(+)-schisandrin B multiple interactions ISO RGD:70896 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of CES1D mRNA] CTD PMID:31150632 (+)-trans-(S)-allethrin increases metabolic processing EXP 6480464 CES1 protein results in increased metabolism of bioallethrin CTD PMID:19249324 (25R)-cholest-5-ene-3beta,26-diol decreases activity EXP 6480464 27-hydroxycholesterol results in decreased activity of CES1 protein CTD PMID:19761868 (25R)-cholest-5-ene-3beta,26-diol multiple interactions EXP 6480464 27-hydroxycholesterol inhibits the reaction [CES1 protein results in increased metabolism of bioresmethrin] CTD PMID:19761868 (4-nitrophenyl)acetic acid increases hydrolysis EXP 6480464 CES1 protein results in increased hydrolysis of 4-nitrophenylacetic acid CTD PMID:11950785 1,2-dibromoethane increases expression ISO RGD:735261 6480464 Ethylene Dibromide results in increased expression of CES1 mRNA CTD PMID:17311802 1,2-dichloroethane decreases expression ISO RGD:735261 6480464 ethylene dichloride results in decreased expression of CES1D mRNA CTD PMID:28189721 1,2-dimethylhydrazine decreases expression ISO RGD:70896 6480464 1, 2-Dimethylhydrazine results in decreased expression of CES1D mRNA CTD PMID:27840820 1-benzofuran increases expression ISO RGD:735261 6480464 benzofuran results in increased expression of CES1 mRNA CTD PMID:17311802 1-benzofuran affects expression ISO RGD:735261 6480464 benzofuran affects the expression of CES1 mRNA CTD PMID:17114358 1-chloro-2,4-dinitrobenzene increases expression EXP 6480464 Dinitrochlorobenzene results in increased expression of CES1 mRNA CTD PMID:19524605 1-naphthyl isothiocyanate decreases expression ISO RGD:70896 6480464 1-Naphthylisothiocyanate results in decreased expression of CES1D mRNA CTD PMID:30723492 17beta-estradiol decreases expression ISO RGD:735261 6480464 Estradiol results in decreased expression of CES1 mRNA CTD PMID:19484750 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:735261 6480464 [2 more ... CTD PMID:23457121 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO RGD:70896 6480464 2 more ... CTD PMID:27291303 2,2-Bis(bromomethyl)propane-1,3-diol increases expression ISO RGD:735261 6480464 2 more ... CTD PMID:17311802 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of CES1 mRNA CTD PMID:22574217 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:735261 6480464 Tetrachlorodibenzodioxin results in decreased expression of CES1D mRNA CTD PMID:28238261 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:735261 6480464 Tetrachlorodibenzodioxin affects the expression of CES1 mRNA more ... CTD PMID:21570461 more ... 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:735261 6480464 Tetrachlorodibenzodioxin results in increased expression of CES1 mRNA CTD PMID:19770486 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO RGD:70896 6480464 Tetrachlorodibenzodioxin results in decreased expression of CES1D mRNA CTD PMID:21215274 2,4,6-trinitrobenzenesulfonic acid increases expression EXP 6480464 Trinitrobenzenesulfonic Acid results in increased expression of CES1 mRNA CTD PMID:19524605 , PMID:22609641 2,4,6-trinitrobenzenesulfonic acid multiple interactions ISO RGD:735261 6480464 Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CES1 mRNA] CTD PMID:18200517 2,4,6-trinitrobenzenesulfonic acid decreases expression ISO RGD:735261 6480464 Trinitrobenzenesulfonic Acid results in decreased expression of CES1 mRNA CTD PMID:18200517 2-(chloromethyl)pyridine increases expression ISO RGD:735261 6480464 2-chloromethylpyridine results in increased expression of CES1 mRNA CTD PMID:17311802 2-arachidonoylglycerol multiple interactions EXP 6480464 [CES1 protein results in increased hydrolysis of glyceryl 2-arachidonate] which results in increased chemical synthesis of Arachidonic Acid CTD PMID:21049984 2-arachidonoylglycerol increases hydrolysis EXP 6480464 CES1 protein results in increased hydrolysis of glyceryl 2-arachidonate CTD PMID:21049984 2-hydroxypropanoic acid decreases expression EXP 6480464 Lactic Acid results in decreased expression of CES1 mRNA CTD PMID:30851411 2-naphthol affects metabolic processing EXP 6480464 CES1 protein affects the metabolism of 2-naphthol CTD PMID:12837533 2-nitrophenol affects metabolic processing EXP 6480464 CES1 protein affects the metabolism of 2-nitrophenol CTD PMID:12837533 2-tert-butylhydroquinone increases expression EXP 6480464 2-tert-butylhydroquinone results in increased expression of CES1 mRNA alternative form CTD PMID:19715681 2-tert-butylhydroquinone multiple interactions EXP 6480464 2-tert-butylhydroquinone results in increased expression of and results in increased activity of CES1 protein alternative form, NFE2L2 protein affects the reaction [2-tert-butylhydroquinone results in increased expression of CES1 mRNA alternative form] CTD PMID:19715681 26-hydroxycholesterol multiple interactions EXP 6480464 27-hydroxycholesterol inhibits the reaction [CES1 protein results in increased metabolism of bioresmethrin] CTD PMID:19761868 26-hydroxycholesterol decreases activity EXP 6480464 27-hydroxycholesterol results in decreased activity of CES1 protein CTD PMID:19761868 3,3',4,4',5-pentachlorobiphenyl multiple interactions ISO RGD:735261 6480464 [3 more ... CTD PMID:23457121 3,3',4,4',5-pentachlorobiphenyl decreases expression ISO RGD:70896 6480464 3 more ... CTD PMID:19692669 3-chloropropane-1,2-diol increases expression ISO RGD:70896 6480464 alpha-Chlorohydrin analog results in increased expression of CES1 protein, alpha-Chlorohydrin results in increased expression of CES1 protein CTD PMID:26072098 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:735261 6480464 [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of CES1D mRNA CTD PMID:24848799 3-methylcholanthrene decreases expression EXP 6480464 Methylcholanthrene results in decreased expression of CES1 protein CTD PMID:10640517 4,4'-diaminodiphenylmethane increases expression ISO RGD:735261 6480464 4, 4'-diaminodiphenylmethane results in increased expression of CES1 mRNA CTD PMID:18648102 4-hydroxynon-2-enal decreases activity EXP 6480464 4-hydroxy-2-nonenal results in decreased activity of CES1 protein CTD PMID:21878322 4-hydroxyphenyl retinamide decreases expression ISO RGD:735261 6480464 Fenretinide results in decreased expression of CES1 mRNA CTD PMID:28973697 4-methylumbelliferyl acetate multiple interactions EXP 6480464 Atropine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-methylumbelliferyl acetate] more ... CTD PMID:9311626 4-methylumbelliferyl acetate increases hydrolysis EXP 6480464 CES1 protein results in increased hydrolysis of 4-methylumbelliferyl acetate CTD PMID:9311626 4-nitrophenol multiple interactions EXP 6480464 [CES1 protein results in increased hydrolysis of 4-nitrophenyl acetate] which results in increased chemical synthesis of 4-nitrophenol CTD PMID:20097249 4-nitrophenol affects metabolic processing EXP 6480464 CES1 protein affects the metabolism of 4-nitrophenol CTD PMID:12837533 4-nitrophenol increases chemical synthesis EXP 6480464 CES1 protein results in increased chemical synthesis of 4-nitrophenol CTD PMID:20097249 4-nitrophenyl acetate increases hydrolysis EXP 6480464 CES1 protein results in increased hydrolysis of 4-nitrophenyl acetate CTD PMID:10518925 , PMID:20097249 4-nitrophenyl acetate multiple interactions EXP 6480464 [CES1 protein results in increased hydrolysis of 4-nitrophenyl acetate] which results in increased chemical synthesis of 4-nitrophenol more ... CTD PMID:16282638 , PMID:20097249 4-nitrophenyl acetate increases metabolic processing EXP 6480464 CES1 protein results in increased metabolism of 4-nitrophenyl acetate CTD PMID:18485328 4-nitrophenyl acetate decreases metabolic processing EXP 6480464 CES1 gene mutant form results in decreased metabolism of 4-nitrophenyl acetate CTD PMID:18485328 5'-Deoxy-5-fluorocytidine increases chemical synthesis EXP 6480464 CES1 protein results in increased chemical synthesis of 5'-deoxy-5-fluorocytidine CTD PMID:15687373 6-Acetylmorphine affects binding EXP 6480464 6-O-monoacetylmorphine binds to CES1 protein CTD PMID:9311626 6-Acetylmorphine multiple interactions EXP 6480464 Cocaine inhibits the reaction [CES1 protein results in increased chemical synthesis of 6-O-monoacetylmorphine] CTD PMID:8930175 6-Acetylmorphine increases chemical synthesis EXP 6480464 CES1 protein results in increased chemical synthesis of 6-O-monoacetylmorphine CTD PMID:8930175 , PMID:9311626 acetylsalicylic acid multiple interactions EXP 6480464 CES1 protein promotes the reaction [Aspirin results in increased expression of ACACA protein modified form], CES1 protein promotes the reaction [Aspirin results in increased expression of PRKAA1 protein modified form] CTD PMID:25743752 acridines decreases activity EXP 6480464 Acridines results in decreased activity of CES1 protein CTD PMID:23123248 acrylamide increases expression ISO RGD:70896 6480464 Acrylamide results in increased expression of CES1D mRNA CTD PMID:28959563 Actein decreases expression ISO RGD:70896 6480464 actein results in decreased expression of CES1 protein CTD PMID:29969672 aflatoxin B1 decreases expression ISO RGD:735261 6480464 Aflatoxin B1 results in decreased expression of CES1 mRNA CTD PMID:19770486 aflatoxin B1 increases methylation EXP 6480464 Aflatoxin B1 results in increased methylation of CES1 intron CTD PMID:30157460 amiodarone increases expression EXP 6480464 Amiodarone results in increased expression of CES1 mRNA CTD PMID:21163907 ampicillin increases expression EXP 6480464 Ampicillin results in increased expression of CES1 mRNA CTD PMID:22609641 aniracetam increases hydrolysis EXP 6480464 CES1 protein results in increased hydrolysis of aniracetam CTD PMID:9300133 arachidonic acid decreases activity EXP 6480464 Arachidonic Acid results in decreased activity of CES1 protein CTD PMID:19761868 arachidonic acid multiple interactions EXP 6480464 [CES1 protein results in increased hydrolysis of glyceryl 2-arachidonate] which results in increased chemical synthesis of Arachidonic Acid CTD PMID:21049984 aripiprazole multiple interactions EXP 6480464 Aripiprazole inhibits the reaction [CES1 protein results in increased hydrolysis of 4-nitrophenyl acetate], Aripiprazole inhibits the reaction [CES1 protein results in increased hydrolysis of Methylphenidate] CTD PMID:20097249 aripiprazole multiple interactions ISO RGD:735261 6480464 Aripiprazole inhibits the reaction [CES1 protein results in increased hydrolysis of Methylphenidate] CTD PMID:20097249 asbestos increases expression EXP 6480464 Asbestos results in increased expression of CES1 mRNA CTD PMID:22398240 atropine multiple interactions EXP 6480464 Atropine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-methylumbelliferyl acetate] CTD PMID:9311626 avobenzone increases expression EXP 6480464 avobenzone results in increased expression of CES1 mRNA CTD PMID:31016361 azinphos-methyl decreases activity EXP 6480464 Azinphosmethyl results in decreased activity of CES1 protein CTD PMID:26790371 benzene increases expression ISO RGD:735261 6480464 Benzene results in increased expression of CES1 mRNA CTD PMID:17311802 benzo[a]pyrene decreases expression ISO RGD:735261 6480464 Benzo(a)pyrene results in decreased expression of CES1D mRNA CTD PMID:23735875 benzo[a]pyrene increases expression ISO RGD:735261 6480464 Benzo(a)pyrene results in increased expression of CES1 mRNA CTD PMID:19770486 , PMID:20127859 Benzo[k]fluoranthene increases expression ISO RGD:735261 6480464 benzo(k)fluoranthene results in increased expression of CES1 mRNA CTD PMID:26377693 benzylpenicillin increases expression EXP 6480464 Penicillin G results in increased expression of CES1 mRNA CTD PMID:22609641 beta-hexachlorocyclohexane increases expression ISO RGD:735261 6480464 beta-hexachlorocyclohexane results in increased expression of CES1D mRNA CTD PMID:25270620 bioresmethrin multiple interactions EXP 6480464 27-hydroxycholesterol inhibits the reaction [CES1 protein results in increased metabolism of bioresmethrin] CTD PMID:19761868 bioresmethrin increases hydrolysis ISO RGD:70896 6480464 CES1 protein results in increased hydrolysis of bioresmethrin CTD PMID:16387282 bioresmethrin increases hydrolysis ISO RGD:735261 6480464 CES1 protein results in increased hydrolysis of bioresmethrin CTD PMID:16387282 bioresmethrin increases metabolic processing EXP 6480464 CES1 protein results in increased metabolism of bioresmethrin CTD PMID:19249324 , PMID:19761868 bioresmethrin increases hydrolysis EXP 6480464 CES1 protein results in increased hydrolysis of bioresmethrin CTD PMID:16387282 bis(2-ethylhexyl) phthalate increases expression ISO RGD:735261 6480464 Diethylhexyl Phthalate results in increased expression of CES1D mRNA CTD PMID:19850644 bis(2-ethylhexyl) phthalate multiple interactions ISO RGD:735261 6480464 PPARA protein promotes the reaction [Diethylhexyl Phthalate results in increased expression of CES1D mRNA] CTD PMID:19850644 bis-4-nitrophenyl phosphate decreases activity EXP 6480464 bis(4-nitrophenyl)phosphate results in decreased activity of CES1 protein CTD PMID:23123248 bisphenol A increases expression ISO RGD:70896 6480464 bisphenol A results in increased expression of CES1 mRNA CTD PMID:25181051 bisphenol A increases methylation ISO RGD:70896 6480464 bisphenol A results in increased methylation of CES1D gene CTD PMID:28505145 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of CES1 mRNA CTD PMID:27685785 Bisphenol A glycidylmethacrylate increases expression EXP 6480464 Bisphenol A-Glycidyl Methacrylate results in increased expression of CES1 mRNA CTD PMID:21951919 Bisphenol A glycidylmethacrylate multiple interactions EXP 6480464 CAT protein inhibits the reaction [Bisphenol A-Glycidyl Methacrylate results in increased expression of CES1 mRNA] CTD PMID:21951919 bleomycin A2 decreases expression ISO RGD:70896 6480464 Bleomycin results in decreased expression of CES1 protein CTD PMID:25933445 buta-1,3-diene increases expression ISO RGD:735261 6480464 1, 3-butadiene results in increased expression of CES1D mRNA CTD PMID:29038090 butanal decreases expression EXP 6480464 butyraldehyde results in decreased expression of CES1 mRNA CTD PMID:26079696 butylated hydroxyanisole increases expression EXP 6480464 Butylated Hydroxyanisole results in increased expression of CES1 mRNA CTD PMID:18227147 butylated hydroxyanisole decreases expression ISO RGD:735261 6480464 Butylated Hydroxyanisole results in decreased expression of CES1D protein CTD PMID:26179144 cadmium dichloride decreases expression ISO RGD:70896 6480464 Cadmium Chloride results in decreased expression of CES1D mRNA CTD PMID:25993096 capecitabine multiple interactions EXP 6480464 CES1 protein results in increased hydrolysis of and results in increased activity of Capecitabine CTD PMID:15687373 carbon nanotube decreases expression ISO RGD:735261 6480464 Nanotubes, Carbon analog results in decreased expression of CES1D mRNA, Nanotubes, Carbon results in decreased expression of CES1D mRNA CTD PMID:25554681 chloroprene increases expression ISO RGD:735261 6480464 Chloroprene results in increased expression of CES1D mRNA CTD PMID:23125180 chlorpyrifos decreases activity EXP 6480464 Chlorpyrifos results in decreased activity of CES1 protein CTD PMID:26790371 chlorpyrifos decreases activity ISO RGD:70896 6480464 Chlorpyrifos results in decreased activity of CES1 protein CTD PMID:24373905 cholesterol increases metabolic processing EXP 6480464 CES1 protein results in increased metabolism of Cholesterol CTD PMID:11015575 more ... cholesterol increases abundance ISO RGD:70896 6480464 CES1 protein results in increased abundance of Cholesterol CTD PMID:15825828 cholesterol increases expression EXP 6480464 Cholesterol results in increased expression of CES1 mRNA CTD PMID:8049197 choline multiple interactions ISO RGD:735261 6480464 [Choline deficiency co-treated with Methionine deficiency] results in increased expression of CES1D mRNA, Methionine inhibits the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased expression of CES1D mRNA] CTD PMID:25178843 chromium trinitrate increases expression ISO RGD:735261 6480464 chromium nitrate results in increased expression of CES1D protein CTD PMID:22144121 ciglitazone decreases expression EXP 6480464 ciglitazone results in decreased expression of CES1 mRNA CTD PMID:11409902 ciguatoxin CTX1B affects expression ISO RGD:735261 6480464 Ciguatoxins affects the expression of CES1 mRNA CTD PMID:18353800 clofibrate increases expression ISO RGD:735261 6480464 Clofibrate results in increased expression of CES1D mRNA CTD PMID:17585979 clofibrate increases expression ISO RGD:70896 6480464 Clofibrate results in increased expression of CES1 protein CTD PMID:16470657 clofibrate multiple interactions ISO RGD:735261 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of CES1D mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of CES1D mRNA] CTD PMID:17585979 clofibric acid multiple interactions ISO RGD:70896 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CES1 mRNA CTD PMID:17602206 cobalt dichloride increases expression ISO RGD:70896 6480464 cobaltous chloride results in increased expression of CES1D mRNA CTD PMID:24386269 cocaine multiple interactions EXP 6480464 CES1 protein results in increased metabolism of [Cocaine co-treated with Ethanol] more ... CTD PMID:12773168 more ... cocaine increases hydrolysis EXP 6480464 CES1 protein results in increased hydrolysis of Cocaine CTD PMID:12679808 more ... cocaine affects binding EXP 6480464 Cocaine binds to CES1 protein CTD PMID:9311626 copper(II) sulfate increases expression EXP 6480464 Copper Sulfate results in increased expression of CES1 mRNA CTD PMID:19549813 coumarin increases expression ISO RGD:735261 6480464 coumarin results in increased expression of CES1 mRNA CTD PMID:17311802 curcumin multiple interactions ISO RGD:735261 6480464 Curcumin inhibits the reaction [Trinitrobenzenesulfonic Acid results in decreased expression of CES1 mRNA] CTD PMID:18200517 cyclosporin A increases expression EXP 6480464 Cyclosporine results in increased expression of CES1 mRNA CTD PMID:21163907 cyclosporin A decreases expression ISO RGD:735261 6480464 Cyclosporine results in decreased expression of CES1 mRNA, Cyclosporine results in decreased expression of CES1 protein CTD PMID:19770486 , PMID:23308384 cyhalothrin multiple interactions EXP 6480464 CES1 protein inhibits the reaction [cyhalothrin results in increased activity of NR1I2 protein] CTD PMID:19249324 cyhalothrin increases metabolic processing EXP 6480464 CES1 protein results in increased metabolism of cyhalothrin CTD PMID:19249324 cylindrospermopsin decreases expression EXP 6480464 cylindrospermopsin results in decreased expression of CES1 mRNA CTD PMID:23726867 cypermethrin increases hydrolysis EXP 6480464 CES1 protein results in increased hydrolysis of cypermethrin CTD PMID:16359636 Delapril hydrochloride multiple interactions EXP 6480464 CES1 protein results in increased hydrolysis of and results in increased activity of delapril CTD PMID:9300133 deoxycholic acid decreases expression ISO RGD:735261 6480464 Deoxycholic Acid results in decreased expression of CES1D mRNA CTD PMID:23911798 dexamethasone increases expression EXP 6480464 Dexamethasone results in increased expression of CES1 mRNA, Dexamethasone results in increased expression of CES1 protein CTD PMID:10640517 , PMID:25047013 dexamethasone multiple interactions ISO RGD:735261 6480464 [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased expression of CES1D mRNA CTD PMID:24848799 dexamethasone decreases expression ISO RGD:70896 6480464 Dexamethasone results in decreased expression of CES1 mRNA, Dexamethasone results in decreased expression of CES1 protein CTD PMID:10640517 dexamethasone decreases expression ISO RGD:735261 6480464 Dexamethasone results in decreased expression of CES1D mRNA CTD PMID:22429928 dextran sulfate multiple interactions ISO RGD:735261 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CES1D mRNA CTD PMID:29950665 dextropropoxyphene affects binding EXP 6480464 Dextropropoxyphene binds to CES1 protein CTD PMID:10381793 diclofenac decreases expression ISO RGD:735261 6480464 Diclofenac results in decreased expression of CES1D mRNA CTD PMID:26934552 diethyl maleate increases reduction ISO RGD:735261 6480464 diethyl maleate results in increased reduction of CES1D protein CTD PMID:19843705 diethyl maleate decreases expression ISO RGD:70896 6480464 diethyl maleate results in decreased expression of CES1D protein CTD PMID:21161181 dimethocaine increases hydrolysis EXP 6480464 CES1 protein results in increased hydrolysis of dimethocaine CTD PMID:25445008 dioxygen multiple interactions ISO RGD:735261 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of CES1D mRNA CTD PMID:30529165 diuron decreases expression ISO RGD:70896 6480464 Diuron results in decreased expression of CES1D mRNA CTD PMID:25152437 diuron increases expression ISO RGD:70896 6480464 Diuron results in increased expression of CES1D mRNA CTD PMID:21551480 ecgonine benzoate increases chemical synthesis EXP 6480464 CES1 protein results in increased chemical synthesis of benzoylecgonine CTD PMID:9311626 elemental selenium increases expression EXP 6480464 Selenium results in increased expression of CES1 mRNA CTD PMID:19244175 entinostat increases expression EXP 6480464 entinostat results in increased expression of CES1 mRNA CTD PMID:27188386 ethanol multiple interactions EXP 6480464 CES1 protein results in increased metabolism of [Cocaine co-treated with Ethanol] CTD PMID:12773168 , PMID:9311626 etoposide increases expression ISO RGD:735261 6480464 Etoposide results in increased expression of CES1D mRNA CTD PMID:25270620 everolimus decreases activity EXP 6480464 Everolimus results in decreased activity of CES1 protein CTD PMID:24727322 fenofibrate multiple interactions ISO RGD:70896 6480464 [Fenofibrate co-treated with Diethylnitrosamine] results in decreased expression of CES1 mRNA CTD PMID:18253720 fenvalerate increases metabolic processing EXP 6480464 CES1 protein results in increased metabolism of fenvalerate CTD PMID:19249324 fluoxetine multiple interactions EXP 6480464 Fluoxetine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-nitrophenyl acetate], Fluoxetine inhibits the reaction [CES1 protein results in increased hydrolysis of Methylphenidate] CTD PMID:20097249 flutamide increases expression ISO RGD:70896 6480464 Flutamide results in increased expression of CES1D mRNA CTD PMID:24793618 fumonisin B1 increases expression ISO RGD:735261 6480464 fumonisin B1 results in increased expression of CES1 mRNA CTD PMID:16221962 furan decreases expression ISO RGD:70896 6480464 furan results in decreased expression of CES1D mRNA CTD PMID:25539665 galaxolide decreases activity EXP 6480464 galaxolide results in decreased activity of CES1 protein CTD PMID:22489002 glafenine decreases expression ISO RGD:70896 6480464 Glafenine results in decreased expression of CES1D mRNA CTD PMID:24136188 heroin decreases acetylation EXP 6480464 CES1 protein results in decreased acetylation of Heroin CTD PMID:9311626 heroin increases hydrolysis EXP 6480464 CES1 protein results in increased hydrolysis of Heroin CTD PMID:12679808 more ... heroin affects binding EXP 6480464 Heroin binds to CES1 protein CTD PMID:9311626 heroin multiple interactions EXP 6480464 Cocaine inhibits the reaction [CES1 protein results in increased hydrolysis of Heroin] CTD PMID:8930175 Homatropine multiple interactions EXP 6480464 CES1 protein binds to and results in increased metabolism of homatropine CTD PMID:12679808 Homatropine affects binding EXP 6480464 homatropine binds to CES1 protein CTD PMID:12773168 hydroquinone increases expression EXP 6480464 hydroquinone results in increased expression of CES1 mRNA CTD PMID:31256213 imidapril multiple interactions EXP 6480464 CES1 protein results in increased hydrolysis of and results in increased activity of imidapril CTD PMID:9300133 Imidapril hydrochloride multiple interactions EXP 6480464 CES1 protein results in increased hydrolysis of and results in increased activity of imidapril CTD PMID:9300133 irinotecan increases response to substance EXP 6480464 CES1 mRNA results in increased susceptibility to Irinotecan CTD PMID:15239142 irinotecan increases hydrolysis EXP 6480464 CES1 protein results in increased hydrolysis of Irinotecan CTD PMID:15100172 kojic acid multiple interactions ISO RGD:70896 6480464 [Diethylnitrosamine co-treated with kojic acid] results in increased expression of CES1 mRNA CTD PMID:18544905 L-methionine multiple interactions ISO RGD:735261 6480464 [Choline deficiency co-treated with Methionine deficiency] results in increased expression of CES1D mRNA, Methionine inhibits the reaction [[Choline deficiency co-treated with Methionine deficiency] results in increased expression of CES1D mRNA] CTD PMID:25178843 L-methionine increases expression ISO RGD:735261 6480464 Methionine deficiency results in increased expression of CES1D mRNA CTD PMID:25178843 lidocaine increases hydrolysis ISO RGD:70896 6480464 CES1D protein results in increased hydrolysis of Lidocaine CTD PMID:12019189 lipopolysaccharide multiple interactions EXP 6480464 prolinedithiocarbamate inhibits the reaction [Lipopolysaccharides results in decreased expression of CES1 mRNA], SB 203580 inhibits the reaction [Lipopolysaccharides results in decreased expression of CES1 mRNA] CTD PMID:21237253 lipopolysaccharide decreases expression ISO RGD:735261 6480464 Lipopolysaccharides results in decreased expression of CES1D mRNA CTD PMID:27339419 lipopolysaccharide decreases expression EXP 6480464 Lipopolysaccharides results in decreased expression of CES1 mRNA, Lipopolysaccharides results in decreased expression of CES1 protein CTD PMID:21237253 lithocholic acid multiple interactions ISO RGD:735261 6480464 Pregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in decreased expression of CES1D mRNA] CTD PMID:20359477 lithocholic acid decreases expression ISO RGD:735261 6480464 Lithocholic Acid results in decreased expression of CES1D mRNA CTD PMID:20359477 Magnolol multiple interactions EXP 6480464 magnolol binds to and results in decreased activity of CES1 protein CTD PMID:31170387 malathion increases expression ISO RGD:735261 6480464 Malathion results in increased expression of CES1 mRNA CTD PMID:17311802 Meperidine affects binding EXP 6480464 Meperidine binds to CES1 protein CTD PMID:10381793 Meperidine increases hydrolysis EXP 6480464 CES1 protein results in increased hydrolysis of Meperidine CTD PMID:10381793 methylphenidate multiple interactions EXP 6480464 [CES1 protein results in increased hydrolysis of Methylphenidate] which results in increased chemical synthesis of ritalinic acid more ... CTD PMID:18485328 , PMID:20097249 methylphenidate increases hydrolysis EXP 6480464 CES1 protein results in increased hydrolysis of Methylphenidate CTD PMID:15082749 more ... methylphenidate multiple interactions ISO RGD:735261 6480464 aripiprazole inhibits the reaction [CES1 protein results in increased hydrolysis of Methylphenidate] CTD PMID:20097249 methylphenidate increases metabolic processing EXP 6480464 CES1 protein results in increased metabolism of Methylphenidate CTD PMID:18485328 Mitragynine increases hydrolysis EXP 6480464 CES1 protein results in increased hydrolysis of mitragynine CTD PMID:25445008 monoethylglycinexylidide increases hydrolysis ISO RGD:70896 6480464 CES1D protein results in increased hydrolysis of monoethylglycinexylidide CTD PMID:12019189 N-(1-naphthyl)ethylenediamine increases expression ISO RGD:735261 6480464 N-(1-naphthyl)ethylenediamine results in increased expression of CES1 mRNA CTD PMID:17311802 N-acetyl-beta-D-glucosamine increases expression EXP 6480464 Acetylglucosamine results in increased expression of CES1 mRNA CTD PMID:18047607 N-acetyl-D-glucosamine increases expression EXP 6480464 Acetylglucosamine results in increased expression of CES1 mRNA CTD PMID:18047607 N-Methylolacrylamide increases expression ISO RGD:735261 6480464 N-methylolacrylamide results in increased expression of CES1 mRNA CTD PMID:17311802 N-nitrosodiethylamine multiple interactions ISO RGD:735261 6480464 [2 more ... CTD PMID:23457121 N-nitrosodiethylamine decreases expression ISO RGD:70896 6480464 Diethylnitrosamine results in decreased expression of CES1D mRNA CTD PMID:19041683 N-nitrosodiethylamine multiple interactions ISO RGD:70896 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of CES1 mRNA more ... CTD PMID:17602206 more ... N-nitrosodimethylamine increases expression EXP 6480464 Dimethylnitrosamine results in increased expression of CES1 mRNA CTD PMID:17547211 naloxone multiple interactions EXP 6480464 CES1 protein binds to and results in increased metabolism of Naloxone CTD PMID:12679808 naloxone affects binding EXP 6480464 Naloxone binds to CES1 protein CTD PMID:12773168 naphthalene-1,5-diamine affects expression ISO RGD:735261 6480464 1, 5-naphthalenediamine affects the expression of CES1 mRNA CTD PMID:17114358 naphthalene-1,5-diamine increases expression ISO RGD:735261 6480464 1, 5-naphthalenediamine results in increased expression of CES1 mRNA CTD PMID:17311802 nickel atom decreases expression EXP 6480464 Nickel results in decreased expression of CES1 mRNA CTD PMID:25583101 ochratoxin A decreases expression ISO RGD:70896 6480464 ochratoxin A results in decreased expression of CES1 mRNA CTD PMID:16251485 okadaic acid decreases expression ISO RGD:735261 6480464 Okadaic Acid results in decreased expression of CES1D mRNA CTD PMID:25270620 oltipraz increases expression ISO RGD:735261 6480464 oltipraz results in increased expression of CES1 mRNA CTD PMID:30114225 oltipraz multiple interactions ISO RGD:735261 6480464 NFE2L2 protein promotes the reaction [oltipraz results in increased expression of CES1 mRNA] CTD PMID:30114225 oseltamivir affects hydrolysis EXP 6480464 CES1 protein affects the hydrolysis of Oseltamivir CTD PMID:18983829 oxazepam increases expression ISO RGD:735261 6480464 Oxazepam results in increased expression of CES1D mRNA CTD PMID:12727805 p-nitrophenyl butyrate multiple interactions EXP 6480464 CES1 protein binds to and results in increased hydrolysis of 4-nitrophenyl butyrate CTD PMID:16282638 p-nitrophenyl butyrate increases hydrolysis EXP 6480464 CES1 protein results in increased hydrolysis of 4-nitrophenyl butyrate CTD PMID:11950785 palmitoyl-CoA increases hydrolysis ISO RGD:70896 6480464 CES1 protein results in increased hydrolysis of Palmitoyl Coenzyme A CTD PMID:8611161 paracetamol affects expression ISO RGD:735261 6480464 Acetaminophen affects the expression of CES1D mRNA CTD PMID:17562736 paracetamol decreases expression ISO RGD:735261 6480464 Acetaminophen results in decreased expression of CES1D mRNA CTD PMID:29246445 paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of CES1 mRNA CTD PMID:26690555 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of CES1 mRNA CTD PMID:21163907 , PMID:22230336 paracetamol multiple interactions ISO RGD:735261 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of CES1D mRNA more ... CTD PMID:17585979 , PMID:29246445 paraoxon decreases activity EXP 6480464 Paraoxon results in decreased activity of CES1 protein CTD PMID:11950785 , PMID:25250848 paricalcitol multiple interactions EXP 6480464 [Phosphorus co-treated with paricalcitol] results in increased expression of CES1 mRNA CTD PMID:17715259 pentachloronitrobenzene increases expression ISO RGD:735261 6480464 quintozene results in increased expression of CES1 mRNA CTD PMID:17311802 pentane-2,3-dione decreases expression ISO RGD:70896 6480464 2, 3-pentanedione results in decreased expression of CES1D mRNA CTD PMID:25710175 perfluorooctane-1-sulfonic acid affects expression ISO RGD:735261 6480464 perfluorooctane sulfonic acid affects the expression of CES1 mRNA CTD PMID:19429403 perfluorooctanoic acid affects expression ISO RGD:735261 6480464 perfluorooctanoic acid affects the expression of CES1 mRNA CTD PMID:18281256 , PMID:19429403 perfluorooctanoic acid increases expression ISO RGD:735261 6480464 perfluorooctanoic acid results in increased expression of CES1D mRNA CTD PMID:30685356 permethrin affects hydrolysis EXP 6480464 CES1 protein affects the hydrolysis of Permethrin CTD PMID:18983829 permethrin increases hydrolysis ISO RGD:70896 6480464 CES1 protein results in increased hydrolysis of Permethrin CTD PMID:16387282 permethrin increases hydrolysis ISO RGD:735261 6480464 CES1 protein results in increased hydrolysis of Permethrin CTD PMID:16387282 permethrin increases hydrolysis EXP 6480464 CES1 protein results in increased hydrolysis of Permethrin CTD PMID:16359636 , PMID:16387282 perphenazine multiple interactions EXP 6480464 Perphenazine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-nitrophenyl acetate], Perphenazine inhibits the reaction [CES1 protein results in increased hydrolysis of Methylphenidate] CTD PMID:20097249 phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of CES1 protein CTD PMID:10640517 phenobarbital affects expression ISO RGD:735261 6480464 Phenobarbital affects the expression of CES1D mRNA CTD PMID:23091169 phenobarbital increases expression ISO RGD:735261 6480464 Phenobarbital results in increased expression of CES1D mRNA, Phenobarbital results in increased expression of CES1D protein CTD PMID:22513142 more ... phenobarbital increases hydrolysis ISO RGD:735261 6480464 CES1D protein results in increased hydrolysis of Phenobarbital CTD PMID:22513142 phenobarbital multiple interactions ISO RGD:735261 6480464 Phenobarbital results in increased expression of and results in increased activity of CES1D protein CTD PMID:22513142 phenoxymethylpenicillin increases expression EXP 6480464 Penicillin V results in increased expression of CES1 mRNA CTD PMID:22609641 phenylmethanesulfonyl fluoride decreases activity EXP 6480464 Phenylmethylsulfonyl Fluoride results in decreased activity of CES1 protein CTD PMID:11950785 phosphatidylcholine decreases expression ISO RGD:735261 6480464 Phosphatidylcholines results in decreased expression of CES1D mRNA CTD PMID:23911798 phosphorus atom multiple interactions EXP 6480464 [Phosphorus co-treated with paricalcitol] results in increased expression of CES1 mRNA CTD PMID:17715259 phosphorus(.) multiple interactions EXP 6480464 [Phosphorus co-treated with paricalcitol] results in increased expression of CES1 mRNA CTD PMID:17715259 pioglitazone increases expression EXP 6480464 pioglitazone results in increased expression of CES1 mRNA CTD PMID:15381068 pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of CES1 mRNA CTD PMID:11409902 pirinixic acid multiple interactions ISO RGD:735261 6480464 PPARA protein promotes the reaction [pirinixic acid results in increased expression of CES1 mRNA] CTD PMID:20059764 pirinixic acid increases expression ISO RGD:735261 6480464 pirinixic acid results in increased expression of CES1 mRNA, pirinixic acid results in increased expression of CES1D mRNA CTD PMID:12727805 more ... potassium chromate increases expression ISO RGD:735261 6480464 potassium chromate(VI) results in increased expression of CES1D protein CTD PMID:22144121 potassium dichromate affects expression ISO RGD:735261 6480464 Potassium Dichromate affects the expression of CES1 mRNA CTD PMID:23608068 pregnenolone 16alpha-carbonitrile multiple interactions ISO RGD:735261 6480464 Pregnenolone Carbonitrile inhibits the reaction [Lithocholic Acid results in decreased expression of CES1D mRNA] CTD PMID:20359477 pregnenolone 16alpha-carbonitrile increases expression ISO RGD:735261 6480464 Pregnenolone Carbonitrile results in increased expression of CES1D mRNA, Pregnenolone Carbonitrile results in increased expression of CES1D protein CTD PMID:20359477 more ... Propiverine affects binding ISO RGD:70896 6480464 propiverine binds to CES1D protein CTD PMID:29273565 prostaglandin F2alpha increases hydrolysis EXP 6480464 CES1 protein results in increased hydrolysis of Dinoprost CTD PMID:21049984 prostaglandin J2 decreases expression EXP 6480464 9-deoxy-delta-9-prostaglandin D2 results in decreased expression of CES1 mRNA CTD PMID:11409902 protein kinase inhibitor multiple interactions EXP 6480464 Protein Kinase Inhibitors inhibits the reaction [gardiquimod results in increased expression of CES1 mRNA] CTD PMID:28003376 rac-lactic acid decreases expression EXP 6480464 Lactic Acid results in decreased expression of CES1 mRNA CTD PMID:30851411 ramipril increases hydrolysis EXP 6480464 CES1 protein results in increased hydrolysis of Ramipril CTD PMID:25445008 rifampicin increases expression EXP 6480464 Rifampin results in increased expression of CES1 protein CTD PMID:10640517 ritalinic acid increases chemical synthesis EXP 6480464 CES1 protein results in increased chemical synthesis of ritalinic acid CTD PMID:20097249 ritalinic acid multiple interactions EXP 6480464 [CES1 protein results in increased hydrolysis of Methylphenidate] which results in increased chemical synthesis of ritalinic acid CTD PMID:20097249 rivastigmine decreases activity EXP 6480464 Rivastigmine results in decreased activity of CES1 protein CTD PMID:23123248 sarin multiple interactions EXP 6480464 CES1 protein affects the metabolism of and results in decreased activity of Sarin CTD PMID:12679808 SB 203580 multiple interactions EXP 6480464 SB 203580 inhibits the reaction [Lipopolysaccharides results in decreased expression of CES1 mRNA] CTD PMID:21237253 Se-methyl-L-selenocysteine increases expression EXP 6480464 selenomethylselenocysteine results in increased expression of CES1 CTD PMID:15897249 Se-methylselenocysteine increases expression EXP 6480464 selenomethylselenocysteine results in increased expression of CES1 CTD PMID:15897249 selenium atom increases expression EXP 6480464 Selenium results in increased expression of CES1 mRNA CTD PMID:19244175 sodium arsenite increases expression ISO RGD:70896 6480464 sodium arsenite results in increased expression of CES1D protein CTD PMID:29459688 sodium cholate increases expression ISO RGD:735261 6480464 Sodium Cholate results in increased expression of CES1 mRNA CTD PMID:9565681 sodium dichromate increases expression ISO RGD:70896 6480464 sodium bichromate results in increased expression of CES1D mRNA CTD PMID:12325037 sodium dichromate decreases expression ISO RGD:70896 6480464 sodium bichromate results in decreased expression of CES1D mRNA CTD PMID:25993096 sodium fluoride decreases expression ISO RGD:735261 6480464 Sodium Fluoride results in decreased expression of CES1D protein CTD PMID:28918527 Soman multiple interactions EXP 6480464 CES1 protein affects the metabolism of and results in decreased activity of Soman CTD PMID:12679808 sulforaphane multiple interactions EXP 6480464 NFE2L2 protein affects the reaction [sulforafan results in increased expression of CES1 mRNA alternative form] more ... CTD PMID:19715681 sulforaphane increases expression EXP 6480464 sulforafan results in increased expression of CES1 mRNA, sulforafan results in increased expression of CES1 mRNA alternative form CTD PMID:19715681 , PMID:26833863 tacrine decreases activity EXP 6480464 Tacrine analog results in decreased activity of CES1 protein CTD PMID:12725862 tacrine affects binding EXP 6480464 Tacrine binds to CES1 protein CTD PMID:12725862 Temocapril hydrochloride increases hydrolysis EXP 6480464 CES1 protein results in increased hydrolysis of temocapril hydrochloride CTD PMID:15908471 , PMID:9300133 Temocaprilat increases chemical synthesis EXP 6480464 CES1 protein results in increased chemical synthesis of temocaprilat CTD PMID:15908471 tetrachloromethane decreases expression ISO RGD:735261 6480464 Carbon Tetrachloride results in decreased expression of CES1D mRNA CTD PMID:27339419 tetrachloromethane multiple interactions ISO RGD:70896 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of CES1D mRNA] CTD PMID:31150632 tetrachloromethane decreases expression ISO RGD:70896 6480464 Carbon Tetrachloride results in decreased expression of CES1D mRNA CTD PMID:31150632 thioacetamide decreases expression ISO RGD:70896 6480464 Thioacetamide results in decreased expression of CES1D mRNA CTD PMID:23411599 thioridazine multiple interactions EXP 6480464 Thioridazine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-nitrophenyl acetate], Thioridazine inhibits the reaction [CES1 protein results in increased hydrolysis of Methylphenidate] CTD PMID:20097249 titanium dioxide decreases expression ISO RGD:735261 6480464 titanium dioxide results in decreased expression of CES1D mRNA CTD PMID:23557971 titanium dioxide multiple interactions ISO RGD:735261 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of CES1D mRNA CTD PMID:29950665 tributylstannane increases expression ISO RGD:735261 6480464 tributyltin results in increased expression of CES1D mRNA CTD PMID:24848799 troglitazone increases expression ISO RGD:70896 6480464 troglitazone results in increased expression of CES1D protein CTD PMID:21315101 Tropacocaine multiple interactions EXP 6480464 tropacocaine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-methylumbelliferyl acetate] CTD PMID:9311626 tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate multiple interactions EXP 6480464 Atropine inhibits the reaction [CES1 protein results in increased hydrolysis of 4-methylumbelliferyl acetate] CTD PMID:9311626 valproic acid decreases methylation EXP 6480464 Valproic Acid results in decreased methylation of CES1 gene CTD PMID:29154799 valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of CES1 mRNA CTD PMID:28001369 vinclozolin decreases expression ISO RGD:70896 6480464 vinclozolin results in decreased expression of CES1D mRNA CTD PMID:23034163 vitamin E increases expression EXP 6480464 Vitamin E results in increased expression of CES1 mRNA CTD PMID:19244175 zinc atom decreases expression ISO RGD:735261 6480464 Zinc deficiency results in decreased expression of CES1D mRNA CTD PMID:20857495 zinc atom decreases expression ISO RGD:70896 6480464 Zinc deficiency results in decreased expression of CES1D mRNA CTD PMID:12672911 more ... zinc atom multiple interactions ISO RGD:70896 6480464 Zinc inhibits the reaction [Zinc deficiency results in decreased expression of CES1D mRNA] CTD PMID:16140947 zinc(0) decreases expression ISO RGD:735261 6480464 Zinc deficiency results in decreased expression of CES1D mRNA CTD PMID:20857495 zinc(0) multiple interactions ISO RGD:70896 6480464 Zinc inhibits the reaction [Zinc deficiency results in decreased expression of CES1D mRNA] CTD PMID:16140947 zinc(0) decreases expression ISO RGD:70896 6480464 Zinc deficiency results in decreased expression of CES1D mRNA CTD PMID:12672911 more ...
Gene-Chemical Interaction Annotations
