SLC13A4 (solute carrier family 13 member 4) - Rat Genome Database
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Gene: SLC13A4 (solute carrier family 13 member 4) Homo sapiens
Analyze
Symbol: SLC13A4
Name: solute carrier family 13 member 4
RGD ID: 1345589
HGNC Page HGNC
Description: Predicted to have sodium:sulfate symporter activity. Predicted to be involved in anion transmembrane transport. Predicted to localize to integral component of membrane; INTERACTS WITH 2-hydroxypropanoic acid; 4,4'-sulfonyldiphenol; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Na(+)/sulfate cotransporter SUT-1; naS2; solute carrier family 13 (sodium/sulfate symporter), member 4; solute carrier family 13 (sodium/sulfate symporters), member 4; solute carrier family 13 (sodium/sulphate symporters), member 4; sulphate transporter 1; SUT-1; SUT1
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl7135,681,237 - 135,729,258 (-)EnsemblGRCh38hg38GRCh38
GRCh387135,681,231 - 135,728,186 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh377135,365,979 - 135,412,934 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh377135,365,979 - 135,412,943 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367135,016,525 - 135,063,473 (-)NCBINCBI36hg18NCBI36
Build 347134,823,243 - 134,870,188NCBI
Celera7130,103,444 - 130,150,391 (-)NCBI
Cytogenetic Map7q33NCBI
HuRef7129,668,796 - 129,716,167 (-)NCBIHuRef
CHM1_17135,299,894 - 135,346,845 (-)NCBICHM1_1
CRA_TCAGchr7v27134,710,411 - 134,757,363 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
1. GOA_HUMAN data from the GO Consortium
2. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10535998   PMID:12477932   PMID:12690205   PMID:15607730   PMID:16211368   PMID:20379614   PMID:21873635   PMID:23453247   PMID:23485456   PMID:28385533   PMID:30575818   PMID:31741433  
PMID:32296183  


Genomics

Comparative Map Data
SLC13A4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl7135,681,237 - 135,729,258 (-)EnsemblGRCh38hg38GRCh38
GRCh387135,681,231 - 135,728,186 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh377135,365,979 - 135,412,934 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh377135,365,979 - 135,412,943 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 367135,016,525 - 135,063,473 (-)NCBINCBI36hg18NCBI36
Build 347134,823,243 - 134,870,188NCBI
Celera7130,103,444 - 130,150,391 (-)NCBI
Cytogenetic Map7q33NCBI
HuRef7129,668,796 - 129,716,167 (-)NCBIHuRef
CHM1_17135,299,894 - 135,346,845 (-)NCBICHM1_1
CRA_TCAGchr7v27134,710,411 - 134,757,363 (-)NCBI
Slc13a4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39635,244,888 - 35,285,061 (-)NCBIGRCm39mm39
GRCm38635,267,953 - 35,308,126 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl635,267,957 - 35,308,131 (-)EnsemblGRCm38mm10GRCm38
MGSCv37635,217,953 - 35,258,126 (-)NCBIGRCm37mm9NCBIm37
MGSCv36635,198,110 - 35,238,278 (-)NCBImm8
Celera635,268,639 - 35,308,823 (-)NCBICelera
Cytogenetic Map6B1NCBI
Slc13a4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2463,943,369 - 63,988,852 (-)NCBI
Rnor_6.0 Ensembl462,797,677 - 62,840,357 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0462,796,732 - 62,841,053 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0462,519,667 - 62,563,986 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4462,679,593 - 62,724,547 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1462,955,724 - 63,000,677 (-)NCBI
Celera458,992,508 - 59,035,406 (-)NCBICelera
Cytogenetic Map4q22NCBI
Slc13a4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554947,014,252 - 7,055,514 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554947,013,577 - 7,057,767 (+)NCBIChiLan1.0ChiLan1.0
SLC13A4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.17140,150,963 - 140,197,418 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7140,150,963 - 140,197,418 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v07127,653,170 - 127,700,080 (-)NCBIMhudiblu_PPA_v0panPan3
SLC13A4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1612,540,263 - 12,579,949 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11612,539,369 - 12,581,155 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Slc13a4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936592450,237 - 497,050 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC13A4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11813,593,735 - 13,641,649 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21814,326,517 - 14,368,472 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SLC13A4
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.121104,359,577 - 104,407,905 (-)NCBI
ChlSab1.1 Ensembl21104,363,792 - 104,405,562 (-)Ensembl
Slc13a4
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476515,960,269 - 16,001,700 (-)NCBI

Position Markers
D7S2867  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh377135,366,124 - 135,366,273UniSTSGRCh37
Build 367135,016,664 - 135,016,813RGDNCBI36
Celera7130,103,583 - 130,103,732RGD
Cytogenetic Map7q33UniSTS
HuRef7129,668,935 - 129,669,084UniSTS
CRA_TCAGchr7v27134,710,550 - 134,710,699UniSTS
GeneMap99-G3 RH Map77527.0UniSTS
RH92554  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh377135,379,559 - 135,379,678UniSTSGRCh37
Build 367135,030,099 - 135,030,218RGDNCBI36
Celera7130,117,029 - 130,117,148RGD
Cytogenetic Map7q33UniSTS
HuRef7129,682,388 - 129,682,507UniSTS
CRA_TCAGchr7v27134,723,996 - 134,724,115UniSTS
GeneMap99-GB4 RH Map7610.36UniSTS
RH46984  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh377135,414,499 - 135,414,619UniSTSGRCh37
Build 367135,065,039 - 135,065,159RGDNCBI36
Celera7130,151,957 - 130,152,077RGD
Cytogenetic Map7q33UniSTS
HuRef7129,717,733 - 129,717,853UniSTS
CRA_TCAGchr7v27134,758,930 - 134,759,050UniSTS
GeneMap99-GB4 RH Map7612.18UniSTS
A005R34  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh377135,366,046 - 135,366,273UniSTSGRCh37
Build 367135,016,586 - 135,016,813RGDNCBI36
Celera7130,103,505 - 130,103,732RGD
Cytogenetic Map7q33UniSTS
HuRef7129,668,857 - 129,669,084UniSTS
CRA_TCAGchr7v27134,710,472 - 134,710,699UniSTS
GeneMap99-GB4 RH Map7610.36UniSTS
D7S2118E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh377135,366,092 - 135,366,228UniSTSGRCh37
Build 367135,016,632 - 135,016,768RGDNCBI36
Celera7130,103,551 - 130,103,687RGD
Cytogenetic Map7q33UniSTS
HuRef7129,668,903 - 129,669,039UniSTS
CRA_TCAGchr7v27134,710,518 - 134,710,654UniSTS
GeneMap99-GB4 RH Map7610.36UniSTS
SHGC-67307  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map15q22.3UniSTS
Cytogenetic Map20q13.3UniSTS
Cytogenetic Map7q11.23UniSTS
Cytogenetic Map7p13UniSTS
Cytogenetic Map19q13.32UniSTS
Cytogenetic Map19q13.43UniSTS
Cytogenetic Map3q21.2UniSTS
Cytogenetic Map3p21.3UniSTS
Cytogenetic Map18q11.2UniSTS
Cytogenetic Map19q13.3UniSTS
Cytogenetic MapXp11.3UniSTS
Cytogenetic Map7q21.2UniSTS
Cytogenetic Map13q14UniSTS
Cytogenetic Map19p13.3UniSTS
Cytogenetic Map18pter-p11.3UniSTS
Cytogenetic Map7p22.2UniSTS
Cytogenetic Map8q24.3UniSTS
Cytogenetic Map22q11.21UniSTS
Cytogenetic Map4q13.1UniSTS
Cytogenetic Map6p25UniSTS
Cytogenetic Map13q34UniSTS
Cytogenetic Map8q24.22UniSTS
Cytogenetic Map16q21UniSTS
Cytogenetic Map1p35.2UniSTS
Cytogenetic Map1q25.1UniSTS
Cytogenetic Map12q13.3UniSTS
Cytogenetic Map11q13UniSTS
Cytogenetic Map8q21.1UniSTS
Cytogenetic Map19q13.12UniSTS
Cytogenetic Map1p13.3UniSTS
Cytogenetic Map6q22.31UniSTS
Cytogenetic Map7p11.2UniSTS
Cytogenetic Map7q34UniSTS
Cytogenetic Map12q24.31UniSTS
Cytogenetic Map12q24.23UniSTS
Cytogenetic Map9p13.3UniSTS
Cytogenetic Map3p21.1UniSTS
Cytogenetic Map21q22.3UniSTS
Cytogenetic Map2q24.2UniSTS
Cytogenetic Map2p25.1-p24.1UniSTS
Cytogenetic Map5q32UniSTS
Cytogenetic Map5q31UniSTS
Cytogenetic Map19q13.4UniSTS
Cytogenetic Map16p13.3UniSTS
Cytogenetic Map16q22.2UniSTS
Cytogenetic Map1q32.2-q41UniSTS
Cytogenetic Map17q21.31UniSTS
Cytogenetic Map14q12UniSTS
Cytogenetic Map16q24.3UniSTS
Cytogenetic Map17q24.1UniSTS
Cytogenetic Map22q13.1UniSTS
Cytogenetic Map16p13UniSTS
Cytogenetic Map1q32UniSTS
Cytogenetic MapXp22.3UniSTS
Cytogenetic Map14q11.2UniSTS
Cytogenetic Map6p22.3UniSTS
Cytogenetic Map6p25.2UniSTS
Cytogenetic Map14q22.1UniSTS
Cytogenetic Map1p34.3UniSTS
Cytogenetic Map7q22.1UniSTS
Cytogenetic Map7p15.3UniSTS
Cytogenetic Map1q25.3UniSTS
Cytogenetic Map15q22.2UniSTS
Cytogenetic Map20q12UniSTS
Cytogenetic Map4p15.32UniSTS
Cytogenetic Map19q13.42UniSTS
Cytogenetic Map12q24.13UniSTS
Cytogenetic Map20q11.22UniSTS
Cytogenetic Map6p12.3UniSTS
Cytogenetic Map7q33UniSTS
Cytogenetic Map15q13.2UniSTS
Cytogenetic Map8q22.1UniSTS
Cytogenetic Map17q21UniSTS
Cytogenetic Map22q11.1UniSTS
Cytogenetic Map7q22UniSTS
Cytogenetic Map6q21UniSTS
Cytogenetic Map1p36.13UniSTS
Cytogenetic Map5p13.3UniSTS
Cytogenetic Map2p23.3UniSTS
Cytogenetic Map19q13UniSTS
Cytogenetic Map4q26UniSTS
Cytogenetic Map10q11.23UniSTS
Cytogenetic Map16p13.12UniSTS
Cytogenetic Map17q12UniSTS
Cytogenetic Map16q23.1UniSTS
Cytogenetic Map19p13.2UniSTS
Cytogenetic Map15q15.3UniSTS
Cytogenetic Map2q35UniSTS
Cytogenetic Map22q13.2UniSTS
Cytogenetic Map18q21.32UniSTS
Cytogenetic Map5q22.1UniSTS
Cytogenetic Map1p36.12UniSTS
Cytogenetic Map14q32.12UniSTS
Cytogenetic Map12q13UniSTS
Cytogenetic Map11q13.1UniSTS
Cytogenetic Map14q32.31UniSTS
Cytogenetic Map17q21.2UniSTS
Cytogenetic Map11q13.5UniSTS
Cytogenetic Map15q25.2UniSTS
Cytogenetic Map22q12.1UniSTS
Cytogenetic Map7p14.3UniSTS
Cytogenetic Map20q13.33UniSTS
Cytogenetic Map1p36.21UniSTS
TNG Radiation Hybrid Map41213.0UniSTS
G32281  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh377135,366,046 - 135,366,273UniSTSGRCh37
Celera7130,103,505 - 130,103,732UniSTS
Cytogenetic Map7q33UniSTS
HuRef7129,668,857 - 129,669,084UniSTS
CRA_TCAGchr7v27134,710,472 - 134,710,699UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:563
Count of miRNA genes:382
Interacting mature miRNAs:415
Transcripts:ENST00000354042, ENST00000471405, ENST00000478310, ENST00000480376, ENST00000491630
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component
High
Medium 2 12 3 4 1 69 216 4 1 3
Low 646 1202 677 174 376 109 2673 429 1614 143 821 761 72 1 439 1546 2
Below cutoff 1744 1701 1001 421 1385 328 1658 1737 2030 248 386 775 96 765 1239

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000354042   ⟹   ENSP00000297282
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl7135,681,237 - 135,728,186 (-)Ensembl
RefSeq Acc Id: ENST00000378428   ⟹   ENSP00000476620
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl7135,708,141 - 135,729,226 (-)Ensembl
RefSeq Acc Id: ENST00000422620   ⟹   ENSP00000477467
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl7135,721,393 - 135,729,258 (-)Ensembl
RefSeq Acc Id: ENST00000471405
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl7135,681,241 - 135,728,204 (-)Ensembl
RefSeq Acc Id: ENST00000478310
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl7135,707,437 - 135,728,174 (-)Ensembl
RefSeq Acc Id: ENST00000480376
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl7135,699,364 - 135,705,807 (-)Ensembl
RefSeq Acc Id: ENST00000491630
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl7135,681,237 - 135,685,685 (-)Ensembl
RefSeq Acc Id: NM_001318192   ⟹   NP_001305121
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387135,681,231 - 135,728,186 (-)NCBI
CHM1_17135,299,894 - 135,346,845 (-)NCBI
Sequence:
RefSeq Acc Id: NM_012450   ⟹   NP_036582
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387135,681,231 - 135,728,186 (-)NCBI
GRCh377135,365,979 - 135,412,943 (-)NCBI
Build 367135,016,525 - 135,063,473 (-)NCBI Archive
Celera7130,103,444 - 130,150,391 (-)RGD
HuRef7129,668,796 - 129,716,167 (-)RGD
CHM1_17135,299,894 - 135,346,845 (-)NCBI
CRA_TCAGchr7v27134,710,411 - 134,757,363 (-)RGD
Sequence:
RefSeq Acc Id: XM_011516024   ⟹   XP_011514326
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387135,681,241 - 135,727,900 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017011962   ⟹   XP_016867451
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387135,681,241 - 135,707,041 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017011963   ⟹   XP_016867452
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387135,693,821 - 135,727,879 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_036582   ⟸   NM_012450
- Peptide Label: isoform 2
- UniProtKB: Q9UKG4 (UniProtKB/Swiss-Prot),   Q59HF0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011514326   ⟸   XM_011516024
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: NP_001305121   ⟸   NM_001318192
- Peptide Label: isoform 1
- UniProtKB: Q9UKG4 (UniProtKB/Swiss-Prot),   Q59HF0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_016867451   ⟸   XM_017011962
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_016867452   ⟸   XM_017011963
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSP00000476620   ⟸   ENST00000378428
RefSeq Acc Id: ENSP00000297282   ⟸   ENST00000354042
RefSeq Acc Id: ENSP00000477467   ⟸   ENST00000422620

Promoters
RGD ID:6806263
Promoter ID:HG_KWN:59834
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562
Transcripts:UC003VTC.1
Position:
Human AssemblyChrPosition (strand)Source
Build 367135,063,386 - 135,063,886 (-)MPROMDB
RGD ID:7212001
Promoter ID:EPDNEW_H11745
Type:multiple initiation site
Name:SLC13A4_1
Description:solute carrier family 13 member 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh387135,728,186 - 135,728,246EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 7q32.1-36.3(chr7:129310166-159282390)x3 copy number gain See cases [RCV000050876] Chr7:129310166..159282390 [GRCh38]
Chr7:128950007..159075079 [GRCh37]
Chr7:128737243..158767840 [NCBI36]
Chr7:7q32.1-36.3
pathogenic
GRCh38/hg38 7q32.3-36.3(chr7:132850196-159325876)x3 copy number gain See cases [RCV000051101] Chr7:132850196..159325876 [GRCh38]
Chr7:132534956..159118566 [GRCh37]
Chr7:132185496..158811327 [NCBI36]
Chr7:7q32.3-36.3
pathogenic
GRCh38/hg38 7p22.3-q36.3(chr7:53985-159282531)x1 copy number loss See cases [RCV000052250] Chr7:53985..159282531 [GRCh38]
Chr7:53985..159075220 [GRCh37]
Chr7:149068..158767981 [NCBI36]
Chr7:7p22.3-q36.3
pathogenic
GRCh38/hg38 7q32.3-36.1(chr7:132023155-149309794)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000054172]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000054172]|See cases [RCV000054172] Chr7:132023155..149309794 [GRCh38]
Chr7:131707914..149006885 [GRCh37]
Chr7:131358454..148637818 [NCBI36]
Chr7:7q32.3-36.1
pathogenic
GRCh38/hg38 7q33-35(chr7:135414108-144140219)x1 copy number loss See cases [RCV000054173] Chr7:135414108..144140219 [GRCh38]
Chr7:135098857..143837312 [GRCh37]
Chr7:134749397..143468245 [NCBI36]
Chr7:7q33-35
pathogenic
GRCh38/hg38 7p22.3-q36.3(chr7:54185-159282390)x1 copy number loss See cases [RCV000135401] Chr7:54185..159282390 [GRCh38]
Chr7:54185..159075079 [GRCh37]
Chr7:149268..158767840 [NCBI36]
Chr7:7p22.3-q36.3
pathogenic
GRCh38/hg38 7q21.3-36.3(chr7:97419852-158923762)x3 copy number gain See cases [RCV000136717] Chr7:97419852..158923762 [GRCh38]
Chr7:97049164..158716453 [GRCh37]
Chr7:96887100..158409214 [NCBI36]
Chr7:7q21.3-36.3
pathogenic
GRCh38/hg38 7q33-36.3(chr7:134666829-158591882)x1 copy number loss See cases [RCV000138120] Chr7:134666829..158591882 [GRCh38]
Chr7:134351581..158384574 [GRCh37]
Chr7:134002121..158077335 [NCBI36]
Chr7:7q33-36.3
pathogenic
GRCh38/hg38 7q31.32-36.3(chr7:121863759-159335865)x3 copy number gain See cases [RCV000138847] Chr7:121863759..159335865 [GRCh38]
Chr7:121503813..159128555 [GRCh37]
Chr7:121291049..158821316 [NCBI36]
Chr7:7q31.32-36.3
pathogenic
GRCh38/hg38 7q33-36.1(chr7:135017687-148807400)x1 copy number loss See cases [RCV000138903] Chr7:135017687..148807400 [GRCh38]
Chr7:134702438..148504492 [GRCh37]
Chr7:134352978..148135425 [NCBI36]
Chr7:7q33-36.1
pathogenic
GRCh38/hg38 7q32.3-36.3(chr7:132444095-159335866)x3 copy number gain See cases [RCV000139654] Chr7:132444095..159335866 [GRCh38]
Chr7:132128854..159128556 [GRCh37]
Chr7:131779394..158821317 [NCBI36]
Chr7:7q32.3-36.3
pathogenic
GRCh38/hg38 7q31.2-36.3(chr7:115459015-159325817)x3 copy number gain See cases [RCV000141413] Chr7:115459015..159325817 [GRCh38]
Chr7:115099069..159118507 [GRCh37]
Chr7:114886305..158811268 [NCBI36]
Chr7:7q31.2-36.3
pathogenic
GRCh38/hg38 7q32.3-36.3(chr7:131228764-159335866)x3 copy number gain See cases [RCV000142802] Chr7:131228764..159335866 [GRCh38]
Chr7:130913523..159128556 [GRCh37]
Chr7:130564063..158821317 [NCBI36]
Chr7:7q32.3-36.3
pathogenic
GRCh38/hg38 7q32.3-36.3(chr7:131171478-159327017)x3 copy number gain See cases [RCV000143754] Chr7:131171478..159327017 [GRCh38]
Chr7:130856237..159119707 [GRCh37]
Chr7:130506777..158812468 [NCBI36]
Chr7:7q32.3-36.3
pathogenic
GRCh38/hg38 7q32.3-36.3(chr7:132438072-159327017)x3 copy number gain See cases [RCV000143707] Chr7:132438072..159327017 [GRCh38]
Chr7:132122831..159119707 [GRCh37]
Chr7:131773371..158812468 [NCBI36]
Chr7:7q32.3-36.3
pathogenic
TMEM106B-BRAF fusion deletion Pleomorphic xanthoastrocytoma [RCV000454357] Chr7:12258147..140494267 [GRCh37]
Chr7:7p21.3-q34
pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:43360-159119707)x1 copy number loss See cases [RCV000446044] Chr7:43360..159119707 [GRCh37]
Chr7:7p22.3-q36.3
pathogenic
GRCh37/hg19 7q32.3-34(chr7:131642114-139107211)x1 copy number loss See cases [RCV000448552] Chr7:131642114..139107211 [GRCh37]
Chr7:7q32.3-34
pathogenic
GRCh37/hg19 7q33-36.3(chr7:133799185-159119707)x1 copy number loss See cases [RCV000448836] Chr7:133799185..159119707 [GRCh37]
Chr7:7q33-36.3
pathogenic
GRCh37/hg19 7q22.1-36.3(chr7:98969247-159119707)x3 copy number gain See cases [RCV000447709] Chr7:98969247..159119707 [GRCh37]
Chr7:7q22.1-36.3
pathogenic
GRCh37/hg19 7q32.1-34(chr7:127295698-139524358)x1 copy number loss See cases [RCV000447722] Chr7:127295698..139524358 [GRCh37]
Chr7:7q32.1-34
pathogenic
GRCh37/hg19 7q32.1-36.3(chr7:128276078-159119707)x3 copy number gain See cases [RCV000447956] Chr7:128276078..159119707 [GRCh37]
Chr7:7q32.1-36.3
pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:43361-159119707) copy number gain See cases [RCV000510686] Chr7:43361..159119707 [GRCh37]
Chr7:7p22.3-q36.3
pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:43361-159119707)x3 copy number gain See cases [RCV000511549] Chr7:43361..159119707 [GRCh37]
Chr7:7p22.3-q36.3
pathogenic
GRCh37/hg19 7q33(chr7:134379624-135927947)x3 copy number gain See cases [RCV000511199] Chr7:134379624..135927947 [GRCh37]
Chr7:7q33
uncertain significance
GRCh37/hg19 7q32.1-36.3(chr7:128312450-159119220) copy number gain not provided [RCV000767558] Chr7:128312450..159119220 [GRCh37]
Chr7:7q32.1-36.3
pathogenic
GRCh37/hg19 7q33(chr7:133230189-137972605)x1 copy number loss not provided [RCV000682906] Chr7:133230189..137972605 [GRCh37]
Chr7:7q33
pathogenic
GRCh37/hg19 7q22.1-36.3(chr7:98693388-159119707)x3 copy number gain not provided [RCV000682911] Chr7:98693388..159119707 [GRCh37]
Chr7:7q22.1-36.3
pathogenic
GRCh37/hg19 7q32.3-36.3(chr7:130592554-159119707)x3 copy number gain not provided [RCV000849569] Chr7:130592554..159119707 [GRCh37]
Chr7:7q32.3-36.3
pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:10704-159122532)x3 copy number gain not provided [RCV000746278] Chr7:10704..159122532 [GRCh37]
Chr7:7p22.3-q36.3
pathogenic
Single allele complex Renal transitional cell carcinoma [RCV000754611] Chr7:129367205..140482957 [GRCh37]
Chr7:7q32.2-34
likely pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:44935-159126310)x3 copy number gain not provided [RCV000746280] Chr7:44935..159126310 [GRCh37]
Chr7:7p22.3-q36.3
pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:10365-159119707)x3 copy number gain not provided [RCV000848126] Chr7:10365..159119707 [GRCh37]
Chr7:7p22.3-q36.3
pathogenic
GRCh37/hg19 7q33(chr7:134648448-137942208)x1 copy number loss not provided [RCV000849809] Chr7:134648448..137942208 [GRCh37]
Chr7:7q33
uncertain significance
GRCh37/hg19 7q32.3-36.3(chr7:131414604-159126310)x1 copy number loss See cases [RCV001007432] Chr7:131414604..159126310 [GRCh37]
Chr7:7q32.3-36.3
pathogenic
GRCh37/hg19 7q31.1-36.3(chr7:109251060-159119707)x3 copy number gain not provided [RCV001005994] Chr7:109251060..159119707 [GRCh37]
Chr7:7q31.1-36.3
pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:15827 AgrOrtholog
COSMIC SLC13A4 COSMIC
Ensembl Genes ENSG00000164707 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000297282 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000476620 UniProtKB/TrEMBL
  ENSP00000477467 UniProtKB/TrEMBL
Ensembl Transcript ENST00000354042 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000378428 UniProtKB/TrEMBL
  ENST00000422620 UniProtKB/TrEMBL
GTEx ENSG00000164707 GTEx
HGNC ID HGNC:15827 ENTREZGENE
Human Proteome Map SLC13A4 Human Proteome Map
InterPro SLC13A/DASS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:26266 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 26266 ENTREZGENE
OMIM 604309 OMIM
Pfam Na_sulph_symp UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA38045 PharmGKB
UniProt Q59HF0 ENTREZGENE, UniProtKB/TrEMBL
  Q9UKG4 ENTREZGENE, UniProtKB/Swiss-Prot
  V9GYC7_HUMAN UniProtKB/TrEMBL
  V9GZ66_HUMAN UniProtKB/TrEMBL
UniProt Secondary A4D1Q4 UniProtKB/Swiss-Prot
  Q8N631 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-23 SLC13A4  solute carrier family 13 member 4    solute carrier family 13 (sodium/sulfate symporter), member 4  Symbol and/or name change 5135510 APPROVED
2013-07-23 SLC13A4  solute carrier family 13 (sodium/sulfate symporter), member 4    solute carrier family 13 (sodium/sulfate symporters), member 4  Symbol and/or name change 5135510 APPROVED