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Gene: PSIP1 (PC4 and SFRS1 interacting protein 1) Homo sapiens
Symbol: PSIP1
Name: PC4 and SFRS1 interacting protein 1
Description: Exhibits activating transcription factor binding activity; chromatin binding activity; and transcription coactivator activity. Involved in mRNA 5'-splice site recognition and positive regulation of transcription by RNA polymerase II. Localizes to nuclear heterochromatin; nuclear periphery; and nucleoplasm; INTERACTS WITH (-)-epigallocatechin 3-gallate; 17beta-estradiol; 5-aza-2'-deoxycytidine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CLL-associated antigen KW-7; dense fine speckles 70 kDa protein; DFS 70; DFS70; LEDGF; lens epithelium-derived growth factor; MGC74712; p52; p75; PAIP; PC4 and SFRS1-interacting protein; PSIP2; transcriptional coactivator p52/p75; transcriptional coactivator p75/p52
Mus musculus (house mouse) : Psip1 (PC4 and SFRS1 interacting protein 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Psip1 (PC4 and SFRS1 interacting protein 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Psip1 (PC4 and SFRS1 interacting protein 1)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100979736 (PC4 and SFRS1-interacting protein)
Canis lupus familiaris (dog) : PSIP1 (PC4 and SFRS1 interacting protein 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Psip1 (PC4 and SFRS1 interacting protein 1)
Sus scrofa (pig) : PSIP1 (PC4 and SFRS1 interacting protein 1)
Chlorocebus sabaeus (African green monkey) : PSIP1 (PC4 and SFRS1 interacting protein 1)
Heterocephalus glaber (naked mole-rat) : Psip1 (PC4 and SFRS1 interacting protein 1)
more info ...
Related Pseudogenes: PSIP1P1   PSIP1P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl915,464,066 - 15,510,995 (-)EnsemblGRCh38hg38GRCh38
GRCh38915,464,066 - 15,511,019 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37915,464,064 - 15,511,003 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36915,454,064 - 15,500,982 (-)NCBINCBI36hg18NCBI36
Build 34915,454,065 - 15,500,982NCBI
Celera915,397,404 - 15,444,340 (-)NCBI
Cytogenetic Map9p22.3NCBI
HuRef915,427,681 - 15,474,611 (-)NCBIHuRef
CHM1_1915,464,652 - 15,511,604 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on PSIP1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1350264
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.