Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: NRF1 (nuclear respiratory factor 1) Homo sapiens
Analyze
Symbol: NRF1
Name: nuclear respiratory factor 1
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and RNA polymerase II core promoter sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Localizes to cytosol and nucleoplasm. Implicated in Huntington's disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: alpha palindromic-binding protein; ALPHA-PAL; NRF-1
Orthologs:
Mus musculus (house mouse) : Nrf1 (nuclear respiratory factor 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nrf1 (nuclear respiratory factor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nrf1 (nuclear respiratory factor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NRF1 (nuclear respiratory factor 1)
Canis lupus familiaris (dog) : NRF1 (nuclear respiratory factor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nrf1 (nuclear respiratory factor 1)
Sus scrofa (pig) : NRF1 (nuclear respiratory factor 1)
Chlorocebus sabaeus (African green monkey) : NRF1 (nuclear respiratory factor 1)
Heterocephalus glaber (naked mole-rat) : Nrf1 (nuclear respiratory factor 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Note: NRF1 (Gene ID: 4899) and NFE2L1 (Gene ID: 4779) share the NRF1 symbol/alias in common. NRF1 is a widely used alternative name for nuclear factor, erythroid 2 like 1 (NFE2L1), which can be confused with the official symbol for nuclear respiratory factor 1 (NRF1). [05 Jul 2018]
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl7129,611,720 - 129,757,082 (+)EnsemblGRCh38hg38GRCh38
GRCh387129,611,720 - 129,757,082 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh377129,251,555 - 129,396,922 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367129,038,791 - 129,184,158 (+)NCBINCBI36hg18NCBI36
Build 347128,845,547 - 128,989,805NCBI
Celera7124,047,294 - 124,192,656 (+)NCBI
Cytogenetic Map7q32.2NCBI
HuRef7123,613,242 - 123,758,239 (+)NCBIHuRef
CHM1_17129,185,024 - 129,330,325 (+)NCBICHM1_1
CRA_TCAGchr7v27128,635,837 - 128,781,204 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on NRF1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1312137
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-05-19
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.