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Gene: STYXL1 (serine/threonine/tyrosine interacting like 1) Homo sapiens
Symbol: STYXL1
Name: serine/threonine/tyrosine interacting like 1
Description: Exhibits protein phosphatase binding activity; protein phosphatase inhibitor activity; and pseudophosphatase activity. Involved in several processes, including negative regulation of phosphoprotein phosphatase activity; negative regulation of stress granule assembly; and positive regulation of intrinsic apoptotic signaling pathway. Localizes to the mitochondrion; INTERACTS WITH 2-hydroxypropanoic acid; 2-methylcholine; butanal.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: dual specificity phosphatase 24 (putative); dual specificity phosphatase inhibitor MK-STYX; dual specificity protein phosphatase 24; DUSP24; inactive dual specificity protein phosphatase MK-STYX; map kinase phosphatase-like protein MK-STYX; MK-STYX; MKSTYX; serine/threonine/tyrosine interacting-like 1; serine/threonine/tyrosine-interacting-like protein 1
Mus musculus (house mouse) : Styxl1 (serine/threonine/tyrosine interacting-like 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Styxl1 (serine/threonine/tyrosine interacting-like 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Styxl1 (serine/threonine/tyrosine interacting like 1)
Pan paniscus (bonobo/pygmy chimpanzee) : STYXL1 (serine/threonine/tyrosine interacting like 1)
Canis lupus familiaris (dog) : STYXL1 (serine/threonine/tyrosine interacting like 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Styxl1 (serine/threonine/tyrosine interacting like 1)
Sus scrofa (pig) : STYXL1 (serine/threonine/tyrosine interacting like 1)
Chlorocebus sabaeus (African green monkey) : STYXL1 (serine/threonine/tyrosine interacting like 1)
Heterocephalus glaber (naked mole-rat) : Styxl1 (serine/threonine/tyrosine interacting like 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl775,996,338 - 76,048,004 (-)EnsemblGRCh38hg38GRCh38
GRCh38775,995,820 - 76,049,344 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37775,625,610 - 75,677,321 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36775,463,591 - 75,515,257 (-)NCBINCBI36hg18NCBI36
Build 34775,270,306 - 75,321,972NCBI
Celera770,494,194 - 70,545,856 (-)NCBI
Cytogenetic Map7q11.23NCBI
HuRef770,712,490 - 70,763,886 (-)NCBIHuRef
CHM1_1775,555,700 - 75,607,308 (-)NCBICHM1_1
CRA_TCAGchr7v2774,958,719 - 75,010,385 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on STYXL1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1353281
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.