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Gene: SGSM3 (small G protein signaling modulator 3) Homo sapiens
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Symbol: SGSM3
Name: small G protein signaling modulator 3
Description: Exhibits GTPase activator activity and Rab GTPase binding activity. Involved in several processes, including Rap protein signal transduction; plasma membrane to endosome transport; and regulation of Rab protein signal transduction. Localizes to cytosol; INTERACTS WITH 5-aza-2'-deoxycytidine; aflatoxin B1; atrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CIP85; DKFZp761D051; MAP; merlin binding protein; merlin-associated protein; rab-GTPase-activating protein-like protein; RabGAP-5; RABGAP5; rabGAPLP; RUN and SH3 containing 3; RUN and TBC1 domain containing 3; RUN and TBC1 domain-containing protein 3; RUSC3; RUTBC3; small G protein signaling modulator 3 protein
Orthologs:
Mus musculus (house mouse) : Sgsm3 (small G protein signaling modulator 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Sgsm3 (small G protein signaling modulator 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Sgsm3 (small G protein signaling modulator 3)
Pan paniscus (bonobo/pygmy chimpanzee) : SGSM3 (small G protein signaling modulator 3)
Canis lupus familiaris (dog) : SGSM3 (small G protein signaling modulator 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Sgsm3 (small G protein signaling modulator 3)
Sus scrofa (pig) : SGSM3 (small G protein signaling modulator 3)
Chlorocebus sabaeus (African green monkey) : SGSM3 (small G protein signaling modulator 3)
Heterocephalus glaber (naked mole-rat) : Sgsm3 (small G protein signaling modulator 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2240,370,591 - 40,410,289 (+)EnsemblGRCh38hg38GRCh38
GRCh382240,370,584 - 40,410,289 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372240,766,571 - 40,806,293 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362239,096,541 - 39,136,239 (+)NCBINCBI36hg18NCBI36
Build 342239,091,094 - 39,130,793NCBI
Celera2224,568,657 - 24,608,354 (+)NCBI
Cytogenetic Map22q13.1NCBI
HuRef2223,729,704 - 23,769,396 (+)NCBIHuRef
CHM1_12240,725,458 - 40,765,196 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on SGSM3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1353613
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.