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Gene: RASSF1 (Ras association domain family member 1) Homo sapiens
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Symbol: RASSF1
Name: Ras association domain family member 1
Description: Exhibits identical protein binding activity; protein N-terminus binding activity; and protein heterodimerization activity. Involved in several processes, including negative regulation of cell cycle; positive regulation of protein ubiquitination; and protein stabilization. Localizes to the microtubule cytoskeleton and nucleus. Implicated in breast cancer; reproductive organ cancer (multiple); transitional cell carcinoma; and urinary system cancer (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 123F2; cardiac-specific ras association domain family 1 protein; NORE2A; pancreas-specific ras association domain family 1 protein; Ras association (RalGDS/AF-6) domain family 1; Ras association (RalGDS/AF-6) domain family member 1; Ras association domain family protein 1; ras association domain-containing protein 1; RASSF1A; RDA32; REH3P21; tumor suppressor protein RDA32; WUGSC:H_LUCA12.5
Orthologs:
Mus musculus (house mouse) : Rassf1 (Ras association (RalGDS/AF-6) domain family member 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rassf1 (Ras association domain family member 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rassf1 (Ras association domain family member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : RASSF1 (Ras association domain family member 1)
Canis lupus familiaris (dog) : RASSF1 (Ras association domain family member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rassf1 (Ras association domain family member 1)
Sus scrofa (pig) : RASSF1 (Ras association domain family member 1)
Chlorocebus sabaeus (African green monkey) : RASSF1 (Ras association domain family member 1)
Heterocephalus glaber (naked mole-rat) : Rassf1 (Ras association domain family member 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl350,329,782 - 50,340,980 (-)EnsemblGRCh38hg38GRCh38
GRCh38350,329,786 - 50,340,936 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37350,367,217 - 50,378,367 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36350,342,221 - 50,353,371 (-)NCBINCBI36hg18NCBI36
Build 34350,342,220 - 50,353,371NCBI
Celera350,340,051 - 50,351,201 (-)NCBI
Cytogenetic Map3p21.31NCBI
HuRef350,422,848 - 50,433,998 (-)NCBIHuRef
CHM1_1350,319,475 - 50,330,627 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
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Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on RASSF1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1343966
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-03-24
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.