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Gene: PPIL2 (peptidylprolyl isomerase like 2) Homo sapiens
Symbol: PPIL2
Name: peptidylprolyl isomerase like 2
Description: Exhibits ubiquitin-ubiquitin ligase activity. Involved in protein localization to plasma membrane and protein polyubiquitination. Localizes to cytoplasm; nucleoplasm; and plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CYC4; cyclophilin, 60kDa; cyclophilin-60; cyclophilin-like protein CyP-60; Cyp-60; CYP60; FLJ39930; hCyP-60; MGC33174; MGC787; peptidyl-prolyl cis-trans isomerase-like 2; peptidylprolyl cis-trans isomerase; peptidylprolyl isomerase (cyclophilin)-like 2; PPIase; probable inactive peptidyl-prolyl cis-trans isomerase-like 2; RING-type E3 ubiquitin transferase isomerase-like 2; RING-type E3 ubiquitin-protein ligase PPIL2; rotamase PPIL2; U-box domain containing 7; UBOX7
Mus musculus (house mouse) : Ppil2 (peptidylprolyl isomerase (cyclophilin)-like 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ppil2 (peptidylprolyl isomerase like 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ppil2 (peptidylprolyl isomerase like 2)
Pan paniscus (bonobo/pygmy chimpanzee) : PPIL2 (peptidylprolyl isomerase like 2)
Canis lupus familiaris (dog) : PPIL2 (peptidylprolyl isomerase like 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ppil2 (peptidylprolyl isomerase like 2)
Sus scrofa (pig) : PPIL2 (peptidylprolyl isomerase like 2)
Chlorocebus sabaeus (African green monkey) : PPIL2 (peptidylprolyl isomerase like 2)
Heterocephalus glaber (naked mole-rat) : Ppil2 (peptidylprolyl isomerase like 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl2221,666,009 - 21,700,015 (+)EnsemblGRCh38hg38GRCh38
GRCh382221,665,984 - 21,700,015 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372222,020,273 - 22,052,202 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362220,350,273 - 20,382,202 (+)NCBINCBI36hg18NCBI36
Build 342220,344,863 - 20,376,713NCBI
Celera225,837,808 - 5,869,733 (+)NCBI
Cytogenetic Map22q11.21NCBI
HuRef224,978,170 - 5,009,851 (+)NCBIHuRef
CHM1_12222,020,457 - 22,052,396 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PPIL2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1319848
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.