Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-epigallocatechin 3-gallate | multiple interactions | EXP | | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of KLHL9 mRNA | CTD | PMID:22079256 | 1,2-dimethylhydrazine | multiple interactions | ISO | Klhl9 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of KLHL9 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | increases expression | ISO | Klhl9 (Rattus norvegicus) | 6480464 | Ethinyl Estradiol results in increased expression of KLHL9 mRNA | CTD | PMID:29097150 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Klhl9 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of KLHL9 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Klhl9 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of KLHL9 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Klhl9 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of KLHL9 mRNA | CTD | PMID:32109520 | 2-methylcholine | affects expression | EXP | | 6480464 | beta-methylcholine affects the expression of KLHL9 mRNA | CTD | PMID:21179406 | 2-palmitoylglycerol | increases expression | EXP | | 6480464 | 2-palmitoylglycerol results in increased expression of KLHL9 mRNA | CTD | PMID:37199045 | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Klhl9 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of KLHL9 mRNA | CTD | PMID:26251327 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of KLHL9 mRNA | CTD | PMID:28628672 | 5-fluorouracil | affects response to substance | EXP | | 6480464 | KLHL9 protein affects the susceptibility to Fluorouracil | CTD | PMID:16217747 | all-trans-retinoic acid | increases expression | EXP | | 6480464 | Tretinoin results in increased expression of KLHL9 mRNA | CTD | PMID:23724009 | antimycin A | decreases expression | EXP | | 6480464 | Antimycin A results in decreased expression of KLHL9 mRNA | CTD | PMID:33512557 | aristolochic acid A | decreases expression | EXP | | 6480464 | aristolochic acid I results in decreased expression of KLHL9 mRNA | CTD | PMID:33212167 | avobenzone | decreases expression | EXP | | 6480464 | avobenzone results in decreased expression of KLHL9 mRNA | CTD | PMID:31016361 | bisphenol A | affects expression | ISO | Klhl9 (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of KLHL9 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | ISO | Klhl9 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of KLHL9 mRNA | CTD | PMID:32145629 and PMID:34947998 | bisphenol A | increases expression | ISO | Klhl9 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of KLHL9 mRNA | CTD | PMID:33296240 | bisphenol A | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of KLHL9 mRNA | CTD | PMID:28628672 | cadmium atom | multiple interactions | EXP | | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of KLHL9 mRNA | CTD | PMID:35301059 | cadmium dichloride | multiple interactions | EXP | | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of KLHL9 mRNA | CTD | PMID:35301059 | caffeine | affects phosphorylation | EXP | | 6480464 | Caffeine affects the phosphorylation of KLHL9 protein | CTD | PMID:35688186 | captan | decreases expression | ISO | Klhl9 (Mus musculus) | 6480464 | Captan results in decreased expression of KLHL9 mRNA | CTD | PMID:31558096 | CGP 52608 | multiple interactions | EXP | | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to KLHL9 gene] | CTD | PMID:28238834 | cisplatin | decreases expression | ISO | Klhl9 (Rattus norvegicus) | 6480464 | Cisplatin results in decreased expression of KLHL9 mRNA | CTD | PMID:22023808 | cobalt dichloride | decreases expression | EXP | | 6480464 | cobaltous chloride results in decreased expression of KLHL9 mRNA | CTD | PMID:19320972 | copper atom | multiple interactions | EXP | | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of KLHL9 mRNA | CTD | PMID:20971185 | copper(0) | multiple interactions | EXP | | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of KLHL9 mRNA | CTD | PMID:20971185 | crocidolite asbestos | increases methylation | EXP | | 6480464 | Asbestos and Crocidolite results in increased methylation of KLHL9 promoter | CTD | PMID:29626692 | dexamethasone | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of KLHL9 mRNA | CTD | PMID:28628672 | dicrotophos | decreases expression | EXP | | 6480464 | dicrotophos results in decreased expression of KLHL9 mRNA | CTD | PMID:28302478 | elemental selenium | multiple interactions | EXP | | 6480464 | [Selenium co-treated with Vitamin E] results in increased expression of KLHL9 mRNA | CTD | PMID:19244175 | fenthion | decreases expression | ISO | Klhl9 (Mus musculus) | 6480464 | Fenthion results in decreased expression of KLHL9 mRNA | CTD | PMID:34813904 | folic acid | multiple interactions | ISO | Klhl9 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of KLHL9 mRNA | CTD | PMID:22206623 | folpet | decreases expression | ISO | Klhl9 (Mus musculus) | 6480464 | folpet results in decreased expression of KLHL9 mRNA | CTD | PMID:31558096 | glyphosate | increases methylation | ISO | Klhl9 (Rattus norvegicus) | 6480464 | Glyphosate results in increased methylation of KLHL9 gene | CTD | PMID:31011160 | hydralazine | multiple interactions | EXP | | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of KLHL9 mRNA | CTD | PMID:17183730 | indometacin | multiple interactions | EXP | | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of KLHL9 mRNA | CTD | PMID:28628672 | ketamine | decreases expression | ISO | Klhl9 (Rattus norvegicus) | 6480464 | Ketamine results in decreased expression of KLHL9 mRNA | CTD | PMID:20080153 | methapyrilene | decreases expression | ISO | Klhl9 (Rattus norvegicus) | 6480464 | Methapyrilene results in decreased expression of KLHL9 mRNA | CTD | PMID:30467583 | methidathion | decreases expression | ISO | Klhl9 (Mus musculus) | 6480464 | methidathion results in decreased expression of KLHL9 mRNA | CTD | PMID:34813904 | methylmercury chloride | decreases expression | EXP | | 6480464 | methylmercuric chloride results in decreased expression of KLHL9 mRNA | CTD | PMID:28001369 | pirinixic acid | decreases expression | ISO | Klhl9 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of KLHL9 mRNA | CTD | PMID:18445702 | potassium chromate | multiple interactions | EXP | | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of KLHL9 mRNA | CTD | PMID:22079256 | potassium chromate | decreases expression | EXP | | 6480464 | potassium chromate(VI) results in decreased expression of KLHL9 mRNA | CTD | PMID:22079256 | quercetin | decreases expression | EXP | | 6480464 | Quercetin results in decreased expression of KLHL9 mRNA | CTD | PMID:21632981 | rimonabant | multiple interactions | ISO | Klhl9 (Mus musculus) | 6480464 | Rimonabant inhibits the reaction [Dietary Fats results in increased expression of KLHL9 mRNA] | CTD | PMID:19030233 | rotenone | decreases expression | EXP | | 6480464 | Rotenone results in decreased expression of KLHL9 mRNA | CTD | PMID:33512557 | selenium atom | multiple interactions | EXP | | 6480464 | [Selenium co-treated with Vitamin E] results in increased expression of KLHL9 mRNA | CTD | PMID:19244175 | sodium dichromate | decreases expression | ISO | Klhl9 (Mus musculus) | 6480464 | sodium bichromate results in decreased expression of KLHL9 mRNA | CTD | PMID:31558096 | tebufenpyrad | decreases expression | EXP | | 6480464 | 4-chloro-N-((4-(1 and 1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in decreased expression of KLHL9 mRNA | CTD | PMID:33512557 | temozolomide | increases expression | EXP | | 6480464 | Temozolomide results in increased expression of KLHL9 mRNA | CTD | PMID:31758290 | titanium dioxide | increases expression | ISO | Klhl9 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of KLHL9 mRNA | CTD | PMID:23409001 | tributylstannane | increases expression | ISO | Klhl9 (Rattus norvegicus) | 6480464 | tributyltin results in increased expression of KLHL9 mRNA | CTD | PMID:31129395 | trichloroethene | decreases expression | ISO | Klhl9 (Mus musculus) | 6480464 | Trichloroethylene results in decreased expression of KLHL9 mRNA | CTD | PMID:19448997 | trichloroethene | decreases expression | ISO | Klhl9 (Rattus norvegicus) | 6480464 | Trichloroethylene results in decreased expression of KLHL9 mRNA | CTD | PMID:33387578 | urethane | decreases expression | EXP | | 6480464 | Urethane results in decreased expression of KLHL9 mRNA | CTD | PMID:28818685 | valproic acid | multiple interactions | EXP | | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of KLHL9 mRNA | CTD | PMID:17183730 | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of KLHL9 mRNA | CTD | PMID:25979313 | vinclozolin | increases expression | ISO | Klhl9 (Rattus norvegicus) | 6480464 | vinclozolin results in increased expression of KLHL9 mRNA | CTD | PMID:23555832 | vitamin E | multiple interactions | EXP | | 6480464 | [Selenium co-treated with Vitamin E] results in increased expression of KLHL9 mRNA | CTD | PMID:19244175 | |