ID:8684920
Promoter ID:EPDNEW_M20491
Type:multiple initiation site
Name:Adcy6_1
Description:Mus musculus adenylate cyclase 6 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381598,607,633 - 98,607,693EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:87917 AgrOrtholog
Ensembl Genes ENSMUSG00000022994 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000096224 ENTREZGENE
  ENSMUST00000096224.6 UniProtKB/TrEMBL
  ENSMUST00000226500.2 UniProtKB/TrEMBL
  ENSMUST00000227501.2 UniProtKB/TrEMBL
  ENSMUST00000228566 ENTREZGENE
  ENSMUST00000228566.2 UniProtKB/TrEMBL
  ENSMUST00000228903.2 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.1230 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro A/G_cyclase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  A/G_cyclase_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  AC_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Adcy UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Adcy_conserved_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nucleotide_cyclase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:87917 ENTREZGENE
NCBI Gene 11512 ENTREZGENE
PANTHER ADENYLATE CYCLASE TYPE 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ADENYLATE CYCLASE TYPE 6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam AC_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DUF1053 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Guanylate_cyc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Adcy6 PhenoGen
PIRSF Ade_cyc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE GUANYLATE_CYCLASE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GUANYLATE_CYCLASE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART CYCc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF55073 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A2I3BQ20_MOUSE UniProtKB/TrEMBL
  A0A2I3BRC5 ENTREZGENE, UniProtKB/TrEMBL
  A0A2I3BRS6_MOUSE UniProtKB/TrEMBL
  A0A2I3BS04_MOUSE UniProtKB/TrEMBL
  ADCY6_MOUSE UniProtKB/Swiss-Prot
  F8VQ52 ENTREZGENE, UniProtKB/TrEMBL
  Q01341 ENTREZGENE