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Gene: PRMT1 (protein arginine methyltransferase 1) Homo sapiens
Symbol: PRMT1
Name: protein arginine methyltransferase 1
Description: Exhibits several functions, including S-adenosyl-L-methionine binding activity; methyl-CpG binding activity; and protein-arginine N-methyltransferase activity. Involved in several processes, including histone H4-R3 methylation; protein homooligomerization; and regulation of myeloid cell differentiation. Localizes to the methylosome and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ANM1; HCP1; heterogeneous nuclear ribonucleoprotein methyltransferase 1-like 2; heterogeneous nuclear ribonucleoproteins methyltransferase-like 2 (s. cerevisiae); histone-arginine N-methyltransferase PRMT1; HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 2; HMT1 hnRNP methyltransferase-like 2; HRMT1L2; interferon receptor 1-bound protein 4; IR1B4; protein arginine N-methyltransferase 1
Mus musculus (house mouse) : Prmt1 (protein arginine N-methyltransferase 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Prmt1 (protein arginine methyltransferase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prmt1 (protein arginine methyltransferase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PRMT1 (protein arginine methyltransferase 1)
Canis lupus familiaris (dog) : PRMT1 (protein arginine methyltransferase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prmt1 (protein arginine methyltransferase 1)
Sus scrofa (pig) : PRMT1 (protein arginine methyltransferase 1)
Chlorocebus sabaeus (green monkey) : PRMT1 (protein arginine methyltransferase 1)
Heterocephalus glaber (naked mole-rat) : Prmt1 (protein arginine methyltransferase 1)
more info ...
Related Pseudogenes: PRMT1P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1949,675,786 - 49,689,029 (+)Ensembl
GRCh381949,676,166 - 49,688,450 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371950,180,409 - 50,191,707 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361954,872,308 - 54,883,516 (+)NCBINCBI36hg18NCBI36
Build 341954,872,354 - 54,883,516NCBI
Celera1947,049,830 - 47,061,036 (+)NCBI
Cytogenetic Map19q13.33NCBI
HuRef1946,557,181 - 46,568,351 (+)NCBIHuRef
CHM1_11950,182,198 - 50,193,506 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on PRMT1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731338
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.