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Gene: PCSK7 (proprotein convertase subtilisin/kexin type 7) Homo sapiens
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Symbol: PCSK7
Name: proprotein convertase subtilisin/kexin type 7
Description: Exhibits peptidase activity. Involved in protein processing. Localizes to integral component of Golgi membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ23503; FLJ45329; hPC8; LPC; lymphoma proprotein convertase; PC7; PC8; prohormone convertase 7; prohormone convertase 8, subtilisin-like; prohormone convertase PC7; proprotein convertase 7; proprotein convertase 8; proprotein convertase PC7; proprotein convertase subtilisin / kexin, type 7; proprotein convertase subtilisin/kexin type 7 precursor variant 2; SPC7; subtilisin/kexin-like protease PC7
Orthologs:
Mus musculus (house mouse) : Pcsk7 (proprotein convertase subtilisin/kexin type 7)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pcsk7 (proprotein convertase subtilisin/kexin type 7)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pcsk7 (proprotein convertase subtilisin/kexin type 7)
Canis lupus familiaris (dog) : PCSK7 (proprotein convertase subtilisin/kexin type 7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pcsk7 (proprotein convertase subtilisin/kexin type 7)
Sus scrofa (pig) : PCSK7 (proprotein convertase subtilisin/kexin type 7)
Chlorocebus sabaeus (African green monkey) : PCSK7 (proprotein convertase subtilisin/kexin type 7)
Heterocephalus glaber (naked mole-rat) : Pcsk7 (proprotein convertase subtilisin/kexin type 7)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl11117,204,337 - 117,232,525 (-)EnsemblGRCh38hg38GRCh38
GRCh3811117,201,156 - 117,232,525 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3711117,075,788 - 117,102,811 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611116,580,998 - 116,608,021 (-)NCBINCBI36hg18NCBI36
Build 3411116,580,999 - 116,608,021NCBI
Celera11114,233,408 - 114,260,470 (-)NCBI
Cytogenetic Map11q23.3NCBI
HuRef11113,008,583 - 113,035,606 (-)NCBIHuRef
CHM1_111116,960,619 - 116,988,075 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on PCSK7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733505
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.