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Gene: HSP90AA1 (heat shock protein 90 alpha family class A member 1) Homo sapiens
Symbol: HSP90AA1
Name: heat shock protein 90 alpha family class A member 1
RGD ID: 1347335
Description: Exhibits several functions, including ATP binding activity; enzyme binding activity; and protein domain specific binding activity. Involved in several processes, including cellular protein-containing complex assembly; protein insertion into mitochondrial outer membrane; and regulation of cellular protein metabolic process. Localizes to cytoplasm and protein-containing complex. Biomarker of Alzheimer's disease and rheumatoid arthritis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: EL52; epididymis luminal secretory protein 52; epididymis secretory sperm binding protein Li 65p; FLJ31884; heat shock 86 kDa; heat shock 90kD protein 1, alpha; heat shock 90kD protein 1, alpha-like 4; heat shock 90kD protein, alpha-like 4; heat shock 90kDa protein 1, alpha; heat shock 90kDa protein 1, alpha-like 4; heat shock protein 90kDa alpha (cytosolic), class A member 1; heat shock protein 90kDa alpha family class A member 1; heat shock protein HSP 90-alpha; HEL-S-65p; HSP 86; Hsp103; HSP86; Hsp89; HSP89A; Hsp90; HSP90A; HSP90N; HSPC1; HSPCA; HSPCAL1; HSPCAL4; HSPN; LAP-2; LAP2; lipopolysaccharide-associated protein 2; LPS-associated protein 2; renal carcinoma antigen NY-REN-38
Related Pseudogenes: HSP90AA2P   HSP90AA3P   HSP90AA4P   HSP90AA5P   HSP90AA6P  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl14102,080,738 - 102,139,699 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl14102,080,742 - 102,139,699 (-)EnsemblGRCh38hg38GRCh38
GRCh3814102,080,742 - 102,139,749 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3714102,547,075 - 102,606,086 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3614101,616,828 - 101,675,839 (-)NCBINCBI36hg18NCBI36
Build 3414101,617,144 - 101,623,135NCBI
Celera1482,601,564 - 82,660,582 (-)NCBI
Cytogenetic Map14q32.31NCBI
HuRef1482,725,979 - 82,785,051 (-)NCBIHuRef
CHM1_114102,484,935 - 102,543,941 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on HSP90AA1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1347335
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.