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Gene: RUVBL1 (RuvB like AAA ATPase 1) Homo sapiens
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Symbol: RUVBL1
Name: RuvB like AAA ATPase 1
Description: Exhibits DNA helicase activity; TBP-class protein binding activity; and transcription coactivator activity. Involved in histone H2A acetylation; histone H4 acetylation; and positive regulation of canonical Wnt signaling pathway. Localizes to the R2TP complex; cytosol; and nuclear lumen.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 49 kDa TATA box-binding protein-interacting protein; 49 kDa TBP-interacting protein; 54 kDa erythrocyte cytosolic protein; ECP-54; ECP54; INO80 complex subunit H; INO80H; NMP 238; NMP238; nuclear matrix protein 238; pontin; pontin 52; Pontin52; RuvB (E coli homolog)-like 1; ruvB-like 1; RuvB-like AAA ATPase; RuvB-like AAA ATPase 1; ruvb-like protein 1; RVB1; TAP54-alpha; TATA binding protein interacting protein 49 kDa; TIH1; TIP49; TIP49A; TIP60-associated protein 54-alpha
Orthologs:
Mus musculus (house mouse) : Ruvbl1 (RuvB-like protein 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ruvbl1 (RuvB-like AAA ATPase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ruvbl1 (RuvB like AAA ATPase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : RUVBL1 (RuvB like AAA ATPase 1)
Canis lupus familiaris (dog) : RUVBL1 (RuvB like AAA ATPase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ruvbl1 (RuvB like AAA ATPase 1)
Sus scrofa (pig) : RUVBL1 (RuvB like AAA ATPase 1)
Chlorocebus sabaeus (African green monkey) : RUVBL1 (RuvB like AAA ATPase 1)
Heterocephalus glaber (naked mole-rat) : Ruvbl1 (RuvB like AAA ATPase 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl3128,064,778 - 128,153,914 (-)Ensembl
GRCh383128,064,611 - 128,153,914 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh373127,799,800 - 127,872,752 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363129,282,493 - 129,325,332 (-)NCBINCBI36hg18NCBI36
Build 343129,282,500 - 129,325,340NCBI
Celera3126,230,848 - 126,272,604 (-)NCBI
Cytogenetic Map3q21.3NCBI
HuRef3125,180,247 - 125,223,118 (-)NCBIHuRef
CHM1_13127,746,833 - 127,835,772 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on RUVBL1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 68537
Created: 2001-07-11
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.