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Gene: NFIC (nuclear factor I C) Homo sapiens
Symbol: NFIC
Name: nuclear factor I C
Description: The protein encoded by this gene belongs to the CTF/NF-I family. These are dimeric DNA-binding proteins, and function as cellular transcription factors and as replication factors for adenovirus DNA replication. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CCAAT-binding transcription factor; CCAAT-box-binding transcription factor; CTF; CTF5; MGC20153; NF-I; NF-I/C; NF1-C; NFI; NFI-C; nuclear factor 1 C-type; nuclear factor 1/C; nuclear factor i/c; nuclear factor I/C (CCAAT-binding transcription factor); TGGCA-binding protein
Mus musculus (house mouse) : Nfic (nuclear factor I/C)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nfic (nuclear factor I/C)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nfic (nuclear factor I C)
Pan paniscus (bonobo/pygmy chimpanzee) : NFIC (nuclear factor I C)
Canis lupus familiaris (dog) : NFIC (nuclear factor I C)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nfic (nuclear factor I C)
Sus scrofa (pig) : NFIC (nuclear factor I C)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38193,359,630 - 3,469,217 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37193,359,561 - 3,469,215 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36193,310,616 - 3,414,603 (+)NCBINCBI36hg18NCBI36
Build 34193,317,572 - 3,414,603NCBI
Celera193,296,412 - 3,400,416 (+)NCBI
Cytogenetic Map19p13.3NCBI
HuRef193,125,600 - 3,235,130 (+)NCBIHuRef
CHM1_1193,359,193 - 3,468,863 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on NFIC
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69148
Created: 2001-11-08
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.