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Gene: FGG (fibrinogen gamma chain) Homo sapiens
Symbol: FGG
Name: fibrinogen gamma chain
Description: Exhibits cell adhesion molecule binding activity; signaling receptor binding activity; and structural molecule activity. Involved in several processes, including blood coagulation; negative regulation of apoptotic process; and positive regulation of secretion by cell. Localizes to the external side of plasma membrane; fibrinogen complex; and platelet alpha granule. Implicated in congenital afibrinogenemia and multiple myeloma. Biomarker of type 2 diabetes mellitus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: fibrinogen, gamma polypeptide; testicular tissue protein Li 70
Mus musculus (house mouse) : Fgg (fibrinogen gamma chain)  MGI  Alliance
Rattus norvegicus (Norway rat) : Fgg (fibrinogen gamma chain)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fgg (fibrinogen gamma chain)
Pan paniscus (bonobo/pygmy chimpanzee) : FGG (fibrinogen gamma chain)
Canis lupus familiaris (dog) : FGG (fibrinogen gamma chain)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fgg (fibrinogen gamma chain)
Sus scrofa (pig) : FGG (fibrinogen gamma chain)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh384154,604,134 - 154,612,808 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh374155,525,286 - 155,533,902 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364155,744,736 - 155,753,352 (-)NCBINCBI36hg18NCBI36
Build 344155,883,339 - 155,891,408NCBI
Celera4152,856,249 - 152,864,865 (-)NCBI
Cytogenetic Map4q32.1NCBI
HuRef4151,265,862 - 151,274,478 (-)NCBIHuRef
CHM1_14155,503,216 - 155,511,890 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on FGG
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731481
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-26
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.