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Gene: CXCL1 (C-X-C motif chemokine ligand 1) Homo sapiens
Symbol: CXCL1
Name: C-X-C motif chemokine ligand 1
Description: Predicted to have CXCR chemokine receptor binding activity and chemokine activity. Involved in antimicrobial humoral immune response mediated by antimicrobial peptide and killing of cells of other organism. Predicted to localize to extracellular space. Biomarker of asthma; chronic obstructive pulmonary disease; common cold; cystic fibrosis; and hyperhomocysteinemia.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C-X-C motif chemokine 1; chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha); fibroblast secretory protein; FSP; GRO-alpha(1-73); GRO1; GRO1 oncogene (melanoma growth stimulating activity, alpha); GRO1 oncogene (melanoma growth-stimulating activity); GROa; growth-regulated alpha protein; melanoma growth stimulating activity, alpha; melanoma growth stimulatory activity alpha; MGSA; MGSA alpha; MGSA-a; NAP-3; neutrophil-activating protein 3; SCYB1
Mus musculus (house mouse) : Cxcl3 (chemokine (C-X-C motif) ligand 3)  MGI  Alliance
Mus musculus (house mouse) : Cxcl1 (chemokine (C-X-C motif) ligand 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cxcl1 (C-X-C motif chemokine ligand 1)  Alliance
Rattus norvegicus (Norway rat) : Cxcl3 (C-X-C motif chemokine ligand 3)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : CXCL1 (C-X-C motif chemokine ligand 1)
Chlorocebus sabaeus (African green monkey) : CXCL1 (C-X-C motif chemokine ligand 1)
more info ...
Related Pseudogenes: CXCL1P1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl473,869,393 - 73,871,308 (+)EnsemblGRCh38hg38GRCh38
GRCh38473,869,393 - 73,871,308 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37474,735,109 - 74,737,019 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36474,953,973 - 74,955,817 (+)NCBINCBI36hg18NCBI36
Build 34475,100,143 - 75,101,988NCBI
Celera472,095,237 - 72,097,087 (+)NCBI
Cytogenetic Map4q13.3NCBI
HuRef470,546,248 - 70,548,158 (+)NCBIHuRef
CHM1_1474,771,032 - 74,772,942 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CXCL1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1343759
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-06-23
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.