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Gene: MSN (moesin) Homo sapiens
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Symbol: MSN
Name: moesin
Description: Exhibits several functions, including cell adhesion molecule binding activity; double-stranded RNA binding activity; and protein kinase binding activity. Involved in several processes, including cellular response to testosterone stimulus; epithelial cell differentiation; and positive regulation of macromolecule metabolic process. Localizes to several cellular components, including the invadopodium; microvillus; and pseudopodium. Colocalizes with the focal adhesion. Implicated in primary immunodeficiency disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: epididymis luminal protein 70; HEL70; IMD50; membrane-organizing extension spike protein
Orthologs:
Mus musculus (house mouse) : Msn (moesin)  MGI  Alliance
Rattus norvegicus (Norway rat) : Msn (moesin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Msn (moesin)
Pan paniscus (bonobo/pygmy chimpanzee) : MSN (moesin)
Canis lupus familiaris (dog) : MSN (moesin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Msn (moesin)
Sus scrofa (pig) : MSN (moesin)
Chlorocebus sabaeus (African green monkey) : MSN (moesin)
Heterocephalus glaber (naked mole-rat) : Msn (moesin)
more info ...
Related Pseudogenes: MSNP1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 EnsemblX65,588,377 - 65,741,931 (+)Ensembl
GRCh38X65,588,382 - 65,741,931 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X64,808,257 - 64,961,793 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X64,804,236 - 64,878,518 (+)NCBINCBI36hg18NCBI36
Build 34X64,670,531 - 64,744,813NCBI
CeleraX65,234,645 - 65,308,924 (+)NCBI
Cytogenetic MapXq12NCBI
HuRefX58,715,854 - 58,790,104 (+)NCBIHuRef
CHM1_1X64,780,526 - 64,854,813 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on MSN
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732547
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.