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Gene: CHMP2A (charged multivesicular body protein 2A) Homo sapiens
Symbol: CHMP2A
Name: charged multivesicular body protein 2A
Description: CHMP2A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM, Mar 2008]
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BC-2; BC2; CHMP2; chromatin modifying protein 2A; chromatin-modifying protein 2a; hVps2-1; putative breast adenocarcinoma marker (32kD); putative breast adenocarcinoma marker BC-2; vacuolar protein sorting-associated protein 2-1; VPS2; VPS2 homolog A; vps2-1; VPS2A
Mus musculus (house mouse) : Chmp2a (charged multivesicular body protein 2A)  MGI  Alliance
Rattus norvegicus (Norway rat) : Chmp2a (charged multivesicular body protein 2A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Chmp2a (charged multivesicular body protein 2A)
Pan paniscus (bonobo/pygmy chimpanzee) : CHMP2A (charged multivesicular body protein 2A)
Canis lupus familiaris (dog) : CHMP2A (charged multivesicular body protein 2A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Chmp2a (charged multivesicular body protein 2A)
Sus scrofa (pig) : CHMP2A (charged multivesicular body protein 2A)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381958,551,566 - 58,555,624 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371959,062,933 - 59,066,495 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361963,754,745 - 63,758,298 (-)NCBINCBI36hg18NCBI36
Celera1956,106,112 - 56,109,665 (-)NCBI
Cytogenetic Map19q13.43NCBI
HuRef1955,373,170 - 55,376,723 (-)NCBIHuRef
CHM1_11959,056,762 - 59,060,320 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CHMP2A
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1603659
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2019-10-08
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.